DK1910384T3 - Imidazo [2,1-b] thiazol-derivater som sirtuinmodulerende forbindelser - Google Patents

Imidazo [2,1-b] thiazol-derivater som sirtuinmodulerende forbindelser

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Publication number
DK1910384T3
DK1910384T3 DK06789431.1T DK06789431T DK1910384T3 DK 1910384 T3 DK1910384 T3 DK 1910384T3 DK 06789431 T DK06789431 T DK 06789431T DK 1910384 T3 DK1910384 T3 DK 1910384T3
Authority
DK
Denmark
Prior art keywords
sirtuine
imidazo
modulating compounds
thiazol derivatives
thiazol
Prior art date
Application number
DK06789431.1T
Other languages
Danish (da)
English (en)
Inventor
Joseph J Nunes
Jill Milne
Jean Bemis
Roger Xie
Chi B Vu
Pui Yee Ng
Jeremy S Disch
Original Assignee
Sirtris Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sirtris Pharmaceuticals Inc filed Critical Sirtris Pharmaceuticals Inc
Application granted granted Critical
Publication of DK1910384T3 publication Critical patent/DK1910384T3/da

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Pharmacology & Pharmacy (AREA)
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  • Diabetes (AREA)
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  • Hematology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
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DK06789431.1T 2005-08-04 2006-08-04 Imidazo [2,1-b] thiazol-derivater som sirtuinmodulerende forbindelser DK1910384T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US70561205P 2005-08-04 2005-08-04
US74178305P 2005-12-02 2005-12-02
US77937006P 2006-03-03 2006-03-03
US79227606P 2006-04-14 2006-04-14
PCT/US2006/030510 WO2007019344A1 (en) 2005-08-04 2006-08-04 Imidazo [2,1-b] thiayole derivatives as sirtuin modulating compounds

Publications (1)

Publication Number Publication Date
DK1910384T3 true DK1910384T3 (da) 2012-12-17

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DK06789431.1T DK1910384T3 (da) 2005-08-04 2006-08-04 Imidazo [2,1-b] thiazol-derivater som sirtuinmodulerende forbindelser

Country Status (11)

Country Link
US (5) US20070037865A1 (OSRAM)
EP (7) EP2388263A1 (OSRAM)
JP (7) JP5203195B2 (OSRAM)
CN (1) CN103145738A (OSRAM)
AU (5) AU2006278396A1 (OSRAM)
CA (5) CA2617557A1 (OSRAM)
DK (1) DK1910384T3 (OSRAM)
ES (3) ES2397275T3 (OSRAM)
PL (1) PL1910384T3 (OSRAM)
PT (1) PT1910384E (OSRAM)
WO (5) WO2007019416A1 (OSRAM)

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US20050158376A1 (en) * 2003-10-23 2005-07-21 Sardi William F. Dietary supplement and method of processing same
US20090169585A1 (en) * 2003-10-23 2009-07-02 Resveratrol Partners, Llc Resveratrol-Containing Compositions And Their Use In Modulating Gene Product Concentration Or Activity
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
WO2006001982A2 (en) * 2004-06-04 2006-01-05 Washington University Methods and compositions for treating neuropathies
CA2593079C (en) * 2004-12-27 2014-08-19 North Shore-Long Island Jewish Research Institute Treating inflammatory disorders by electrical vagus nerve stimulation
US11207518B2 (en) * 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
EP1833819A1 (en) 2004-12-30 2007-09-19 Astex Therapeutics Limited Pyrazole compounds that modulate the activity of cdk, gsk and aurora kinases
WO2006076681A2 (en) * 2005-01-13 2006-07-20 Sirtris Pharmaceuticals, Inc. Novel compositions for preventing and treating neurodegenerative and blood coagulation disorders
CA2599989A1 (en) * 2005-03-03 2006-09-08 Sirtris Pharmaceuticals, Inc. N-phenyl benzamide derivatives as sirtuin modulators
EP1877054A2 (en) * 2005-03-30 2008-01-16 Sirtris Pharmaceuticals, Inc. Nicotinamide riboside and analogues thereof
US20070014833A1 (en) * 2005-03-30 2007-01-18 Sirtris Pharmaceuticals, Inc. Treatment of eye disorders with sirtuin modulators
US20060292099A1 (en) * 2005-05-25 2006-12-28 Michael Milburn Treatment of eye disorders with sirtuin modulators
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