ATE523593T1 - Membranproteine aus säugetierzellen und verwandte reagentien - Google Patents

Membranproteine aus säugetierzellen und verwandte reagentien

Info

Publication number
ATE523593T1
ATE523593T1 AT06019631T AT06019631T ATE523593T1 AT E523593 T1 ATE523593 T1 AT E523593T1 AT 06019631 T AT06019631 T AT 06019631T AT 06019631 T AT06019631 T AT 06019631T AT E523593 T1 ATE523593 T1 AT E523593T1
Authority
AT
Austria
Prior art keywords
cell membrane
membrane proteins
mammal cell
related reagents
proteins
Prior art date
Application number
AT06019631T
Other languages
English (en)
Inventor
Alexander B H Bakker
Joseph H Phillips Jr
Lewis L Lanier
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE523593T1 publication Critical patent/ATE523593T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06019631T 1997-08-01 1998-07-31 Membranproteine aus säugetierzellen und verwandte reagentien ATE523593T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90490597A 1997-08-01 1997-08-01
US6371797P 1997-10-29 1997-10-29
US99082097A 1997-12-15 1997-12-15
US6969297P 1997-12-16 1997-12-16
US8916898P 1998-06-12 1998-06-12

Publications (1)

Publication Number Publication Date
ATE523593T1 true ATE523593T1 (de) 2011-09-15

Family

ID=27535631

Family Applications (2)

Application Number Title Priority Date Filing Date
AT06019631T ATE523593T1 (de) 1997-08-01 1998-07-31 Membranproteine aus säugetierzellen und verwandte reagentien
AT98937993T ATE341626T1 (de) 1997-08-01 1998-07-31 Membranproteine aus säugetierzellen; verwandte reagentien

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT98937993T ATE341626T1 (de) 1997-08-01 1998-07-31 Membranproteine aus säugetierzellen; verwandte reagentien

Country Status (8)

Country Link
EP (3) EP1798286B1 (de)
JP (3) JP2001512017A (de)
AT (2) ATE523593T1 (de)
AU (1) AU8661498A (de)
DE (1) DE69836082T2 (de)
ES (1) ES2274574T3 (de)
PT (1) PT1003861E (de)
WO (1) WO1999006557A2 (de)

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WO2002068628A1 (en) * 2001-02-23 2002-09-06 Human Genome Sciences, Inc. 70 human secreted proteins
US7196164B2 (en) 1997-07-08 2007-03-27 Human Genome Sciences, Inc. Secreted protein HHTLF25
EP1557425A3 (de) * 1997-07-08 2005-08-17 Human Genome Sciences, Inc. Humanes sekeretiertes Protein
EP1373890A2 (de) * 2000-09-20 2004-01-02 Institut National De La Sante Et De La Recherche Medicale (Inserm) Mittel zur identifizierung von verbindungen die eine inhibierung von karap-übermittelten signalen ermöglichen
JP2004522742A (ja) 2000-12-08 2004-07-29 ベイラー　カレッジ　オブ　メディシン 免疫応答の改変において使用するためのｔｒｅｍ−１スプライス改変体
CA2585719A1 (en) 2004-11-08 2006-05-18 Schering Corporation Tumor association of mdl-1 and methods
EP1991577A2 (de) * 2006-01-31 2008-11-19 Parkinson, John F. Modulation der mdl-1-aktivität zur behandlung entzündlicher krankheiten
EP2152750A1 (de) 2007-04-23 2010-02-17 Schering Corporation Anti-mdl-1-antikörper
EP2675467A4 (de) * 2011-02-18 2014-06-25 Merck Sharp & Dohme Verwendung von mdl-1-antagonisten zur behandlung von spondylarthropathie
WO2013043516A1 (en) 2011-09-23 2013-03-28 Merck Sharp & Dohme Corp. Mdl-1 ligand
EA031948B1 (ru) 2011-11-16 2019-03-29 Бёрингер Ингельхайм Интернациональ Гмбх Антитело к il-36r или его антигенсвязывающий фрагмент, выделенный полинуклеотид, клетка-хозяин и способ получения этого антитела или его фрагмента, содержащая их фармацевтическая композиция и применение антитела или его фрагмента и композиции
AR090915A1 (es) 2012-05-04 2014-12-17 Intervet Int Bv Proteina de fusion de proteina linfopoyetina estromal timica canina con la region fc de igg
US9511092B2 (en) 2013-01-28 2016-12-06 St. Jude Children's Research Hospital, Inc. Chimeric receptor with NKG2D specificity for use in cell therapy against cancer and infectious disease
WO2014126902A1 (en) * 2013-02-15 2014-08-21 Thomas Jefferson University Kit for tumor imaging
CN112175911B (zh) 2014-05-15 2023-10-13 新加坡国立大学 经修饰的自然杀伤细胞及其用途
WO2016044605A1 (en) 2014-09-17 2016-03-24 Beatty, Gregory Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
SG11201908492PA (en) 2017-03-27 2019-10-30 Nat Univ Singapore Truncated nkg2d chimeric receptors and uses thereof in natural killer cell immunotherapy
SG11202007156QA (en) 2018-02-09 2020-08-28 Nat Univ Singapore Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
AU2019236105B2 (en) 2018-03-14 2025-07-31 Boehringer Ingelheim International Gmbh Use of anti-IL-36R antibodies for treatment of generalized pustular psoriasis
WO2019193476A1 (en) 2018-04-02 2019-10-10 National University Of Singapore Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
CN108728527B (zh) * 2018-06-06 2020-06-09 青岛泱深生物医药有限公司 Hcst基因作为诊治子痫前期的靶标
EP3844186A4 (de) 2018-08-29 2022-08-17 National University of Singapore Verfahren zur spezifischen stimulation des überlebens und der expansion von genetisch modifizierten immunzellen
CN113766956B (zh) 2019-03-05 2024-05-07 恩卡尔塔公司 Cd19定向性嵌合抗原受体及其在免疫疗法中的用途
EA202192405A1 (ru) 2019-03-08 2022-01-13 Бёрингер Ингельхайм Интернациональ Гмбх Составы антител против il-36r
WO2022015920A1 (en) 2020-07-17 2022-01-20 Boehringer Ingelheim International Gmbh Anti-il-36r antibodies for the treatment of neutrophilic dermatoses

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DE2031216A1 (de) 1969-06-19 1971-01-14 Citizen Watch Co Ltd , Tokio Tag und Datum Stellvorrichtung fur Uhren mit Kalender
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
WO1996026961A2 (en) * 1995-02-28 1996-09-06 National Jewish Center For Immunology And Respiratory Medicine Peptidyl compounds comprising an itim motif which regulate hematopoietic function and their use
WO1997020046A1 (en) * 1995-11-30 1997-06-05 Schering Corporation Dnam, an nk antigen and adhesion molecule of the immunoglobulin superfamily
WO1998039446A2 (en) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 70 human secreted proteins
EP0977855A2 (de) * 1997-04-30 2000-02-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Polypeptide assoziiert mit aktivatorrezeptoren und deren biologische anwendungen
JP2002513295A (ja) * 1997-07-08 2002-05-08 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド １２３種類のヒト分泌タンパク質
JP2001512016A (ja) * 1997-08-01 2001-08-21 ジェンセット 筋肉およびその他中胚葉組織中で発現される分泌タンパク質の５’ｅｓｔ
PT1000146E (pt) * 1997-08-01 2006-10-31 Serono Genetics Inst Sa Ests 5' para proteinas secretadas sem especificidade tecidular

Also Published As

Publication number Publication date
WO1999006557A2 (en) 1999-02-11
EP1798286A3 (de) 2007-11-14
ES2274574T3 (es) 2007-05-16
JP2010099076A (ja) 2010-05-06
AU8661498A (en) 1999-02-22
JP2010099077A (ja) 2010-05-06
JP2001512017A (ja) 2001-08-21
EP1798286A2 (de) 2007-06-20
EP1798287A3 (de) 2007-11-14
ATE341626T1 (de) 2006-10-15
EP1798287A2 (de) 2007-06-20
DE69836082D1 (de) 2006-11-16
WO1999006557A3 (en) 1999-05-20
EP1003861B1 (de) 2006-10-04
JP4855513B2 (ja) 2012-01-18
EP1003861A2 (de) 2000-05-31
DE69836082T2 (de) 2007-05-10
PT1003861E (pt) 2007-01-31
EP1798286B1 (de) 2011-09-07

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