HRP20100194T8 - Peri condensed tricyclic compounds useful as antibacterial agents - Google Patents
Peri condensed tricyclic compounds useful as antibacterial agentsInfo
- Publication number
- HRP20100194T8 HRP20100194T8 HR20100194T HRP20100194T HRP20100194T8 HR P20100194 T8 HRP20100194 T8 HR P20100194T8 HR 20100194 T HR20100194 T HR 20100194T HR P20100194 T HRP20100194 T HR P20100194T HR P20100194 T8 HRP20100194 T8 HR P20100194T8
- Authority
- HR
- Croatia
- Prior art keywords
- alkyl
- cr4r8
- aromatic ring
- hydroxy
- hydrogen
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 8
- 125000006574 non-aromatic ring group Chemical group 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 125000003118 aryl group Chemical group 0.000 abstract 5
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 101000585507 Solanum tuberosum Cytochrome b-c1 complex subunit 7 Proteins 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 101150020251 NR13 gene Proteins 0.000 abstract 3
- 125000004414 alkyl thio group Chemical group 0.000 abstract 3
- 125000003277 amino group Chemical group 0.000 abstract 3
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 3
- 229910052760 oxygen Inorganic materials 0.000 abstract 3
- 229910052717 sulfur Inorganic materials 0.000 abstract 3
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 3
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000005647 linker group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 abstract 1
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
- 125000002527 bicyclic carbocyclic group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72897505P | 2005-10-21 | 2005-10-21 | |
| US82659006P | 2006-09-22 | 2006-09-22 | |
| PCT/US2006/060023 WO2007081597A2 (en) | 2005-10-21 | 2006-10-17 | Peri condensed tricyclic compounds useful as antibacterial agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20100194T1 HRP20100194T1 (hr) | 2010-05-31 |
| HRP20100194T8 true HRP20100194T8 (en) | 2010-06-30 |
Family
ID=38256822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100194T HRP20100194T8 (en) | 2005-10-21 | 2010-04-07 | Peri condensed tricyclic compounds useful as antibacterial agents |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US20080280892A1 (xx) |
| EP (1) | EP1954697B1 (xx) |
| JP (1) | JP2009512695A (xx) |
| KR (1) | KR20080064173A (xx) |
| AR (1) | AR057981A1 (xx) |
| AT (1) | ATE458737T1 (xx) |
| AU (1) | AU2006335042A1 (xx) |
| BR (1) | BRPI0617467A2 (xx) |
| CA (1) | CA2626641A1 (xx) |
| CR (1) | CR9930A (xx) |
| CY (1) | CY1110137T1 (xx) |
| DE (1) | DE602006012535D1 (xx) |
| DK (1) | DK1954697T3 (xx) |
| EA (1) | EA200801128A1 (xx) |
| ES (1) | ES2340531T3 (xx) |
| HK (1) | HK1118546A1 (xx) |
| HR (1) | HRP20100194T8 (xx) |
| IL (1) | IL190803A0 (xx) |
| MA (1) | MA29873B1 (xx) |
| NO (1) | NO20082191L (xx) |
| NZ (1) | NZ567315A (xx) |
| PE (1) | PE20070793A1 (xx) |
| PL (1) | PL1954697T3 (xx) |
| PT (1) | PT1954697E (xx) |
| SI (1) | SI1954697T1 (xx) |
| TW (1) | TW200736263A (xx) |
| WO (1) | WO2007081597A2 (xx) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602006012535D1 (de) * | 2005-10-21 | 2010-04-08 | Glaxo Group Ltd | Peri-kondensierte tricyclische verbindungen verwendbar als antibakterielle mittel |
| ATE465163T1 (de) | 2005-12-22 | 2010-05-15 | Glaxo Group Ltd | Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel |
| US7709483B2 (en) | 2006-04-06 | 2010-05-04 | Glaxo Group Limited | Pyrrolo-quinoxalinone derivatives as antibacterials |
| GB0608263D0 (en) | 2006-04-26 | 2006-06-07 | Glaxo Group Ltd | Compounds |
| GB0613208D0 (en) * | 2006-07-03 | 2006-08-09 | Glaxo Group Ltd | Compounds |
| GB0705672D0 (en) * | 2007-03-23 | 2007-05-02 | Glaxo Group Ltd | Compounds |
| CL2008001002A1 (es) | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| KR101567096B1 (ko) * | 2007-04-20 | 2015-11-06 | 글락소 그룹 리미티드 | 항균제로서의 트리시클릭 질소 함유 화합물 |
| GB0707706D0 (en) * | 2007-04-20 | 2007-05-30 | Glaxo Group Ltd | Compounds |
| EP2005995A1 (en) * | 2007-06-22 | 2008-12-24 | Glaxo Group Limited | Heterocyclic compounds for the treatment of tuberculosis |
| EP2080761A1 (en) | 2008-01-18 | 2009-07-22 | Glaxo Group Limited | Compounds |
| WO2009104147A2 (en) | 2008-02-20 | 2009-08-27 | Actelion Pharmaceuticals Ltd | Azatricyclic antibiotic compounds |
| EP2276766A1 (en) | 2008-04-15 | 2011-01-26 | Actelion Pharmaceuticals Ltd. | Tricyclic antibiotics |
| JP2011529960A (ja) | 2008-08-04 | 2011-12-15 | アクテリオン ファーマシューティカルズ リミテッド | 三環式アルキルアミノメチルオキサゾリジノン誘導体 |
| PT2344495E (pt) * | 2008-10-07 | 2015-04-01 | Actelion Pharmaceuticals Ltd | Compostos antibióticos de oxazolidinona tricíclica |
| WO2010043714A1 (en) | 2008-10-17 | 2010-04-22 | Glaxo Group Limited | Tricyclic nitrogen compounds used as antibacterials |
| SI2376497T1 (sl) | 2008-12-12 | 2014-01-31 | Actelion Pharmaceuticals Ltd. | Derivati 5-amino-2-(1-hidroksi-etil)-tetrahidropirana |
| ES2561631T3 (es) | 2009-01-15 | 2016-02-29 | Glaxo Group Limited | Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos |
| WO2013038374A1 (en) | 2011-09-16 | 2013-03-21 | Actelion Pharmaceuticals Ltd | Process for manufacturing a synthetic intermediate |
| TW201326180A (zh) | 2011-11-30 | 2013-07-01 | Actelion Pharmaceuticals Ltd | ３，７－二取代八氫－２Ｈ－吡啶并［４，３－ｅ］［１，３］□嗪－２－酮抗生素 |
| EA031589B1 (ru) | 2014-08-22 | 2019-01-31 | Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | Трициклические азотсодержащие соединения для лечения инфекции, вызываемой neisseria gonorrhoeae |
| EP3590341A4 (en) | 2017-02-28 | 2021-03-10 | Mitsui Chemicals Agro, Inc. | PLANT DISEASE PREVENTION COMPOSITION AND METHOD FOR PREVENTING PLANT DISEASES USING IT |
| CN111405910A (zh) * | 2017-05-10 | 2020-07-10 | 阿尔巴朱纳治疗有限公司 | 具有高HIV抗病毒和免疫调节双重活性的Fc融合蛋白衍生物 |
| CN115151540A (zh) | 2019-12-02 | 2022-10-04 | 风暴治疗有限公司 | 作为mettl3抑制剂的多杂环化合物 |
| CR20220316A (es) | 2019-12-06 | 2022-10-07 | Vertex Pharma | Tetrahidrofuranos sustituidos como moduladores de canales de sodio |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3323868A (en) * | 1961-12-14 | 1967-06-06 | Laporte Chemical | Manufacture of hydrogen peroxide |
| BE634031A (xx) * | 1962-06-23 | |||
| GB1394373A (en) * | 1972-05-17 | 1975-05-14 | Pfizer Ltd | Control of plant diseases |
| US4066706A (en) * | 1975-04-21 | 1978-01-03 | Halcon International, Inc. | Preparation of ethylbenzene hydroperoxide |
| DE2805915C3 (de) * | 1978-02-13 | 1981-11-05 | Dynamit Nobel Ag, 5210 Troisdorf | Reaktor zur Oxidation von Gemischen aus p-Xylol und p-Toluylsäuremethylester mit sauerstoffhaltigen Gasen in flüssiger Phase |
| US4416884A (en) * | 1978-04-12 | 1983-11-22 | Otsuka Pharmaceutical Co., Ltd. | Piperazinylbenzoheterocyclic compounds |
| DE2914218C2 (de) * | 1978-04-12 | 1985-10-24 | Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo | N-Acylderivate des Ampicillins und Amoxicillins, Verfahren zu deren Herstellung und pharmazeutische Zubereitungen, welche die Verbindungen enthalten |
| NO156828C (no) * | 1980-11-10 | 1987-12-02 | Otsuka Pharma Co Ltd | Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser. |
| ATE21514T1 (de) * | 1982-03-25 | 1986-09-15 | Ciba Geigy Ag | Verfahren zur herstellung von 1,2,5,6-tetrahydro4h-pyrrolo(3,2,1-ij)-chinolin-4-on und neue 5ch820325 |
| US4595755A (en) * | 1982-03-25 | 1986-06-17 | Ciba-Geigy Corporation | 5-halo-1,2,3-(1,2-dihydropyrrolo)-4-quinolones |
| US4603199A (en) * | 1982-10-25 | 1986-07-29 | Riker Laboratories, Inc. | Phenyl-substituted tricyclic antibacterial agent intermediates |
| US4443447A (en) * | 1982-10-25 | 1984-04-17 | Riker Laboratories, Inc. | Phenyl-substituted tricyclic antibacterial agents |
| US6121285A (en) * | 1995-11-22 | 2000-09-19 | Daiichi Pharmaceutical Co., Ltd. | Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives |
| GB9622386D0 (en) * | 1996-10-28 | 1997-01-08 | Sandoz Ltd | Organic compounds |
| JPH11222407A (ja) * | 1997-11-14 | 1999-08-17 | Sankyo Co Ltd | 新規殺菌剤 |
| US6289745B1 (en) * | 1999-05-04 | 2001-09-18 | James Bowers | High temperature insertion type flow element and mounting extension |
| US7825121B2 (en) * | 1999-05-04 | 2010-11-02 | Schering Corporation | Piperazine derivatives useful as CCR5 antagonists |
| US6689765B2 (en) * | 1999-05-04 | 2004-02-10 | Schering Corporation | Piperazine derivatives useful as CCR5 antagonists |
| US6391865B1 (en) * | 1999-05-04 | 2002-05-21 | Schering Corporation | Piperazine derivatives useful as CCR5 antagonists |
| GB0101577D0 (en) * | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| UY27192A1 (es) * | 2001-03-01 | 2002-09-30 | Smithkline Beecham Corp | Inhibidores de peptido-deformilasa |
| GB0112836D0 (en) * | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| WO2003064431A2 (en) * | 2002-01-29 | 2003-08-07 | Glaxo Group Limited | Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them |
| AR040336A1 (es) * | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto |
| PA8577501A1 (es) * | 2002-07-25 | 2004-02-07 | Warner Lambert Co | Inhibidores de quinasas |
| AR042486A1 (es) | 2002-12-18 | 2005-06-22 | Glaxo Group Ltd | Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion . |
| DK1675852T3 (da) * | 2003-09-22 | 2009-05-25 | Janssen Pharmaceutica Nv | Heterocykliske 7-amino-alkylidenyl-quinoloner og -naphthyridoner |
| US7691850B2 (en) * | 2004-06-15 | 2010-04-06 | Glaxo Group Limited | Antibacterial agents |
| JP2008505920A (ja) * | 2004-07-08 | 2008-02-28 | グラクソ グループ リミテッド | 抗菌剤 |
| US7732612B2 (en) * | 2004-09-09 | 2010-06-08 | Janssen Pharmaceutica, N.V. | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| MY150958A (en) * | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| WO2006137485A1 (ja) * | 2005-06-24 | 2006-12-28 | Toyama Chemical Co., Ltd. | 新規な含窒素複素環化合物およびその塩 |
| DE602006012535D1 (de) * | 2005-10-21 | 2010-04-08 | Glaxo Group Ltd | Peri-kondensierte tricyclische verbindungen verwendbar als antibakterielle mittel |
| DE102005050892A1 (de) * | 2005-10-21 | 2007-04-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| GB0521563D0 (en) * | 2005-10-21 | 2005-11-30 | Glaxo Group Ltd | Novel compounds |
| ATE465163T1 (de) * | 2005-12-22 | 2010-05-15 | Glaxo Group Ltd | Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel |
| US7709483B2 (en) * | 2006-04-06 | 2010-05-04 | Glaxo Group Limited | Pyrrolo-quinoxalinone derivatives as antibacterials |
| GB0608263D0 (en) * | 2006-04-26 | 2006-06-07 | Glaxo Group Ltd | Compounds |
| KR101409261B1 (ko) * | 2006-05-26 | 2014-06-18 | 다이쇼 세이야꾸 가부시끼가이샤 | 신규의 복소환 화합물 또는 그 염 및 그 중간체 |
| GB0613208D0 (en) * | 2006-07-03 | 2006-08-09 | Glaxo Group Ltd | Compounds |
| EP1992628A1 (en) * | 2007-05-18 | 2008-11-19 | Glaxo Group Limited | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones |
| GB0705672D0 (en) * | 2007-03-23 | 2007-05-02 | Glaxo Group Ltd | Compounds |
| EP1980251A1 (en) * | 2007-04-13 | 2008-10-15 | Glaxo Group Limited | Pyrrolo[3,2,1-ij]quinoline-4-one derivatives for treating tuberculosis |
| GB0707706D0 (en) * | 2007-04-20 | 2007-05-30 | Glaxo Group Ltd | Compounds |
| GB0707708D0 (en) * | 2007-04-20 | 2007-05-30 | Glaxo Group Ltd | Compounds |
| KR101567096B1 (ko) * | 2007-04-20 | 2015-11-06 | 글락소 그룹 리미티드 | 항균제로서의 트리시클릭 질소 함유 화합물 |
-
2006
- 2006-10-17 DE DE602006012535T patent/DE602006012535D1/de active Active
- 2006-10-17 WO PCT/US2006/060023 patent/WO2007081597A2/en active Application Filing
- 2006-10-17 SI SI200630624T patent/SI1954697T1/sl unknown
- 2006-10-17 PT PT06849235T patent/PT1954697E/pt unknown
- 2006-10-17 CA CA002626641A patent/CA2626641A1/en not_active Abandoned
- 2006-10-17 US US12/090,947 patent/US20080280892A1/en not_active Abandoned
- 2006-10-17 ES ES06849235T patent/ES2340531T3/es active Active
- 2006-10-17 JP JP2008536625A patent/JP2009512695A/ja active Pending
- 2006-10-17 EP EP06849235A patent/EP1954697B1/en active Active
- 2006-10-17 DK DK06849235.4T patent/DK1954697T3/da active
- 2006-10-17 AT AT06849235T patent/ATE458737T1/de active
- 2006-10-17 KR KR1020087012082A patent/KR20080064173A/ko not_active Application Discontinuation
- 2006-10-17 BR BRPI0617467-1A patent/BRPI0617467A2/pt not_active IP Right Cessation
- 2006-10-17 NZ NZ567315A patent/NZ567315A/en unknown
- 2006-10-17 AU AU2006335042A patent/AU2006335042A1/en not_active Abandoned
- 2006-10-17 PL PL06849235T patent/PL1954697T3/pl unknown
- 2006-10-17 EA EA200801128A patent/EA200801128A1/xx unknown
- 2006-10-17 US US11/550,005 patent/US20080221110A1/en not_active Abandoned
- 2006-10-19 PE PE2006001266A patent/PE20070793A1/es not_active Application Discontinuation
- 2006-10-19 TW TW095138495A patent/TW200736263A/zh unknown
- 2006-10-19 AR ARP060104571A patent/AR057981A1/es not_active Application Discontinuation
-
2008
- 2008-04-10 IL IL190803A patent/IL190803A0/en unknown
- 2008-04-15 MA MA30851A patent/MA29873B1/fr unknown
- 2008-04-25 CR CR9930A patent/CR9930A/es not_active Application Discontinuation
- 2008-05-13 NO NO20082191A patent/NO20082191L/no not_active Application Discontinuation
- 2008-09-10 HK HK08110046.5A patent/HK1118546A1/xx not_active IP Right Cessation
-
2010
- 2010-04-07 HR HR20100194T patent/HRP20100194T8/xx unknown
- 2010-05-10 CY CY20101100405T patent/CY1110137T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ567315A (en) | 2011-01-28 |
| DK1954697T3 (da) | 2010-06-14 |
| EA200801128A1 (ru) | 2008-10-30 |
| BRPI0617467A2 (pt) | 2011-07-26 |
| SI1954697T1 (sl) | 2010-05-31 |
| MA29873B1 (fr) | 2008-10-03 |
| WO2007081597A2 (en) | 2007-07-19 |
| IL190803A0 (en) | 2008-12-29 |
| ES2340531T3 (es) | 2010-06-04 |
| HK1118546A1 (en) | 2009-02-13 |
| CR9930A (es) | 2008-07-29 |
| AR057981A1 (es) | 2008-01-09 |
| US20080280892A1 (en) | 2008-11-13 |
| KR20080064173A (ko) | 2008-07-08 |
| US20080221110A1 (en) | 2008-09-11 |
| PE20070793A1 (es) | 2007-08-23 |
| CA2626641A1 (en) | 2007-07-19 |
| AU2006335042A1 (en) | 2007-07-19 |
| CY1110137T1 (el) | 2015-01-14 |
| NO20082191L (no) | 2008-07-16 |
| WO2007081597A3 (en) | 2008-06-12 |
| EP1954697A2 (en) | 2008-08-13 |
| TW200736263A (en) | 2007-10-01 |
| HRP20100194T1 (hr) | 2010-05-31 |
| PT1954697E (pt) | 2010-05-17 |
| JP2009512695A (ja) | 2009-03-26 |
| PL1954697T3 (pl) | 2010-07-30 |
| EP1954697B1 (en) | 2010-02-24 |
| ATE458737T1 (de) | 2010-03-15 |
| DE602006012535D1 (de) | 2010-04-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20100194T8 (en) | Peri condensed tricyclic compounds useful as antibacterial agents | |
| AR066111A1 (es) | Compuesto triciclico de imidazol, su uso para preparar un medicamento, composicion farmaceutica que lo comprende y compuestos intermediarios en la sintesis de dicho compuesto | |
| AR058587A1 (es) | Compuestos de pirrolo-1,5-naftiridinona,su uso como agentes antibacterianos, composiciones farmaceuticas que los contienen y compuestos intermediarios para preparar dichos compuestos | |
| ECSP066967A (es) | Derivados de tetrahidroquinolina y un procedimiento para preparar los mismos | |
| AR061918A1 (es) | Compuesto biciclico que contiene nitrogeno, su uso para la fabricacion de un medicamento y composicion farmaceutica que lo comprende | |
| AR060287A1 (es) | Compuesto de 5,6 dihidro-3h-pirrolo[1,2,3-de]quinoxalini-3-ona, su uso para preparar un medicamento, composicion farmaceutica que lo comprende y compuesto intermediario util para su preparacion | |
| PE20090276A1 (es) | Compuestos derivados de imidazoquinolina como moduladores de tlr7 | |
| PE20091573A1 (es) | Derivados heterociclicos de urea como inhibidores de adn girasa y/o topoisomerasa | |
| AR047902A1 (es) | Compuestos como inhibidores de ns3 serina proteasa del virus de hepatitis c | |
| PE20060770A1 (es) | Derivados de n-[(4,5-difenil-3-alquil-2-tienil)metil]amina como antagonistas de los receptores cannabinoides cb1 | |
| AR071385A1 (es) | Compuestos de 2-imino-3-metil pirrolopirimidinona sustituida con tiofenilo,composiciones farmaceuticas que los contienen,y uso de los mismos para el tratamiento de patologias asociadas con la proteina beta amiloide,tales como alzheimer y otros formas de demencia. | |
| NO20052976D0 (no) | Fosfodiesterase-4-inhibitorer. | |
| AR043938A1 (es) | Compuesto heterociclico derivado de quinolina o naftiridina, composicion farmaceutica que lo comprende y su uso para preparar esta ultima | |
| AR047537A1 (es) | Piridazinonaureas como antagonistas de integrinas | |
| AR057380A1 (es) | Compuestos quimicos derivados de 2-azetidinona y uso terapeutico de los mismos | |
| AR049696A1 (es) | Derivados de indol | |
| AR047538A1 (es) | Piridazinonas como antagonistas de las integrinas alfa4 | |
| BRPI0413233A (pt) | novos compostos | |
| PE20061106A1 (es) | Derivados de 2-(4-oxo-4h-quinazolin-3-il)acetamida | |
| PE20070321A1 (es) | Compuestos heterociclicos como inhibidores de proteasas | |
| AR055592A1 (es) | Derivados de 2-amino-5-cicloalquil-hidantoina como moduladores y/o inhibidores de la beta-secretasa(bace) | |
| PE20060599A1 (es) | DERIVADOS PIRAZOLO-[3,4-d]-PIRIMIDINA COMO INHIBIDORES DE LA ACTIVIDAD DEL RECEPTOR CANNABINOIDE 1 | |
| HRP20090264T1 (en) | Phenyl-piperazin methanone derivatives | |
| DOP2010000226A (es) | Compuestos triciclicos que tienen actividad antagonista de factor de liberacion de corticotropina y composiciones farmaceuticas que contienen los mismos | |
| ATE271868T1 (de) | Neue cathechole als antimikrobielle mittel |