WO1999047673A3 - Isolated mammalian membrane protein genes and related reagents - Google Patents

Isolated mammalian membrane protein genes and related reagents Download PDF

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Publication number
WO1999047673A3
WO1999047673A3 PCT/US1999/003740 US9903740W WO9947673A3 WO 1999047673 A3 WO1999047673 A3 WO 1999047673A3 US 9903740 W US9903740 W US 9903740W WO 9947673 A3 WO9947673 A3 WO 9947673A3
Authority
WO
WIPO (PCT)
Prior art keywords
membrane protein
protein genes
isolated mammalian
related reagents
mammalian membrane
Prior art date
Application number
PCT/US1999/003740
Other languages
French (fr)
Other versions
WO1999047673A2 (en
Inventor
Lionel Chalus
Ahn B Quan
Elizabeth Esther Mary Bates
Daniel M Gorman
Sem Saeland
Serge J E Lebecque
Joseph H Philipps Jr
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Priority to EP99912218A priority Critical patent/EP1064371A2/en
Priority to AU30636/99A priority patent/AU3063699A/en
Priority to CA002323083A priority patent/CA2323083A1/en
Priority to JP2000536856A priority patent/JP2002506645A/en
Publication of WO1999047673A2 publication Critical patent/WO1999047673A2/en
Publication of WO1999047673A3 publication Critical patent/WO1999047673A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056Lectin superfamily, e.g. CD23, CD72
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

Nucleic acids encoding various dendritic cell membrane proteins, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
PCT/US1999/003740 1998-03-17 1999-03-16 Isolated mammalian membrane protein genes and related reagents WO1999047673A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99912218A EP1064371A2 (en) 1998-03-17 1999-03-16 Isolated mammalian membrane protein genes and related reagents
AU30636/99A AU3063699A (en) 1998-03-17 1999-03-16 Isolated mammalian membrane protein genes and related reagents
CA002323083A CA2323083A1 (en) 1998-03-17 1999-03-16 Isolated mammalian membrane protein genes and related reagents
JP2000536856A JP2002506645A (en) 1998-03-17 1999-03-16 Isolated mammalian membrane protein genes and related reagents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4011198A 1998-03-17 1998-03-17
US09/040,111 1998-03-17

Publications (2)

Publication Number Publication Date
WO1999047673A2 WO1999047673A2 (en) 1999-09-23
WO1999047673A3 true WO1999047673A3 (en) 1999-11-18

Family

ID=21909167

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/003740 WO1999047673A2 (en) 1998-03-17 1999-03-16 Isolated mammalian membrane protein genes and related reagents

Country Status (5)

Country Link
EP (1) EP1064371A2 (en)
JP (1) JP2002506645A (en)
AU (1) AU3063699A (en)
CA (1) CA2323083A1 (en)
WO (1) WO1999047673A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030162955A1 (en) * 1998-03-17 2003-08-28 Lionel Chalus Isolated mammalian membrane protein genes; related reagents
CN1454215B (en) * 1999-11-15 2013-01-02 米勒腾尼生物技术有限公司 Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
DK1282646T3 (en) 2000-05-08 2012-05-14 Celldex Res Corp HUMAN MONOCLONAL ANTIBODIES AGAINST DENDRITIC CELLS
US7560534B2 (en) 2000-05-08 2009-07-14 Celldex Research Corporation Molecular conjugates comprising human monoclonal antibodies to dendritic cells
EP1881065A1 (en) * 2001-03-27 2008-01-23 Novartis AG DINO polypetide
US9259459B2 (en) 2003-01-31 2016-02-16 Celldex Therapeutics Inc. Antibody vaccine conjugates and uses therefor
WO2004074432A2 (en) 2003-01-31 2004-09-02 Celldex Therapeutics, Inc. Antibody vaccine conjugates and uses therefor
KR101624751B1 (en) 2007-11-07 2016-05-27 셀덱스 쎄라퓨틱스, 인크. Antibodies that bind human dendritic and epithelial cell 205(dec-205)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998002456A2 (en) * 1996-07-15 1998-01-22 Incyte Pharma Inc Human c-type lectin
WO1998028332A2 (en) * 1996-12-20 1998-07-02 Board Of Regents, The University Of Texas System Unique dendritic cell-associated c-type lectins, dectin-1 and dectin-2; compositions and uses thereof
JPH111497A (en) * 1997-06-13 1999-01-06 Takeda Chem Ind Ltd New membrane protein and its dna
WO1999002562A1 (en) * 1997-07-09 1999-01-21 Schering Corporation Isolated dendritic cell membrane protein genes

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998002456A2 (en) * 1996-07-15 1998-01-22 Incyte Pharma Inc Human c-type lectin
WO1998028332A2 (en) * 1996-12-20 1998-07-02 Board Of Regents, The University Of Texas System Unique dendritic cell-associated c-type lectins, dectin-1 and dectin-2; compositions and uses thereof
JPH111497A (en) * 1997-06-13 1999-01-06 Takeda Chem Ind Ltd New membrane protein and its dna
WO1999002562A1 (en) * 1997-07-09 1999-01-21 Schering Corporation Isolated dendritic cell membrane protein genes

Non-Patent Citations (14)

* Cited by examiner, † Cited by third party
Title
ANNUAL MEETING OF THE SOCIETY FOR INVESTIGATIVE DERMATOLOGY WASHINGTON, D.C., USA APRIL 23-27, 1997 *
ARIIZUMI, K. (1) ET AL: "Isolation of a dendritic cell-specific transcription unit, dectin -2 promoter.", JOURNAL OF DERMATOLOGICAL SCIENCE, (MARCH, 1998) VOL. 16, NO. SUPPL. 1, PP. S3. MEETING INFO.: THIRD JOINT MEETING OF THE EUROPEAN SOCIETY FOR DERMATOLOGICAL RESEARCH, JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY, COLOGNE MAY 7-10 1998, XP002116893 *
ARIIZUMI, K. ET AL: "Identification and characterization of genomic DNA for dectin -2.", JOURNAL OF INVESTIGATIVE DERMATOLOGY, (1997) VOL. 109, NO. 2, PP. 254. MEETING, XP002116890 *
ARIIZUMI, KIYOSHI ET AL: "Identification of dectin -2, a second member of a new dendritic cell-associated C-type lectin family.", JOURNAL OF INVESTIGATIVE DERMATOLOGY, (1997) VOL. 108, NO. 4, PP. 564. MEETING, XP002116889 *
DATABASE MPSRCH GENBANK 1 January 1900 (1900-01-01), XP002116017, Database accession no. X01259 *
DATABASE MPSRCH GENBANK 1 January 1900 (1900-01-01), XP002116018, Database accession no. W73889 *
DATABASE MPSRCH GENBANK 1 January 1900 (1900-01-01), XP002116019, Database accession no. X01260 *
DATABASE MPSRCH GENBANK 1 January 1900 (1900-01-01), XP002116020, Database accession no. W73888 *
DATABASE WPI Section Ch Week 9911, Derwent World Patents Index; Class B04, AN 99-125479, XP002116016 *
FIFTH INTERNATIONAL WORKSHOP ON LANGERHANS CELLS SALZBURG, AUSTRIA SEPTEMBER 5-7, 1997 *
THIRD JOINT MEETING OF THE EUROPEAN SOCIETY FOR DERMATOLOGICAL RESEARCH, JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY, SOCIETY FOR INVESTIGATIBE DERMATOLOGY, COLOGNE MAY 7-10 1998 *
THIRD JOINT MEETING OF THE EUROPEAN SOCIETY FOR DERMATOLOGICAL RESEARCH, JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY, SOCIETY FOR INVESTIGATIVE DERMATOLOGY, COLOGNE MAY 7-10 1998 *
YOKOTA, K. ET AL: "Identification of human equivalents of murine dectin -1 and dectin -2.", JOURNAL OF INVESTIGATIVE DERMATOLOGY, (1997) VOL. 109, NO. 2, PP. 267., August 1997 (1997-08-01), XP002116891 *
YOKOTA, K. ET AL: "Molecular cloning of a new human C-type lectin with significant homology to mouse dectin -2.", JOURNAL OF DERMATOLOGICAL SCIENCE, (MARCH, 1998) VOL. 16, NO. SUPPL. 1, PP. S89., XP002116892 *

Also Published As

Publication number Publication date
EP1064371A2 (en) 2001-01-03
CA2323083A1 (en) 1999-09-23
JP2002506645A (en) 2002-03-05
AU3063699A (en) 1999-10-11
WO1999047673A2 (en) 1999-09-23

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