KR101680906B1 - 항체 정상영역 개변체 - Google Patents

항체 정상영역 개변체 Download PDF

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KR101680906B1
KR101680906B1 KR1020107008918A KR20107008918A KR101680906B1 KR 101680906 B1 KR101680906 B1 KR 101680906B1 KR 1020107008918 A KR1020107008918 A KR 1020107008918A KR 20107008918 A KR20107008918 A KR 20107008918A KR 101680906 B1 KR101680906 B1 KR 101680906B1
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KR20100074221A (ko
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도모유키 이가와
히로타케 시라이와
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추가이 세이야쿠 가부시키가이샤
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/53—Hinge
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020107008918A 2007-09-26 2008-09-26 항체 정상영역 개변체 Active KR101680906B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007250147 2007-09-26
JPJP-P-2007-250147 2007-09-26
PCT/JP2008/067483 WO2009041613A1 (ja) 2007-09-26 2008-09-26 抗体定常領域改変体

Related Child Applications (1)

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KR1020167032250A Division KR101922788B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체

Publications (2)

Publication Number Publication Date
KR20100074221A KR20100074221A (ko) 2010-07-01
KR101680906B1 true KR101680906B1 (ko) 2016-11-30

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ID=40511493

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KR1020107008918A Active KR101680906B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체
KR1020217006046A Active KR102339457B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체
KR1020167032250A Active KR101922788B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체
KR1020187033614A Active KR102119108B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체
KR1020217040531A Active KR102467302B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체
KR1020207015247A Active KR102225009B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체

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KR1020217006046A Active KR102339457B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체
KR1020167032250A Active KR101922788B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체
KR1020187033614A Active KR102119108B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체
KR1020217040531A Active KR102467302B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체
KR1020207015247A Active KR102225009B1 (ko) 2007-09-26 2008-09-26 항체 정상영역 개변체

Country Status (22)

Country Link
US (3) US9688762B2 (https=)
EP (4) EP3059246B1 (https=)
JP (9) JP5484060B2 (https=)
KR (6) KR101680906B1 (https=)
CN (1) CN101874041B (https=)
AR (4) AR068563A1 (https=)
AU (1) AU2008304748C1 (https=)
CA (5) CA3222170A1 (https=)
CL (1) CL2008002886A1 (https=)
DK (2) DK3059246T3 (https=)
ES (2) ES2566957T3 (https=)
IL (1) IL204537A0 (https=)
MX (2) MX2010003450A (https=)
MY (3) MY180713A (https=)
PE (1) PE20090711A1 (https=)
PH (3) PH12014502106A1 (https=)
PL (1) PL3059246T3 (https=)
RU (2) RU2526512C2 (https=)
SG (2) SG10201605394SA (https=)
TW (2) TWI464262B (https=)
WO (1) WO2009041613A1 (https=)
ZA (1) ZA201002422B (https=)

Cited By (3)

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KR20180126633A (ko) * 2007-09-26 2018-11-27 추가이 세이야쿠 가부시키가이샤 항체 정상영역 개변체
US10604561B2 (en) 2016-09-16 2020-03-31 Chugai Seiyaku Kabushiki Kaisha Anti-dengue virus antibodies, polypeptides containing variant Fc regions, and methods of use
US11891432B2 (en) 2018-03-15 2024-02-06 Chugai Seiyaku Kabushiki Kaisha Anti-dengue virus antibodies having cross-reactivity to Zika virus and methods of use

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WO2007043641A1 (ja) * 2005-10-14 2007-04-19 Fukuoka University 膵島移植における移植膵島障害抑制剤
AR058135A1 (es) * 2005-10-21 2008-01-23 Chugai Pharmaceutical Co Ltd Agentes para el tratamiento de cardiopatias
AR057582A1 (es) * 2005-11-15 2007-12-05 Nat Hospital Organization Agentes para suprimir la induccion de linfocitos t citotoxicos
AU2007208678B2 (en) * 2006-01-27 2013-01-10 Chugai Seiyaku Kabushiki Kaisha Therapeutic agents for diseases involving choroidal neovascularization
EP2009101B1 (en) 2006-03-31 2017-10-25 Chugai Seiyaku Kabushiki Kaisha Antibody modification method for purifying bispecific antibody
CN104761637B (zh) 2006-03-31 2021-10-15 中外制药株式会社 调控抗体血液动力学的方法
JP5754875B2 (ja) * 2006-04-07 2015-07-29 国立大学法人大阪大学 筋再生促進剤
ES2429407T3 (es) 2006-06-08 2013-11-14 Chugai Seiyaku Kabushiki Kaisha Agente preventivo o remedio para enfermedades inflamatorias
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TW201634479A (zh) 2007-12-05 2016-10-01 中外製藥股份有限公司 抗ｎｒ１０抗體及其應用
KR102057826B1 (ko) 2008-04-11 2019-12-20 추가이 세이야쿠 가부시키가이샤 복수 분자의 항원에 반복 결합하는 항원 결합 분자
WO2009131702A2 (en) 2008-04-25 2009-10-29 Dyax Corp. Antibodies against fcrn and use thereof
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