DK1954697T3 - Peri-kondenserede tricykliske forbindelser, der er anvendelige som antibakterielle midler - Google Patents

Peri-kondenserede tricykliske forbindelser, der er anvendelige som antibakterielle midler

Info

Publication number
DK1954697T3
DK1954697T3 DK06849235.4T DK06849235T DK1954697T3 DK 1954697 T3 DK1954697 T3 DK 1954697T3 DK 06849235 T DK06849235 T DK 06849235T DK 1954697 T3 DK1954697 T3 DK 1954697T3
Authority
DK
Denmark
Prior art keywords
pericondensed
antibacterial agents
compounds useful
tricyclic compounds
tricyclic
Prior art date
Application number
DK06849235.4T
Other languages
English (en)
Inventor
David Thomas Davies
Nathalie Cailleau
Joel Michael Esken
Alan Joseph Hennessy
Sukumar Senthil Kumar Kusalakumari
Roger Edward Markwell
Timothy James Miles
Neil David Pearson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK1954697T3 publication Critical patent/DK1954697T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK06849235.4T 2005-10-21 2006-10-17 Peri-kondenserede tricykliske forbindelser, der er anvendelige som antibakterielle midler DK1954697T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72897505P 2005-10-21 2005-10-21
US82659006P 2006-09-22 2006-09-22
PCT/US2006/060023 WO2007081597A2 (en) 2005-10-21 2006-10-17 Peri condensed tricyclic compounds useful as antibacterial agents

Publications (1)

Publication Number Publication Date
DK1954697T3 true DK1954697T3 (da) 2010-06-14

Family

ID=38256822

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06849235.4T DK1954697T3 (da) 2005-10-21 2006-10-17 Peri-kondenserede tricykliske forbindelser, der er anvendelige som antibakterielle midler

Country Status (27)

Country Link
US (2) US20080221110A1 (da)
EP (1) EP1954697B1 (da)
JP (1) JP2009512695A (da)
KR (1) KR20080064173A (da)
AR (1) AR057981A1 (da)
AT (1) ATE458737T1 (da)
AU (1) AU2006335042A1 (da)
BR (1) BRPI0617467A2 (da)
CA (1) CA2626641A1 (da)
CR (1) CR9930A (da)
CY (1) CY1110137T1 (da)
DE (1) DE602006012535D1 (da)
DK (1) DK1954697T3 (da)
EA (1) EA200801128A1 (da)
ES (1) ES2340531T3 (da)
HK (1) HK1118546A1 (da)
HR (1) HRP20100194T8 (da)
IL (1) IL190803A0 (da)
MA (1) MA29873B1 (da)
NO (1) NO20082191L (da)
NZ (1) NZ567315A (da)
PE (1) PE20070793A1 (da)
PL (1) PL1954697T3 (da)
PT (1) PT1954697E (da)
SI (1) SI1954697T1 (da)
TW (1) TW200736263A (da)
WO (1) WO2007081597A2 (da)

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US20110275661A1 (en) * 2008-10-17 2011-11-10 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
JP4955835B2 (ja) 2008-12-12 2012-06-20 アクテリオン ファーマシューティカルズ リミテッド ５−アミノ−２−（１−ヒドロキシ−エチル）−テトラヒドロピラン誘導体
US8318940B2 (en) 2009-01-15 2012-11-27 Glaxo Group Limited Naphthyridin-2 (1 H)-one compounds useful as antibacterials
TW201313726A (zh) 2011-09-16 2013-04-01 Actelion Pharmaceuticals Ltd 製造合成之中間體之方法
JP2014533747A (ja) 2011-11-30 2014-12-15 アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ ３，７−二置換オクタヒドロ−２Ｈ−ピリド［４，３−ｅ］［１，３］オキサジン−２−オン抗生物質
MX2017002321A (es) 2014-08-22 2017-08-02 Glaxosmithkline Ip Dev Ltd Compuestos que contienen nitrogeno triciclico para tratar infeccion por neisseria gonorrhoeae.
JP6772364B2 (ja) 2017-02-28 2020-10-21 三井化学アグロ株式会社 植物病害防除組成物およびそれを施用する植物病害の防除方法
JP2020519309A (ja) * 2017-05-10 2020-07-02 アルバジュナ・セラピューティクス・エセ・エレ 高い二重のＨＩＶ抗ウイルス及び免疫調節活性を有するＦｃ融合タンパク質誘導体
CA3162166A1 (en) 2019-12-02 2021-06-10 Storm Therapeutics Limited Polyheterocyclic compounds as mettl3 inhibitors
CR20220316A (es) 2019-12-06 2022-10-07 Vertex Pharma Tetrahidrofuranos sustituidos como moduladores de canales de sodio

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Also Published As

Publication number Publication date
CR9930A (es) 2008-07-29
KR20080064173A (ko) 2008-07-08
NZ567315A (en) 2011-01-28
HRP20100194T1 (hr) 2010-05-31
SI1954697T1 (sl) 2010-05-31
WO2007081597A2 (en) 2007-07-19
HK1118546A1 (en) 2009-02-13
EA200801128A1 (ru) 2008-10-30
HRP20100194T8 (en) 2010-06-30
MA29873B1 (fr) 2008-10-03
PE20070793A1 (es) 2007-08-23
ATE458737T1 (de) 2010-03-15
EP1954697B1 (en) 2010-02-24
ES2340531T3 (es) 2010-06-04
PL1954697T3 (pl) 2010-07-30
BRPI0617467A2 (pt) 2011-07-26
TW200736263A (en) 2007-10-01
WO2007081597A3 (en) 2008-06-12
PT1954697E (pt) 2010-05-17
IL190803A0 (en) 2008-12-29
US20080221110A1 (en) 2008-09-11
US20080280892A1 (en) 2008-11-13
CA2626641A1 (en) 2007-07-19
AU2006335042A1 (en) 2007-07-19
NO20082191L (no) 2008-07-16
CY1110137T1 (el) 2015-01-14
AR057981A1 (es) 2008-01-09
JP2009512695A (ja) 2009-03-26
DE602006012535D1 (de) 2010-04-08
EP1954697A2 (en) 2008-08-13

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