MX2016009771A - Metodos y productos para la produccion y administracion de acido nucleico. - Google Patents
Metodos y productos para la produccion y administracion de acido nucleico.Info
- Publication number
- MX2016009771A MX2016009771A MX2016009771A MX2016009771A MX2016009771A MX 2016009771 A MX2016009771 A MX 2016009771A MX 2016009771 A MX2016009771 A MX 2016009771A MX 2016009771 A MX2016009771 A MX 2016009771A MX 2016009771 A MX2016009771 A MX 2016009771A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- nucleic acids
- cells
- products
- therapeutics
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 7
- 108020004707 nucleic acids Proteins 0.000 title abstract 7
- 102000039446 nucleic acids Human genes 0.000 title abstract 7
- 150000007523 nucleic acids Chemical class 0.000 title abstract 7
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 3
- 239000002537 cosmetic Substances 0.000 abstract 2
- 238000010362 genome editing Methods 0.000 abstract 2
- 230000001939 inductive effect Effects 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000008672 reprogramming Effects 0.000 abstract 1
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Abstract
La presente invención se refiere, en parte, a ácidos nucleicos, inclusive ácidos nucleicos que codifican proteínas, agentes terapéuticos y cosméticos que comprenden ácidos nucleicos, métodos para administrar ácidos nucleicos a células, tejidos, árganos y pacientes, métodos para inducir que las células expresen proteínas mediante el uso de ácidos nucleicos, kits y dispositivos para transfectar, realizar la edición génica y reprogramar células, y células, organismos y agentes terapéuticos y cosméticos producidos mediante el uso de estos métodos, kits y dispositivos. Se describen métodos y productos para alterar la secuencia de ADN de una célula, así como también métodos y productos para inducir que las células expresen proteínas, mediante el uso de moléculas sintéticas de ARN, inclusive células presentes in vivo. También se describen agentes terapéuticos que comprenden ácidos nucleicos que codifican proteínas de edición génica.
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