JP2021524249A5 - - Google Patents
Info
- Publication number
- JP2021524249A5 JP2021524249A5 JP2020565282A JP2020565282A JP2021524249A5 JP 2021524249 A5 JP2021524249 A5 JP 2021524249A5 JP 2020565282 A JP2020565282 A JP 2020565282A JP 2020565282 A JP2020565282 A JP 2020565282A JP 2021524249 A5 JP2021524249 A5 JP 2021524249A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- antibody
- binding fragment
- seq
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024087232A JP2024116190A (ja) | 2018-05-24 | 2024-05-29 | 抗cd3抗体及びその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862676081P | 2018-05-24 | 2018-05-24 | |
| US62/676,081 | 2018-05-24 | ||
| PCT/IB2019/054188 WO2019224717A2 (en) | 2018-05-24 | 2019-05-21 | Anti-cd3 antibodies and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024087232A Division JP2024116190A (ja) | 2018-05-24 | 2024-05-29 | 抗cd3抗体及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021524249A JP2021524249A (ja) | 2021-09-13 |
| JP2021524249A5 true JP2021524249A5 (enExample) | 2022-05-25 |
| JP7530299B2 JP7530299B2 (ja) | 2024-08-07 |
Family
ID=67211773
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020565282A Active JP7530299B2 (ja) | 2018-05-24 | 2019-05-21 | 抗cd3抗体及びその使用 |
| JP2024087232A Withdrawn JP2024116190A (ja) | 2018-05-24 | 2024-05-29 | 抗cd3抗体及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024087232A Withdrawn JP2024116190A (ja) | 2018-05-24 | 2024-05-29 | 抗cd3抗体及びその使用 |
Country Status (38)
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL319047A (en) | 2015-08-28 | 2025-04-01 | Amunix Operating Inc | Chimeric polypeptide composition and methods for its preparation and use |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| WO2018231827A1 (en) | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| EA202092849A1 (ru) | 2018-05-24 | 2021-03-16 | Янссен Байотек, Инк. | Моноспецифические и мультиспецифические антитела к tmeff2 и их применение |
| JOP20190116A1 (ar) * | 2018-05-24 | 2019-11-24 | Janssen Biotech Inc | الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها |
| MX2020012598A (es) | 2018-05-24 | 2021-05-27 | Janssen Biotech Inc | Agentes aglutinantes del psma y usos de estos. |
| LT4324851T (lt) | 2018-07-19 | 2025-10-10 | Chimeriniai antigeno receptoriai, pasižymintys bcma specifiškumu, ir jų panaudojimas | |
| TWI838389B (zh) | 2018-07-19 | 2024-04-11 | 美商再生元醫藥公司 | 雙特異性抗-BCMAx抗-CD3抗體及其用途 |
| AR118720A1 (es) | 2019-04-19 | 2021-10-27 | Janssen Biotech Inc | Métodos para tratar el cáncer de próstata con un anticuerpo anti-psma / cd3 |
| JP7686571B2 (ja) | 2019-05-08 | 2025-06-02 | ヤンセン バイオテツク,インコーポレーテツド | T細胞媒介性免疫を調節するための材料及び方法 |
| CR20220025A (es) | 2019-07-26 | 2022-05-04 | Janssen Biotech Inc | Proteínas que comprenden dominios de unión al antígeno de la peptidasa 2 relacionada con la calicreína y sus usos |
| PH12022551470A1 (en) * | 2019-12-18 | 2023-05-03 | Janssen Biotech Inc | Materials and methods for in vivo biological targeting |
| CA3173268A1 (en) * | 2020-02-27 | 2021-09-02 | Janssen Biotech, Inc. | Materials and methods for modulating an immune response |
| US20210284731A1 (en) * | 2020-03-13 | 2021-09-16 | Janssen Biotech, Inc. | Methods and materials for modulating an immune response |
| KR20230008775A (ko) | 2020-05-08 | 2023-01-16 | 젠맵 에이/에스 | Cd3 및 cd20에 대한 이중특이적 항체 |
| PE20230389A1 (es) | 2020-05-27 | 2023-03-06 | Janssen Biotech Inc | Proteinas que comprenden dominios de union al antigeno de cd3 y usos de estas |
| JP7862361B2 (ja) | 2020-07-29 | 2026-05-19 | ヤンセン バイオテツク,インコーポレーテツド | Hla-g抗原結合ドメインを含むタンパク質及びそれらの使用 |
| JP2023539525A (ja) * | 2020-09-02 | 2023-09-14 | ジェンマブ エー/エス | 抗体療法 |
| AU2021345124A1 (en) | 2020-09-16 | 2023-03-30 | Amgen Inc. | Methods for administering therapeutic doses of bispecific T-cell engaging molecules for the treatment of cancer |
| WO2022068809A1 (zh) * | 2020-09-29 | 2022-04-07 | 信达生物制药(苏州)有限公司 | 抗cd3抗体以及其用途 |
| US20240025992A1 (en) | 2020-10-22 | 2024-01-25 | Janssen Biotech, Inc. | Proteins comprising delta-like ligand 3 (dll3) antigen binding domains and their uses |
| WO2022175255A2 (en) * | 2021-02-16 | 2022-08-25 | Janssen Pharmaceutica Nv | Trispecific antibody targeting bcma, gprc5d, and cd3 |
| MX2023013714A (es) | 2021-05-21 | 2024-01-16 | Leo Pharma As | Anticuerpos anti-proteina accesoria del receptor de interleucina 1 (il-1). |
| WO2023026235A1 (en) * | 2021-08-27 | 2023-03-02 | Janssen Biotech, Inc. | Anti-psma antibodies and uses thereof |
| US12600764B2 (en) | 2021-08-27 | 2026-04-14 | International Business Machines Corporation | Antigen-binding proteins targeting coronavirus (COV) variants |
| CN118974087A (zh) * | 2022-03-09 | 2024-11-15 | 德琪(杭州)生物有限公司 | 新颖的抗cd3抗体以及其用途 |
| WO2023178645A1 (zh) * | 2022-03-25 | 2023-09-28 | 嘉和生物药业有限公司 | 靶向cd3的抗体及其应用 |
| US12054552B2 (en) * | 2022-09-21 | 2024-08-06 | Sanofi Biotechnology | Humanized anti-IL-1R3 antibody and methods of use |
| EP4598958A1 (en) | 2022-10-05 | 2025-08-13 | Amgen Inc. | Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof |
| WO2024089551A1 (en) | 2022-10-25 | 2024-05-02 | Janssen Biotech, Inc. | Msln and cd3 binding agents and methods of use thereof |
| WO2024126833A1 (en) * | 2022-12-16 | 2024-06-20 | Ichnos Sciences SA | Cd47-il1rap bispecific antibodies |
| WO2025134050A1 (en) | 2023-12-21 | 2025-06-26 | Janssen Biotech, Inc | Trispecific antibody targeting bcma, gprc5d and cd3 for the treatment of multiple myeloma |
| WO2025134049A1 (en) | 2023-12-21 | 2025-06-26 | Janssen Biotech, Inc | Trispecific antibody targeting bcma, gprc5d and cd3 for the treatment of al amyloidosis |
| TW202602940A (zh) | 2024-04-09 | 2026-01-16 | 美商安進公司 | 激動性抗il-2rbg重鏈抗體 |
| WO2025230233A1 (ko) * | 2024-05-03 | 2025-11-06 | 국민대학교산학협력단 | 인간 cd3에 특이적인 항체 및 이의 용도 |
| WO2025259563A2 (en) * | 2024-06-10 | 2025-12-18 | Amberstone Biosciences, Inc. | Anti-cd3 constructs and uses thereof |
| WO2026006492A2 (en) | 2024-06-25 | 2026-01-02 | Ypsilon Therapeutics, Inc. | Anti-prame/hla-a2 antibodies and uses thereof |
| WO2026006495A1 (en) | 2024-06-25 | 2026-01-02 | Alloy Therapeutics, Inc. | Anti-wt1/hla-a2 antibody and uses thereof |
| WO2026078647A1 (en) | 2024-10-11 | 2026-04-16 | Janssen Biotech, Inc. | Combination of trispecific antibody targeting bcma, gprc5d and cd3, and pomalidomide for the treatment of multiple myeloma |
| US20260102490A1 (en) | 2024-10-11 | 2026-04-16 | Janssen Biotech, Inc. | Combination of trispecific antibody targeting bcma, gprc5d and cd3, and an anti-cd38 antibody for the treatment of multiple myeloma |
Family Cites Families (52)
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| ATE199392T1 (de) | 1992-12-04 | 2001-03-15 | Medical Res Council | Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung |
| AUPO591797A0 (en) | 1997-03-27 | 1997-04-24 | Commonwealth Scientific And Industrial Research Organisation | High avidity polyvalent and polyspecific reagents |
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| WO2007147901A1 (en) | 2006-06-22 | 2007-12-27 | Novo Nordisk A/S | Production of bispecific antibodies |
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| CR20220578A (es) | 2016-09-14 | 2023-01-17 | Teneobio Inc | Anticuerpos de unión a cd3 |
| WO2019220368A1 (en) * | 2018-05-16 | 2019-11-21 | Janssen Biotech, Inc. | Bcma/cd3 and gprdc5d/cd3 bispecific antibodies for use in cancer therapy |
| MX2020012598A (es) | 2018-05-24 | 2021-05-27 | Janssen Biotech Inc | Agentes aglutinantes del psma y usos de estos. |
| EA202092849A1 (ru) | 2018-05-24 | 2021-03-16 | Янссен Байотек, Инк. | Моноспецифические и мультиспецифические антитела к tmeff2 и их применение |
| JOP20190116A1 (ar) | 2018-05-24 | 2019-11-24 | Janssen Biotech Inc | الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها |
-
2019
- 2019-05-21 BR BR112020023508-3A patent/BR112020023508A2/pt unknown
- 2019-05-21 RS RS20250579A patent/RS66901B1/sr unknown
- 2019-05-21 CN CN202510209510.8A patent/CN120058941A/zh active Pending
- 2019-05-21 UA UAA202008271A patent/UA129050C2/uk unknown
- 2019-05-21 JO JOP/2020/0302A patent/JOP20200302A1/ar unknown
- 2019-05-21 DK DK19737219.6T patent/DK3802608T3/da active
- 2019-05-21 WO PCT/IB2019/054188 patent/WO2019224717A2/en not_active Ceased
- 2019-05-21 ES ES19737219T patent/ES3032856T3/es active Active
- 2019-05-21 PE PE2020001886A patent/PE20210132A1/es unknown
- 2019-05-21 SM SM20250221T patent/SMT202500221T1/it unknown
- 2019-05-21 FI FIEP19737219.6T patent/FI3802608T3/fi active
- 2019-05-21 EA EA202092847A patent/EA202092847A1/ru unknown
- 2019-05-21 CR CR20200568A patent/CR20200568A/es unknown
- 2019-05-21 MX MX2020012587A patent/MX420253B/es unknown
- 2019-05-21 US US16/418,082 patent/US11603405B2/en active Active
- 2019-05-21 HR HRP20250621TT patent/HRP20250621T1/hr unknown
- 2019-05-21 PL PL19737219.6T patent/PL3802608T3/pl unknown
- 2019-05-21 CN CN201980049271.7A patent/CN112912397B/zh active Active
- 2019-05-21 LT LTEPPCT/IB2019/054188T patent/LT3802608T/lt unknown
- 2019-05-21 PT PT197372196T patent/PT3802608T/pt unknown
- 2019-05-21 SG SG11202011270QA patent/SG11202011270QA/en unknown
- 2019-05-21 EP EP19737219.6A patent/EP3802608B1/en active Active
- 2019-05-21 CA CA3101271A patent/CA3101271A1/en active Pending
- 2019-05-21 AU AU2019274656A patent/AU2019274656B2/en active Active
- 2019-05-21 JP JP2020565282A patent/JP7530299B2/ja active Active
- 2019-05-21 HU HUE19737219A patent/HUE072251T2/hu unknown
- 2019-05-21 KR KR1020207037046A patent/KR20210012007A/ko active Pending
- 2019-05-21 EP EP25173398.6A patent/EP4643951A3/en active Pending
- 2019-05-21 SI SI201930938T patent/SI3802608T1/sl unknown
- 2019-05-21 MA MA52773A patent/MA52773B1/fr unknown
- 2019-05-24 UY UY0001038245A patent/UY38245A/es unknown
- 2019-05-24 AR ARP190101400A patent/AR115422A1/es unknown
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2020
- 2020-11-09 PH PH12020551920A patent/PH12020551920A1/en unknown
- 2020-11-19 IL IL278846A patent/IL278846A/en unknown
- 2020-11-23 NI NI202000089A patent/NI202000089A/es unknown
- 2020-11-23 CL CL2020003033A patent/CL2020003033A1/es unknown
- 2020-11-23 EC ECSENADI202075215A patent/ECSP20075215A/es unknown
- 2020-11-23 CO CONC2020/0014506A patent/CO2020014506A2/es unknown
- 2020-11-24 SA SA520420631A patent/SA520420631B1/ar unknown
- 2020-12-18 ZA ZA2020/07936A patent/ZA202007936B/en unknown
-
2023
- 2023-03-08 US US18/180,225 patent/US20230322924A1/en active Granted
-
2024
- 2024-05-29 JP JP2024087232A patent/JP2024116190A/ja not_active Withdrawn
-
2026
- 2026-06-18 AU AU2026204725A patent/AU2026204725A1/en active Pending
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