|
US9963510B2
(en)
|
2005-04-15 |
2018-05-08 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
DK1879573T3
(da)
|
2005-05-10 |
2013-02-25 |
Incyte Corp |
Modulatorer af indolamin 2,3-dioxygenase og fremgangsmåder til anvendelse deraf
|
|
CA3012229C
(en)
|
2008-07-08 |
2020-11-10 |
Incyte Holdings Corporation |
1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
CA2876689C
(en)
|
2012-06-13 |
2022-04-26 |
Incyte Corporation |
Substituted tricyclic compounds as fgfr inhibitors
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
KR102391731B1
(ko)
|
2013-01-14 |
2022-04-27 |
젠코어 인코포레이티드 |
신규한 이형이량체 단백질
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
PH12015502383B1
(en)
|
2013-04-19 |
2023-02-03 |
Incyte Holdings Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
PL3122781T3
(pl)
|
2014-03-28 |
2020-06-15 |
Xencor, Inc. |
Dwuswoiste przeciwciała, które wiążą się z CD38 i CD3
|
|
US10647768B2
(en)
*
|
2014-05-29 |
2020-05-12 |
Macrogenics, Inc. |
Multi-chain polypeptide-containing tri-specific binding molecules
|
|
TWI693232B
(zh)
*
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
HK1245171A1
(zh)
|
2014-11-26 |
2018-08-24 |
Xencor, Inc. |
结合cd3和cd38的异二聚体抗体
|
|
JP6696982B2
(ja)
|
2014-11-26 |
2020-05-20 |
ゼンコー・インコーポレイテッドＸｅｎｃｏｒ、 Ｉｎｃ． |
Ｃｄ３および腫瘍抗原に結合するヘテロ二量体抗体
|
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
|
CA2976790C
(en)
|
2015-02-20 |
2024-02-27 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
SMT202100467T1
(it)
|
2015-04-17 |
2021-09-14 |
Alpine Immune Sciences Inc |
Proteine immunomodulatorie con affinità regolabili
|
|
TWI773646B
(zh)
*
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
|
TWI870335B
(zh)
*
|
2015-06-12 |
2025-01-21 |
美商宏觀基因股份有限公司 |
變異的嵌合4d5抗體及其與抗pd-1抗體聯合用於治療癌症的應用
|
|
MX383464B
(es)
|
2015-07-13 |
2025-03-14 |
Cytomx Therapeutics Inc |
Anticuerpos anti-pd-1, anticuerpos anti-pd-1 activables, y métodos de uso de los mismos.
|
|
PE20231958A1
(es)
|
2015-07-30 |
2023-12-06 |
Macrogenics Inc |
Moleculas de union a pd-1 y metodos de uso de las mismas
|
|
JP6869987B2
(ja)
|
2015-09-01 |
2021-05-12 |
アジェナス インコーポレイテッド |
抗ｐｄ−１抗体及びその使用方法
|
|
BR112018006237A2
(pt)
|
2015-09-29 |
2018-10-09 |
Celgene Corp |
proteínas de ligação a pd-1 e métodos de uso das mesmas
|
|
CA3001131A1
(en)
|
2015-11-02 |
2017-05-11 |
Five Prime Therapeutics, Inc. |
Cd80 extracellular domain polypeptides and their use in cancer treatment
|
|
PT3370768T
(pt)
|
2015-11-03 |
2022-04-21 |
Janssen Biotech Inc |
Anticorpos que se ligam especificamente ao pd-1 e seus usos
|
|
EP3387013B1
(en)
|
2015-12-07 |
2022-06-08 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and psma
|
|
CN108367069B
(zh)
|
2015-12-14 |
2022-08-23 |
宏观基因有限公司 |
对于pd-1和ctla-4具有免疫反应性的双特异性分子及其使用方法
|
|
TWI828027B
(zh)
|
2016-03-28 |
2024-01-01 |
美商英塞特公司 |
作為tam抑制劑之吡咯并三嗪化合物
|
|
SG11201808457PA
(en)
|
2016-04-15 |
2018-10-30 |
Alpine Immune Sciences Inc |
Icos ligand variant immunomodulatory proteins and uses thereof
|
|
AU2017248830B2
(en)
|
2016-04-15 |
2023-03-09 |
Alpine Immune Sciences, Inc. |
CD80 variant immunomodulatory proteins and uses thereof
|
|
CA3026151A1
(en)
|
2016-06-14 |
2017-12-21 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
|
SG11201811184UA
(en)
|
2016-06-20 |
2019-01-30 |
F Star Beta Ltd |
Lag -3 binding members
|
|
KR102379464B1
(ko)
|
2016-06-20 |
2022-03-29 |
키맵 리미티드 |
항-pd-l1 항체
|
|
RU2019102008A
(ru)
|
2016-06-28 |
2020-07-28 |
Ксенкор, Инк. |
Гетеродимерные антитела, которые связывают рецептор соматостатина 2-го типа
|
|
WO2018022945A1
(en)
|
2016-07-28 |
2018-02-01 |
Alpine Immune Sciences, Inc. |
Cd112 variant immunomodulatory proteins and uses thereof
|
|
EP3491013A1
(en)
|
2016-07-28 |
2019-06-05 |
Alpine Immune Sciences, Inc. |
Cd155 variant immunomodulatory proteins and uses thereof
|
|
US11471488B2
(en)
|
2016-07-28 |
2022-10-18 |
Alpine Immune Sciences, Inc. |
CD155 variant immunomodulatory proteins and uses thereof
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
EP3515944A4
(en)
|
2016-09-19 |
2020-05-06 |
Celgene Corporation |
METHOD FOR TREATING IMMUNE DISEASES USING PD-1 BINDING PROTEINS
|
|
EP3515943A4
(en)
|
2016-09-19 |
2020-05-06 |
Celgene Corporation |
METHODS OF TREATING VITILIGO WITH PD-1 BINDING PROTEINS
|
|
MX2019004327A
(es)
|
2016-10-14 |
2019-10-14 |
Xencor Inc |
Proteinas de fusion heterodimericas biespecificas que contienen proteinas de fusion fc il-15/il-15ra y fragmentos de anticuerpo pd-1.
|
|
CN110300599B
(zh)
|
2016-12-07 |
2024-07-02 |
艾吉纳斯公司 |
抗体和其使用方法
|
|
US11299530B2
(en)
|
2017-01-05 |
2022-04-12 |
Kahr Medical Ltd. |
SIRP alpha-CD70 fusion protein and methods of use thereof
|
|
DK3565579T3
(da)
|
2017-01-05 |
2023-09-04 |
Kahr Medical Ltd |
Pd1-41bbl-fusionsprotein og fremgangsmåder til anvendelse deraf
|
|
US11566060B2
(en)
|
2017-01-05 |
2023-01-31 |
Kahr Medical Ltd. |
PD1-CD70 fusion protein and methods of use thereof
|
|
ES2916217T3
(es)
|
2017-01-05 |
2022-06-29 |
Kahr Medical Ltd |
Una proteína de fusión SIRP1 ALPHA-41BBL y métodos de uso de la misma
|
|
EP3565842A1
(en)
|
2017-01-06 |
2019-11-13 |
Crescendo Biologics Limited |
Single domain antibodies to programmed cell death (pd-1)
|
|
ES2902670T3
(es)
*
|
2017-01-13 |
2022-03-29 |
Taizhou Hanzhong Biopharmaceutics Inc |
Anticuerpo monoclonal contra PD-1 y aplicaciones del mismo
|
|
JP7275030B2
(ja)
|
2017-01-20 |
2023-05-17 |
タユー ファシャ バイオテック メディカル グループ カンパニー， リミテッド |
抗ｐｄ－１抗体およびその使用
|
|
CN108341871A
(zh)
*
|
2017-01-24 |
2018-07-31 |
三生国健药业（上海）股份有限公司 |
抗pd-1单克隆抗体及其制备方法和应用
|
|
WO2018153340A1
(en)
*
|
2017-02-22 |
2018-08-30 |
I-Mab |
Anti-lag-3 antibodies and uses thereof
|
|
BR112019017628A2
(pt)
|
2017-02-24 |
2020-07-07 |
Macrogenics, Inc. |
molécula de ligação a cd137 x ta, composições farmacêuticas, uso da molécula de ligação a cd137 x ta, molécula de ligação a cd137, uso da molécula de ligação a cd137, molécula de ligação a her2/neu, uso da molécula de ligação a her2/neu, e uso de uma composição
|
|
KR20240144261A
(ko)
|
2017-02-28 |
2024-10-02 |
사노피 |
치료적 rna
|
|
JP2020511144A
(ja)
|
2017-03-16 |
2020-04-16 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
Ｐｄ−ｌ２バリアント免疫調節タンパク質及びその使用
|
|
MX2019010887A
(es)
|
2017-03-16 |
2019-10-15 |
Alpine Immune Sciences Inc |
Proteinas inmunomoduladoras de cb80 variante y usos de estas.
|
|
EP3601355A1
(en)
|
2017-03-31 |
2020-02-05 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
BR112019021520A2
(pt)
|
2017-04-14 |
2020-08-04 |
Tollnine, Inc. |
oligonucleotídeo, composto, polinucleotídeo imunomodulador, composição, conjugado, método para modular um receptor, método de tratamento de um tumor, método de tratamento de câncer, método para tratar um tumor, método de prevenção de câncer, método para induzir uma resposta imune
|
|
JOP20190248A1
(ar)
|
2017-04-21 |
2019-10-20 |
Amgen Inc |
بروتينات ربط مولد ضد trem2 واستخداماته
|
|
CN110546509A
(zh)
|
2017-04-28 |
2019-12-06 |
戊瑞治疗有限公司 |
用cd80细胞外结构域多肽进行治疗的方法
|
|
US20200079850A1
(en)
*
|
2017-05-24 |
2020-03-12 |
Sutro Biopharma, Inc. |
Pd-1/lag3 bi-specific antibodies, compositions thereof, and methods of making and using the same
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
JP2020522495A
(ja)
|
2017-05-30 |
2020-07-30 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
抗ｌａｇ−３抗体、ｐｄ−１経路阻害剤および免疫療法剤の組み合わせを含む組成物
|
|
WO2018222718A1
(en)
|
2017-05-30 |
2018-12-06 |
Bristol-Myers Squibb Company |
Treatment of lag-3 positive tumors
|
|
JP7301002B2
(ja)
|
2017-05-30 |
2023-06-30 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗ｌａｇ－３抗体または抗ｌａｇ－３抗体および抗ｐｄ－１もしくは抗ｐｄ－ｌ１抗体を含む組成物
|
|
EP3630840A1
(en)
|
2017-06-01 |
2020-04-08 |
Bristol-Myers Squibb Company |
Methods of treating a tumor using an anti-pd-1 antibody
|
|
US10995149B2
(en)
|
2017-06-05 |
2021-05-04 |
Janssen Biotech, Inc. |
Antibodies that specifically bind PD-1 and methods of use
|
|
CN110799537B
(zh)
*
|
2017-06-25 |
2023-07-28 |
西雅图免疫公司 |
抗pd-1抗体及其制备和使用方法
|
|
KR20200037250A
(ko)
*
|
2017-07-06 |
2020-04-08 |
메뤼스 엔.페. |
세포에 의해 발현되는 생물학적 활성을 조절하는 항체
|
|
CN118126157A
(zh)
|
2017-08-03 |
2024-06-04 |
美国安进公司 |
白介素-21突变蛋白和治疗方法
|
|
KR20250020679A
(ko)
|
2017-08-04 |
2025-02-11 |
젠맵 에이/에스 |
Pd-l1 및 cd137에 결합하는 결합제 및 그의 용도
|
|
SG11202000387YA
(en)
|
2017-08-25 |
2020-03-30 |
Five Prime Therapeutics Inc |
B7-h4 antibodies and methods of use thereof
|
|
US10633387B2
(en)
|
2017-09-27 |
2020-04-28 |
Incyte Corporation |
Salts of TAM inhibitors
|
|
EP3694870A1
(en)
|
2017-10-10 |
2020-08-19 |
Alpine Immune Sciences, Inc. |
Ctla-4 variant immunomodulatory proteins and uses thereof
|
|
EP3694884A1
(en)
|
2017-10-15 |
2020-08-19 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
JP7282760B2
(ja)
|
2017-10-18 |
2023-05-29 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
バリアントｉｃｏｓリガンド免疫調節タンパク質ならびに関連する組成物および方法
|
|
KR20200084880A
(ko)
|
2017-11-06 |
2020-07-13 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
AU2018366199A1
(en)
|
2017-11-08 |
2020-05-28 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
CA3082297A1
(en)
|
2017-11-13 |
2019-05-16 |
Crescendo Biologics Limited |
Molecules that bind to cd137 and psma
|
|
CN109897111B
(zh)
*
|
2017-12-08 |
2021-02-23 |
杭州翰思生物医药有限公司 |
抗pd-1/cd47的双特异性抗体及其应用
|
|
JP7765181B2
(ja)
|
2017-12-19 |
2025-11-06 |
ゼンコア インコーポレイテッド |
改変されたｉｌ－２ ｆｃ融合タンパク質
|
|
CN109971712B
(zh)
*
|
2017-12-28 |
2023-06-20 |
上海细胞治疗研究院 |
特异性靶向cd19抗原且高水平稳定表达pd-1抗体的car-t细胞及用途
|
|
CN109971714B
(zh)
*
|
2017-12-28 |
2023-06-20 |
上海细胞治疗研究院 |
自表达pd-1抗体并靶向间皮素的嵌合抗原受体修饰t细胞及其用途
|
|
SG11202006148UA
(en)
|
2018-01-03 |
2020-07-29 |
Alpine Immune Sciences Inc |
Multi-domain immunomodulatory proteins and methods of use thereof
|
|
MX2020007291A
(es)
|
2018-01-12 |
2020-09-10 |
Amgen Inc |
Anticuerpos anti-pd-1 y metodos de tratamiento.
|
|
AU2019210332A1
(en)
|
2018-01-22 |
2020-09-10 |
Pascal Biosciences Inc. |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
WO2019148410A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1 antibodies
|
|
WO2019148412A1
(en)
*
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1/lag3 bispecific antibodies
|
|
GB201802573D0
(en)
*
|
2018-02-16 |
2018-04-04 |
Crescendo Biologics Ltd |
Therapeutic molecules that bind to LAG3
|
|
WO2019165077A1
(en)
|
2018-02-21 |
2019-08-29 |
Five Prime Therapeutics, Inc. |
B7-h4 antibody formulations
|
|
CN112105642B
(zh)
|
2018-02-23 |
2023-01-31 |
祐和医药科技(北京)有限公司 |
抗pd-1抗体及其用途
|
|
AU2019227607C1
(en)
|
2018-02-27 |
2023-07-20 |
Incyte Corporation |
Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors
|
|
KR20200144094A
(ko)
|
2018-03-02 |
2020-12-28 |
파이브 프라임 테라퓨틱스, 인크. |
B7-h4 항체 및 이의 사용 방법
|
|
US20210115138A1
(en)
*
|
2018-03-20 |
2021-04-22 |
WuXi Biologics Ireland Limited |
Novel bispecific pd-1/lag-3 antibody molecules
|
|
TWI841554B
(zh)
|
2018-03-21 |
2024-05-11 |
丹麥商珍美寶股份有限公司 |
以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法
|
|
JP7351845B2
(ja)
|
2018-03-23 |
2023-09-27 |
ブリストル－マイヤーズ スクイブ カンパニー |
Ｍｉｃａおよび／またはｍｉｃｂに対する抗体ならびにそれらの使用
|
|
CN108546297B
(zh)
*
|
2018-03-29 |
2019-08-02 |
中国人民解放军军事科学院军事医学研究院 |
针对pd-1的单克隆抗体及其应用
|
|
EP3774911A1
(en)
|
2018-03-30 |
2021-02-17 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
CN112469477A
(zh)
|
2018-04-04 |
2021-03-09 |
Xencor股份有限公司 |
与成纤维细胞活化蛋白结合的异源二聚体抗体
|
|
WO2019195621A1
(en)
*
|
2018-04-04 |
2019-10-10 |
Immutics, Inc. |
Methods and compositions for blocking interaction between non-glycosylated pd-1 polypeptides
|
|
JP2021520850A
(ja)
*
|
2018-04-15 |
2021-08-26 |
サルブリス （チョンドゥ） バイオテック カンパニー リミテッド |
Ｐｄ−１結合抗体及びその使用
|
|
KR20210003814A
(ko)
|
2018-04-18 |
2021-01-12 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα Fc-융합 단백질 및 TIM-3 항원 결합 도메인을 함유하는 TIM-3 표적화 이종이량체 융합 단백질
|
|
CA3097593A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
CN112074541A
(zh)
*
|
2018-05-03 |
2020-12-11 |
上海岸迈生物科技有限公司 |
Pd-1和lag-3的高亲和力抗体以及由其制备的双特异性结合蛋白
|
|
KR102956194B1
(ko)
|
2018-05-04 |
2026-04-23 |
인사이트 코포레이션 |
Fgfr 억제제의 염
|
|
RS66310B1
(sr)
|
2018-05-04 |
2025-01-31 |
Incyte Corp |
Čvrsti oblici inhibitora fgfr i procesi za njegovu pripremu
|
|
EA202092136A1
(ru)
|
2018-05-07 |
2021-03-22 |
Генмаб А/С |
Способы лечения рака с помощью комбинации антитела к pd-1 и конъюгата антитела к тканевому фактору и лекарственного средства
|
|
JP7460608B2
(ja)
|
2018-05-07 |
2024-04-02 |
ジェンマブ エー／エス |
抗ｐｄ－１抗体と抗組織因子抗体－薬物コンジュゲートとの組み合わせを用いるがんの治療方法
|
|
EP3810610A1
(en)
|
2018-05-18 |
2021-04-28 |
Incyte Corporation |
Fused pyrimidine derivatives as a2a / a2b inhibitors
|
|
WO2019227490A1
(en)
|
2018-06-01 |
2019-12-05 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
Compositions and methods for imaging
|
|
JP2021525806A
(ja)
|
2018-06-01 |
2021-09-27 |
タユー ファシャ バイオテック メディカル グループ カンパニー， リミテッド |
疾患または状態を処置するための組成物およびそれらの使用
|
|
KR20210030366A
(ko)
*
|
2018-06-20 |
2021-03-17 |
인사이트 코포레이션 |
항-pd-1 항체 및 이의 용도
|
|
ES3031110T3
(en)
|
2018-06-29 |
2025-07-04 |
Incyte Corp |
Formulations of an axl/mer inhibitor
|
|
CN117304191A
(zh)
|
2018-07-05 |
2023-12-29 |
因赛特公司 |
作为a2a/a2b抑制剂的稠合吡嗪衍生物
|
|
CN110684113A
(zh)
*
|
2018-07-06 |
2020-01-14 |
复旦大学 |
一种抗PD-1抗原和抗c-Met抗原的双特异性抗体及其构建方法
|
|
IL280102B1
(en)
|
2018-07-11 |
2026-07-01 |
Kahr Medical Ltd |
Fusion protein containing PD1-4-1BBL and methods of using the same
|
|
CA3104780A1
(en)
|
2018-07-11 |
2020-01-16 |
Kahr Medical Ltd. |
Sirpalpha-4-1bbl variant fusion protein and methods of use thereof
|
|
AU2019301206B2
(en)
|
2018-07-12 |
2025-10-30 |
Invox Pharma Limited |
Antibody molecules that bind CD137 and OX40
|
|
GB201811415D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-Mesothelin Anti bodies
|
|
GB201811410D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
OX40 Binding molecules
|
|
BR112021000394A2
(pt)
|
2018-07-12 |
2021-04-06 |
F-Star Beta Limited |
Moléculas de anticorpo que se ligam a pd-l1 e cd137
|
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
|
GB201811403D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Antibody molecules
|
|
GB201811404D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-CD137 Antibodies
|
|
GB201811450D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Delta Ltd |
Mesothelin and CD137 binding molecules
|
|
EP3823991A4
(en)
*
|
2018-07-19 |
2022-08-03 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
ANTI-PD-1 ANTIBODIES, DOSAGE FORMS AND USES THEREOF
|
|
AU2019309849A1
(en)
|
2018-07-26 |
2021-03-18 |
Bristol-Myers Squibb Company |
LAG-3 combination therapy for the treatment of cancer
|
|
EP3852779A4
(en)
|
2018-09-17 |
2022-06-08 |
Abcuro, Inc. |
ANTI-KLRG1 ANTIBODIES
|
|
SG11202102851XA
(en)
|
2018-09-27 |
2021-04-29 |
Celgene Corp |
SIRPa BINDING PROTEINS AND METHODS OF USE THEREOF
|
|
KR102884523B1
(ko)
|
2018-10-03 |
2025-11-10 |
젠코어 인코포레이티드 |
IL-12 이종이량체 Fc-융합 단백질
|
|
US11066404B2
(en)
|
2018-10-11 |
2021-07-20 |
Incyte Corporation |
Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
|
|
AU2019361923B2
(en)
|
2018-10-15 |
2026-07-09 |
Five Prime Therapeutics, Inc. |
Combination therapy for cancer
|
|
WO2020081928A1
(en)
|
2018-10-19 |
2020-04-23 |
Bristol-Myers Squibb Company |
Combination therapy for melanoma
|
|
JP2022505647A
(ja)
|
2018-10-23 |
2022-01-14 |
ブリストル－マイヤーズ スクイブ カンパニー |
腫瘍の処置方法
|
|
TWI844571B
(zh)
|
2018-10-30 |
2024-06-11 |
丹麥商珍美寶股份有限公司 |
使用抗血管內皮生長因子（ｖｅｇｆ）抗體與抗組織因子（ｔｆ）抗體－藥物共軛體之組合以治療癌症之方法
|
|
EP3880247A4
(en)
|
2018-11-13 |
2022-10-26 |
JN Biosciences, LLC |
Bispecific antibodies for activation of immune cells
|
|
MX2021005708A
(es)
|
2018-11-16 |
2021-09-21 |
Bristol Myers Squibb Co |
Anticuerpos anti grupo 2a del receptor inhibidor de células asesinas naturales (anti-nkg2a) y usos de los mismos.
|
|
CN113727998A
(zh)
|
2018-11-30 |
2021-11-30 |
高山免疫科学股份有限公司 |
Cd86变体免疫调节蛋白及其用途
|
|
US20220099637A1
(en)
|
2018-12-04 |
2022-03-31 |
Bristol-Myers Squibb Company |
Methods of analysis using in-sample calibration curve by multiple isotopologue reaction monitoring
|
|
EP3666905A1
(en)
|
2018-12-11 |
2020-06-17 |
Sanofi |
E. coli positive for pks island as marker of positive response to anti-pd1 therapy in colorectal cancer
|
|
US20220056135A1
(en)
|
2018-12-21 |
2022-02-24 |
Ose Immunotherapeutics |
Bifunctional anti-pd-1/sirpa molecule
|
|
WO2020127377A1
(en)
|
2018-12-21 |
2020-06-25 |
Ose Immunotherapeutics |
Bifunctional anti-pd-1/il-7 molecule
|
|
CN111349162A
(zh)
*
|
2018-12-21 |
2020-06-30 |
神州细胞工程有限公司 |
人源化抗pd-1抗体及其用途
|
|
CN111423510B
(zh)
*
|
2019-01-10 |
2024-02-06 |
迈威(上海)生物科技股份有限公司 |
重组抗人pd-1抗体及其应用
|
|
AU2020210614A1
(en)
|
2019-01-21 |
2021-08-26 |
Sanofi |
Therapeutic RNA and anti-PD1 antibodies for advanced stage solid tumor cancers
|
|
CN113795511B
(zh)
*
|
2019-01-23 |
2024-07-23 |
大有华夏生物医药集团有限公司 |
抗pd-l1双抗体及其用途
|
|
TWI829857B
(zh)
|
2019-01-29 |
2024-01-21 |
美商英塞特公司 |
作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
|
|
MX2021009041A
(es)
*
|
2019-02-03 |
2021-08-19 |
Jiangsu Hengrui Medicine Co |
Anticuerpo anti-pd-1, fragmento de union a antigeno del mismo y uso farmaceutico del mismo.
|
|
WO2020165374A1
(en)
|
2019-02-14 |
2020-08-20 |
Ose Immunotherapeutics |
Bifunctional molecule comprising il-15ra
|
|
EA202192260A1
(ru)
|
2019-02-15 |
2021-12-17 |
Инсайт Корпорейшн |
Биомаркеры циклин-зависимой киназы 2 и их применение
|
|
WO2020168197A1
(en)
|
2019-02-15 |
2020-08-20 |
Incyte Corporation |
Pyrrolo[2,3-d]pyrimidinone compounds as cdk2 inhibitors
|
|
AU2020224137B2
(en)
|
2019-02-22 |
2026-01-08 |
Five Prime Therapeutics, Inc. |
CD80 extracellular domain-Fc fusion proteins for treating PD-L1 negative tumors
|
|
EP3930850A1
(en)
|
2019-03-01 |
2022-01-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
|
TW202100520A
(zh)
|
2019-03-05 |
2021-01-01 |
美商英塞特公司 |
作為cdk2 抑制劑之吡唑基嘧啶基胺化合物
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
KR20210146348A
(ko)
|
2019-03-28 |
2021-12-03 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
WO2020198676A1
(en)
|
2019-03-28 |
2020-10-01 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
US11919904B2
(en)
|
2019-03-29 |
2024-03-05 |
Incyte Corporation |
Sulfonylamide compounds as CDK2 inhibitors
|
|
WO2020223558A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
Tricyclic amine compounds as cdk2 inhibitors
|
|
WO2020223469A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer
|
|
MX2021013272A
(es)
|
2019-05-03 |
2021-11-17 |
Five Prime Therapeutics Inc |
Formulaciones farmaceuticas que contienen proteinas de fusion fc de dominio extracelular de cd80.
|
|
US20220241412A1
(en)
|
2019-05-24 |
2022-08-04 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
|
JP2022534982A
(ja)
|
2019-05-30 |
2022-08-04 |
ブリストル－マイヤーズ スクイブ カンパニー |
細胞局在化シグネチャーおよびその使用
|
|
US20220363760A1
(en)
|
2019-05-30 |
2022-11-17 |
Bristol-Myers Squibb Company |
Multi-tumor gene signature for suitability to immuno-oncology therapy
|
|
WO2020243570A1
(en)
|
2019-05-30 |
2020-12-03 |
Bristol-Myers Squibb Company |
Cell localization signature and combination therapy
|
|
CN112225809B
(zh)
*
|
2019-06-30 |
2023-09-05 |
福州创方医药科技有限公司 |
一种靶向pd-1的单克隆抗体及其应用
|
|
CN117447596A
(zh)
*
|
2019-06-30 |
2024-01-26 |
福州创方医药科技有限公司 |
一种靶向pd-1的单克隆抗体及其应用
|
|
JP6881658B2
(ja)
|
2019-07-05 |
2021-06-02 |
小野薬品工業株式会社 |
Ｐｄ−１／ｃｄ３二重特異性タンパク質による血液がん治療
|
|
WO2021007269A1
(en)
|
2019-07-09 |
2021-01-14 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2021005546A1
(en)
|
2019-07-09 |
2021-01-14 |
Cadila Healthcare Limited |
Antibodies to human programmed death receptor pd-1
|
|
CN112239506B
(zh)
*
|
2019-07-16 |
2023-09-26 |
复旦大学 |
一种抗PD-1及c-Met抗原的小分子双特异性抗体Diabody
|
|
WO2021022172A1
(en)
|
2019-08-01 |
2021-02-04 |
Incyte Corporation |
A dosing regimen for an ido inhibitor
|
|
BR112022002028A2
(pt)
*
|
2019-08-02 |
2022-04-12 |
Cttq Akeso Shanghai Biomed Tech Co Ltd |
Anticorpo anti-pd-1 e uso farmacêutico do mesmo
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
WO2021025140A1
(ja)
|
2019-08-08 |
2021-02-11 |
小野薬品工業株式会社 |
二重特異性タンパク質
|
|
WO2021030537A1
(en)
|
2019-08-14 |
2021-02-18 |
Incyte Corporation |
Imidazolyl pyrimidinylamine compounds as cdk2 inhibitors
|
|
WO2021055994A1
(en)
|
2019-09-22 |
2021-03-25 |
Bristol-Myers Squibb Company |
Quantitative spatial profiling for lag-3 antagonist therapy
|
|
CN114728070A
(zh)
|
2019-09-25 |
2022-07-08 |
百时美施贵宝公司 |
用于癌症疗法的复合生物标记物
|
|
CN114206931B
(zh)
*
|
2019-09-30 |
2024-06-04 |
四川科伦博泰生物医药股份有限公司 |
抗pd-1抗体及其用途
|
|
US12122767B2
(en)
|
2019-10-01 |
2024-10-22 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
CR20220170A
(es)
|
2019-10-11 |
2022-10-10 |
Incyte Corp |
Aminas bicíclicas como inhibidoras de la cdk2
|
|
GEP20247679B
(en)
|
2019-10-14 |
2024-10-10 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021092044A1
(en)
|
2019-11-05 |
2021-05-14 |
Bristol-Myers Squibb Company |
M-protein assays and uses thereof
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
EP4054723A1
(en)
|
2019-11-08 |
2022-09-14 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for melanoma
|
|
WO2021097256A1
(en)
|
2019-11-14 |
2021-05-20 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
|
WO2021097800A1
(en)
*
|
2019-11-22 |
2021-05-27 |
Abl Bio Inc. |
Anti-pd-l1/anti-b7-h3 multispecific antibodies and uses thereof
|
|
MX2022006691A
(es)
|
2019-12-04 |
2022-09-19 |
Incyte Corp |
Derivados de un inhibidor de receptores del factor de crecimiento de fibroblastos (fgfr).
|
|
WO2021113479A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
TW202136287A
(zh)
|
2019-12-17 |
2021-10-01 |
法商Ｏｓｅ免疫治療公司 |
包含il-7變體之雙官能分子
|
|
WO2021127554A1
(en)
|
2019-12-19 |
2021-06-24 |
Bristol-Myers Squibb Company |
Combinations of dgk inhibitors and checkpoint antagonists
|
|
EP4079763A4
(en)
*
|
2019-12-20 |
2023-10-11 |
Guangdong Feipeng Pharmaceutical Co., Ltd |
MONOCLONAL ANTIBODY AGAINST HUMAN PROGRAMMED DEATH-1 (PD-1)
|
|
KR20220119694A
(ko)
*
|
2019-12-23 |
2022-08-30 |
마크로제닉스, 인크. |
암 치료를 위한 요법
|
|
CN115279766B
(zh)
*
|
2020-01-03 |
2025-05-02 |
因赛特公司 |
包含a2a/a2b和pd-1/pd-l1抑制剂的组合疗法
|
|
MX2022008412A
(es)
|
2020-01-07 |
2022-08-08 |
Univ Texas |
Variantes de enzima que agotan metiltioadenosina/adenosina mejorada humana para terapia de cancer.
|
|
WO2021146749A1
(en)
|
2020-01-13 |
2021-07-22 |
The University Of Chicago |
Toll-like receptor agonist formulations and methods of use
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
US20230090446A1
(en)
|
2020-01-28 |
2023-03-23 |
Universite De Strasbourg |
Antisense oligonucleotide targeting linc00518 for treating melanoma
|
|
KR20220132555A
(ko)
|
2020-01-29 |
2022-09-30 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
Nrg1 융합체를 사용한 암 치료를 위한 egfr/her2 티로신 키나제 억제제 및/또는 her2/her3 항체의 사용
|
|
KR20220133238A
(ko)
|
2020-01-29 |
2022-10-04 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
Nrg1 융합체가 있는 암의 치료를 위한 포지오티닙의 용도
|
|
AU2021213969A1
(en)
|
2020-01-30 |
2022-09-01 |
ONA Therapeutics S.L. |
Combination therapy for treatment of cancer and cancer metastasis
|
|
WO2021158938A1
(en)
|
2020-02-06 |
2021-08-12 |
Bristol-Myers Squibb Company |
Il-10 and uses thereof
|
|
JP7745556B2
(ja)
|
2020-02-21 |
2025-09-29 |
マクロジェニクス，インコーポレーテッド |
Ｃｄ１３７結合分子及びその使用
|
|
IL295759A
(en)
|
2020-02-28 |
2022-10-01 |
Tallac Therapeutics Inc |
Transglutaminase mediated coupling
|
|
WO2021170082A1
(zh)
*
|
2020-02-28 |
2021-09-02 |
南京圣和药业股份有限公司 |
抗cd47/抗pd-l1抗体及其应用
|
|
PH12022552347A1
(en)
|
2020-03-06 |
2024-01-29 |
Incyte Corp |
Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors
|
|
WO2021176424A1
(en)
|
2020-03-06 |
2021-09-10 |
Ona Therapeutics, S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
|
BR112022017637A2
(pt)
|
2020-03-06 |
2022-11-08 |
Celgene Quanticel Res Inc |
Métodos de tratamento do câncer de pulmão de células pequenas e/ou câncer de pulmão de células não pequenas
|
|
CN121270550A
(zh)
|
2020-04-16 |
2026-01-06 |
因赛特公司 |
稠合三环kras抑制剂
|
|
WO2021219048A1
(zh)
*
|
2020-04-30 |
2021-11-04 |
迈威(上海)生物科技股份有限公司 |
一种靶向nkg2a和pd-l1的双特异性抗体及应用
|
|
EP4147053B1
(en)
|
2020-05-07 |
2026-01-28 |
Institut Curie |
Antxr1 as a biomarker of immunosuppressive fibroblast populations and its use for predicting response to immunotherapy
|
|
US12202882B2
(en)
|
2020-05-08 |
2025-01-21 |
Alpine Immune Sciences, Inc. |
APRIL and BAFF inhibitory immunomodulatory proteins and methods of use thereof
|
|
WO2021231526A1
(en)
|
2020-05-13 |
2021-11-18 |
Incyte Corporation |
Fused pyrimidine compounds as kras inhibitors
|
|
EP4149632A1
(en)
|
2020-05-14 |
2023-03-22 |
Xencor, Inc. |
Heterodimeric antibodies that bind msln and cd3
|
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
|
CN116234568A
(zh)
|
2020-07-07 |
2023-06-06 |
生物技术公司 |
用于hpv阳性癌症的治疗性rna
|
|
KR20230042038A
(ko)
*
|
2020-07-27 |
2023-03-27 |
마크로제닉스, 인크. |
PD-1 x CTLA-4 이중특이적 분자의 사용 방법
|
|
US11919958B2
(en)
|
2020-08-19 |
2024-03-05 |
Xencor, Inc. |
Anti-CD28 compositions
|
|
JP2023538367A
(ja)
*
|
2020-08-19 |
2023-09-07 |
パンディオン・オペレーションズ・インコーポレイテッド |
マルチパラトピック抗ｐｄ－１抗体およびその用途
|
|
WO2022047093A1
(en)
|
2020-08-28 |
2022-03-03 |
Incyte Corporation |
Vinyl imidazole compounds as inhibitors of kras
|
|
MX2023002332A
(es)
|
2020-08-28 |
2023-03-21 |
Bristol Myers Squibb Co |
Terapia con antagonistas del gen 3 de activacion de linfocitos (lag-3) para carcinoma hepatocelular.
|
|
IL300916A
(en)
|
2020-08-31 |
2023-04-01 |
Bristol Myers Squibb Co |
Cell localization signature and immunotherapy
|
|
WO2022072783A1
(en)
|
2020-10-02 |
2022-04-07 |
Incyte Corporation |
Bicyclic dione compounds as inhibitors of kras
|
|
JP2023544410A
(ja)
|
2020-10-05 |
2023-10-23 |
ブリストル－マイヤーズ スクイブ カンパニー |
タンパク質を濃縮するための方法
|
|
WO2022076596A1
(en)
|
2020-10-06 |
2022-04-14 |
Codiak Biosciences, Inc. |
Extracellular vesicle-aso constructs targeting stat6
|
|
US12555649B2
(en)
|
2020-10-09 |
2026-02-17 |
Worldwide Innovative Network |
Prediction method and gene signatures for the treatment of cancer
|
|
CA3196496A1
(en)
|
2020-10-23 |
2022-04-28 |
Laurence David TOMS |
Lag-3 antagonist therapy for lung cancer
|
|
CA3196535A1
(en)
|
2020-10-28 |
2022-05-05 |
Alfredo C. Castro |
Combination of an ahr inhibitor with a pdx inhibitor or doxorubicine
|
|
MX2023005528A
(es)
|
2020-11-17 |
2023-06-23 |
Seagen Inc |
Metodos de tratamiento del cancer con una combinacion de tucatinib y un anticuerpo anti-pd-1/anti-pd-l1.
|
|
WO2022112198A1
(en)
|
2020-11-24 |
2022-06-02 |
Worldwide Innovative Network |
Method to select the optimal immune checkpoint therapies
|
|
US20220168293A1
(en)
|
2020-12-02 |
2022-06-02 |
Pfizer Inc. |
Time to resolution of axitinib-related adverse events
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
US20250270320A1
(en)
*
|
2020-12-10 |
2025-08-28 |
Eutilex Co., Ltd. |
Anti-pd-1 antibody and uses thereof
|
|
AU2021402065A1
(en)
|
2020-12-17 |
2023-06-29 |
Boehringer Ingelheim International Gmbh |
Bifunctional anti-pd1/il-7 molecules
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性ｒｎａ
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
AU2021416156A1
(en)
|
2020-12-28 |
2023-06-22 |
Bristol-Myers Squibb Company |
Methods of treating tumors
|
|
PT4267105T
(pt)
|
2020-12-28 |
2025-04-30 |
Bristol Myers Squibb Co |
Composições de anticorpos e métodos de utilização das mesmas
|
|
JP2024502005A
(ja)
|
2020-12-29 |
2024-01-17 |
インサイト・コーポレイション |
Ａ２ａ／ａ２ｂ阻害剤、ｐｄ－１／ｐｄ－ｌ１阻害剤、及び抗ｃｄ７３抗体を含む併用療法
|
|
WO2022148781A1
(en)
|
2021-01-05 |
2022-07-14 |
Institut Curie |
Combination of mcoln activators and immune checkpoint inhibitors
|
|
CN117321079A
(zh)
*
|
2021-01-11 |
2023-12-29 |
优特力克斯有限公司 |
包含抗4-1bb抗体及pd-1蛋白或其片段的双特异性表位结合蛋白及其用途
|
|
EP4284950A4
(en)
|
2021-01-29 |
2024-12-25 |
Board of Regents, The University of Texas System |
METHODS OF TREATMENT OF CANCER USING KINASE INHIBITORS
|
|
CN113336848B
(zh)
*
|
2021-02-03 |
2022-08-19 |
上海莱馥医疗科技有限公司 |
一种抗pd-1抗体及其用途
|
|
EP4305067A1
(en)
|
2021-03-09 |
2024-01-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
|
US11859012B2
(en)
|
2021-03-10 |
2024-01-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and GPC3
|
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
|
CN117858719A
(zh)
|
2021-03-29 |
2024-04-09 |
朱诺治疗学股份有限公司 |
使用检查点抑制剂疗法和car t细胞疗法的组合进行给药和治疗的方法
|
|
JP2024514530A
(ja)
|
2021-04-02 |
2024-04-02 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
切断型ｃｄｃｐ１に対する抗体およびその使用
|
|
EP4319755A4
(en)
|
2021-04-08 |
2025-03-26 |
Board of Regents, The University of Texas System |
Compounds and methods for theranostic targeting of parp activity
|
|
MX2023011964A
(es)
|
2021-04-09 |
2024-01-08 |
Ose Immunotherapeutics |
Nuevo andamio para moléculas bifuncionales con propiedades mejoradas.
|
|
EP4320156A1
(en)
|
2021-04-09 |
2024-02-14 |
Ose Immunotherapeutics |
Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
|
|
EP4323405A1
(en)
|
2021-04-12 |
2024-02-21 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
|
US20240285740A1
(en)
|
2021-05-12 |
2024-08-29 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating cancer
|
|
GB202107994D0
(en)
|
2021-06-04 |
2021-07-21 |
Kymab Ltd |
Treatment of cancer
|
|
TW202313610A
(zh)
|
2021-06-09 |
2023-04-01 |
美商英塞特公司 |
作為ｆｇｆｒ抑制劑之三環雜環
|
|
CA3220274A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
US11981671B2
(en)
|
2021-06-21 |
2024-05-14 |
Incyte Corporation |
Bicyclic pyrazolyl amines as CDK2 inhibitors
|
|
WO2023283213A1
(en)
|
2021-07-07 |
2023-01-12 |
Incyte Corporation |
Tricyclic compounds as inhibitors of kras
|
|
CA3224640A1
(en)
*
|
2021-07-09 |
2023-01-12 |
Krishnan SAMPATHKUMAR |
Pharmaceutical compositions of a pd-1 antibody and use of the same
|
|
WO2023285552A1
(en)
|
2021-07-13 |
2023-01-19 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
|
CA3224841A1
(en)
|
2021-07-14 |
2023-01-19 |
Zhenwu Li |
Tricyclic compounds as inhibitors of kras
|
|
CA3226281A1
(en)
|
2021-07-30 |
2023-02-02 |
ONA Therapeutics S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
|
CA3229855A1
(en)
|
2021-08-31 |
2023-03-09 |
Incyte Corporation |
Naphthyridine compounds as inhibitors of kras
|
|
US12030883B2
(en)
|
2021-09-21 |
2024-07-09 |
Incyte Corporation |
Hetero-tricyclic compounds as inhibitors of KRAS
|
|
US20250084155A1
(en)
|
2021-09-29 |
2025-03-13 |
Board Of Regents, The University Of Texas System |
Anti-hsp70 antibodies and therapeutic uses thereof
|
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
BioNTech SE |
Treatment involving non-immunogenic rna for antigen vaccination and pd-1 axis binding antagonists
|
|
US12030884B2
(en)
|
2021-10-01 |
2024-07-09 |
Incyte Corporation |
Pyrazoloquinoline KRAS inhibitors
|
|
TW202327595A
(zh)
|
2021-10-05 |
2023-07-16 |
美商輝瑞大藥廠 |
用於治療癌症之氮雜內醯胺化合物的組合
|
|
WO2023057534A1
(en)
|
2021-10-06 |
2023-04-13 |
Genmab A/S |
Multispecific binding agents against pd-l1 and cd137 in combination
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
KR20240101561A
(ko)
|
2021-10-14 |
2024-07-02 |
인사이트 코포레이션 |
Kras의 저해제로서의 퀴놀린 화합물
|
|
WO2023070100A1
(en)
*
|
2021-10-21 |
2023-04-27 |
Seismic Therapeutic, Inc. |
Dual targeted immune regulating compositions
|
|
WO2023077090A1
(en)
|
2021-10-29 |
2023-05-04 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hematological cancer
|
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
|
WO2023083439A1
(en)
|
2021-11-09 |
2023-05-19 |
BioNTech SE |
Tlr7 agonist and combinations for cancer treatment
|
|
MX2024006113A
(es)
|
2021-11-22 |
2024-07-29 |
Incyte Corp |
Terapia de combinación que comprende un inhibidor del receptor del factor de crecimiento de fibroblastos (fgfr) y un inhibidor del sarcoma de rata de kirsten (kras).
|
|
US11976073B2
(en)
|
2021-12-10 |
2024-05-07 |
Incyte Corporation |
Bicyclic amines as CDK2 inhibitors
|
|
CR20240297A
(es)
|
2021-12-22 |
2024-09-18 |
Incyte Corp |
Sales y formas sólidas de un inhibidor de fgfr y procesos para su preparación
|
|
AU2023213937A1
(en)
|
2022-01-26 |
2024-07-18 |
Bristol-Myers Squibb Company |
Combination therapy for hepatocellular carcinoma
|
|
KR20240153583A
(ko)
|
2022-02-25 |
2024-10-23 |
브리스톨-마이어스 스큅 컴퍼니 |
결장직장암종에 대한 병용 요법
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
CN119156403A
(zh)
|
2022-03-08 |
2024-12-17 |
阿伦蒂斯治疗股份公司 |
抗紧密连接蛋白-1抗体增加t细胞可用性的用途
|
|
US20250206775A1
(en)
|
2022-03-18 |
2025-06-26 |
Bristol-Myers Squibb Company |
Methods of isolating polypeptides
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
JP7851417B2
(ja)
|
2022-04-08 |
2026-04-24 |
ブリストル－マイヤーズ スクイブ カンパニー |
三次リンパ組織様構造の機械学習識別、分類、及び定量化
|
|
CA3253038A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
LIAISON AGENTS CAPABLE OF BINDING TO CD27 IN POLYTHERAPY
|
|
AU2023281061A1
(en)
|
2022-06-02 |
2024-12-05 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
TW202417479A
(zh)
*
|
2022-06-07 |
2024-05-01 |
美商英塞特公司 |
用於治療癌症之抗-pd-1活性劑、抗-tim-3活性劑及抗-lag-3活性劑之組合療法
|
|
CN119998295A
(zh)
|
2022-06-08 |
2025-05-13 |
因赛特公司 |
作为dgk抑制剂的三环三唑并化合物
|
|
WO2024003360A1
(en)
|
2022-07-01 |
2024-01-04 |
Institut Curie |
Biomarkers and uses thereof for the treatment of neuroblastoma
|
|
US20240101557A1
(en)
|
2022-07-11 |
2024-03-28 |
Incyte Corporation |
Fused tricyclic compounds as inhibitors of kras g12v mutants
|
|
US12600722B2
(en)
|
2022-07-18 |
2026-04-14 |
Incyte Corporation |
Tetracyclic compounds as DGK inhibitors
|
|
US12600723B2
(en)
|
2022-07-18 |
2026-04-14 |
Incyte Corporation |
Tetracyclic compounds as DGK inhibitors
|
|
EP4310197A1
(en)
|
2022-07-21 |
2024-01-24 |
Fundación para la Investigación Biomédica del Hospital Universitario Puerta de Hierro Majadahonda |
Method for identifying lung cancer patients for a combination treatment of immuno- and chemotherapy
|
|
AU2023313118A1
(en)
|
2022-07-27 |
2025-03-06 |
Astrazeneca Ab |
Combinations of recombinant virus expressing interleukin-12 with pd-1/pd-l1 inhibitors
|
|
EP4565610A1
(en)
|
2022-08-02 |
2025-06-11 |
Ose Immunotherapeutics |
Multifunctional molecule directed against cd28
|
|
US20240101718A1
(en)
*
|
2022-09-28 |
2024-03-28 |
Incyte Corporation |
Anti-pd-1/lag-3 bispecific antibodies and uses thereof
|
|
CN120379691A
(zh)
|
2022-09-30 |
2025-07-25 |
爱兰蒂斯疗法股份公司 |
耐药性肝细胞癌的治疗
|
|
EP4608858A2
(en)
*
|
2022-10-25 |
2025-09-03 |
The Brigham & Women's Hospital, Inc. |
Klrb1 binding agents and methods of use thereof
|
|
US12030945B2
(en)
|
2022-10-25 |
2024-07-09 |
Seismic Therapeutic, Inc. |
Variant IgG Fc polypeptides and uses thereof
|
|
WO2024097328A1
(en)
|
2022-11-03 |
2024-05-10 |
Incyte Corporation |
Combination therapies comprising an anti-gitr antibody for treating cancers
|
|
WO2024107731A2
(en)
*
|
2022-11-14 |
2024-05-23 |
Ablexis, Llc |
Anti-pd-l1 antibodies
|
|
WO2024105180A1
(en)
|
2022-11-16 |
2024-05-23 |
Boehringer Ingelheim International Gmbh |
Predictive efficacy biomarkers for anti-sirpa antibodies
|
|
US20240217989A1
(en)
|
2022-11-18 |
2024-07-04 |
Incyte Corporation |
Heteroaryl Fluoroalkenes As DGK Inhibitors
|
|
CN120302979A
(zh)
|
2022-12-01 |
2025-07-11 |
生物技术公司 |
针对CD40和CD137的多特异性抗体与抗PD1 Ab和化学治疗的组合治疗
|
|
AU2023403103A1
(en)
|
2022-12-01 |
2025-07-10 |
Medimmune Limited |
Combination therapy for treatment of cancer comprising anti-pd-l1 and anti-cd73 antibodies
|
|
JP2026501506A
(ja)
|
2022-12-14 |
2026-01-16 |
アステラス・ファーマ・ヨーロッパ・ベスローデン・フェンノートシャップ |
Ｃｌｄｎ１８．２及びｃｄ３に結合する二重特異性結合剤並びに免疫チェックポイント阻害剤を含む併用療法
|
|
KR20250123912A
(ko)
|
2022-12-21 |
2025-08-18 |
브리스톨-마이어스 스큅 컴퍼니 |
폐암에 대한 병용 요법
|
|
CN117482246B
(zh)
*
|
2022-12-30 |
2024-10-15 |
英百瑞(杭州)生物医药有限公司 |
抗cd33/cll1双特异性抗体-自然杀伤细胞偶联物及其用途
|
|
KR20240112755A
(ko)
*
|
2023-01-11 |
2024-07-19 |
주식회사 녹십자 |
혈전성 질환의 예방 또는 치료를 위한 신규한 액상 제형물
|
|
WO2024150177A1
(en)
|
2023-01-11 |
2024-07-18 |
Advesya |
Treatment methods for solid tumors
|
|
TW202428575A
(zh)
|
2023-01-12 |
2024-07-16 |
美商英塞特公司 |
作為ｄｇｋ抑制劑之雜芳基氟代烯烴
|
|
US20240294651A1
(en)
|
2023-01-30 |
2024-09-05 |
Kymab Limited |
Antibodies
|
|
JP2026506893A
(ja)
|
2023-02-23 |
2026-02-27 |
イムチェック セラピューティクス エスエーエス |
Ｂｔｎ３ａ活性化抗体と免役チェックポイント阻害剤の併用
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024200820A1
(en)
|
2023-03-30 |
2024-10-03 |
Ose Immunotherapeutics |
Method of synthesis of targeted lipid nanoparticle and uses thereof
|
|
JP2026512425A
(ja)
|
2023-03-30 |
2026-04-16 |
オーエスイー・イミュノセラピューティクス |
免疫細胞増強分子の発現のための活性化免疫細胞に標的化された脂質ベースのナノ粒子及びその使用
|
|
EP4688160A1
(en)
|
2023-04-06 |
2026-02-11 |
Genmab A/S |
Multispecific binding agents against pd-l1 and cd137 for treating cancer
|
|
US20240390340A1
(en)
|
2023-04-18 |
2024-11-28 |
Incyte Corporation |
Pyrrolidine kras inhibitors
|
|
IL324457A
(en)
|
2023-05-12 |
2026-01-01 |
Genmab As |
Antibodies capable of binding to ox40, their variants and uses thereof
|
|
WO2024236048A1
(en)
|
2023-05-16 |
2024-11-21 |
Nh Theraguix |
Combination therapy for treating tumors with radiotherapy
|
|
WO2024261239A1
(en)
|
2023-06-23 |
2024-12-26 |
Imcheck Therapeutics |
Bispecific antibodies targeting btn3a and the pd-1/pd-l1 inhibitory axis
|
|
CN121712571A
(zh)
|
2023-08-15 |
2026-03-20 |
百时美施贵宝公司 |
陶瓷羟基磷灰石色谱流通法
|
|
US20250066363A1
(en)
|
2023-08-24 |
2025-02-27 |
Incyte Corporation |
Bicyclic DGK Inhibitors
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
WO2025068461A1
(en)
|
2023-09-29 |
2025-04-03 |
Negio Therapeutics |
Guanfacine derivatives and their use in treating cancer
|
|
WO2025068452A1
(en)
|
2023-09-29 |
2025-04-03 |
Negio Therapeutics |
Guanfacine derivatives and their use in treating cancer
|
|
US20250114346A1
(en)
|
2023-10-09 |
2025-04-10 |
Incyte Corporation |
Combination therapy using a kras g12d inhibitor and pd-1 inhibitor or pd-l1 inhibitor
|
|
US20250163079A1
(en)
|
2023-11-01 |
2025-05-22 |
Incyte Corporation |
Kras inhibitors
|
|
CN122580346A
(zh)
|
2023-11-21 |
2026-08-14 |
布里格姆妇女医院 |
Klrb1结合剂及其使用方法
|
|
CN122249464A
(zh)
|
2023-11-30 |
2026-06-19 |
金麦安博股份有限公司 |
在组合疗法中的能够结合ox40的抗体
|
|
TW202523667A
(zh)
|
2023-12-05 |
2025-06-16 |
美商英塞特公司 |
作為ｄｇｋ抑制劑之三環三唑并化合物
|
|
US20250186450A1
(en)
|
2023-12-06 |
2025-06-12 |
Incyte Corporation |
COMBINATION THERAPY COMPRISING DGK INHIBITORS and PD-1/PD-L1 INHIBITORS
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2026033885A1
(en)
|
2024-08-08 |
2026-02-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
AR134560A1
(es)
|
2023-12-08 |
2026-01-28 |
Astellas Pharma Inc |
Terapia de combinación que implica agentes de unión biespecíficos que se unen a cldn18.2 y cd3 y agentes que estabilizan o aumentan la expresión de cldn18.2
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025129002A1
(en)
|
2023-12-13 |
2025-06-19 |
Incyte Corporation |
Bicyclooctane kras inhibitors
|
|
WO2025132831A1
(en)
|
2023-12-19 |
2025-06-26 |
Universite D'aix-Marseille |
N-heteroaryl derivatives and uses thereof for treating cancer
|
|
WO2025133115A1
(en)
|
2023-12-21 |
2025-06-26 |
Ose Immunotherapeutics |
Lipid-based nanoparticles comprising il-35
|
|
CN122459678A
(zh)
|
2023-12-29 |
2026-07-24 |
百时美施贵宝公司 |
KRAS抑制剂与Treg耗竭剂的组合疗法
|
|
US20250361320A1
(en)
|
2024-02-27 |
2025-11-27 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
US12521446B2
(en)
|
2024-02-27 |
2026-01-13 |
Bristol-Myers Squibb Company |
Anti-CEACAM5 antibody drug conjugates
|
|
WO2025242835A1
(en)
|
2024-05-22 |
2025-11-27 |
Ose Immunotherapeutics |
Molecules comprising masking linkers and uses thereof for the treatment of cancer
|
|
WO2025245489A1
(en)
|
2024-05-24 |
2025-11-27 |
Bristol-Myers Squibb Company |
Treatment of tumors in subjects having fgl-1 positive samples
|
|
WO2025262250A1
(en)
|
2024-06-20 |
2025-12-26 |
Negio Therapeutics |
Guanfacine derivatives and their uses
|
|
WO2026060143A1
(en)
|
2024-09-11 |
2026-03-19 |
Incyte Corporation |
Kras inhibitors
|
|
WO2026068705A1
(en)
|
2024-09-26 |
2026-04-02 |
Ose Immunotherapeutics |
Lipid-based nanoparticles comprising non-glycosylated fc domains and uses thereof
|
|
WO2026093414A1
(en)
|
2024-10-30 |
2026-05-07 |
Ose Immunotherapeutics |
Lipid-based nanoparticles comprising membrane il-35
|
|
WO2026096695A1
(en)
|
2024-10-31 |
2026-05-07 |
Bristol-Myers Squibb Company |
Anti-fucosyl-gm1 antibody drug conjugates
|
|
WO2026107031A1
(en)
|
2024-11-13 |
2026-05-21 |
Incyte Corporation |
Kras inhibitors
|
|
WO2026109006A1
(zh)
*
|
2024-11-21 |
2026-05-28 |
广东菲鹏制药股份有限公司 |
Pd-l1结合分子及其应用
|
|
US20260144885A1
(en)
|
2024-11-22 |
2026-05-28 |
Bristol-Myers Squibb Company |
Anti-lrrc15 antibodies and uses thereof
|
|
US20260144884A1
(en)
|
2024-11-22 |
2026-05-28 |
Bristol-Myers Squibb Company |
Anti-lrrc15 antibody drug conjugates
|
|
WO2026133192A1
(en)
|
2024-12-20 |
2026-06-25 |
Pfizer Inc. |
Combination therapies using cdk4 inhibitors with pd-1 axis binding antagonists
|
|
CN122277738A
(zh)
*
|
2026-05-25 |
2026-06-26 |
星锐医药(苏州)有限公司 |
靶向pd-1的抑制或耗竭抗体及其用途
|