JP2021524255A5 - - Google Patents
Info
- Publication number
- JP2021524255A5 JP2021524255A5 JP2020565399A JP2020565399A JP2021524255A5 JP 2021524255 A5 JP2021524255 A5 JP 2021524255A5 JP 2020565399 A JP2020565399 A JP 2020565399A JP 2020565399 A JP2020565399 A JP 2020565399A JP 2021524255 A5 JP2021524255 A5 JP 2021524255A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- tmeff2
- antigen
- binding fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024076617A JP2024105476A (ja) | 2018-05-24 | 2024-05-09 | 単一特異性及び二重特異性抗体抗-tmeff2抗体並びにそれらの使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862675957P | 2018-05-24 | 2018-05-24 | |
| US62/675,957 | 2018-05-24 | ||
| PCT/IB2019/054184 WO2019224713A2 (en) | 2018-05-24 | 2019-05-21 | Monospecific and multispecific anti-tmeff2 antibodies and there uses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024076617A Division JP2024105476A (ja) | 2018-05-24 | 2024-05-09 | 単一特異性及び二重特異性抗体抗-tmeff2抗体並びにそれらの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021524255A JP2021524255A (ja) | 2021-09-13 |
| JP2021524255A5 true JP2021524255A5 (enExample) | 2022-05-25 |
Family
ID=67211771
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020565399A Pending JP2021524255A (ja) | 2018-05-24 | 2019-05-21 | 単一特異性及び二重特異性抗体抗−tmeff2抗体並びにそれらの使用 |
| JP2024076617A Pending JP2024105476A (ja) | 2018-05-24 | 2024-05-09 | 単一特異性及び二重特異性抗体抗-tmeff2抗体並びにそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024076617A Pending JP2024105476A (ja) | 2018-05-24 | 2024-05-09 | 単一特異性及び二重特異性抗体抗-tmeff2抗体並びにそれらの使用 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US11866499B2 (enExample) |
| EP (1) | EP3802607A2 (enExample) |
| JP (2) | JP2021524255A (enExample) |
| KR (1) | KR20210011999A (enExample) |
| CN (1) | CN112703203B (enExample) |
| AR (1) | AR115419A1 (enExample) |
| AU (1) | AU2019274652B2 (enExample) |
| BR (1) | BR112020023416A2 (enExample) |
| CA (1) | CA3101304A1 (enExample) |
| CL (1) | CL2020003032A1 (enExample) |
| CO (1) | CO2020014515A2 (enExample) |
| CR (1) | CR20200564A (enExample) |
| EA (1) | EA202092849A1 (enExample) |
| EC (1) | ECSP20075234A (enExample) |
| IL (1) | IL278862A (enExample) |
| JO (1) | JOP20200295A1 (enExample) |
| MA (1) | MA52772A (enExample) |
| MX (1) | MX2020012589A (enExample) |
| NI (1) | NI202000087A (enExample) |
| PE (1) | PE20210634A1 (enExample) |
| PH (1) | PH12020551948A1 (enExample) |
| SG (1) | SG11202011268VA (enExample) |
| TW (1) | TWI865451B (enExample) |
| UY (1) | UY38243A (enExample) |
| WO (1) | WO2019224713A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020023508A2 (pt) * | 2018-05-24 | 2021-03-30 | Janssen Biotech, Inc. | Anticorpos anti-cd3 e usos dos mesmos |
| PH12022551470A1 (en) * | 2019-12-18 | 2023-05-03 | Janssen Biotech Inc | Materials and methods for in vivo biological targeting |
| PE20230389A1 (es) | 2020-05-27 | 2023-03-06 | Janssen Biotech Inc | Proteinas que comprenden dominios de union al antigeno de cd3 y usos de estas |
| US20230374140A1 (en) * | 2020-10-09 | 2023-11-23 | Memorial Sloan Kettering Cancer Center | Compositions targeting ndc80/mhc complexes and uses thereof |
| KR20230086765A (ko) | 2020-10-13 | 2023-06-15 | 얀센 바이오테크 인코포레이티드 | 분화 클러스터 iv 및/또는 viii을 조절하기 위한 바이오-조작된 t 세포 매개 면역, 물질 및 기타 방법 |
| WO2022175255A2 (en) | 2021-02-16 | 2022-08-25 | Janssen Pharmaceutica Nv | Trispecific antibody targeting bcma, gprc5d, and cd3 |
| IL314993A (en) | 2022-02-23 | 2024-10-01 | Xencor Inc | Anti-cd28 x anti-psma antibodies |
| EP4583980A1 (en) * | 2022-09-09 | 2025-07-16 | Janssen Biotech, Inc. | Method of treating cancer with an anti tmeff2xcd3 bispecific antibody |
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| US226A (en) | 1837-06-03 | Samuel goss | ||
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| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
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| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
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| US6255458B1 (en) | 1990-08-29 | 2001-07-03 | Genpharm International | High affinity human antibodies and human antibodies against digoxin |
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| PT1024191E (pt) | 1991-12-02 | 2008-12-22 | Medical Res Council | Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos |
| ATE199392T1 (de) | 1992-12-04 | 2001-03-15 | Medical Res Council | Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung |
| AUPO591797A0 (en) | 1997-03-27 | 1997-04-24 | Commonwealth Scientific And Industrial Research Organisation | High avidity polyvalent and polyspecific reagents |
| EP0983303B1 (en) | 1997-05-21 | 2006-03-08 | Biovation Limited | Method for the production of non-immunogenic proteins |
| US6818749B1 (en) | 1998-10-31 | 2004-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Variants of humanized anti carcinoma monoclonal antibody cc49 |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| DE60131456T2 (de) | 2000-11-30 | 2008-07-10 | Medarex, Inc., Milpitas | Transchromosomale transgen-nagetiere zur herstellung von humanen antikörpern |
| AU2002368077B2 (en) | 2001-07-12 | 2010-03-04 | Jefferson Foote | Super humanized antibodies |
| WO2003075855A2 (en) | 2002-03-08 | 2003-09-18 | Protein Design Labs, Inc. | Antibodies against cancer antigen tmeff2 and uses thereof |
| WO2006028936A2 (en) | 2004-09-02 | 2006-03-16 | Genentech, Inc. | Heteromultimeric molecules |
| KR101374454B1 (ko) | 2005-03-31 | 2014-03-17 | 추가이 세이야쿠 가부시키가이샤 | 회합제어에 의한 폴리펩티드 제조방법 |
| DE102005028778A1 (de) | 2005-06-22 | 2006-12-28 | SUNJÜT Deutschland GmbH | Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage |
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| WO2007147901A1 (en) | 2006-06-22 | 2007-12-27 | Novo Nordisk A/S | Production of bispecific antibodies |
| CN101952312A (zh) | 2007-07-31 | 2011-01-19 | 米迪缪尼有限公司 | 多特异性表位结合蛋白及其应用 |
| BRPI0818780A2 (pt) * | 2007-10-19 | 2015-04-22 | Genentech Inc | Anticorpo anti-tenb2 planejados por cisteína e conjugados de medicamento com anticorpos |
| US8748356B2 (en) | 2007-10-19 | 2014-06-10 | Janssen Biotech, Inc. | Methods for use in human-adapting monoclonal antibodies |
| AU2008343589A1 (en) | 2007-12-19 | 2009-07-09 | Centocor Ortho Biotech Inc. | Design and generation of human de novo pIX phage display libraries via fusion to pIX or pVII, vectors, antibodies and methods |
| US8227577B2 (en) | 2007-12-21 | 2012-07-24 | Hoffman-La Roche Inc. | Bivalent, bispecific antibodies |
| US9266967B2 (en) | 2007-12-21 | 2016-02-23 | Hoffmann-La Roche, Inc. | Bivalent, bispecific antibodies |
| US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
| US8242247B2 (en) | 2007-12-21 | 2012-08-14 | Hoffmann-La Roche Inc. | Bivalent, bispecific antibodies |
| JP2012505654A (ja) | 2008-10-14 | 2012-03-08 | ヤンセン バイオテツク,インコーポレーテツド | 抗体をヒト化及び親和性成熟する方法 |
| US9067986B2 (en) | 2009-04-27 | 2015-06-30 | Oncomed Pharmaceuticals, Inc. | Method for making heteromultimeric molecules |
| PT2560993T (pt) | 2010-04-20 | 2024-09-16 | Genmab As | Proteínas contendo anticorpo heterodimérico fc e métodos para a produção das mesmas |
| CN103429620B (zh) | 2010-11-05 | 2018-03-06 | 酵活有限公司 | 在Fc结构域中具有突变的稳定异源二聚的抗体设计 |
| US9574010B2 (en) | 2011-11-04 | 2017-02-21 | Zymeworks Inc. | Stable heterodimeric antibody design with mutations in the Fc domain |
| US20150030602A1 (en) | 2011-12-23 | 2015-01-29 | Phenoquest Ag | Antibodies for the treatment and diagnosis of affective and anxiety disorders |
| WO2014093908A2 (en) | 2012-12-14 | 2014-06-19 | Omt, Inc. | Polynucleotides encoding rodent antibodies with human idiotypes and animals comprising same |
| PT2970980T (pt) | 2013-03-15 | 2018-11-19 | Janssen Biotech Inc | Métodos de produção para controlor o teor de lisina c-terminal, galactose e ácido siálico em proteínas recombinantes |
| TWI680138B (zh) * | 2014-01-23 | 2019-12-21 | 美商再生元醫藥公司 | 抗pd-l1之人類抗體 |
| DK3189081T3 (da) | 2014-09-05 | 2020-05-04 | Janssen Pharmaceutica Nv | Cd123-bindende midler og anvendelser deraf |
| EP3778640A1 (en) * | 2015-05-01 | 2021-02-17 | Genentech, Inc. | Masked anti-cd3 antibodies and methods of use |
| EP3310811B1 (en) * | 2015-06-16 | 2021-06-16 | Genentech, Inc. | Anti-cd3 antibodies and methods of use |
| PT3370768T (pt) * | 2015-11-03 | 2022-04-21 | Janssen Biotech Inc | Anticorpos que se ligam especificamente ao pd-1 e seus usos |
| WO2019220368A1 (en) * | 2018-05-16 | 2019-11-21 | Janssen Biotech, Inc. | Bcma/cd3 and gprdc5d/cd3 bispecific antibodies for use in cancer therapy |
| BR112020023508A2 (pt) | 2018-05-24 | 2021-03-30 | Janssen Biotech, Inc. | Anticorpos anti-cd3 e usos dos mesmos |
-
2019
- 2019-05-21 EA EA202092849A patent/EA202092849A1/ru unknown
- 2019-05-21 EP EP19737217.0A patent/EP3802607A2/en active Pending
- 2019-05-21 CR CR20200564A patent/CR20200564A/es unknown
- 2019-05-21 JO JOP/2020/0295A patent/JOP20200295A1/ar unknown
- 2019-05-21 US US16/417,889 patent/US11866499B2/en active Active
- 2019-05-21 BR BR112020023416-8A patent/BR112020023416A2/pt unknown
- 2019-05-21 AU AU2019274652A patent/AU2019274652B2/en active Active
- 2019-05-21 KR KR1020207036922A patent/KR20210011999A/ko not_active Ceased
- 2019-05-21 CN CN201980034951.1A patent/CN112703203B/zh active Active
- 2019-05-21 WO PCT/IB2019/054184 patent/WO2019224713A2/en not_active Ceased
- 2019-05-21 CA CA3101304A patent/CA3101304A1/en active Pending
- 2019-05-21 MX MX2020012589A patent/MX2020012589A/es unknown
- 2019-05-21 PE PE2020001881A patent/PE20210634A1/es unknown
- 2019-05-21 MA MA052772A patent/MA52772A/fr unknown
- 2019-05-21 SG SG11202011268VA patent/SG11202011268VA/en unknown
- 2019-05-21 JP JP2020565399A patent/JP2021524255A/ja active Pending
- 2019-05-22 TW TW108117613A patent/TWI865451B/zh active
- 2019-05-24 AR ARP190101399A patent/AR115419A1/es not_active Application Discontinuation
- 2019-05-24 UY UY0001038243A patent/UY38243A/es unknown
-
2020
- 2020-11-13 PH PH12020551948A patent/PH12020551948A1/en unknown
- 2020-11-19 IL IL278862A patent/IL278862A/en unknown
- 2020-11-23 NI NI202000087A patent/NI202000087A/es unknown
- 2020-11-23 EC ECSENADI202075234A patent/ECSP20075234A/es unknown
- 2020-11-23 CL CL2020003032A patent/CL2020003032A1/es unknown
- 2020-11-23 CO CONC2020/0014515A patent/CO2020014515A2/es unknown
-
2024
- 2024-05-09 JP JP2024076617A patent/JP2024105476A/ja active Pending
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