UY38243A - Anticuerpos anti-tmeff2 monoespecíficos y multiespecíficos y sus usos - Google Patents

Anticuerpos anti-tmeff2 monoespecíficos y multiespecíficos y sus usos

Info

Publication number
UY38243A
UY38243A UY0001038243A UY38243A UY38243A UY 38243 A UY38243 A UY 38243A UY 0001038243 A UY0001038243 A UY 0001038243A UY 38243 A UY38243 A UY 38243A UY 38243 A UY38243 A UY 38243A
Authority
UY
Uruguay
Prior art keywords
monospecific
specific anti
tmeff2 antibodies
antibodies
tmeff2
Prior art date
Application number
UY0001038243A
Other languages
English (en)
Inventor
Sanjaya Singh
Philip Cooper
Robin Ernst
Rajkumar Ganesan
Colleen Kane
Michael Russell
Sathyadevi Venkataramani
Wu Sheng-Jiun
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of UY38243A publication Critical patent/UY38243A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Abstract

La descripción proporcionada en la presente descripción se refiere a anticuerpos anti-TMEFF2 monoespecíficos y multiespecíficos, y a métodos para producir y usar los anticuerpos descritos.
UY0001038243A 2018-05-24 2019-05-24 Anticuerpos anti-tmeff2 monoespecíficos y multiespecíficos y sus usos UY38243A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862675957P 2018-05-24 2018-05-24

Publications (1)

Publication Number Publication Date
UY38243A true UY38243A (es) 2019-11-29

Family

ID=67211771

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001038243A UY38243A (es) 2018-05-24 2019-05-24 Anticuerpos anti-tmeff2 monoespecíficos y multiespecíficos y sus usos

Country Status (25)

Country Link
US (1) US11866499B2 (es)
EP (1) EP3802607A2 (es)
JP (1) JP2021524255A (es)
KR (1) KR20210011999A (es)
CN (1) CN112703203A (es)
AR (1) AR115419A1 (es)
AU (1) AU2019274652A1 (es)
BR (1) BR112020023416A2 (es)
CA (1) CA3101304A1 (es)
CL (1) CL2020003032A1 (es)
CO (1) CO2020014515A2 (es)
CR (1) CR20200564A (es)
EA (1) EA202092849A1 (es)
EC (1) ECSP20075234A (es)
IL (1) IL278862A (es)
JO (1) JOP20200295A1 (es)
MA (1) MA52772A (es)
MX (1) MX2020012589A (es)
NI (1) NI202000087A (es)
PE (1) PE20210634A1 (es)
PH (1) PH12020551948A1 (es)
SG (1) SG11202011268VA (es)
TW (1) TW202003584A (es)
UY (1) UY38243A (es)
WO (1) WO2019224713A2 (es)

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JOP20200302A1 (ar) 2018-05-24 2020-11-23 Janssen Biotech Inc الأجسام المضادة لـ cd3 واستخداماتها
CN115175702A (zh) * 2019-12-18 2022-10-11 詹森生物科技公司 用于体内生物靶向的材料和方法
US20230374140A1 (en) * 2020-10-09 2023-11-23 Memorial Sloan Kettering Cancer Center Compositions targeting ndc80/mhc complexes and uses thereof
EP4228693A1 (en) 2020-10-13 2023-08-23 Janssen Biotech, Inc. Bioengineered t cell mediated immunity, materials and other methods for modulating cluster of differentiation iv &/or viii
WO2023164510A1 (en) 2022-02-23 2023-08-31 Xencor, Inc. Anti-cd28 x anti-psma antibodies
WO2024052831A1 (en) * 2022-09-09 2024-03-14 Janssen Biotech, Inc. Method of treating cancer with an anti tmeff2xcd3 bispecific antibody

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Also Published As

Publication number Publication date
CA3101304A1 (en) 2019-11-28
SG11202011268VA (en) 2020-12-30
AU2019274652A1 (en) 2020-11-26
MA52772A (fr) 2021-04-14
US11866499B2 (en) 2024-01-09
AR115419A1 (es) 2021-01-13
CN112703203A (zh) 2021-04-23
WO2019224713A2 (en) 2019-11-28
EP3802607A2 (en) 2021-04-14
EA202092849A1 (ru) 2021-03-16
MX2020012589A (es) 2021-01-29
ECSP20075234A (es) 2020-12-31
PH12020551948A1 (en) 2021-08-16
KR20210011999A (ko) 2021-02-02
JOP20200295A1 (ar) 2020-11-22
TW202003584A (zh) 2020-01-16
PE20210634A1 (es) 2021-03-23
CR20200564A (es) 2021-06-21
JP2021524255A (ja) 2021-09-13
NI202000087A (es) 2021-03-23
IL278862A (en) 2021-01-31
BR112020023416A2 (pt) 2021-02-17
US20190359711A1 (en) 2019-11-28
CL2020003032A1 (es) 2021-04-16
WO2019224713A3 (en) 2020-01-02
CO2020014515A2 (es) 2020-12-10

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