BRPI0007823A8 - Métodos de supressão do glucagon - Google Patents

Métodos de supressão do glucagon

Info

Publication number
BRPI0007823A8
BRPI0007823A8 BRPI0007823A BR0007823A BRPI0007823A8 BR PI0007823 A8 BRPI0007823 A8 BR PI0007823A8 BR PI0007823 A BRPI0007823 A BR PI0007823A BR 0007823 A BR0007823 A BR 0007823A BR PI0007823 A8 BRPI0007823 A8 BR PI0007823A8
Authority
BR
Brazil
Prior art keywords
glucagon
exendin
methods
suppression methods
glucagon suppression
Prior art date
Application number
BRPI0007823A
Other languages
English (en)
Other versions
BR0007823A (pt
Inventor
Young Andrew
Gedulin Bronislava
Original Assignee
Amylin Pharmaceuticals Inc
Amylin Pharmaceuticals Llc
Astrazeneca Pharmaceuticals Lp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27381821&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0007823(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amylin Pharmaceuticals Inc, Amylin Pharmaceuticals Llc, Astrazeneca Pharmaceuticals Lp filed Critical Amylin Pharmaceuticals Inc
Publication of BR0007823A publication Critical patent/BR0007823A/pt
Publication of BRPI0007823A8 publication Critical patent/BRPI0007823A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

MÉTODOS DE SUPRESSÃO DO GLUCAGON. São providenciados métodos para uso de uma exendina, um agonista de exendina, ou uma exendina modificada ou agonista de exendina modificada com uma exendina ou agonista de exendina ligada a um ou mais polímeros de polietilenoglicol, por exemplo, para baixar os níveis de glucagon e/ou suprimir a secreção do glucagon em um indivíduo. Esses métodos são úteis para tratamento da hiperglucagonemia e outras condições que se beneficiariam da redução do glucagon plasmático ou supressão da secreção do glucagon.
BRPI0007823A 1999-01-14 2000-01-14 Métodos de supressão do glucagon BRPI0007823A8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11638099P 1999-01-14 1999-01-14
US13201799P 1999-04-30 1999-04-30
US17536500P 2000-01-10 2000-01-10
PCT/US2000/000942 WO2000041548A2 (en) 1999-01-14 2000-01-14 Methods for glucagon suppression

Publications (2)

Publication Number Publication Date
BR0007823A BR0007823A (pt) 2001-11-20
BRPI0007823A8 true BRPI0007823A8 (pt) 2017-03-21

Family

ID=27381821

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0007823A BRPI0007823A8 (pt) 1999-01-14 2000-01-14 Métodos de supressão do glucagon

Country Status (18)

Country Link
US (3) US6872700B1 (pt)
EP (2) EP1143989B1 (pt)
JP (1) JP2002538084A (pt)
KR (2) KR20070051948A (pt)
CN (1) CN100425284C (pt)
AT (2) ATE347901T1 (pt)
AU (2) AU770712B2 (pt)
BR (1) BRPI0007823A8 (pt)
CA (1) CA2356331C (pt)
CY (1) CY1106347T1 (pt)
DE (2) DE60044041D1 (pt)
DK (1) DK1143989T3 (pt)
ES (2) ES2278589T3 (pt)
HK (1) HK1046105A1 (pt)
NO (3) NO328077B1 (pt)
NZ (1) NZ512657A (pt)
PT (1) PT1143989E (pt)
WO (1) WO2000041548A2 (pt)

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DE60032331D1 (de) 2007-01-25
EP1143989A3 (en) 2002-09-11
EP1143989B1 (en) 2006-12-13
NO20013469L (no) 2001-09-14
DE60044041D1 (de) 2010-04-29
BR0007823A (pt) 2001-11-20
HK1046105A1 (zh) 2002-12-27
CN100425284C (zh) 2008-10-15
PT1143989E (pt) 2007-03-30
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