DK0526452T4 - Hybridimmunoglobuliner - Google Patents

Hybridimmunoglobuliner

Info

Publication number
DK0526452T4
DK0526452T4 DK91901202T DK91901202T DK0526452T4 DK 0526452 T4 DK0526452 T4 DK 0526452T4 DK 91901202 T DK91901202 T DK 91901202T DK 91901202 T DK91901202 T DK 91901202T DK 0526452 T4 DK0526452 T4 DK 0526452T4
Authority
DK
Denmark
Prior art keywords
hybrid immunoglobulin
useful
methods
peptides
ligands
Prior art date
Application number
DK91901202T
Other languages
Danish (da)
English (en)
Other versions
DK0526452T3 (da
Inventor
Daniel J Capon
Laurence A Lasky
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23749509&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0526452(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DK0526452T3 publication Critical patent/DK0526452T3/da
Application granted granted Critical
Publication of DK0526452T4 publication Critical patent/DK0526452T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
DK91901202T 1989-11-22 1990-11-21 Hybridimmunoglobuliner DK0526452T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/440,625 US5116964A (en) 1989-02-23 1989-11-22 Hybrid immunoglobulins
PCT/US1990/006849 WO1991008298A2 (en) 1989-11-22 1990-11-21 Fusion proteins consisting of a ligand binding protein and a stable plasma protein

Publications (2)

Publication Number Publication Date
DK0526452T3 DK0526452T3 (da) 2001-06-18
DK0526452T4 true DK0526452T4 (da) 2007-05-07

Family

ID=23749509

Family Applications (2)

Application Number Title Priority Date Filing Date
DK91901202T DK0526452T4 (da) 1989-11-22 1990-11-21 Hybridimmunoglobuliner
DK99123412T DK1029870T3 (da) 1989-11-22 1990-11-21 Hybride immunglobuliner til anvendelse i terapeutiske fremgangsmåder

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK99123412T DK1029870T3 (da) 1989-11-22 1990-11-21 Hybride immunglobuliner til anvendelse i terapeutiske fremgangsmåder

Country Status (13)

Country Link
US (1) US5116964A (es)
EP (3) EP1970386A2 (es)
JP (2) JPH05503009A (es)
AT (2) ATE396735T1 (es)
CA (1) CA2072642C (es)
DE (3) DE69034253D1 (es)
DK (2) DK0526452T4 (es)
ES (2) ES2308826T3 (es)
GR (1) GR3035856T3 (es)
HK (2) HK1030222A1 (es)
LU (1) LU91498I2 (es)
NL (1) NL300372I1 (es)
WO (1) WO1991008298A2 (es)

Families Citing this family (616)

* Cited by examiner, † Cited by third party
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EP1970386A2 (en) 2008-09-17
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WO1991008298A2 (en) 1991-06-13
EP1029870A3 (en) 2000-12-13
GR3035856T3 (en) 2001-08-31
EP1029870A2 (en) 2000-08-23
DK1029870T3 (da) 2008-09-29
DE69034253D1 (de) 2008-07-10
EP1029870B1 (en) 2008-05-28
HK1013298A1 (en) 1999-08-20
HK1030222A1 (en) 2001-04-27
DK0526452T3 (da) 2001-06-18
CA2072642C (en) 2002-07-23
ES2155819T3 (es) 2001-06-01
EP0526452A1 (en) 1993-02-10
EP0526452B1 (en) 2001-02-21
ATE199261T1 (de) 2001-03-15
CA2072642A1 (en) 1991-05-23
NL300372I1 (nl) 2009-02-02
US5116964A (en) 1992-05-26
WO1991008298A3 (en) 1991-10-17
JP2002325589A (ja) 2002-11-12
DE69033705T3 (de) 2007-07-12
DE69033705D1 (de) 2001-03-29
ES2308826T3 (es) 2008-12-01
DE69033705T2 (de) 2001-08-02
ES2155819T5 (es) 2007-09-16
DE122008000063I1 (de) 2009-02-19
EP1970386A8 (en) 2009-07-08
LU91498I2 (fr) 2009-01-19
DE122008000063I2 (de) 2011-06-16
ATE396735T1 (de) 2008-06-15

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