|
NZ250844A
(en)
|
1993-04-07 |
1996-03-26 |
Pfizer |
Treatment of non-insulin dependant diabetes with peptides; composition
|
|
US6284727B1
(en)
|
1993-04-07 |
2001-09-04 |
Scios, Inc. |
Prolonged delivery of peptides
|
|
US5424286A
(en)
|
1993-05-24 |
1995-06-13 |
Eng; John |
Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same
|
|
US5641757A
(en)
|
1994-12-21 |
1997-06-24 |
Ortho Pharmaceutical Corporation |
Stable 2-chloro-2'-deoxyadenosine formulations
|
|
WO1998005351A1
(en)
|
1996-08-08 |
1998-02-12 |
Amylin Pharmaceuticals, Inc. |
Methods for regulating gastrointestinal motility
|
|
ES2283025T3
(es)
|
1996-08-30 |
2007-10-16 |
Novo Nordisk A/S |
Derivados de glp-1.1.
|
|
US6458924B2
(en)
|
1996-08-30 |
2002-10-01 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
DE69831673C5
(de)
|
1997-01-07 |
2015-01-22 |
Amylin Pharmaceuticals, Llc |
Verwendung von exedinen und deren antagonisten zur verminderung der lebensmittelaufnahme
|
|
US7312196B2
(en)
|
1997-01-08 |
2007-12-25 |
Amylin Pharmaceuticals, Inc. |
Formulations for amylin agonist peptides
|
|
US6410511B2
(en)
|
1997-01-08 |
2002-06-25 |
Amylin Pharmaceuticals, Inc. |
Formulations for amylin agonist peptides
|
|
US6723530B1
(en)
|
1997-02-05 |
2004-04-20 |
Amylin Pharmaceuticals, Inc. |
Polynucleotides encoding proexendin, and methods and uses thereof
|
|
CA2299425A1
(en)
|
1997-08-08 |
1999-02-18 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
US7157555B1
(en)
|
1997-08-08 |
2007-01-02 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
US7223725B1
(en)
|
1997-11-14 |
2007-05-29 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
US7220721B1
(en)
|
1997-11-14 |
2007-05-22 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist peptides
|
|
CA2309356C
(en)
|
1997-11-14 |
2010-09-21 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
EP1066314B1
(en)
|
1997-11-14 |
2007-12-26 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
DK1044015T3
(da)
|
1998-01-09 |
2008-12-08 |
Amylin Pharmaceuticals Inc |
Formuleringer med amylinagonistpeptider og insulin
|
|
US6703359B1
(en)
|
1998-02-13 |
2004-03-09 |
Amylin Pharmaceuticals, Inc. |
Inotropic and diuretic effects of exendin and GLP-1
|
|
WO1999043708A1
(en)
|
1998-02-27 |
1999-09-02 |
Novo Nordisk A/S |
Glp-1 derivatives of glp-1 and exendin with protracted profile of action
|
|
CA2321026A1
(en)
|
1998-03-09 |
1999-09-16 |
Zealand Pharmaceuticals A/S |
Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
|
|
AU2612599A
(en)
|
1998-03-13 |
1999-10-11 |
Novo Nordisk A/S |
Stabilized aqueous peptide solutions
|
|
US6998387B1
(en)
|
1998-03-19 |
2006-02-14 |
Amylin Pharmaceuticals, Inc. |
Human appetite control by glucagon-like peptide receptor binding compounds
|
|
EP1419783A3
(en)
|
1998-06-12 |
2005-01-12 |
Amylin Pharmaceuticals, Inc. |
Use of a composition comprising an exendin or a compound derived therefrom and a pharmaceutical carrier
|
|
EP2028269B1
(en)
|
1998-08-10 |
2015-10-21 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Differentiation of non-insulin producing cells into insulin producing cells by GLP-1 or Exendin-4 and uses thereof
|
|
EP1113799A4
(en)
|
1998-09-17 |
2004-06-09 |
Lilly Co Eli |
PROTEIN-BASED PREPARATION
|
|
US6284725B1
(en)
|
1998-10-08 |
2001-09-04 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue
|
|
US7259136B2
(en)
|
1999-04-30 |
2007-08-21 |
Amylin Pharmaceuticals, Inc. |
Compositions and methods for treating peripheral vascular disease
|
|
US6429197B1
(en)
|
1998-10-08 |
2002-08-06 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 or its biologically active analogues to improve the function of the ischemic and reperfused brain
|
|
AU2373400A
(en)
|
1998-12-22 |
2000-07-12 |
Eli Lilly And Company |
Shelf-stable formulation of glucagon-like peptide-1
|
|
US20030087820A1
(en)
|
1999-01-14 |
2003-05-08 |
Young Andrew A. |
Novel exendin agonist formulations and methods of administration thereof
|
|
BRPI0007820B8
(pt)
|
1999-01-14 |
2021-05-25 |
Amylin Pharmaceuticals Llc |
formulações farmacêuticas agonistas de exendina e seus usos
|
|
BRPI0007823A8
(pt)
|
1999-01-14 |
2017-03-21 |
Amylin Pharmaceuticals Inc |
Métodos de supressão do glucagon
|
|
US7399489B2
(en)
|
1999-01-14 |
2008-07-15 |
Amylin Pharmaceuticals, Inc. |
Exendin analog formulations
|
|
CN1344248A
(zh)
|
1999-03-17 |
2002-04-10 |
诺沃挪第克公司 |
肽的酰化方法和新酰化剂
|
|
US6451974B1
(en)
|
1999-03-17 |
2002-09-17 |
Novo Nordisk A/S |
Method of acylating peptides and novel acylating agents
|
|
US6924264B1
(en)
|
1999-04-30 |
2005-08-02 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
CN1372570A
(zh)
|
1999-04-30 |
2002-10-02 |
安米林药品公司 |
修饰的exendin和exendin激动剂
|
|
US6849714B1
(en)
|
1999-05-17 |
2005-02-01 |
Conjuchem, Inc. |
Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
|
|
US6514500B1
(en)
|
1999-10-15 |
2003-02-04 |
Conjuchem, Inc. |
Long lasting synthetic glucagon like peptide {GLP-!}
|
|
US6887470B1
(en)
|
1999-09-10 |
2005-05-03 |
Conjuchem, Inc. |
Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
|
|
CN1191273C
(zh)
|
1999-05-17 |
2005-03-02 |
康久化学公司 |
长效促胰岛肽
|
|
US6482799B1
(en)
|
1999-05-25 |
2002-11-19 |
The Regents Of The University Of California |
Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial
|
|
US6506724B1
(en)
|
1999-06-01 |
2003-01-14 |
Amylin Pharmaceuticals, Inc. |
Use of exendins and agonists thereof for the treatment of gestational diabetes mellitus
|
|
US6344180B1
(en)
|
1999-06-15 |
2002-02-05 |
Bionebraska, Inc. |
GLP-1 as a diagnostic test to determine β-cell function and the presence of the condition of IGT and type II diabetes
|
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
|
US6972319B1
(en)
|
1999-09-28 |
2005-12-06 |
Bayer Pharmaceuticals Corporation |
Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
|
|
GB9930882D0
(en)
|
1999-12-30 |
2000-02-23 |
Nps Allelix Corp |
GLP-2 formulations
|
|
ATE275967T1
(de)
|
2000-01-10 |
2004-10-15 |
Amylin Pharmaceuticals Inc |
Verwendung von exendinen und deren agonisten zur behandlung von hypertriglyceridämie
|
|
MXPA02009031A
(es)
|
2000-03-14 |
2004-08-19 |
Amylin Pharmaceuticals Inc |
Efectos del peptido-1(7-36) tipo glucagon en la motilidad antro-piloro.duodenal.
|
|
CA2380423A1
(en)
|
2000-05-17 |
2001-11-22 |
Bionebraska, Inc. |
Peptide pharmaceutical formulations
|
|
CN1462191B
(zh)
|
2000-05-19 |
2013-07-24 |
埃米林药品公司 |
Glp-1用于制备治疗急性冠脉综合征的药物的用途
|
|
AU2001284985A1
(en)
|
2000-08-18 |
2002-03-04 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
|
US7507714B2
(en)
|
2000-09-27 |
2009-03-24 |
Bayer Corporation |
Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
|
|
AU775663B2
(en)
|
2000-10-20 |
2004-08-12 |
Amylin Pharmaceuticals, Inc. |
Treatment of hibernating myocardium and diabetic cardiomyopathy with a GLP-1 peptide
|
|
EP1355942B1
(en)
|
2000-12-07 |
2008-08-27 |
Eli Lilly And Company |
Glp-1 fusion proteins
|
|
US7259233B2
(en)
|
2000-12-13 |
2007-08-21 |
Eli Lilly And Company |
Chronic treatment regimen using glucagon-like insulinotropic peptides
|
|
GB2371227A
(en)
|
2001-01-10 |
2002-07-24 |
Grandis Biotech Gmbh |
Crystallisation - resistant aqueous growth hormone formulations
|
|
US6573237B2
(en)
|
2001-03-16 |
2003-06-03 |
Eli Lilly And Company |
Protein formulations
|
|
CN1162446C
(zh)
|
2001-05-10 |
2004-08-18 |
上海华谊生物技术有限公司 |
促胰岛素分泌肽衍生物
|
|
JP2005506956A
(ja)
|
2001-06-01 |
2005-03-10 |
イーライ・リリー・アンド・カンパニー |
長時間作用性ｇｌｐ−１製剤
|
|
JP5562510B2
(ja)
|
2001-06-28 |
2014-07-30 |
ノヴォ ノルディスク アー／エス |
修飾ｇｌｐ−１の安定な処方剤
|
|
CA2652991A1
(en)
|
2001-07-16 |
2003-11-13 |
Caprotec Bioanalytics Gmbh |
Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
|
|
JP2005501058A
(ja)
|
2001-07-31 |
2005-01-13 |
ザ ガバメント オブ ザ ユナイテッドステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ ザ ナショナル インステ |
Ｇｌｐ−１、ｅｘｅｎｄｉｎ−４、そのペプチド・アナログ及びその使用
|
|
EP1432430A4
(en)
|
2001-08-28 |
2006-05-10 |
Lilly Co Eli |
PREMIXTURES OF GLP-1 AND BASALINSULIN
|
|
JP2005508360A
(ja)
|
2001-10-19 |
2005-03-31 |
イーライ・リリー・アンド・カンパニー |
Ｇｌｐ−１およびインスリンの二相混合物
|
|
EP2990417A1
(en)
|
2001-12-21 |
2016-03-02 |
Human Genome Sciences, Inc. |
Albumin insulin fusion protein
|
|
CA2484556A1
(en)
|
2001-12-21 |
2003-07-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
US7105489B2
(en)
|
2002-01-22 |
2006-09-12 |
Amylin Pharmaceuticals, Inc. |
Methods and compositions for treating polycystic ovary syndrome
|
|
JP4417113B2
(ja)
|
2002-02-20 |
2010-02-17 |
エミスフェアー・テクノロジーズ・インク |
Ｇｌｐ−１分子の投与方法
|
|
DK1478394T3
(da)
|
2002-02-27 |
2008-10-13 |
Immunex Corp |
Stabiliseret TNFR-Fc formulation med arginin
|
|
DE60325847D1
(de)
|
2002-03-11 |
2009-03-05 |
Caprotec Bioanalytics Gmbh |
Verbindungen und verfahren für die analyse des proteoms
|
|
US7141240B2
(en)
|
2002-03-12 |
2006-11-28 |
Cedars-Sinai Medical Center |
Glucose-dependent insulin-secreting cells transfected with a nucleotide sequence encoding GLP-1
|
|
AU2003226913A1
(en)
|
2002-04-04 |
2003-10-20 |
Novo Nordisk A/S |
Glp-1 agonist and cardiovascular complications
|
|
NZ535684A
(en)
|
2002-04-10 |
2006-03-31 |
Lilly Co Eli |
Use of a GLP-1 (glucagon like peptide-1) compound to treat gastroparesis by increasing gastric emptying
|
|
US6861236B2
(en)
|
2002-05-24 |
2005-03-01 |
Applied Nanosystems B.V. |
Export and modification of (poly)peptides in the lantibiotic way
|
|
AU2003232172A1
(en)
|
2002-06-14 |
2003-12-31 |
Novo Nordisk A/S |
Combined use of a modulator of cd3 and a glp-1 compound
|
|
US20040037826A1
(en)
|
2002-06-14 |
2004-02-26 |
Michelsen Birgitte Koch |
Combined use of a modulator of CD3 and a GLP-1 compound
|
|
DE10227232A1
(de)
|
2002-06-18 |
2004-01-15 |
Aventis Pharma Deutschland Gmbh |
Saure Insulinzubereitungen mit verbesserter Stabilität
|
|
MXPA04012497A
(es)
|
2002-07-04 |
2005-07-14 |
Zealand Pharma As |
Glp-1 y metodos para tratar la diabetes.
|
|
US20070065469A1
(en)
|
2002-07-09 |
2007-03-22 |
Michael Betz |
Liquid formulations with high concentration of human growth hormone (high) comprising glycine
|
|
CA2491685A1
(en)
|
2002-07-09 |
2004-01-15 |
Sandoz Ag |
Liquid formulations with high concentration of human growth hormone (hgh) comprising 1,2-prolpylene glycol
|
|
US20040038865A1
(en)
|
2002-08-01 |
2004-02-26 |
Mannkind Corporation |
Cell transport compositions and uses thereof
|
|
US20080260838A1
(en)
|
2003-08-01 |
2008-10-23 |
Mannkind Corporation |
Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
|
|
JP4828940B2
(ja)
|
2002-08-01 |
2011-11-30 |
マンカインド コーポレイション |
細胞輸送組成物およびこれらの使用
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
DK1532149T3
(da)
|
2002-08-21 |
2010-05-10 |
Boehringer Ingelheim Pharma |
8-[3-amino-piperiden-1-yl]-xanthiner, fremstilling deraf og anvendelse deraf som lægemiddel
|
|
WO2004035623A2
(en)
|
2002-10-02 |
2004-04-29 |
Zealand Pharma A/S |
Stabilized exendin-4 compounds
|
|
US6969702B2
(en)
|
2002-11-20 |
2005-11-29 |
Neuronova Ab |
Compounds and methods for increasing neurogenesis
|
|
US20050209142A1
(en)
|
2002-11-20 |
2005-09-22 |
Goran Bertilsson |
Compounds and methods for increasing neurogenesis
|
|
DK1583541T3
(da)
|
2002-11-20 |
2011-04-11 |
Neuronova Ab |
Forbindelser og fremgangsmåder til at øge neurogenese
|
|
WO2004056313A2
(en)
|
2002-12-17 |
2004-07-08 |
Amylin Pharmaceuticals, Inc. |
Prevention and treatment of cardiac arrhythmias
|
|
US20040209803A1
(en)
|
2002-12-19 |
2004-10-21 |
Alain Baron |
Compositions for the treatment and prevention of nephropathy
|
|
US7790681B2
(en)
|
2002-12-17 |
2010-09-07 |
Amylin Pharmaceuticals, Inc. |
Treatment of cardiac arrhythmias with GLP-1 receptor ligands
|
|
GB0300571D0
(en)
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
PL1620118T3
(pl)
|
2003-04-08 |
2014-11-28 |
Yeda Res & Dev |
Leki odwracalnie pegylowane
|
|
WO2004089985A1
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
Stable pharmaceutical compositions
|
|
CA2525574C
(en)
|
2003-05-15 |
2015-06-30 |
Trustees Of Tufts College |
Stable analogs of peptide and polypeptide therapeutics
|
|
US7947261B2
(en)
|
2003-05-23 |
2011-05-24 |
Nektar Therapeutics |
Conjugates formed from polymer derivatives having particular atom arrangements
|
|
NZ541374A
(en)
|
2003-05-23 |
2008-09-26 |
Nektar Therapeutics Al Corp |
PEG derivatives having an amidocarbonate linkage
|
|
WO2005000222A2
(en)
|
2003-05-30 |
2005-01-06 |
Amylin Pharmaceuticals, Inc. |
Novel methods and compositions for enhanced transmucosal delivery of peptides and proteins
|
|
EP1633391B1
(en)
|
2003-06-03 |
2011-10-19 |
Novo Nordisk A/S |
Stabilized pharmaceutical peptide compositions
|
|
KR101293507B1
(ko)
|
2003-06-03 |
2013-08-06 |
노보 노르디스크 에이/에스 |
안정화된 약학적 펩티드 조성물
|
|
CN102940879B
(zh)
|
2003-06-03 |
2017-06-06 |
诺沃挪第克公司 |
稳定化的药物肽组合物
|
|
EP2292253A3
(en)
|
2003-06-03 |
2011-12-14 |
Novo Nordisk A/S |
Stabilized pharmaceutical peptide compositions
|
|
US8921311B2
(en)
|
2003-08-01 |
2014-12-30 |
Mannkind Corporation |
Method for treating hyperglycemia
|
|
WO2005012347A2
(en)
|
2003-08-05 |
2005-02-10 |
Novo Nordisk A/S |
Novel insulin derivatives
|
|
RU2006103860A
(ru)
|
2003-08-21 |
2006-07-27 |
Ново Нордиск А/С (DK) |
Способ разделения полипептидов, содержащих рацемическую аминокислоту
|
|
JP5518282B2
(ja)
|
2003-09-01 |
2014-06-11 |
ノヴォ ノルディスク アー／エス |
安定なペプチドの製剤
|
|
US20060247167A1
(en)
|
2003-09-01 |
2006-11-02 |
Novo Nordisk A/S |
Stable formulations of peptides
|
|
WO2005028516A2
(en)
|
2003-09-19 |
2005-03-31 |
Novo Nordisk A/S |
Albumin-binding derivatives of therapeutic peptides
|
|
US20060287221A1
(en)
|
2003-11-13 |
2006-12-21 |
Novo Nordisk A/S |
Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
|
|
WO2005046716A1
(en)
|
2003-11-13 |
2005-05-26 |
Novo Nordisk A/S |
Soluble pharmaceutical compositions for parenteral administration comprising a glp-1 peptide and a insulin peptide of short time action for treatment of diabetes and bulimia
|
|
US20050106214A1
(en)
|
2003-11-14 |
2005-05-19 |
Guohua Chen |
Excipients in drug delivery vehicles
|
|
US20050281879A1
(en)
|
2003-11-14 |
2005-12-22 |
Guohua Chen |
Excipients in drug delivery vehicles
|
|
PL3300721T5
(pl)
|
2003-11-20 |
2025-11-17 |
Novo Nordisk A/S |
Preparaty peptydowe zawierające glikol propylenowy, które są optymalne do produkcji i do zastosowania w urządzeniu do wstrzykiwania
|
|
EP1750752A2
(en)
|
2003-11-20 |
2007-02-14 |
Neuronova AB |
Compounds and methods for increasing neurogenesis
|
|
AU2004295023A1
(en)
|
2003-12-03 |
2005-06-16 |
Novo Nordisk A/S |
Single-chain insulin
|
|
CN1913925A
(zh)
|
2003-12-10 |
2007-02-14 |
尼克塔治疗亚拉巴马公司 |
含有两组不同聚合物－活性剂缀合物的组合物
|
|
US20050143303A1
(en)
|
2003-12-26 |
2005-06-30 |
Nastech Pharmaceutical Company Inc. |
Intranasal administration of glucose-regulating peptides
|
|
US20060210614A1
(en)
|
2003-12-26 |
2006-09-21 |
Nastech Pharmaceutical Company Inc. |
Method of treatment of a metabolic disease using intranasal administration of exendin peptide
|
|
CN1938334A
(zh)
*
|
2004-01-30 |
2007-03-28 |
瓦拉塔药品公司 |
Glp－1激动剂和胃泌素化合物的联合使用
|
|
JP5638177B2
(ja)
|
2004-02-11 |
2014-12-10 |
アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc |
膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド
|
|
EP1718665B1
(en)
|
2004-02-11 |
2013-04-10 |
Amylin Pharmaceuticals, LLC |
Hybrid polypeptides with selectable properties
|
|
ES2345113T3
(es)
|
2004-02-11 |
2010-09-15 |
Amylin Pharmaceuticals, Inc. |
Peptidos de la familia amilina y metodos para su obtencion y utilizacion.
|
|
US8076288B2
(en)
|
2004-02-11 |
2011-12-13 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides having glucose lowering activity
|
|
US7399744B2
(en)
|
2004-03-04 |
2008-07-15 |
Amylin Pharmaceuticals, Inc. |
Methods for affecting body composition
|
|
EA200601904A1
(ru)
|
2004-04-15 |
2007-02-27 |
Алкермес, Инк. |
Система отсроченного высвобождения лекарственного средства на основе полимеров
|
|
US20060110423A1
(en)
|
2004-04-15 |
2006-05-25 |
Wright Steven G |
Polymer-based sustained release device
|
|
US7456254B2
(en)
|
2004-04-15 |
2008-11-25 |
Alkermes, Inc. |
Polymer-based sustained release device
|
|
US20090069226A1
(en)
|
2004-05-28 |
2009-03-12 |
Amylin Pharmaceuticals, Inc. |
Transmucosal delivery of peptides and proteins
|
|
WO2005117584A2
(en)
|
2004-05-28 |
2005-12-15 |
Amylin Pharmaceuticals, Inc |
Improved transmucosal delivery of peptides and proteins
|
|
EP2316446A1
(en)
|
2004-06-11 |
2011-05-04 |
Novo Nordisk A/S |
Counteracting drug-induced obesity using GLP-1 agonists
|
|
PT1773878E
(pt)
|
2004-07-19 |
2015-06-05 |
Biocon Ltd |
Conjugados de insulina-oligómero, formulaçôes e usos dos mesmos
|
|
WO2006091231A2
(en)
|
2004-07-21 |
2006-08-31 |
Ambrx, Inc. |
Biosynthetic polypeptides utilizing non-naturally encoded amino acids
|
|
AU2005271403A1
(en)
|
2004-08-03 |
2006-02-16 |
Biorexis Pharmaceutical Corporation |
Combination therapy using transferrin fusion proteins comprising GLP-1
|
|
EP1794512A1
(en)
|
2004-08-16 |
2007-06-13 |
Water Un Limited |
Apparatus and method for cooling of air
|
|
EP1789434B1
(en)
|
2004-08-31 |
2013-11-20 |
Novo Nordisk A/S |
Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins
|
|
DE102004043153B4
(de)
|
2004-09-03 |
2013-11-21 |
Philipps-Universität Marburg |
Erfindung betreffend GLP-1 und Exendin
|
|
TW200612991A
(en)
|
2004-09-07 |
2006-05-01 |
Chugai Pharmaceutical Co Ltd |
Process for producing water-soluble hyaluronic acid modification
|
|
EP1791554A2
(en)
|
2004-09-17 |
2007-06-06 |
Novo Nordisk A/S |
Pharmaceutical compositions containing insulin and insulinotropic peptide
|
|
CN101060831B
(zh)
|
2004-10-01 |
2010-06-23 |
拉姆斯科股份有限公司 |
可方便植入的缓释药物组合物
|
|
JP5107713B2
(ja)
|
2004-10-07 |
2012-12-26 |
ノヴォ ノルディスク アー／エス |
遅延性のエキセンディン−４化合物
|
|
US7595294B2
(en)
|
2004-10-08 |
2009-09-29 |
Transition Therapeutics, Inc. |
Vasoactive intestinal polypeptide pharmaceuticals
|
|
AU2005295756B2
(en)
|
2004-10-13 |
2012-02-02 |
Isis Parmaceuticals, Inc. |
Antisense modulation of PTP1B expression
|
|
US7442682B2
(en)
|
2004-10-19 |
2008-10-28 |
Nitto Denko Corporation |
Transepithelial delivery of peptides with incretin hormone activities
|
|
ES2735533T3
(es)
|
2004-11-12 |
2019-12-19 |
Novo Nordisk As |
Formulaciones estables de GLP-1
|
|
EP1814581B1
(en)
|
2004-11-12 |
2016-03-16 |
Novo Nordisk A/S |
Stable formulations of peptides comprising an acylated glp-1 analogue and a basal insuline
|
|
US20080125361A1
(en)
|
2004-11-12 |
2008-05-29 |
Novo Nordisk A/S |
Stable Formulations Of Peptides
|
|
EP1841796A2
(en)
|
2004-12-02 |
2007-10-10 |
Domantis Limited |
Bispecific domain antibodies targeting serum albumin and glp-1 or pyy
|
|
CA2588594C
(en)
|
2004-12-13 |
2014-02-18 |
Amylin Pharmaceuticals, Inc. |
Pancreatic polypeptide family motifs, polypeptides and methods comprising the same
|
|
US7851565B2
(en)
|
2004-12-21 |
2010-12-14 |
Nektar Therapeutics |
Stabilized polymeric thiol reagents
|
|
CN101044162B
(zh)
|
2004-12-22 |
2010-10-27 |
伊莱利利公司 |
Glp-1类似物融合蛋白质制剂
|
|
WO2006073890A2
(en)
|
2004-12-24 |
2006-07-13 |
Amylin Pharmaceuticals, Inc. |
Use of glp-1 and agonists thereof to prevent cardiac myocyte apoptosis
|
|
EP1845105A4
(en)
|
2005-01-14 |
2009-02-18 |
Wuxi Grandchamp Pharmaceutical |
MODIFIED EXENDINES AND CORRESPONDING USES
|
|
US8716221B2
(en)
|
2005-01-14 |
2014-05-06 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Modified exendins and uses thereof
|
|
WO2006082588A2
(en)
|
2005-02-07 |
2006-08-10 |
Pharmalight Inc. |
Method and device for ophthalmic administration of active pharmaceutical ingredients
|
|
AU2006213607A1
(en)
|
2005-02-11 |
2006-08-17 |
Amylin Pharmaceuticals, Llc |
GIP analog and hybrid polypeptides with selectable properties
|
|
US8263545B2
(en)
|
2005-02-11 |
2012-09-11 |
Amylin Pharmaceuticals, Inc. |
GIP analog and hybrid polypeptides with selectable properties
|
|
WO2006097535A2
(en)
|
2005-03-18 |
2006-09-21 |
Novo Nordisk A/S |
Peptide agonists of the glucagon family with secretin like activity
|
|
US8946149B2
(en)
|
2005-04-11 |
2015-02-03 |
Amylin Pharmaceuticals, Llc |
Use of exendin and analogs thereof to delay or prevent cardiac remodeling
|
|
EP1877121B1
(en)
|
2005-04-24 |
2015-09-23 |
Novo Nordisk A/S |
Injection device
|
|
CN101180081B
(zh)
|
2005-05-25 |
2015-08-26 |
诺沃-诺迪斯克有限公司 |
稳定的多肽制剂
|
|
TW200716679A
(en)
|
2005-05-26 |
2007-05-01 |
Bristol Myers Squibb Co |
N-terminally modified GLP-1 receptor modulators
|
|
CA2609810C
(en)
|
2005-06-06 |
2012-05-22 |
Camurus Ab |
Glp-1 analogue formulations
|
|
GB0511986D0
(en)
|
2005-06-13 |
2005-07-20 |
Imp College Innovations Ltd |
Novel compounds and their effects on feeding behaviour
|
|
PL1891105T3
(pl)
|
2005-06-13 |
2012-09-28 |
Imperial Innovations Ltd |
Analogi oksyntomoduliny i ich wpływ na zachowania żywieniowe
|
|
EP2279758B1
(en)
|
2005-06-16 |
2015-02-25 |
Nektar Therapeutics |
Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates
|
|
WO2007019331A2
(en)
|
2005-08-04 |
2007-02-15 |
Nektar Therapeutics Al, Corporation |
Conjugates of a g-csf moiety and a polymer
|
|
US8278420B2
(en)
|
2005-08-06 |
2012-10-02 |
Qinghua Wang |
Composition and method for prevention and treatment of type I diabetes
|
|
EP1922336B1
(en)
|
2005-08-11 |
2012-11-21 |
Amylin Pharmaceuticals, LLC |
Hybrid polypeptides with selectable properties
|
|
PL2347762T3
(pl)
|
2005-08-19 |
2019-09-30 |
Amylin Pharmaceuticals, Llc |
Eksendyna do leczenia cukrzycy i zmniejszania masy ciała
|
|
KR101486829B1
(ko)
|
2005-09-14 |
2015-01-29 |
맨카인드 코포레이션 |
결정질 미립자 표면에 대한 활성제의 친화력의 증가를 기반으로 하는 약물 제제의 방법
|
|
JP5072848B2
(ja)
|
2005-09-20 |
2012-11-14 |
ノバルティス アーゲー |
低血糖イベントを低減するためのｄｐｐ−ｉｖ阻害剤の使用
|
|
WO2007047834A2
(en)
|
2005-10-18 |
2007-04-26 |
Biocon Limited |
Oral peptide conjugates for metabolic diseases
|
|
WO2007047997A2
(en)
|
2005-10-19 |
2007-04-26 |
Smartcells, Inc. |
Methods for reducing the mitogenicity of lectin compositions
|
|
CA2628241C
(en)
|
2005-11-07 |
2016-02-02 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting physiological solubility and stability
|
|
US8039432B2
(en)
|
2005-11-09 |
2011-10-18 |
Conjuchem, Llc |
Method of treatment of diabetes and/or obesity with reduced nausea side effect
|
|
EP1968607B1
(en)
|
2005-12-02 |
2014-01-15 |
Nabil Habib Lab |
Treatment of cancer and other diseases
|
|
BRPI0620586A2
(pt)
|
2005-12-02 |
2011-11-16 |
Nastech Pharm Co |
formulação farmacêutica aquosa para administração intranasal e uso de uma formulação farmacêutica aquosa para elaborar um medicamento
|
|
EP1959987A2
(en)
|
2005-12-08 |
2008-08-27 |
Nastech Pharmaceutical Company Inc. |
Mucosal delivery of stabilized formulations of exendin
|
|
JP5096363B2
(ja)
|
2005-12-16 |
2012-12-12 |
ネクター セラピューティックス |
Ｇｌｐ−１のポリマ複合体
|
|
US8334257B2
(en)
|
2005-12-20 |
2012-12-18 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
|
US8841255B2
(en)
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
|
US20130172274A1
(en)
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
|
CN101400363B
(zh)
|
2006-01-18 |
2012-08-29 |
昌达生物科技公司 |
具有增强的稳定性的药物组合物
|
|
US20080071063A1
(en)
|
2006-02-03 |
2008-03-20 |
Medimmune, Inc. |
Protein Formulations
|
|
US7704953B2
(en)
|
2006-02-17 |
2010-04-27 |
Mdrna, Inc. |
Phage displayed cell binding peptides
|
|
CN101432025B
(zh)
|
2006-03-21 |
2012-04-04 |
安米林药品公司 |
肽-肽酶抑制剂结合物及其使用方法
|
|
RU2419452C2
(ru)
|
2006-04-13 |
2011-05-27 |
Ипсен Фарма С.А.С. |
ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ hGLP-1, ЭКСЕНДИНА-4 И ИХ АНАЛОГОВ
|
|
BRPI0709964A2
(pt)
|
2006-04-14 |
2011-08-02 |
Mannkind Corp |
formulações farmacêuticas contendo peptìdeo glucagon do tipo 1 (glp-1)
|
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
|
EP2029160A2
(en)
|
2006-05-12 |
2009-03-04 |
Amylin Pharmaceuticals, Inc. |
Methods to restore glycemic control
|
|
BRPI0712559A2
(pt)
|
2006-05-26 |
2012-11-20 |
Amylin Pharmaceuticals Inc |
composiÇÕes e mÉtodos para o tratamento de insuficiÊncia cardÍaca congestiva
|
|
WO2007139589A1
(en)
|
2006-05-26 |
2007-12-06 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
PL2038423T3
(pl)
|
2006-06-21 |
2013-05-31 |
Biocon Ltd |
Metoda wytwarzania biologicznie aktywnego polipeptydu insulinotropowego
|
|
WO2008038147A2
(en)
|
2006-07-05 |
2008-04-03 |
Foamix Ltd. |
Foamable vehicle comprising dicarboxylic acid or dicarboxylic acid ester and pharmaceutical compositions thereof
|
|
ATE524493T1
(de)
|
2006-07-24 |
2011-09-15 |
Biorexis Pharmaceutical Corp |
Exendin-fusionsproteine
|
|
US7928186B2
(en)
|
2006-08-02 |
2011-04-19 |
Phoenix Pharmaceuticals, Inc. |
Cell permeable bioactive peptide conjugates
|
|
EP2046284A1
(en)
|
2006-08-04 |
2009-04-15 |
Nastech Pharmaceutical Company Inc. |
Compositions for intranasal delivery of human insulin and uses thereof
|
|
EP2359808B1
(en)
|
2006-08-09 |
2013-05-22 |
Intarcia Therapeutics, Inc |
Osmotic delivery systems and piston assemblies
|
|
EP2057188B1
(en)
|
2006-08-17 |
2013-07-31 |
Amylin Pharmaceuticals, LLC |
Dpp-iv resistant gip hybrid polypeptides with selectable properties
|
|
US8497240B2
(en)
|
2006-08-17 |
2013-07-30 |
Amylin Pharmaceuticals, Llc |
DPP-IV resistant GIP hybrid polypeptides with selectable properties
|
|
US20090318353A1
(en)
*
|
2006-08-25 |
2009-12-24 |
Novo Nordisk A/S |
Acylated Exendin-4 Compounds
|
|
CN102827284B
(zh)
|
2006-11-14 |
2015-07-29 |
上海仁会生物制药股份有限公司 |
带有聚乙二醇基团的Exendin或其类似物及其制剂和用途
|
|
JP2010512399A
(ja)
|
2006-12-12 |
2010-04-22 |
アミリン・ファーマシューティカルズ，インコーポレイテッド |
医薬製剤及びその調製方法
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
SG177953A1
(en)
|
2007-01-05 |
2012-02-28 |
Univ Indiana Res & Tech Corp |
Glucagon analogs exhibiting enhanced solubility in physiological ph buffers
|
|
RU2432361C2
(ru)
|
2007-01-05 |
2011-10-27 |
КовЭкс Текнолоджиз Айэлэнд Лимитед |
Соединения агонисты рецептора глюкагоноподобного белка-1 (glp-1r)
|
|
US20090098130A1
(en)
|
2007-01-05 |
2009-04-16 |
Bradshaw Curt W |
Glucagon-like protein-1 receptor (glp-1r) agonist compounds
|
|
CN101663317A
(zh)
*
|
2007-01-05 |
2010-03-03 |
CovX科技爱尔兰有限公司 |
胰高血糖素样蛋白-1受体glp-1r激动剂化合物
|
|
WO2008098212A2
(en)
|
2007-02-08 |
2008-08-14 |
Diobex, Inc. |
Extended release formulations of glucagon and other peptides and proteins
|
|
JP6017754B2
(ja)
|
2007-02-15 |
2016-11-02 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ |
グルカゴン／ｇｌｐ−１受容体コアゴニスト
|
|
WO2008130066A1
(en)
|
2007-04-20 |
2008-10-30 |
Kang Choon Lee |
Mono modified exendin with polyethylene glycol or its derivatives and uses thereof
|
|
CN104000779A
(zh)
|
2007-04-23 |
2014-08-27 |
精达制药公司 |
促胰岛素释放肽的混悬制剂及其应用
|
|
US8236760B2
(en)
|
2007-04-27 |
2012-08-07 |
Cedars-Sinsai Medical Center |
Use of GLP-1 receptor agonists for the treatment of short bowel syndrome
|
|
US7829664B2
(en)
|
2007-06-01 |
2010-11-09 |
Boehringer Ingelheim International Gmbh |
Modified nucleotide sequence encoding glucagon-like peptide-1 (GLP-1), nucleic acid construct comprising same for production of glucagon-like peptide-1 (GLP-1), human cells comprising said construct and insulin-producing constructs, and methods of use thereof
|
|
WO2008148839A2
(en)
|
2007-06-08 |
2008-12-11 |
Ascendis Pharma As |
Long-acting polymeric prodrugs of exendin
|
|
ATE520714T1
(de)
|
2007-06-15 |
2011-09-15 |
Zealand Pharma As |
Glucagonanaloga
|
|
BRPI0813699B1
(pt)
|
2007-07-10 |
2021-06-22 |
Eli Lilly And Company |
Formulação de proteína de fusão glp-1-fc
|
|
JP2010535781A
(ja)
|
2007-08-03 |
2010-11-25 |
イーライ リリー アンド カンパニー |
肥満に対する処置
|
|
CN101366692A
(zh)
|
2007-08-15 |
2009-02-18 |
江苏豪森药业股份有限公司 |
一种稳定的艾塞那肽制剂
|
|
HRP20150330T1
(hr)
|
2007-08-30 |
2015-06-19 |
Curedm Group Holdings, Llc |
Pripravci i postupci uporabe prostaniäśnog peptida za stanice otoäśiä†a i njegovih analoga
|
|
EP2190460B1
(en)
|
2007-09-05 |
2014-12-17 |
Novo Nordisk A/S |
Peptides derivatized with a-b-c-d- and their therapeutical use
|
|
US20100256056A1
(en)
|
2007-09-07 |
2010-10-07 |
Zheng Xin Dong |
Analogues of exendin-4 and exendin-3
|
|
RU2474415C2
(ru)
|
2007-10-24 |
2013-02-10 |
Маннкайнд Корпорейшн |
Способ предотвращения побочных эффектов glp-1
|
|
US8785396B2
(en)
|
2007-10-24 |
2014-07-22 |
Mannkind Corporation |
Method and composition for treating migraines
|
|
JP5813323B2
(ja)
|
2007-10-24 |
2015-11-17 |
マンカインド コーポレイション |
活性薬剤の送達方法
|
|
CA2702289A1
(en)
|
2007-10-30 |
2009-05-07 |
Indiana University Research And Technology Corporation |
Compounds exhibiting glucagon antagonist and glp-1 agonist activity
|
|
US8981047B2
(en)
|
2007-10-30 |
2015-03-17 |
Indiana University Research And Technology Corporation |
Glucagon antagonists
|
|
DK2597103T3
(en)
|
2007-11-16 |
2017-02-13 |
Novo Nordisk As |
Stable pharmaceutical compositions comprising liraglutide and degludec
|
|
WO2009067268A1
(en)
|
2007-11-23 |
2009-05-28 |
Michael Rothkopf |
Methods of enhancing diabetes resolution
|
|
CN101444618B
(zh)
|
2007-11-26 |
2012-06-13 |
杭州九源基因工程有限公司 |
含有艾塞那肽的药物制剂
|
|
CN102026666B
(zh)
|
2007-12-11 |
2013-10-16 |
常山凯捷健生物药物研发（河北）有限公司 |
促胰岛素肽缀合物制剂
|
|
NZ586590A
(en)
|
2008-01-09 |
2012-06-29 |
Sanofi Aventis Deutschland |
Insulin analogues or derivatives having an extremely delayed time-action profile
|
|
JP2011511778A
(ja)
|
2008-01-30 |
2011-04-14 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション |
エステルに基づいたペプチドプロドラッグ
|
|
RU2010136023A
(ru)
|
2008-02-01 |
2012-03-10 |
Асцендис Фарма Ас (Dk) |
Пролекарство, содержащее саморасщепляемый линкер
|
|
US8927256B2
(en)
|
2008-02-06 |
2015-01-06 |
Biocon Limited |
Fermentation medias and processes thereof
|
|
WO2009114959A1
(zh)
|
2008-03-20 |
2009-09-24 |
中国人民解放军军事医学科学院毒物药物研究所 |
可注射用缓释药物制剂及其制备方法
|
|
WO2009125423A2
(en)
|
2008-04-07 |
2009-10-15 |
National Institute Of Immunology |
Compositions useful for the treatment of diabetes and other chronic disorder
|
|
JP2011519928A
(ja)
|
2008-05-07 |
2011-07-14 |
メリオン・リサーチ・Ｉｉｉ・リミテッド |
ペプチドの組成物及びその調製方法
|
|
US20110263496A1
(en)
|
2008-05-21 |
2011-10-27 |
Amylin Pharmaceuticals, Inc. |
Exendins to lower cholesterol and triglycerides
|
|
WO2009143014A1
(en)
|
2008-05-23 |
2009-11-26 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonist bioassays
|
|
US8485180B2
(en)
|
2008-06-13 |
2013-07-16 |
Mannkind Corporation |
Dry powder drug delivery system
|
|
TWI677355B
(zh)
|
2008-06-13 |
2019-11-21 |
美商曼凱公司 |
用於藥物傳輸之乾粉吸入器及系統
|
|
CA2728284C
(en)
|
2008-06-17 |
2019-09-10 |
Richard D. Dimarchi |
Glucagon/glp-1 receptor co-agonists
|
|
BRPI0914889A2
(pt)
|
2008-06-17 |
2015-11-24 |
Otsuka Chemical Co Ltd |
peptídeo glp-1 adicionado de cadeia oligossacarídica
|
|
BRPI0915282A2
(pt)
|
2008-06-17 |
2017-02-07 |
Univ Indiana Res & Tech Corp |
agonistas mistos baseados no gip para o tratamento de distúrbios metabólicos e obesidade
|
|
EP2307037A4
(en)
|
2008-06-17 |
2011-08-03 |
Univ Indiana Res & Tech Corp |
GLUCAGON ANALOGUE WITH IMPROVED SOLUBILITY AND STABILITY IN PHYSIOLOGICAL PH BUFFERS
|
|
CA2726894A1
(en)
|
2008-06-27 |
2009-12-30 |
Duke University |
Therapeutic agents comprising elastin-like peptides
|
|
EP2303247A4
(en)
|
2008-07-21 |
2012-08-01 |
Syneron Medical Ltd |
TRANSDERMALES SYSTEM FOR THE EXTENDED RELEASE OF INCRETINS AND INCRETIN MIMETIC PEPTIDES
|
|
WO2010013012A2
(en)
|
2008-08-01 |
2010-02-04 |
Lund University Bioscience Ab |
Novel polypeptides and uses thereof
|
|
CN101670096B
(zh)
|
2008-09-11 |
2013-01-16 |
杭州九源基因工程有限公司 |
含有艾塞那肽的药物制剂
|
|
LT2349324T
(lt)
|
2008-10-17 |
2017-12-27 |
Sanofi-Aventis Deutschland Gmbh |
Insulino ir glp-1 agonisto derinys
|
|
SI2373681T1
(sl)
|
2008-12-10 |
2017-05-31 |
Glaxosmithkline Llc Corporation Service Company |
Farmacevtski sestavki albiglutida
|
|
US8642540B2
(en)
|
2008-12-15 |
2014-02-04 |
Zealand Pharma A/S |
Glucagon analogues
|
|
PL2370461T3
(pl)
|
2008-12-15 |
2014-03-31 |
Zealand Pharma As |
Analogi glukagonu
|
|
PL2370462T3
(pl)
|
2008-12-15 |
2015-01-30 |
Zealand Pharma As |
Analogi glukagonu
|
|
MX2011006313A
(es)
|
2008-12-15 |
2011-09-27 |
Zealand Pharma As |
Analogos de glucagon.
|
|
AR074811A1
(es)
|
2008-12-19 |
2011-02-16 |
Univ Indiana Res & Tech Corp |
Profarmaco de peptido de la superfamilia de glucagon basados en amida
|
|
CN101538323B
(zh)
|
2009-01-13 |
2012-05-09 |
深圳翰宇药业股份有限公司 |
一种纯化艾塞那肽的方法
|
|
DE102009006602A1
(de)
|
2009-01-29 |
2010-08-05 |
Bayer Schering Pharma Aktiengesellschaft |
Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs
|
|
WO2010096052A1
(en)
|
2009-02-19 |
2010-08-26 |
Merck Sharp & Dohme Corp. |
Oxyntomodulin analogs
|
|
RU2487731C2
(ru)
|
2009-03-04 |
2013-07-20 |
Маннкайнд Корпорейшн |
Усовершенствованная система доставки сухого порошкообразного лекарственного средства
|
|
AU2010220255B2
(en)
|
2009-03-05 |
2014-09-04 |
Sanofi-Aventis Deutschland Gmbh |
Drug delivery device with retractable needle
|
|
US8642544B2
(en)
|
2009-04-01 |
2014-02-04 |
Amylin Pharmaceuticals, Llc |
N-terminus conformationally constrained GLP-1 receptor agonist compounds
|
|
WO2010118034A2
(en)
|
2009-04-06 |
2010-10-14 |
Board Of Regents, The University Of Texas System |
Cyclic peptide analogues for non-invasive imaging of pancreatic beta-cells
|
|
EP2423233B1
(en)
|
2009-04-22 |
2015-03-11 |
Alteogen, Inc |
In vivo half life increased fusion protein or peptide maintained by sustained in vivo release, and method for increasing in vivo half-life using same
|
|
CN101870728A
(zh)
|
2009-04-23 |
2010-10-27 |
派格生物医药(苏州)有限公司 |
新型Exendin变体及其缀合物
|
|
CN101559041B
(zh)
|
2009-05-19 |
2014-01-15 |
中国科学院过程工程研究所 |
粒径均一的多肽药物缓释微球或微囊制剂及制备方法
|
|
EP3189868B1
(en)
|
2009-05-20 |
2024-10-23 |
Sanofi-Aventis Deutschland GmbH |
A bung for drug containing cartridges in drug delivery devices comprising an electronic coding feature
|
|
CN102438679B
(zh)
|
2009-05-20 |
2016-03-09 |
赛诺菲-安万特德国有限公司 |
用于药物递送装置中药物容纳筒的塞子
|
|
WO2010138671A1
(en)
|
2009-05-28 |
2010-12-02 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonist compounds for sleep enhancement
|
|
CN102802657A
(zh)
|
2009-06-11 |
2012-11-28 |
诺沃-诺迪斯克有限公司 |
用于治疗2型糖尿病的glp-1和fgf21组合
|
|
US9150632B2
(en)
|
2009-06-16 |
2015-10-06 |
Indiana University Research And Technology Corporation |
GIP receptor-active glucagon compounds
|
|
EP2448965A4
(en)
|
2009-07-02 |
2015-02-11 |
Angiochem Inc |
MULTIMEPEPTID CONJUGATES AND ITS USES
|
|
US9156901B2
(en)
|
2009-07-13 |
2015-10-13 |
Ditte Riber |
Acylated glucagon analogues
|
|
CN101601646B
(zh)
|
2009-07-22 |
2011-03-23 |
南京凯瑞尔纳米生物技术有限公司 |
治疗糖尿病的鼻腔滴剂及其制备方法
|
|
WO2011011675A1
(en)
|
2009-07-23 |
2011-01-27 |
Zelos Therapeutics, Inc. |
Pharmaceutically acceptable formulations/compositions for peptidyl drugs
|
|
KR20120089843A
(ko)
|
2009-07-31 |
2012-08-14 |
사노피-아벤티스 도이칠란트 게엠베하 |
인슐린 링커 접합체를 포함한 프로드럭
|
|
WO2011017835A1
(en)
|
2009-08-11 |
2011-02-17 |
Nanjing University |
Preparation method of protein or peptide nanoparticles for in vivo drug delivery by unfolding and refolding
|
|
CN101993485B
(zh)
|
2009-08-20 |
2013-04-17 |
重庆富进生物医药有限公司 |
促胰岛素分泌肽类似物同源二聚体及其用途
|
|
US20120148586A1
(en)
|
2009-08-27 |
2012-06-14 |
Joyce Ching Tsu Chou |
Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders
|
|
SG10201406063XA
(en)
|
2009-09-30 |
2014-11-27 |
Glaxo Group Ltd |
Drug fusions and conjugates with extended half life
|
|
US9610329B2
(en)
|
2009-10-22 |
2017-04-04 |
Albireo Pharma, Inc. |
Stabilized glucagon solutions
|
|
DK2490708T3
(da)
|
2009-10-22 |
2013-04-15 |
Biodel Inc |
Stabiliserede glucagon-opløsninger
|
|
US20110097386A1
(en)
|
2009-10-22 |
2011-04-28 |
Biodel, Inc. |
Stabilized glucagon solutions
|
|
AU2010312655A1
(en)
|
2009-10-30 |
2012-05-03 |
Glytech, Inc. |
Glycosylated form of antigenic GLP-1 analogue
|
|
EA021983B1
(ru)
|
2009-11-02 |
2015-10-30 |
Пфайзер Инк. |
Производные диоксабицикло[3.2.1]октан-2,3,4-триола
|
|
US20120294855A1
(en)
|
2009-11-03 |
2012-11-22 |
Eli Lilly & Company |
Glp-1 receptor agonist compounds for obstructive sleep apnea
|
|
CN102711804B
(zh)
|
2009-11-13 |
2015-09-16 |
赛诺菲-安万特德国有限公司 |
包含glp-1激动剂和甲硫氨酸的药物组合物
|
|
JP5832439B2
(ja)
|
2009-11-13 |
2015-12-16 |
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
Ｇｌｐ−１アゴニスト、インスリン及びメチオニンを含む薬学的組成物
|
|
MX2012006744A
(es)
|
2009-12-15 |
2012-07-30 |
Metabolic Solutions Dev Co Llc |
Tiazolidinadionas reguladores de receptores activados por proliferador de peroxisoma (ppar) y combinaciones para el tratamiento de diabetes mellitus y otras enfermedades metabolicas.
|
|
ES2658168T3
(es)
|
2009-12-15 |
2018-03-08 |
Cirius Therapeutics, Inc. |
Sales de tiazolidinadiona ahorradoras de PPAR para el tratamiento de enfermedades metabólicas
|
|
EP3202401B1
(en)
|
2009-12-15 |
2019-10-23 |
Cirius Therapeutics, Inc. |
Ppar-sparing thiazolidinediones and combinations for the treatment of neurodegenerative diseases
|
|
WO2011084459A1
(en)
|
2009-12-15 |
2011-07-14 |
Metabolic Solutions Development Company |
Ppar-sparing thiazolidinediones and combinations for the treatment of obesity and other metabolic diseases
|
|
HUE027229T2
(en)
|
2009-12-16 |
2016-08-29 |
Novo Nordisk As |
Double acylated glp-1 derivatives
|
|
US8703701B2
(en)
|
2009-12-18 |
2014-04-22 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
|
WO2011075623A1
(en)
|
2009-12-18 |
2011-06-23 |
Latitude Pharmaceuticals, Inc. |
One - phase gel compos ition compri s ing phos pholi pids
|
|
CN101798588B
(zh)
*
|
2009-12-21 |
2015-09-09 |
上海仁会生物制药股份有限公司 |
Glp-1受体激动剂生物学活性测定方法
|
|
AR079345A1
(es)
|
2009-12-22 |
2012-01-18 |
Lilly Co Eli |
Analogo peptidico de oxintomodulina
|
|
AR079344A1
(es)
|
2009-12-22 |
2012-01-18 |
Lilly Co Eli |
Analogo peptidico de oxintomodulina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar diabetes no insulinodependiente y/u obesidad
|
|
NZ601167A
(en)
|
2010-01-20 |
2014-12-24 |
Zealand Pharma As |
Treatment of cardiac conditions
|
|
CN102834108A
(zh)
*
|
2010-01-27 |
2012-12-19 |
印第安纳大学研究及科技有限公司 |
用于治疗代谢紊乱和肥胖症的胰高血糖素拮抗剂-gip激动剂偶联物和组合物
|
|
CN102740909B
(zh)
|
2010-02-01 |
2016-05-04 |
赛诺菲-安万特德国有限公司 |
药筒保持器、给药装置和用于将药筒固定在药筒保持器中的方法
|
|
WO2011109784A1
(en)
|
2010-03-05 |
2011-09-09 |
Conjuchem, Llc |
Formulation of insulinotropic peptide conjugates
|
|
CA2793737A1
(en)
|
2010-03-24 |
2011-09-29 |
Shifamed Holdings, Llc |
Intravascular tissue disruption
|
|
WO2011117415A1
(en)
|
2010-03-26 |
2011-09-29 |
Novo Nordisk A/S |
Novel glucagon analogues
|
|
AR080592A1
(es)
*
|
2010-03-26 |
2012-04-18 |
Lilly Co Eli |
Peptido con actividad para el gip-r y glp-1-r, formulacion famaceutica que lo comprende, su uso para preparar un medicamento util para el tratamiento de diabetes mellitus y para inducir la perdida de peso
|
|
KR20130111923A
(ko)
|
2010-05-13 |
2013-10-11 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
G-단백결합 수용체 활성을 나타내는 글루카곤 슈퍼패밀리 펩티드
|
|
EP2569000B1
(en)
|
2010-05-13 |
2017-09-27 |
Indiana University Research and Technology Corporation |
Glucagon superfamily peptides exhibiting nuclear hormone receptor activity
|
|
AU2011202239C1
(en)
|
2010-05-19 |
2017-03-16 |
Sanofi |
Long-acting formulations of insulins
|
|
EP2571900A1
(en)
|
2010-05-20 |
2013-03-27 |
Glaxo Group Limited |
Improved anti-serum albumin binding variants
|
|
US8263554B2
(en)
|
2010-06-09 |
2012-09-11 |
Amylin Pharmaceuticals, Inc. |
Methods of using GLP-1 receptor agonists to treat pancreatitis
|
|
CN101891823B
(zh)
|
2010-06-11 |
2012-10-03 |
北京东方百泰生物科技有限公司 |
一种Exendin-4及其类似物融合蛋白
|
|
US8636711B2
(en)
|
2010-06-14 |
2014-01-28 |
Legacy Emanuel Hospital & Health Center |
Stabilized glucagon solutions and uses therefor
|
|
MX359281B
(es)
|
2010-06-21 |
2018-09-21 |
Mannkind Corp |
Sistema y metodos para suministrar un farmaco en polvo seco.
|
|
UY33462A
(es)
|
2010-06-23 |
2012-01-31 |
Zealand Pharma As |
Analogos de glucagon
|
|
US9234023B2
(en)
|
2010-06-24 |
2016-01-12 |
Biousian Biosystems, Inc. |
Glucagon-like peptide-1 glycopeptides
|
|
CA2796894A1
(en)
|
2010-06-24 |
2011-12-29 |
Indiana University Research And Technology Corporation |
Amide based glucagon superfamily peptide prodrugs
|
|
WO2011163473A1
(en)
|
2010-06-25 |
2011-12-29 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting enhanced solubility and stability in physiological ph buffers
|
|
WO2012012352A2
(en)
|
2010-07-19 |
2012-01-26 |
Amidebio, Llc |
Modified peptides and proteins
|
|
WO2012012460A1
(en)
|
2010-07-19 |
2012-01-26 |
Xeris Pharmaceuticals, Inc. |
Stable glucagon formulations for the treatment of hypoglycemia
|
|
BR112013002096A2
(pt)
|
2010-07-28 |
2019-09-24 |
Amylin Pharmaceuticals Inc |
compostos de agonistas de receptor glp-1 possuindo regiões estabilizadas
|
|
CN102397558B
(zh)
|
2010-09-09 |
2013-08-14 |
中国人民解放军军事医学科学院毒物药物研究所 |
Exendin-4类似物的定位聚乙二醇化修饰物及其用途
|
|
EP2438930A1
(en)
|
2010-09-17 |
2012-04-11 |
Sanofi-Aventis Deutschland GmbH |
Prodrugs comprising an exendin linker conjugate
|
|
ES2563091T3
(es)
|
2010-09-28 |
2016-03-10 |
Amylin Pharmaceuticals, Llc |
Polipéptidos modificados genéticamente que tienen duración de acción potenciada
|
|
ES2533601T3
(es)
|
2010-11-03 |
2015-04-13 |
Arecor Limited |
Nueva composición que comprende glucagón
|
|
JP6092113B2
(ja)
|
2010-11-09 |
2017-03-08 |
マンカインド コーポレイション |
セロトニン受容体アゴニストおよびジケトピペラジンを含む偏頭痛治療のための組成物
|
|
EP2460552A1
(en)
|
2010-12-06 |
2012-06-06 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device with locking arrangement for dose button
|
|
CN102552883B
(zh)
|
2010-12-09 |
2014-02-19 |
天津药物研究院 |
一种多肽复合物、药物组合物、其制备方法和应用
|
|
HRP20180425T1
(hr)
|
2010-12-16 |
2018-04-20 |
Novo Nordisk A/S |
Čvrste kompozicije koje sadrže agonist glp-1 i sol n-(8-(2-hidroksibenzoil)amino)kaprilne kiseline
|
|
WO2012088116A2
(en)
|
2010-12-22 |
2012-06-28 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting gip receptor activity
|
|
WO2012088157A2
(en)
|
2010-12-22 |
2012-06-28 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonists for islet cell transplantation
|
|
CN102532301B
(zh)
|
2010-12-31 |
2014-09-03 |
上海医药工业研究院 |
一类新型的Exendin-4类似物及其制备方法
|
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
|
CN102100906A
(zh)
|
2011-02-18 |
2011-06-22 |
深圳翰宇药业股份有限公司 |
一种艾塞那肽的药用制剂及其制备方法
|
|
KR101978527B1
(ko)
|
2011-03-10 |
2019-09-03 |
엑스에리스 파머수티클스, 인크. |
펩티드 약물의 비경구 주입을 위한 안정한 제형
|
|
CN102718858B
(zh)
|
2011-03-29 |
2014-07-02 |
天津药物研究院 |
胰高血糖素样肽-1类似物单体、二聚体及其制备方法与应用
|
|
CN106928341B
(zh)
|
2011-03-30 |
2021-06-01 |
上海仁会生物制药股份有限公司 |
定点单取代聚乙二醇化Exendin类似物及其制备方法
|
|
WO2012138941A1
(en)
|
2011-04-05 |
2012-10-11 |
Longevity Biotech, Inc. |
Compositions comprising glucagon analogs and methods of making and using the same
|
|
US9480751B2
(en)
|
2011-04-11 |
2016-11-01 |
Yeda Research And Development Co. Ltd. |
Albumin binding probes and drug conjugates thereof
|
|
WO2012150503A2
(en)
|
2011-05-03 |
2012-11-08 |
Zealand Pharma A/S |
Glu-glp-1 dual agonist signaling-selective compounds
|
|
CN102766204B
(zh)
|
2011-05-05 |
2014-10-15 |
天津药物研究院 |
胰高血糖素样肽-1突变体多肽及其制备方法和其应用
|
|
KR20240110072A
(ko)
|
2011-05-18 |
2024-07-12 |
메더리스 다이어비티즈, 엘엘씨 |
인슐린 저항성에 대한 개선된 펩티드 제약
|
|
US20140221282A1
(en)
|
2011-05-25 |
2014-08-07 |
Astrazeneca Pharmaceuticals Lp |
Long duration dual hormone conjugates
|
|
UA113626C2
(xx)
|
2011-06-02 |
2017-02-27 |
|
Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії
|
|
JP5914641B2
(ja)
|
2011-06-10 |
2016-05-11 |
ベイジン・ハンミ・ファーマシューティカル・カンパニー・リミテッドＢｅｉｊｉｎｇ Ｈａｎｍｉ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． |
グルコース依存性インスリン分泌刺激ポリペプチドのアナログ、医薬組成物及びその使用
|
|
AR086866A1
(es)
|
2011-06-10 |
2014-01-29 |
Hanmi Science Co Ltd |
Derivados de oxintomodulina y composicion farmaceutica que los comprende para el tratamiento de la obesidad
|
|
BR112013032396A2
(pt)
|
2011-06-17 |
2016-11-22 |
Halozyme Inc |
formulações estáveis de aplicações relacionadas à enzima de degradação de ácido hialurônico
|
|
PT2721062T
(pt)
|
2011-06-17 |
2019-02-12 |
Hanmi Science Co Ltd |
Conjugado que compreende oxintomodulina e um fragmento de imunoglobulina e utilização do mesmo
|
|
EP2723766A4
(en)
|
2011-06-22 |
2015-05-20 |
Univ Indiana Res & Tech Corp |
COAGONISTS OF GLUCAGON / GLP-1 RECEPTOR
|
|
PH12013502671A1
(en)
|
2011-06-22 |
2022-04-08 |
Univ Indiana Res & Tech Corp |
Glucagon/glp-1 receptor co-agonists
|
|
WO2012177929A2
(en)
|
2011-06-24 |
2012-12-27 |
Amylin Pharmaceuticals, Inc. |
Methods for treating diabetes with extended release formulations of glp-1 receptor agonists
|
|
KR101357117B1
(ko)
|
2011-06-28 |
2014-02-06 |
비앤엘델리팜 주식회사 |
폴리에틸렌글라이콜 또는 이의 유도체로 페길화된 엑센딘-4 유사체, 이의 제조방법 및 이를 유효성분으로 함유하는 당뇨병 예방 또는 치료용 약학적 조성물
|
|
EP2729493B1
(en)
|
2011-07-04 |
2020-06-10 |
IP2IPO Innovations Limited |
Novel compounds and their effects on feeding behaviour
|
|
JP6006309B2
(ja)
|
2011-07-08 |
2016-10-12 |
アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc |
作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド
|
|
BR112014002986A2
(pt)
|
2011-08-10 |
2017-06-13 |
Adocia |
composição sob a forma de uma solução injetável, e formulação de dose única
|
|
JP6169079B2
(ja)
|
2011-08-24 |
2017-07-26 |
フェーズバイオ ファーマシューティカルズ，インコーポレイテッド |
徐放のための活性剤の製剤
|
|
CN103189389B
(zh)
|
2011-09-03 |
2017-08-11 |
深圳市健元医药科技有限公司 |
新的glp‑ⅰ类似物及其制备方法和用途
|
|
CN104093735B
(zh)
|
2011-09-23 |
2018-07-06 |
诺沃—诺迪斯克有限公司 |
新的胰高血糖素类似物
|
|
CA2851690C
(en)
|
2011-10-28 |
2022-07-26 |
Sanofi-Aventis Deutschland Gmbh |
Treatment protocol of diabetes type 2
|
|
CN102363633B
(zh)
|
2011-11-16 |
2013-11-20 |
天津拓飞生物科技有限公司 |
胰高血糖素样肽-1突变体多肽及其制备方法、药物组合物和其应用
|
|
US8859491B2
(en)
|
2011-11-17 |
2014-10-14 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting glucocorticoid receptor activity
|
|
SG11201401597TA
(en)
|
2011-11-29 |
2014-05-29 |
Jurox Pty Ltd |
Methods of preserving injectable pharmaceutical compositions comprising a cyclodextrin and a hydrophobic drug
|
|
SI2791160T1
(sl)
|
2011-12-16 |
2022-07-29 |
Modernatx, Inc. |
Sestave modificirane MRNA
|
|
KR101640697B1
(ko)
|
2011-12-22 |
2016-07-18 |
화이자 인코포레이티드 |
항당뇨병 화합물
|
|
EA201490982A1
(ru)
|
2011-12-23 |
2015-01-30 |
Зилэнд Фарма А/С |
Аналоги глюкагона
|
|
CN104159570A
(zh)
|
2011-12-29 |
2014-11-19 |
陈献 |
稳定的胰高血糖素纳米乳液
|
|
WO2013104861A1
(fr)
|
2012-01-09 |
2013-07-18 |
Adocia |
Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide substitue
|
|
WO2013148871A1
(en)
|
2012-03-28 |
2013-10-03 |
Amylin Pharmaceuticals, Llc |
Engineered polypeptides
|
|
HK1208155A1
(en)
|
2012-03-28 |
2016-02-26 |
Amylin Pharmaceuticals, Llc |
Transmucosal delivery of engineered polypeptides
|
|
AU2013243952A1
(en)
|
2012-04-02 |
2014-10-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
HK1206612A1
(en)
|
2012-04-02 |
2016-01-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of secreted proteins
|
|
CN102649947A
(zh)
|
2012-04-20 |
2012-08-29 |
无锡和邦生物科技有限公司 |
一种用于测定glp-1及其功能类似物生物活性的细胞株及其应用
|
|
US20150111246A1
(en)
|
2012-04-24 |
2015-04-23 |
Astrazeneca Pharmaceuticals Lp |
Site-specific enzymatic modification of exendins and analogs thereof
|
|
US20130289241A1
(en)
|
2012-04-26 |
2013-10-31 |
Shanghai Ambiopharm, Inc. |
Method for preparing exenatide
|
|
US8901484B2
(en)
|
2012-04-27 |
2014-12-02 |
Sanofi-Aventis Deutschland Gmbh |
Quantification of impurities for release testing of peptide products
|
|
WO2013182217A1
(en)
|
2012-04-27 |
2013-12-12 |
Sanofi-Aventis Deutschland Gmbh |
Quantification of impurities for release testing of peptide products
|
|
IN2014MN02304A
(OSRAM)
*
|
2012-05-03 |
2015-08-07 |
Zealand Pharma As |
|
|
CA2872315A1
(en)
|
2012-05-03 |
2013-11-07 |
Zealand Pharma A/S |
Glucagon-like-peptide-2 (glp-2) analogues
|
|
EP2664374A1
(en)
|
2012-05-15 |
2013-11-20 |
F. Hoffmann-La Roche AG |
Lysin-glutamic acid dipeptide derivatives
|
|
CN103421094A
(zh)
|
2012-05-24 |
2013-12-04 |
上海医药工业研究院 |
一种具有epo类似活性的多肽化合物
|
|
US20150174209A1
(en)
|
2012-05-25 |
2015-06-25 |
Amylin Pharmaceuticals. Llc |
Insulin-pramlintide compositions and methods for making and using them
|
|
CA2875743A1
(en)
|
2012-06-14 |
2013-12-19 |
Sanofi |
Exendin-4 peptide analogues
|
|
PL2864350T3
(pl)
|
2012-06-21 |
2019-01-31 |
Indiana University Research And Technology Corporation |
Analogi glukagonu wykazujące aktywność wobec receptora GIP
|
|
US9340600B2
(en)
|
2012-06-21 |
2016-05-17 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting GIP receptor activity
|
|
CA2878457C
(en)
|
2012-07-12 |
2021-01-19 |
Mannkind Corporation |
Dry powder drug delivery systems and methods
|
|
CN109456400A
(zh)
|
2012-07-23 |
2019-03-12 |
西兰制药公司 |
胰高血糖素类似物
|
|
AR094821A1
(es)
|
2012-07-25 |
2015-09-02 |
Hanmi Pharm Ind Co Ltd |
Formulación líquida de un conjugado de péptido insulinotrópico de acción prolongada
|
|
KR101968344B1
(ko)
|
2012-07-25 |
2019-04-12 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물
|
|
AR092862A1
(es)
|
2012-07-25 |
2015-05-06 |
Hanmi Pharm Ind Co Ltd |
Formulacion liquida de insulina de accion prolongada y un peptido insulinotropico y metodo de preparacion
|
|
US20150224176A1
(en)
|
2012-08-14 |
2015-08-13 |
Wockhardt Limited |
Pharmaceutical microparticulate compositions of polypeptides
|
|
US20150258198A1
(en)
|
2012-08-14 |
2015-09-17 |
Wockhardt Limited |
Pharmaceutical microparticulate compositions of polypeptides
|
|
CN102816244A
(zh)
|
2012-08-23 |
2012-12-12 |
无锡和邦生物科技有限公司 |
一种Exendin-4肽与人血清白蛋白HSA的融合蛋白及其制备方法
|
|
CN102827270A
(zh)
|
2012-09-13 |
2012-12-19 |
无锡和邦生物科技有限公司 |
一种聚乙二醇化艾塞那肽衍生物及其用途
|
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
|
US9546205B2
(en)
|
2012-09-17 |
2017-01-17 |
Imperial Innovations Limited |
Peptide analogues of glucagon and GLP1
|
|
AR092873A1
(es)
|
2012-09-26 |
2015-05-06 |
Cadila Healthcare Ltd |
Peptidos como agonistas triples de los receptores de gip, glp-1 y glugagon
|
|
UA116217C2
(uk)
|
2012-10-09 |
2018-02-26 |
Санофі |
Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
|
|
KR101993393B1
(ko)
|
2012-11-06 |
2019-10-01 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 당뇨병 또는 비만성 당뇨병 치료용 조성물
|
|
KR102311517B1
(ko)
|
2012-11-06 |
2021-10-14 |
한미약품 주식회사 |
옥신토모듈린과 면역글로불린 단편을 포함하는 단백질 결합체의 액상 제제
|
|
JP6525456B2
(ja)
|
2012-11-20 |
2019-06-05 |
メデリス ダイアビーティーズ，エルエルシー |
インスリン抵抗性のための改善されたペプチド製剤
|
|
TWI617574B
(zh)
|
2012-12-11 |
2018-03-11 |
梅迪繆思有限公司 |
用於治療肥胖之升糖素與ｇｌｐ－１共促效劑
|
|
SG10201705097PA
(en)
*
|
2012-12-21 |
2017-07-28 |
Sanofi Sa |
Functionalized exendin-4 derivatives
|
|
CN103908657A
(zh)
|
2012-12-31 |
2014-07-09 |
复旦大学附属华山医院 |
胰升糖素样肽-1类似物在制备眼科疾病药物中的用途
|
|
EP2968581A1
(en)
|
2013-03-14 |
2016-01-20 |
Medimmune Limited |
Pegylated glucagon and glp-1 co-agonists for the treatment of obesity
|
|
US20160024169A1
(en)
|
2013-03-14 |
2016-01-28 |
Indiana University Research And Technology Corporation |
Insulin-incretin conjugates
|
|
US20160058881A1
(en)
|
2013-03-15 |
2016-03-03 |
Indiana University Research And Technology Corporation |
Prodrugs with prolonged action
|
|
WO2014170496A1
(en)
|
2013-04-18 |
2014-10-23 |
Novo Nordisk A/S |
Stable, protracted glp-1/glucagon receptor co-agonists for medical use
|
|
JP2014227368A
(ja)
|
2013-05-21 |
2014-12-08 |
国立大学法人帯広畜産大学 |
糖尿病および高血糖状態の処置のためのグルカゴンアナログ
|
|
CN103304660B
(zh)
|
2013-07-12 |
2016-08-10 |
上海昂博生物技术有限公司 |
一种利拉鲁肽的合成方法
|
|
CN103405753B
(zh)
|
2013-08-13 |
2016-05-11 |
上海仁会生物制药股份有限公司 |
稳定的促胰岛素分泌肽水针药物组合物
|
|
RS57632B1
(sr)
|
2013-10-17 |
2018-11-30 |
Zealand Pharma As |
Acilovani analozi glukagona
|
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
|
JP2017503474A
(ja)
|
2013-11-06 |
2017-02-02 |
ジーランド ファーマ アクティーゼルスカブ |
グルカゴン−ｇｌｐ−１−ｇｉｐトリプルアゴニスト化合物
|
|
WO2015086728A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
|
|
TW201609797A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
雙重ｇｌｐ－１／升糖素受體促效劑
|
|
TW201609796A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
非醯化之艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物
|
|
TW201609800A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
做為雙重ｇｌｐ－１／升糖素受體促效劑之艾塞那肽－４胜肽類似物
|
|
TW201609798A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
Ｅｘｅｎｄｉｎ－４胜肽類似物
|
|
EP3080154B1
(en)
|
2013-12-13 |
2018-02-07 |
Sanofi |
Dual glp-1/gip receptor agonists
|
|
CN103665148B
(zh)
|
2013-12-17 |
2016-05-11 |
中国药科大学 |
一种可口服给药的降糖多肽及其制法和用途
|
|
CN103980358B
(zh)
|
2014-01-03 |
2016-08-31 |
杭州阿诺生物医药科技股份有限公司 |
一种制备利拉鲁肽的方法
|
|
US9895424B2
(en)
|
2014-01-09 |
2018-02-20 |
Sanofi |
Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives
|
|
EP3091995B1
(en)
|
2014-01-09 |
2024-03-20 |
Sanofi |
Stabilized pharmaceutical formulations of insulin aspart
|
|
GB201404002D0
(en)
|
2014-03-06 |
2014-04-23 |
Imp Innovations Ltd |
Novel compounds
|
|
TW201625668A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物
|
|
TW201625670A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑
|
|
TW201625669A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
|
|
US9932381B2
(en)
|
2014-06-18 |
2018-04-03 |
Sanofi |
Exendin-4 derivatives as selective glucagon receptor agonists
|
|
CN106519015B
(zh)
|
2014-09-23 |
2020-04-17 |
深圳市图微安创科技开发有限公司 |
胃泌酸调节素类似物
|
|
WO2016055610A1
(en)
|
2014-10-10 |
2016-04-14 |
Novo Nordisk A/S |
Stable glp-1 based glp-1/glucagon receptor co-agonists
|
|
CA3093383A1
(en)
|
2014-10-24 |
2016-04-28 |
Merck Sharp & Dohme Corp. |
Co-agonists of the glucagon and glp-1 receptors
|
|
WO2016198624A1
(en)
|
2015-06-12 |
2016-12-15 |
Sanofi |
Exendin-4 derivatives as trigonal glp-1/glucagon/gip receptor agonists
|
|
WO2016198604A1
(en)
|
2015-06-12 |
2016-12-15 |
Sanofi |
Exendin-4 derivatives as dual glp-1 /glucagon receptor agonists
|
|
AR105284A1
(es)
|
2015-07-10 |
2017-09-20 |
Sanofi Sa |
Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
|