SG11202011270QA - Anti-cd3 antibodies and uses thereof - Google Patents
Anti-cd3 antibodies and uses thereofInfo
- Publication number
- SG11202011270QA SG11202011270QA SG11202011270QA SG11202011270QA SG11202011270QA SG 11202011270Q A SG11202011270Q A SG 11202011270QA SG 11202011270Q A SG11202011270Q A SG 11202011270QA SG 11202011270Q A SG11202011270Q A SG 11202011270QA SG 11202011270Q A SG11202011270Q A SG 11202011270QA
- Authority
- SG
- Singapore
- Prior art keywords
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862676081P | 2018-05-24 | 2018-05-24 | |
PCT/IB2019/054188 WO2019224717A2 (en) | 2018-05-24 | 2019-05-21 | Anti-cd3 antibodies and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202011270QA true SG11202011270QA (en) | 2020-12-30 |
Family
ID=67211773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202011270QA SG11202011270QA (en) | 2018-05-24 | 2019-05-21 | Anti-cd3 antibodies and uses thereof |
Country Status (25)
Country | Link |
---|---|
US (2) | US11603405B2 (en) |
EP (1) | EP3802608A2 (en) |
JP (1) | JP2021524249A (en) |
KR (1) | KR20210012007A (en) |
CN (1) | CN112912397A (en) |
AR (1) | AR115422A1 (en) |
AU (1) | AU2019274656A1 (en) |
BR (1) | BR112020023508A2 (en) |
CA (1) | CA3101271A1 (en) |
CL (1) | CL2020003033A1 (en) |
CO (1) | CO2020014506A2 (en) |
CR (1) | CR20200568A (en) |
EA (1) | EA202092847A1 (en) |
EC (1) | ECSP20075215A (en) |
IL (1) | IL278846A (en) |
JO (1) | JOP20200302A1 (en) |
MA (1) | MA52773A (en) |
MX (1) | MX2020012587A (en) |
NI (1) | NI202000089A (en) |
PE (1) | PE20210132A1 (en) |
PH (1) | PH12020551920A1 (en) |
SG (1) | SG11202011270QA (en) |
TW (1) | TW202012443A (en) |
UY (1) | UY38245A (en) |
WO (1) | WO2019224717A2 (en) |
Families Citing this family (16)
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WO2017040344A2 (en) | 2015-08-28 | 2017-03-09 | Amunix Operating Inc. | Chimeric polypeptide assembly and methods of making and using the same |
CN110997725A (en) | 2017-06-12 | 2020-04-10 | 蓝鳍生物医药公司 | anti-IL 1RAP antibodies and antibody drug conjugates |
BR112020023416A2 (en) | 2018-05-24 | 2021-02-17 | Janssen Biotech, Inc. | monospecific and multispecific anti-tmeff2 antibodies and their uses |
JOP20190116A1 (en) * | 2018-05-24 | 2019-11-24 | Janssen Biotech Inc | Anti-cd33 antibodies, anti-cd33/anti-cd3 bispecific antibodies and uses thereof |
KR20210015902A (en) | 2018-05-24 | 2021-02-10 | 얀센 바이오테크 인코포레이티드 | PSMA binders and uses thereof |
BR112021000186A2 (en) * | 2018-07-19 | 2021-08-10 | Regeneron Pharmaceuticals, Inc. | bispecific anti-bcma x anti-cd3 antibodies and their uses |
MX2021012767A (en) | 2019-04-19 | 2021-11-18 | Janssen Biotech Inc | Methods of treating prostate cancer with an anti- psma/cd3 antibody. |
KR20220040483A (en) * | 2019-07-26 | 2022-03-30 | 얀센 바이오테크 인코포레이티드 | Proteins comprising kallikrein-associated peptidase 2 antigen binding domains and uses thereof |
US20220411504A1 (en) * | 2020-05-27 | 2022-12-29 | Janssen Biotech, Inc. | Proteins comprising cd3 antigen binding domains and uses thereof |
AR123083A1 (en) | 2020-07-29 | 2022-10-26 | Janssen Biotech Inc | PROTEINS INCLUDING HLA-G ANTIGEN BINDING DOMAINS AND THEIR USES |
US20230398147A1 (en) | 2020-09-16 | 2023-12-14 | Amgen Inc. | Methods for administering therapeutic doses of bispecific t-cell engaging molecules for the treatment of cancer |
US20240025992A1 (en) | 2020-10-22 | 2024-01-25 | Janssen Biotech, Inc. | Proteins comprising delta-like ligand 3 (dll3) antigen binding domains and their uses |
US20230073821A1 (en) * | 2021-08-27 | 2023-03-09 | International Business Machines Corporation | Antigen-binding proteins targeting coronavirus (cov) variants |
WO2023178645A1 (en) * | 2022-03-25 | 2023-09-28 | 嘉和生物药业有限公司 | Cd3-targeting antibody and use thereof |
US20240101691A1 (en) * | 2022-09-21 | 2024-03-28 | Sanofi Biotechnology | Humanized anti-il-1r3 antibody and methods of use |
WO2024077044A1 (en) | 2022-10-05 | 2024-04-11 | Amgen Inc. | Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof |
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BR112020023416A2 (en) | 2018-05-24 | 2021-02-17 | Janssen Biotech, Inc. | monospecific and multispecific anti-tmeff2 antibodies and their uses |
JOP20190116A1 (en) | 2018-05-24 | 2019-11-24 | Janssen Biotech Inc | Anti-cd33 antibodies, anti-cd33/anti-cd3 bispecific antibodies and uses thereof |
KR20210015902A (en) | 2018-05-24 | 2021-02-10 | 얀센 바이오테크 인코포레이티드 | PSMA binders and uses thereof |
-
2019
- 2019-05-21 SG SG11202011270QA patent/SG11202011270QA/en unknown
- 2019-05-21 US US16/418,082 patent/US11603405B2/en active Active
- 2019-05-21 JO JOP/2020/0302A patent/JOP20200302A1/en unknown
- 2019-05-21 PE PE2020001886A patent/PE20210132A1/en unknown
- 2019-05-21 CR CR20200568A patent/CR20200568A/en unknown
- 2019-05-21 MA MA052773A patent/MA52773A/en unknown
- 2019-05-21 EA EA202092847A patent/EA202092847A1/en unknown
- 2019-05-21 EP EP19737219.6A patent/EP3802608A2/en active Pending
- 2019-05-21 MX MX2020012587A patent/MX2020012587A/en unknown
- 2019-05-21 CN CN201980049271.7A patent/CN112912397A/en active Pending
- 2019-05-21 WO PCT/IB2019/054188 patent/WO2019224717A2/en unknown
- 2019-05-21 JP JP2020565282A patent/JP2021524249A/en active Pending
- 2019-05-21 AU AU2019274656A patent/AU2019274656A1/en active Pending
- 2019-05-21 BR BR112020023508-3A patent/BR112020023508A2/en unknown
- 2019-05-21 CA CA3101271A patent/CA3101271A1/en active Pending
- 2019-05-21 KR KR1020207037046A patent/KR20210012007A/en unknown
- 2019-05-24 AR ARP190101400A patent/AR115422A1/en unknown
- 2019-05-24 UY UY0001038245A patent/UY38245A/en unknown
- 2019-05-24 TW TW108118086A patent/TW202012443A/en unknown
-
2020
- 2020-11-09 PH PH12020551920A patent/PH12020551920A1/en unknown
- 2020-11-19 IL IL278846A patent/IL278846A/en unknown
- 2020-11-23 CL CL2020003033A patent/CL2020003033A1/en unknown
- 2020-11-23 EC ECSENADI202075215A patent/ECSP20075215A/en unknown
- 2020-11-23 NI NI202000089A patent/NI202000089A/en unknown
- 2020-11-23 CO CONC2020/0014506A patent/CO2020014506A2/en unknown
-
2023
- 2023-03-08 US US18/180,225 patent/US20230322924A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3802608A2 (en) | 2021-04-14 |
AU2019274656A1 (en) | 2020-11-26 |
TW202012443A (en) | 2020-04-01 |
MX2020012587A (en) | 2021-04-28 |
WO2019224717A2 (en) | 2019-11-28 |
MA52773A (en) | 2021-04-14 |
KR20210012007A (en) | 2021-02-02 |
PE20210132A1 (en) | 2021-01-19 |
JOP20200302A1 (en) | 2020-11-23 |
CR20200568A (en) | 2021-02-26 |
NI202000089A (en) | 2021-01-21 |
WO2019224717A3 (en) | 2020-03-05 |
WO2019224717A9 (en) | 2021-02-04 |
US11603405B2 (en) | 2023-03-14 |
CA3101271A1 (en) | 2019-11-28 |
CO2020014506A2 (en) | 2020-12-10 |
US20230322924A1 (en) | 2023-10-12 |
US20200048349A1 (en) | 2020-02-13 |
CN112912397A (en) | 2021-06-04 |
JP2021524249A (en) | 2021-09-13 |
CL2020003033A1 (en) | 2021-04-16 |
AR115422A1 (en) | 2021-01-20 |
UY38245A (en) | 2019-11-29 |
IL278846A (en) | 2021-01-31 |
BR112020023508A2 (en) | 2021-03-30 |
ECSP20075215A (en) | 2020-12-31 |
PH12020551920A1 (en) | 2021-06-14 |
EA202092847A1 (en) | 2021-04-20 |
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