PL2347762T3 - Eksendyna do leczenia cukrzycy i zmniejszania masy ciała - Google Patents
Eksendyna do leczenia cukrzycy i zmniejszania masy ciałaInfo
- Publication number
- PL2347762T3 PL2347762T3 PL10016112T PL10016112T PL2347762T3 PL 2347762 T3 PL2347762 T3 PL 2347762T3 PL 10016112 T PL10016112 T PL 10016112T PL 10016112 T PL10016112 T PL 10016112T PL 2347762 T3 PL2347762 T3 PL 2347762T3
- Authority
- PL
- Poland
- Prior art keywords
- exendin
- body weight
- treating diabetes
- reducing body
- reducing
- Prior art date
Links
- 230000037396 body weight Effects 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70960405P | 2005-08-19 | 2005-08-19 | |
| US77921606P | 2006-03-03 | 2006-03-03 | |
| PCT/US2006/032354 WO2007024700A2 (en) | 2005-08-19 | 2006-08-18 | Exendin for treating diabetes and reducing body weight |
| EP10016112.4A EP2347762B1 (en) | 2005-08-19 | 2006-08-18 | Exendin for treating diabetes and reducing body weight |
| EP06801867.0A EP1971362B1 (en) | 2005-08-19 | 2006-08-18 | Exendin for treating diabetes and reducing body weight |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2347762T3 true PL2347762T3 (pl) | 2019-09-30 |
Family
ID=37772212
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10016112T PL2347762T3 (pl) | 2005-08-19 | 2006-08-18 | Eksendyna do leczenia cukrzycy i zmniejszania masy ciała |
| PL19163698.4T PL3524261T3 (pl) | 2005-08-19 | 2006-08-18 | Eksendyna do stosowania w leczeniu cukrzycy i zmniejszania masy ciała |
| PL06801867T PL1971362T3 (pl) | 2005-08-19 | 2006-08-18 | Eksendyna do leczenia cukrzycy i zmniejszania masy ciała |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19163698.4T PL3524261T3 (pl) | 2005-08-19 | 2006-08-18 | Eksendyna do stosowania w leczeniu cukrzycy i zmniejszania masy ciała |
| PL06801867T PL1971362T3 (pl) | 2005-08-19 | 2006-08-18 | Eksendyna do leczenia cukrzycy i zmniejszania masy ciała |
Country Status (25)
| Country | Link |
|---|---|
| US (7) | US20090239796A1 (pl) |
| EP (3) | EP3524261B1 (pl) |
| JP (2) | JP5693817B2 (pl) |
| KR (1) | KR101059279B1 (pl) |
| CN (1) | CN105056211A (pl) |
| AU (2) | AU2006283517B2 (pl) |
| BR (1) | BRPI0615358B8 (pl) |
| CA (1) | CA2619426C (pl) |
| CY (1) | CY1122010T1 (pl) |
| DK (3) | DK1971362T3 (pl) |
| ES (3) | ES2968190T3 (pl) |
| FI (1) | FI3524261T3 (pl) |
| HR (1) | HRP20150186T1 (pl) |
| HU (2) | HUE064811T2 (pl) |
| IL (2) | IL189607A (pl) |
| LT (2) | LT2347762T (pl) |
| MX (1) | MX2008002370A (pl) |
| NZ (2) | NZ593461A (pl) |
| PL (3) | PL2347762T3 (pl) |
| PT (3) | PT2347762T (pl) |
| RS (1) | RS53814B1 (pl) |
| RU (1) | RU2421237C2 (pl) |
| SG (1) | SG184730A1 (pl) |
| SI (3) | SI2347762T1 (pl) |
| WO (1) | WO2007024700A2 (pl) |
Families Citing this family (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| RU2350327C2 (ru) | 2003-04-29 | 2009-03-27 | Ориксиджен Серапьютикс, Инкорпорэйтд | Составы, вызывающие потерю веса |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| DK1971362T3 (en) | 2005-08-19 | 2015-01-26 | Amylin Pharmaceuticals Llc | Exendin for treating diabetes and reducing body weight |
| WO2007140416A2 (en) | 2006-05-30 | 2007-12-06 | Intarcia Therapeutics, Inc. | Two-piece, internal-channel osmotic delivery system flow modulator |
| PT2359808E (pt) | 2006-08-09 | 2013-08-28 | Intarcia Therapeutics Inc | Sistemas de entrega osmótica e montagens de pistão |
| ES2402172T3 (es) | 2007-04-23 | 2013-04-29 | Intarcia Therapeutics, Inc | Formulación en suspensión de péptidos insulinotrópicos y usos de los mismos |
| JP2009019027A (ja) * | 2007-07-16 | 2009-01-29 | Hanmi Pharmaceutical Co Ltd | アミノ末端のアミノ酸が変異したインスリン分泌ペプチド誘導体 |
| WO2009102467A2 (en) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| US20110263496A1 (en) * | 2008-05-21 | 2011-10-27 | Amylin Pharmaceuticals, Inc. | Exendins to lower cholesterol and triglycerides |
| EP2303025A4 (en) | 2008-05-30 | 2012-07-04 | Orexigen Therapeutics Inc | METHOD FOR TREATING DIGITAL FAT SWITCHES |
| EP2341905B2 (en) | 2008-09-04 | 2023-09-13 | Amylin Pharmaceuticals, LLC | Sustained release formulations using non-aqueous carriers |
| EP3228320B1 (de) | 2008-10-17 | 2019-12-18 | Sanofi-Aventis Deutschland GmbH | Kombination von einem insulin und einem glp-1-agonisten |
| EP2435061A4 (en) | 2009-05-28 | 2013-03-27 | Amylin Pharmaceuticals Inc | DAMPING GLP-1 RECEPTOR AGONIST COMPOUNDS |
| JP5854513B2 (ja) | 2009-08-03 | 2016-02-09 | インキューブ ラブズ, エルエルシー | 腸管内でインクレチン生産を刺激するための嚥下可能カプセルおよび方法 |
| EP3735944A1 (en) | 2009-09-28 | 2020-11-11 | Intarcia Therapeutics, Inc. | Rapid establishment and/or termination of substantial steady-state drug delivery |
| US20120294855A1 (en) | 2009-11-03 | 2012-11-22 | Eli Lilly & Company | Glp-1 receptor agonist compounds for obstructive sleep apnea |
| PE20121316A1 (es) | 2009-11-13 | 2012-10-05 | Sanofi Aventis Deutschland | Composicion farmaceutica que comprende un agonista de glp-1 y metionina |
| PT2554183T (pt) | 2009-11-13 | 2018-07-09 | Sanofi Aventis Deutschland | Composição farmacêutica que compreende um agonista de glp-1, uma insulina e metionina |
| US8759284B2 (en) | 2009-12-24 | 2014-06-24 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| EP3659604A1 (en) | 2010-01-11 | 2020-06-03 | Nalpropion Pharmaceuticals, Inc. | Methods of providing weight loss therapy in patients with major depression |
| EP2389945A1 (en) * | 2010-05-28 | 2011-11-30 | Sanofi-Aventis Deutschland GmbH | Pharmaceutical composition comprising AVE0010 and insulin glargine |
| US20140148384A1 (en) | 2010-08-30 | 2014-05-29 | Sanofi-Aventis Deutschland Gmbh | Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2 |
| WO2012054817A1 (en) * | 2010-10-22 | 2012-04-26 | Mitokine Bioscience, Llc | Delaying and/ or treating hyperglycemia, including diabetes, with poly(alkyl carboxylic acids) |
| MX345501B (es) | 2010-12-16 | 2017-02-02 | Novo Nordisk As | Composiciones solidas que comprenden agonista de glp-1 y sal del acido n-(8-(2-hidroxibenzoil)amino)caprilico. |
| US9283179B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402807B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9629799B2 (en) | 2010-12-23 | 2017-04-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8969293B2 (en) | 2010-12-23 | 2015-03-03 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8846040B2 (en) | 2010-12-23 | 2014-09-30 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9284367B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8809271B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising liraglutide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| EP2668951B9 (en) | 2011-01-25 | 2017-03-15 | Viviabiotech, S.L. | 1,2,4-oxadiazole derivatives as drugs modulating the glp-1 peptide receptor |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| KR101972836B1 (ko) | 2011-04-12 | 2019-04-29 | 노보 노르디스크 에이/에스 | 이중 아실화된 glp-1 유도체 |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| US9944687B2 (en) | 2011-07-04 | 2018-04-17 | Imperial Innovations Limited | Compounds and their effects on feeding behaviour |
| CN108079281A (zh) | 2011-08-29 | 2018-05-29 | 赛诺菲-安万特德国有限公司 | 用于2型糖尿病患者中的血糖控制的药物组合 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| WO2013063049A1 (en) * | 2011-10-24 | 2013-05-02 | University Of Central Florida Research Foundation, Inc. | Orally-administered plastid expressed cholera toxin b subunit-exendin 4 as treatment for type 2 diabetes |
| HRP20190489T1 (hr) | 2012-03-22 | 2019-05-03 | Novo Nordisk A/S | Pripravci koji sadrže sredstvo za unošenje i njihova priprava |
| EP2827885B1 (en) | 2012-03-22 | 2018-08-15 | Novo Nordisk A/S | Compositions of glp-1 peptides and preparation thereof |
| PT3730132T (pt) | 2012-06-06 | 2022-08-16 | Nalpropion Pharmaceuticals Llc | Composição para utilização num método de tratamento de excesso de peso e obesidade em doentes com alto risco cardiovascular |
| US9993430B2 (en) | 2012-06-20 | 2018-06-12 | Novo Nordisk A/S | Tablet formulation comprising semaglutide and a delivery agent |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| SG10201705097PA (en) | 2012-12-21 | 2017-07-28 | Sanofi Sa | Functionalized exendin-4 derivatives |
| WO2014139182A1 (en) | 2013-03-15 | 2014-09-18 | Shenzhen Hightide Biopharmaceutical, Ltd. | Compositions and methods of using islet neogenesis peptides and analogs thereof |
| SMT201800492T1 (it) | 2013-05-02 | 2018-11-09 | Novo Nordisk As | Dosaggio orale di composti di glp-1 |
| WO2015086730A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Non-acylated exendin-4 peptide analogues |
| TW201609795A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 作為雙重glp-1/gip受體促效劑的艾塞那肽-4(exendin-4)胜肽類似物 |
| EP3080149A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Dual glp-1/glucagon receptor agonists |
| WO2015086729A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/gip receptor agonists |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| WO2015169789A1 (en) * | 2014-05-07 | 2015-11-12 | Novo Nordisk A/S | Treatment of diabetes type 1 using glp-1 and anti-il-21 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| RU2573933C1 (ru) * | 2014-08-21 | 2016-01-27 | Дафот Энтерпрайсис Лимитед | Пептид для лечения сахарного диабета 2-го типа и его осложнений |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| WO2016070117A1 (en) | 2014-11-02 | 2016-05-06 | Nano Precision Medical, Inc. | Implantable medical devices for extended release of therapeutic agents |
| TWI758239B (zh) | 2014-12-12 | 2022-03-21 | 德商賽諾菲阿凡提斯德意志有限公司 | 甘精胰島素/利司那肽固定比率配製劑 |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
| CA2981507A1 (en) | 2015-04-07 | 2016-10-13 | Intercept Pharmaceuticals, Inc. | Pharmaceutical compositions for combination therapy |
| RS62368B1 (sr) | 2015-05-22 | 2021-10-29 | Univ Leland Stanford Junior | Lečenje postbarijatrijske hipoglikemije eksendinom(9-39) |
| KR101661332B1 (ko) * | 2015-05-28 | 2016-09-29 | (의료)길의료재단 | 글루카곤 유사 펩타이드-1 수용체 항진제를 포함하는 근감소증 치료용 약학 조성물 |
| KR102650751B1 (ko) | 2015-06-03 | 2024-03-22 | 인타르시아 세라퓨틱스 인코포레이티드 | 임플란트 배치 및 제거 시스템들 |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| AR105284A1 (es) | 2015-07-10 | 2017-09-20 | Sanofi Sa | Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón |
| US20170098040A1 (en) * | 2015-10-06 | 2017-04-06 | Scale Down | Weight management system and method |
| US10653753B2 (en) | 2016-03-04 | 2020-05-19 | Eiger Biopharmaceuticals, Inc. | Treatment of hyperinsulinemic hypoglycemia with exendin-4 derivatives |
| US11207415B2 (en) | 2016-04-15 | 2021-12-28 | Syracuse University | Peptide drug improvement using vitamin B12 and haptocorrin binding substrate conjugates |
| CN109310743A (zh) | 2016-05-16 | 2019-02-05 | 因塔西亚制药公司 | 胰高血糖素受体选择性多肽及其使用方法 |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| US20190224122A1 (en) | 2016-09-23 | 2019-07-25 | Delpor, Inc. | Stable compositions for incretin mimetic compounds |
| BR112019010236A2 (pt) | 2016-11-21 | 2019-08-20 | Eiger Biopharmaceuticals, Inc | formulações tamponadas de exendina (9-39) |
| AU2018206539A1 (en) | 2017-01-03 | 2019-07-18 | Intarcia Therapeutics, Inc. | Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
| WO2018136505A1 (en) | 2017-01-17 | 2018-07-26 | Wayne State University | Zwitterionic polymer-insulin compositions and related methods |
| WO2018165462A1 (en) | 2017-03-08 | 2018-09-13 | Intarcia Therapeutics, Inc | Apparatus and methods for administration of a nauseogenic compound from a drug delivery device |
| EP3609577B1 (en) * | 2017-04-14 | 2024-09-11 | University of Massachusetts | Brown fat-selective adipokines |
| EP3639840B1 (en) | 2017-05-11 | 2025-07-16 | Shenzhen Hightide Biopharmaceutical Ltd. | Ingap-pp and hip peptides for use in treatment of acute pancreatitis |
| EP4299118A3 (en) | 2018-02-02 | 2024-04-10 | Novo Nordisk A/S | Solid compositions comprising a glp-1 agonist, a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant |
| WO2019240755A1 (en) * | 2018-06-11 | 2019-12-19 | Wellesley Pharmaceuticals, Llc | Pharmaceutical compositions and methods for weight loss |
| SG11202103636TA (en) * | 2018-10-12 | 2021-05-28 | Miraki Innovation Think Tank Llc | Cold solution for fat reduction |
| EP3875476A4 (en) * | 2018-10-30 | 2022-08-24 | Jianning Liu | GLP-1 POLYPEPTIDE WITH GLP-1 RECEPTOR AGONIST ACTIVITY AND USES THEREOF |
| US20230201174A1 (en) | 2020-04-22 | 2023-06-29 | Bayer Aktiengesellschaft | Combination of finerenone and a sglt2 inhibitor for the treatment and/or prevention of cardiovascular and/or renal diseases |
| KR102556528B1 (ko) * | 2020-12-08 | 2023-07-17 | 경희대학교 산학협력단 | 대사성 질환 예방, 개선 또는 치료용 조성물 |
| CN119770624B (zh) * | 2025-03-13 | 2025-07-08 | 上海水大技术转移有限公司 | 一种抗冻蛋白在减肥降糖中的应用 |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US386998A (en) | 1888-07-31 | Boiler | ||
| US3490597A (en) | 1966-07-22 | 1970-01-20 | Purolator Products Inc | Cover plate for spin-on-filter |
| JP2989002B2 (ja) | 1988-12-22 | 1999-12-13 | キリン―アムジエン・インコーポレーテツド | 化学修飾顆粒球コロニー刺激因子 |
| US5445781A (en) | 1991-08-28 | 1995-08-29 | Centro Sviluppo Settori Impiego S.R.L. | Process for the injection molding of non-precatalyzed polymerizable resins at high-pressure and flow |
| US5509305A (en) | 1992-02-12 | 1996-04-23 | Daniel Industries, Inc. | Closely coupled, dual turbine volumetric flow meter |
| US5656297A (en) | 1992-03-12 | 1997-08-12 | Alkermes Controlled Therapeutics, Incorporated | Modulated release from biocompatible polymers |
| US6284727B1 (en) | 1993-04-07 | 2001-09-04 | Scios, Inc. | Prolonged delivery of peptides |
| US5424286A (en) | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
| GB2282891B (en) | 1993-10-13 | 1997-09-03 | Tokai Rika Co Ltd | Acceleration detecting apparatus |
| EP2275089A1 (en) | 1993-11-19 | 2011-01-19 | Alkermes Controlled Therapeutics, Inc. | Preparation of biodegradable microparticles containing a biologically active agent |
| US5650173A (en) | 1993-11-19 | 1997-07-22 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of biodegradable microparticles containing a biologically active agent |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| ES2359031T3 (es) | 1996-08-08 | 2011-05-17 | Amylin Pharmaceuticals, Inc. | Composición farmacéutica que comprende un péptido de exendina-4. |
| JP4798814B2 (ja) | 1997-01-07 | 2011-10-19 | アミリン・ファーマシューティカルズ,インコーポレイテッド | 食物摂取低減用のエキセンジンおよびそのアゴニストの使用 |
| EP1512395A1 (en) | 1997-07-18 | 2005-03-09 | Azopax Therapeutics LLC | Biodegradable macromers for the controlled release of biologically active substances |
| US20030087820A1 (en) | 1999-01-14 | 2003-05-08 | Young Andrew A. | Novel exendin agonist formulations and methods of administration thereof |
| EP1140145B2 (en) | 1999-01-14 | 2019-05-15 | Amylin Pharmaceuticals, LLC | Novel exendin agonist formulations and methods of administration thereof |
| DE60032331T2 (de) | 1999-01-14 | 2007-06-21 | Amylin Pharmaceuticals, Inc., San Diego | Exendine zur glucagon suppression |
| CN1372570A (zh) * | 1999-04-30 | 2002-10-02 | 安米林药品公司 | 修饰的exendin和exendin激动剂 |
| US6924264B1 (en) * | 1999-04-30 | 2005-08-02 | Amylin Pharmaceuticals, Inc. | Modified exendins and exendin agonists |
| US6162260A (en) | 1999-05-24 | 2000-12-19 | Novo Nordisk Biochem North America, Inc. | Single-bath biopreparation and dyeing of textiles |
| JP2003519667A (ja) | 2000-01-10 | 2003-06-24 | アミリン・ファーマシューティカルズ,インコーポレイテッド | トリグリセリドレベルの調節および脂質異常血症の治療のためのエキセンジンおよびそのアゴニストの使用 |
| US6602997B2 (en) | 2000-04-27 | 2003-08-05 | Shin-Etsu Bio, Inc. | Whole cell and cell-debris polysaccharide |
| US6495164B1 (en) | 2000-05-25 | 2002-12-17 | Alkermes Controlled Therapeutics, Inc. I | Preparation of injectable suspensions having improved injectability |
| US6479065B2 (en) | 2000-08-10 | 2002-11-12 | Alkermes Controlled Therapeutics, Inc. | Process for the preparation of polymer-based sustained release compositions |
| US6824822B2 (en) | 2001-08-31 | 2004-11-30 | Alkermes Controlled Therapeutics Inc. Ii | Residual solvent extraction method and microparticles produced thereby |
| EP1390061A2 (en) | 2000-12-13 | 2004-02-25 | Eli Lilly And Company | Chronic treatment regimen using glucagon-like insulinotropic peptides |
| US6819912B2 (en) | 2001-11-05 | 2004-11-16 | Freescale Semiconductor, Inc. | Variable frequency switching amplifier and method therefor |
| US7092459B2 (en) | 2001-11-08 | 2006-08-15 | Qualcomm, Incorporated | Frequency tracking using pilot and non-pilot symbols |
| GB0206792D0 (en) | 2002-03-22 | 2002-05-01 | Leuven K U Res & Dev | Normoglycemia |
| JP2006505562A (ja) | 2002-10-17 | 2006-02-16 | アルカーメス コントロールド セラピューティクス,インコーポレイテッド | 持続放出組成物の放出プロフィールの調節方法 |
| WO2004035762A2 (en) | 2002-10-17 | 2004-04-29 | Alkermes Controlled Therapeutics, Inc. Ii | Microencapsulation and sustained release of biologically active polypeptides |
| US7790681B2 (en) | 2002-12-17 | 2010-09-07 | Amylin Pharmaceuticals, Inc. | Treatment of cardiac arrhythmias with GLP-1 receptor ligands |
| WO2005040195A2 (en) | 2003-10-24 | 2005-05-06 | Azopax Therapeutics Llc | Formulation of exendins |
| WO2005041873A2 (en) * | 2003-10-24 | 2005-05-12 | Azopax Therapeutics Llc | Formulation of exendin-4 |
| WO2005058252A2 (en) | 2003-12-16 | 2005-06-30 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Glp-1 pharmaceutical compositions |
| US7456254B2 (en) * | 2004-04-15 | 2008-11-25 | Alkermes, Inc. | Polymer-based sustained release device |
| WO2005110425A1 (en) * | 2004-04-15 | 2005-11-24 | Alkermes, Inc. | Polymer-based sustained release device |
| NZ551196A (en) | 2004-05-14 | 2010-08-27 | Emisphere Tech Inc | Compounds and compositions for delivering active agents |
| EP1765310B1 (en) | 2004-05-28 | 2015-10-28 | Oryxe | A mixture for transdermal delivery of low and high molecular weight compounds |
| KR101231856B1 (ko) | 2004-08-12 | 2013-02-08 | 큐피에스 엘엘씨 | 생물학적 활성 화합물의 제어 방출 전달용 약학 조성물 |
| US20060034889A1 (en) | 2004-08-16 | 2006-02-16 | Macromed, Inc. | Biodegradable diblock copolymers having reverse thermal gelation properties and methods of use thereof |
| US7442682B2 (en) | 2004-10-19 | 2008-10-28 | Nitto Denko Corporation | Transepithelial delivery of peptides with incretin hormone activities |
| DK1971362T3 (en) | 2005-08-19 | 2015-01-26 | Amylin Pharmaceuticals Llc | Exendin for treating diabetes and reducing body weight |
| US8389472B2 (en) | 2005-08-19 | 2013-03-05 | Amylin Pharmaceuticals, Llc | Exendin-4 to treat nonalcoholic steatohepatitis and nonalcoholic fatty liver disease |
| US7512298B2 (en) | 2006-12-01 | 2009-03-31 | 3M Innovative Properties Company | Optical sensing methods |
| IT1402944B1 (it) | 2010-12-15 | 2013-09-27 | Sarong Spa | Capsula per bevande e relativa macchina per utilizzare detta capsula |
| US11638099B2 (en) | 2011-12-23 | 2023-04-25 | Shenzhen Shokz Co., Ltd. | Bone conduction speaker and compound vibration device thereof |
| JP6226510B2 (ja) | 2012-01-27 | 2017-11-08 | キヤノン株式会社 | 画像処理システム、処理方法及びプログラム |
| ITMI20130325A1 (it) | 2013-03-05 | 2014-09-06 | Telecom Italia Spa | Metodo per misurare e monitorare il livello di accesso a dati personali generati da risorse di un dispositivo d'utente |
| US9816387B2 (en) | 2014-09-09 | 2017-11-14 | United Technologies Corporation | Attachment faces for clamped turbine stator of a gas turbine engine |
| CA2914090C (en) | 2015-03-31 | 2023-08-01 | Allen-Vanguard Corporation | Frequency and time domain streaming receiver |
| US9714199B2 (en) | 2015-09-17 | 2017-07-25 | I P Creations Limited | Concealed amalgamated explosive neutralizer and method of manufacture |
-
2006
- 2006-08-18 DK DK06801867.0T patent/DK1971362T3/en active
- 2006-08-18 DK DK19163698.4T patent/DK3524261T5/da active
- 2006-08-18 DK DK10016112.4T patent/DK2347762T3/da active
- 2006-08-18 SG SG2012066304A patent/SG184730A1/en unknown
- 2006-08-18 AU AU2006283517A patent/AU2006283517B2/en active Active
- 2006-08-18 BR BRPI0615358A patent/BRPI0615358B8/pt active IP Right Grant
- 2006-08-18 HU HUE19163698A patent/HUE064811T2/hu unknown
- 2006-08-18 SI SI200632332T patent/SI2347762T1/sl unknown
- 2006-08-18 RS RS20150068A patent/RS53814B1/sr unknown
- 2006-08-18 PL PL10016112T patent/PL2347762T3/pl unknown
- 2006-08-18 ES ES19163698T patent/ES2968190T3/es active Active
- 2006-08-18 PT PT10016112T patent/PT2347762T/pt unknown
- 2006-08-18 PL PL19163698.4T patent/PL3524261T3/pl unknown
- 2006-08-18 PT PT68018670T patent/PT1971362E/pt unknown
- 2006-08-18 SI SI200631895T patent/SI1971362T1/sl unknown
- 2006-08-18 MX MX2008002370A patent/MX2008002370A/es active IP Right Grant
- 2006-08-18 NZ NZ593461A patent/NZ593461A/xx unknown
- 2006-08-18 KR KR1020087006560A patent/KR101059279B1/ko active Active
- 2006-08-18 NZ NZ566763A patent/NZ566763A/en unknown
- 2006-08-18 HR HRP20150186TT patent/HRP20150186T1/hr unknown
- 2006-08-18 WO PCT/US2006/032354 patent/WO2007024700A2/en not_active Ceased
- 2006-08-18 ES ES10016112T patent/ES2736184T3/es active Active
- 2006-08-18 EP EP19163698.4A patent/EP3524261B1/en active Active
- 2006-08-18 EP EP06801867.0A patent/EP1971362B1/en not_active Revoked
- 2006-08-18 RU RU2008110504/15A patent/RU2421237C2/ru active
- 2006-08-18 PT PT191636984T patent/PT3524261T/pt unknown
- 2006-08-18 EP EP10016112.4A patent/EP2347762B1/en not_active Revoked
- 2006-08-18 CA CA2619426A patent/CA2619426C/en active Active
- 2006-08-18 FI FIEP19163698.4T patent/FI3524261T3/fi active
- 2006-08-18 ES ES06801867.0T patent/ES2526463T3/es active Active
- 2006-08-18 HU HUE10016112A patent/HUE045165T2/hu unknown
- 2006-08-18 CN CN201510543460.3A patent/CN105056211A/zh active Pending
- 2006-08-18 US US12/064,216 patent/US20090239796A1/en not_active Abandoned
- 2006-08-18 JP JP2008527170A patent/JP5693817B2/ja active Active
- 2006-08-18 PL PL06801867T patent/PL1971362T3/pl unknown
- 2006-08-18 LT LTEP10016112.4T patent/LT2347762T/lt unknown
- 2006-08-18 LT LTEP19163698.4T patent/LT3524261T/lt unknown
- 2006-08-18 SI SI200632434T patent/SI3524261T1/sl unknown
-
2008
- 2008-02-19 IL IL189607A patent/IL189607A/en active IP Right Grant
-
2011
- 2011-02-16 AU AU2011200663A patent/AU2011200663B2/en active Active
- 2011-04-12 US US13/084,757 patent/US8329648B2/en active Active
-
2012
- 2012-12-07 US US13/708,474 patent/US8906851B2/en active Active
-
2014
- 2014-10-15 JP JP2014210957A patent/JP5980872B2/ja active Active
- 2014-11-25 US US14/553,549 patent/US20150150948A1/en not_active Abandoned
-
2015
- 2015-12-27 IL IL243317A patent/IL243317A0/en unknown
-
2016
- 2016-05-31 US US15/168,350 patent/US9884092B2/en active Active
-
2018
- 2018-02-05 US US15/888,519 patent/US20180333468A1/en not_active Abandoned
-
2019
- 2019-06-04 CY CY20191100588T patent/CY1122010T1/el unknown
-
2020
- 2020-01-24 US US16/752,386 patent/US20200222509A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL189607A0 (en) | Exendin for treating diabetes and reducing body weight | |
| IL189212A0 (en) | Therapeutic agent for diabetes | |
| IL192369A0 (en) | Therapeutic agent for diabetes | |
| EP1924293A4 (en) | COMPOSITION AND METHOD FOR THE PREVENTION AND TREATMENT OF DIABETES TYPE I | |
| ZA200706294B (en) | Roflumilast for the treatment of diabetes mellitus | |
| TWI366469B (en) | Emulsified skin agent for external use | |
| IL177232A0 (en) | Heteroarylaminopyrazole derivatives useful for the treatment of diabetes | |
| IL185555A0 (en) | Method and composition for treating diabetes | |
| IL189928A0 (en) | Thiophene derivatives for the treatment of diabetes | |
| EP1954800A4 (en) | COMPOSITION AND USE OF PHYTO-PERCOLATE FOR THE TREATMENT OF DISEASE | |
| EP1928247A4 (en) | COMPOSITION AND USE OF PHYTO-PERCOLATE FOR THE TREATMENT OF DISEASE | |
| EP1750698A4 (en) | 5-ANILINO-4-HETEROARYLPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | |
| EP1872126A4 (en) | CD39L3 AND ITS ROLE IN DIABETES | |
| IL200669A0 (en) | Novel preventive and/or therapeutic agent for diabetic neuropathy | |
| EP1962882A4 (en) | COMPOSITIONS AND METHOD FOR TREATING DIABETES | |
| GB0423173D0 (en) | Treatment of diabetes | |
| GB0505203D0 (en) | Skin composition treatment | |
| GB0519334D0 (en) | Method and composition for treating skin | |
| GB2433935B (en) | Compounds for treating diabetes and related disorders | |
| ZA200608015B (en) | Heteroarylaminopyrazole derivatives useful for the treatment of diabetes | |
| HU0600670D0 (en) | Complex, body weight reducing illness preventing and health restoring oxygen cure | |
| PH32005000539S1 (en) | Skin treatment articles | |
| PH32005000542S1 (en) | Skin treatment articles | |
| GB0507963D0 (en) | Composition and method for treating disease | |
| GB0522732D0 (en) | Composition and method for treating disease |