BRPI0510691A - marcadores de haplótipos e métodos de uso dos mesmos para determinar resposta ao tratamento - Google Patents

marcadores de haplótipos e métodos de uso dos mesmos para determinar resposta ao tratamento

Info

Publication number
BRPI0510691A
BRPI0510691A BRPI0510691-5A BRPI0510691A BRPI0510691A BR PI0510691 A BRPI0510691 A BR PI0510691A BR PI0510691 A BRPI0510691 A BR PI0510691A BR PI0510691 A BRPI0510691 A BR PI0510691A
Authority
BR
Brazil
Prior art keywords
methods
treatment
present
haplotype
determine response
Prior art date
Application number
BRPI0510691-5A
Other languages
English (en)
Inventor
Beena Koshy
Bradley J Dain
Madan Kamur Anant
Ping Zhan
Original Assignee
Genaissance Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals filed Critical Genaissance Pharmaceuticals
Publication of BRPI0510691A publication Critical patent/BRPI0510691A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70528—CD58
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

MARCADORES DE HAPLóTIPOS E MéTODOS DE USO DOS MESMOS PARA DETERMINAR RESPOSTA AO TRATAMENTO. A presente invenção relaciona-se a métodos para diagnóstico ou previsão da capacidade de resposta ao tratamento, como Alefacept, por determinação da presença de um nucleotídeo em um ou mais sítios polimórficos em um marcador de haplótipo. A presente invenção identifica múltiplos haplótipos que estão associados à resposta a Alefacept. Os marcadores de haplótipo identificados pela presente invenção e métodos da invenção podem ser particularmente úteis para o diagnóstico ou previsão da suscetibilidade a doenças da pele, como Psoríase.
BRPI0510691-5A 2004-05-04 2005-05-04 marcadores de haplótipos e métodos de uso dos mesmos para determinar resposta ao tratamento BRPI0510691A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56837104P 2004-05-04 2004-05-04
PCT/US2005/015531 WO2005112568A2 (en) 2004-05-04 2005-05-04 Haplotype markers and methods of using the same to determine response to treatment

Publications (1)

Publication Number Publication Date
BRPI0510691A true BRPI0510691A (pt) 2007-12-26

Family

ID=35428732

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510691-5A BRPI0510691A (pt) 2004-05-04 2005-05-04 marcadores de haplótipos e métodos de uso dos mesmos para determinar resposta ao tratamento

Country Status (9)

Country Link
US (1) US20080020383A1 (pt)
EP (1) EP1747291A2 (pt)
KR (1) KR20070011558A (pt)
CN (1) CN1997756A (pt)
BR (1) BRPI0510691A (pt)
CA (1) CA2565804A1 (pt)
IL (1) IL178970A0 (pt)
MX (1) MXPA06012744A (pt)
WO (1) WO2005112568A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2149612A1 (en) * 2008-07-29 2010-02-03 Merck Serono SA Genetic markers of response to efalizumab
GB2467161A (en) 2009-01-26 2010-07-28 Sharp Kk Nitride nanoparticles
GB2467162A (en) 2009-01-26 2010-07-28 Sharp Kk Fabrication of nitride nanoparticles
KR101823699B1 (ko) * 2009-09-28 2018-01-30 인타르시아 세라퓨틱스 인코포레이티드 실질 항정상태 약물 전달의 신속 확립 및/또는 종결
KR20170023776A (ko) 2014-02-26 2017-03-06 루마 세러퓨틱스 인코포레이티드 자외선 광선 치료 장치들 및 방법들
CN109310527A (zh) 2016-02-09 2019-02-05 鲁玛治疗公司 用于通过光疗法来治疗牛皮癣的方法、组合物和设备
CN114085873A (zh) * 2021-11-16 2022-02-25 珠海中科先进技术研究院有限公司 一种癌细胞状态辨识基因电路组及其制备方法

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Also Published As

Publication number Publication date
MXPA06012744A (es) 2007-02-19
WO2005112568A3 (en) 2006-05-11
EP1747291A2 (en) 2007-01-31
WO2005112568A2 (en) 2005-12-01
CA2565804A1 (en) 2005-12-01
KR20070011558A (ko) 2007-01-24
US20080020383A1 (en) 2008-01-24
CN1997756A (zh) 2007-07-11
IL178970A0 (en) 2007-03-08

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2099 DE 29/03/2011.