JP2023543152A5 - - Google Patents
Info
- Publication number
- JP2023543152A5 JP2023543152A5 JP2023516061A JP2023516061A JP2023543152A5 JP 2023543152 A5 JP2023543152 A5 JP 2023543152A5 JP 2023516061 A JP2023516061 A JP 2023516061A JP 2023516061 A JP2023516061 A JP 2023516061A JP 2023543152 A5 JP2023543152 A5 JP 2023543152A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- antigen
- binding molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063080172P | 2020-09-18 | 2020-09-18 | |
| US63/080,172 | 2020-09-18 | ||
| PCT/US2021/050850 WO2022061098A1 (en) | 2020-09-18 | 2021-09-17 | Antigen-binding molecules that bind cd38 and/or cd28, and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023543152A JP2023543152A (ja) | 2023-10-13 |
| JP2023543152A5 true JP2023543152A5 (enExample) | 2025-09-30 |
| JP7905328B2 JP7905328B2 (ja) | 2026-08-14 |
Family
ID=78135158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023516061A Active JP7905328B2 (ja) | 2020-09-18 | 2021-09-17 | Ｃｄ３８及び／又はｃｄ２８を結合する抗原結合分子及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11905332B2 (enExample) |
| EP (1) | EP4214234A1 (enExample) |
| JP (1) | JP7905328B2 (enExample) |
| KR (1) | KR20230070259A (enExample) |
| CN (1) | CN116348495A (enExample) |
| AU (1) | AU2021345262A1 (enExample) |
| CA (1) | CA3191839A1 (enExample) |
| CL (3) | CL2023000761A1 (enExample) |
| CO (1) | CO2023004448A2 (enExample) |
| IL (1) | IL301037A (enExample) |
| MX (1) | MX2023003214A (enExample) |
| WO (1) | WO2022061098A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119143875A (zh) | 2018-06-21 | 2024-12-17 | 瑞泽恩制药公司 | 双特异性抗psma x抗cd28抗体及其用途 |
| US11919958B2 (en) | 2020-08-19 | 2024-03-05 | Xencor, Inc. | Anti-CD28 compositions |
| JP7905328B2 (ja) | 2020-09-18 | 2026-08-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Ｃｄ３８及び／又はｃｄ２８を結合する抗原結合分子及びその使用 |
| EP4320156A1 (en) | 2021-04-09 | 2024-02-14 | Ose Immunotherapeutics | Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains |
| IL314993A (en) | 2022-02-23 | 2024-10-01 | Xencor Inc | Anti-cd28 x anti-psma antibodies |
| CA3252182A1 (en) * | 2022-05-18 | 2023-11-23 | Regeneron Pharmaceuticals, Inc. | MULTISPECIFIC ANTIGEN-BINDING MOLECULES THAT BIND TO CD38 AND 4-1BB AND ASSOCIATED USES |
| AU2023356326A1 (en) | 2022-10-06 | 2025-03-27 | Bicara Therapeutics Inc. | Multispecific proteins and related methods |
| CN121586731A (zh) * | 2023-07-31 | 2026-02-27 | 赛诺菲 | 抗cd38 t细胞接合器在治疗外周t细胞淋巴瘤中的方法和用途 |
| WO2025026356A1 (zh) * | 2023-07-31 | 2025-02-06 | 百奥泰生物制药股份有限公司 | 靶向肿瘤相关抗原与cd28的双特异性抗体及其应用 |
| CN117054649A (zh) * | 2023-08-04 | 2023-11-14 | 广州中医药大学第一附属医院 | 一种慢性萎缩性胃炎向胃癌转化标志物及其应用 |
| CN119101160B (zh) * | 2024-10-25 | 2025-02-11 | 江苏百英生物科技有限公司 | 一种抗cd28纳米抗体、基于天然库筛选cd28纳米抗体的方法及其应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| EP0590058B1 (en) | 1991-06-14 | 2003-11-26 | Genentech, Inc. | HUMANIZED Heregulin ANTIBODy |
| ATE537190T1 (de) | 2006-06-02 | 2011-12-15 | Regeneron Pharma | Hochaffine antikörper gegen den humanen il-6- rezeptor |
| GB0624500D0 (en) * | 2006-12-07 | 2007-01-17 | Istituto Superiore Di Sanito | A novel passive vaccine for candida infections |
| TWI507525B (zh) | 2009-06-26 | 2015-11-11 | Regeneron Pharma | 具天然免疫球蛋白形式之易分離的雙專一性抗體 |
| SG183149A1 (en) | 2010-02-08 | 2012-09-27 | Regeneron Pharma | Common light chain mouse |
| JOP20200236A1 (ar) | 2012-09-21 | 2017-06-16 | Regeneron Pharma | الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها |
| TWI682941B (zh) | 2013-02-01 | 2020-01-21 | 美商再生元醫藥公司 | 含嵌合恆定區之抗體 |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| CA2874083C (en) * | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
| EP3443006B1 (en) * | 2016-04-13 | 2023-08-02 | Sanofi | Trispecific and/or trivalent binding proteins |
| US11124577B2 (en) | 2016-11-02 | 2021-09-21 | Engmab Sàrl | Bispecific antibody against BCMA and CD3 and an immunological drug for combined use in treating multiple myeloma |
| EP3615068A1 (en) * | 2017-04-28 | 2020-03-04 | Novartis AG | Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor |
| CN111788225B (zh) * | 2017-10-10 | 2025-02-18 | 赛诺菲 | 抗cd38抗体及与抗cd3和抗cd28抗体的组合 |
| CN119143875A (zh) * | 2018-06-21 | 2024-12-17 | 瑞泽恩制药公司 | 双特异性抗psma x抗cd28抗体及其用途 |
| TWI838389B (zh) | 2018-07-19 | 2024-04-11 | 美商再生元醫藥公司 | 雙特異性抗-BCMAｘ抗-CD3抗體及其用途 |
| WO2020132024A1 (en) | 2018-12-19 | 2020-06-25 | Regeneron Pharmaceuticals, Inc. | Bispecific anti-muc16 x anti-cd28 antibodies and uses thereof |
| KR20210104836A (ko) | 2018-12-19 | 2021-08-25 | 리제너론 파아마슈티컬스, 인크. | 이중 특이적 항-cd28 x 항-cd22 항체 및 그의 용도 |
| CR20210326A (es) * | 2018-12-21 | 2021-09-10 | Hoffmann La Roche | Moléculas agonistas de unión al antígeno cd28 que actúan sobre el tumor |
| JP7905328B2 (ja) | 2020-09-18 | 2026-08-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Ｃｄ３８及び／又はｃｄ２８を結合する抗原結合分子及びその使用 |
-
2021
- 2021-09-17 JP JP2023516061A patent/JP7905328B2/ja active Active
- 2021-09-17 CN CN202180068348.2A patent/CN116348495A/zh active Pending
- 2021-09-17 IL IL301037A patent/IL301037A/en unknown
- 2021-09-17 EP EP21791138.7A patent/EP4214234A1/en active Pending
- 2021-09-17 MX MX2023003214A patent/MX2023003214A/es unknown
- 2021-09-17 WO PCT/US2021/050850 patent/WO2022061098A1/en not_active Ceased
- 2021-09-17 CA CA3191839A patent/CA3191839A1/en active Pending
- 2021-09-17 AU AU2021345262A patent/AU2021345262A1/en active Pending
- 2021-09-17 US US17/477,870 patent/US11905332B2/en active Active
- 2021-09-17 KR KR1020237012986A patent/KR20230070259A/ko active Pending
-
2023
- 2023-03-16 CL CL2023000761A patent/CL2023000761A1/es unknown
- 2023-04-11 CO CONC2023/0004448A patent/CO2023004448A2/es unknown
-
2024
- 2024-01-23 US US18/420,588 patent/US12590168B2/en active Active
-
2025
- 2025-01-16 CL CL2025000134A patent/CL2025000134A1/es unknown
- 2025-10-07 CL CL2025003055A patent/CL2025003055A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11692035B2 (en) | Therapeutic CD47 antibodies | |
| JP2021531005A5 (enExample) | ||
| US11202828B2 (en) | Therapeutic SIRP-α antibodies | |
| FI3823664T3 (fi) | Bispesifisiä anti-BCMA- x anti-CD3-vasta-aineita ja niiden käyttöjä | |
| JP2021518103A5 (enExample) | ||
| JP2021527431A5 (enExample) | ||
| CN110536903A (zh) | 抗ox40抗体及其用途 | |
| JP2021524249A5 (enExample) | ||
| JP2022526764A5 (enExample) | ||
| JP2022510964A5 (enExample) | ||
| JP7170331B2 (ja) | 固形及び血液癌の治療のための併用療法 | |
| US20170015758A1 (en) | Compositions And Methods For Modulating And Redirecting Immune Responses | |
| JP2021506244A5 (enExample) | ||
| AU2018348429A1 (en) | Multispecific antibody | |
| WO2009114335A2 (en) | Pd-1 binding proteins | |
| WO2019072870A1 (en) | ANTIBODIES TARGETING CD137 AND METHODS OF USE | |
| US20190309066A1 (en) | Combination therapy for the treatment of solid and hematological cancers | |
| US20220313819A1 (en) | Combination therapy for the treatment of solid and hematological cancers | |
| CN112292399A (zh) | 抗cd27抗体及其用途 | |
| JP2021520201A5 (enExample) | ||
| WO2020198370A2 (en) | Therapeutic cd47 antibodies | |
| CN115210261A (zh) | 抗半乳糖凝集素-9抗体及其用途 | |
| WO2021263085A2 (en) | Combination therapy for the treatment of solid and hematological cancers | |
| RU2025113775A (ru) | Биспецифические антитела против cd3 и cd20 собаки | |
| CN121620534A (zh) | 抗tigit抗体及其用途 |