BE2012C036I2 - - Google Patents
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- Publication number
- BE2012C036I2 BE2012C036I2 BE2012C036C BE2012C036C BE2012C036I2 BE 2012C036 I2 BE2012C036 I2 BE 2012C036I2 BE 2012C036 C BE2012C036 C BE 2012C036C BE 2012C036 C BE2012C036 C BE 2012C036C BE 2012C036 I2 BE2012C036 I2 BE 2012C036I2
- Authority
- BE
- Belgium
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99402759 | 1999-11-05 | ||
EP99402877 | 1999-11-19 | ||
PCT/GB2000/004181 WO2001032651A1 (fr) | 1999-11-05 | 2000-11-01 | Derives de quinazoline utilises en tant qu'inhibiteurs du facteur de croissance endotheliale vasculaire (vegf) |
Publications (1)
Publication Number | Publication Date |
---|---|
BE2012C036I2 true BE2012C036I2 (fr) | 2019-12-11 |
Family
ID=26153696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE2012C036C BE2012C036I2 (fr) | 1999-11-05 | 2012-08-09 |
Country Status (36)
Country | Link |
---|---|
US (9) | US7173038B1 (fr) |
EP (2) | EP1244647B1 (fr) |
JP (1) | JP3522727B2 (fr) |
KR (3) | KR100881104B1 (fr) |
CN (2) | CN101219145A (fr) |
AR (1) | AR033499A1 (fr) |
AT (2) | ATE398120T1 (fr) |
AU (1) | AU769222B2 (fr) |
BE (1) | BE2012C036I2 (fr) |
BG (1) | BG65861B1 (fr) |
BR (2) | BR0015203A (fr) |
CA (1) | CA2389767C (fr) |
CY (3) | CY1106166T1 (fr) |
CZ (1) | CZ301689B6 (fr) |
DE (2) | DE60039206D1 (fr) |
DK (2) | DK1676845T3 (fr) |
EE (1) | EE05330B1 (fr) |
ES (2) | ES2265998T3 (fr) |
FR (1) | FR12C0048I2 (fr) |
HK (2) | HK1049664B (fr) |
HU (1) | HU229414B1 (fr) |
IL (2) | IL149034A0 (fr) |
IS (2) | IS2284B (fr) |
LU (1) | LU92057I2 (fr) |
MX (1) | MXPA02004366A (fr) |
NO (2) | NO322298B1 (fr) |
NZ (1) | NZ518028A (fr) |
PL (1) | PL203782B1 (fr) |
PT (2) | PT1244647E (fr) |
RU (1) | RU2291868C2 (fr) |
SI (2) | SI1244647T1 (fr) |
SK (1) | SK287401B6 (fr) |
TW (1) | TWI287540B (fr) |
UA (1) | UA72946C2 (fr) |
WO (1) | WO2001032651A1 (fr) |
ZA (1) | ZA200202775B (fr) |
Families Citing this family (216)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9718972D0 (en) * | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
BR0015203A (pt) | 1999-11-05 | 2002-07-16 | Astrazeneca Ab | Derivado de quinazolina, processo para a preparação de um derivado de quinazolina, composição farmacêutica, uso de um composto, e, processo para a produção de um efeito antiangiogênico e/ou redutor de permeabilidade vascular em um animal de sangue quente |
GB0008269D0 (en) * | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Combination chemotherapy |
GB0126879D0 (en) * | 2001-11-08 | 2002-01-02 | Astrazeneca Ab | Combination therapy |
US20050163781A1 (en) * | 2002-01-29 | 2005-07-28 | Philippe Koninckx | Tissue adhesion formation control |
PL371486A1 (en) * | 2002-02-01 | 2005-06-13 | Astrazeneca Ab | Quinazoline compounds |
US6924285B2 (en) | 2002-03-30 | 2005-08-02 | Boehringer Ingelheim Pharma Gmbh & Co. | Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them |
JP4703183B2 (ja) | 2002-07-15 | 2011-06-15 | シンフォニー エボルーション, インク. | 受容体型キナーゼモジュレーターおよびその使用方法 |
AU2003249000B2 (en) * | 2002-08-09 | 2007-04-05 | Astrazeneca Ab | Combination of ZD6474, an inhibitor of the vasuclar endothelial growth factor receptor, with radiotherapy in the treatment of cancer |
DE10237423A1 (de) | 2002-08-16 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von LCK-Inhibitoren für die Behandlung von immunologischen Erkrankungen |
GB0223380D0 (en) * | 2002-10-09 | 2002-11-13 | Astrazeneca Ab | Combination therapy |
EP1562955B1 (fr) * | 2002-11-04 | 2008-02-27 | Astrazeneca AB | Derives de quinazoline utilises comme inhibiteurs de src tyrosine kinase |
KR20110006699A (ko) * | 2003-02-13 | 2011-01-20 | 아스트라제네카 아베 | 5-플루오로우라실 또는/및 이리노테칸과 4-(4-브로모-2-플루오로아닐리노)-6-메톡시-7-(1-메틸피페리딘-4-일메톡시)퀴나졸린의 병용 요법 |
US20050043233A1 (en) | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
GB0316176D0 (en) * | 2003-07-10 | 2003-08-13 | Astrazeneca Ab | Combination therapy |
KR20060033782A (ko) * | 2003-07-10 | 2006-04-19 | 아스트라제네카 아베 | 백금 화합물 및 임의적으로 이온화 방사능과 조합된퀴나졸린 유도체 zd6474의 혈관신생 및/또는 증가된 혈관투과성 관련 질환 치료 용도 |
MXPA06000508A (es) | 2003-07-18 | 2006-04-05 | Amgen Inc | Agentes de union especifica al factor del crecimiento de los hepatocitos. |
GB0317665D0 (en) | 2003-07-29 | 2003-09-03 | Astrazeneca Ab | Qinazoline derivatives |
GB0318423D0 (en) * | 2003-08-06 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
UA84167C2 (ru) * | 2003-09-16 | 2008-09-25 | Астразенека Аб | Производные хиназолина как ингибиторы тирозинкиназы, способ их получения (варианты), фармацевтическая композиция на их основе |
JP2007506716A (ja) * | 2003-09-25 | 2007-03-22 | アストラゼネカ アクチボラグ | キナゾリン誘導体 |
GB0330002D0 (en) * | 2003-12-24 | 2004-01-28 | Astrazeneca Ab | Quinazoline derivatives |
EP1713781B1 (fr) | 2004-02-03 | 2008-11-05 | AstraZeneca AB | Derives de quinazoline |
GB0421438D0 (en) * | 2004-09-27 | 2004-10-27 | Astrazeneca Ab | Combination therapy |
GB0411378D0 (en) | 2004-05-21 | 2004-06-23 | Astrazeneca Ab | Pharmaceutical compositions |
EP1765313A2 (fr) * | 2004-06-24 | 2007-03-28 | Novartis Vaccines and Diagnostics, Inc. | Composes utilises pour l'immunopotentialisation |
KR20070072543A (ko) * | 2004-09-27 | 2007-07-04 | 아스트라제네카 아베 | Zd6474 및 이마티닙을 포함하는 병합법 |
GB0424339D0 (en) * | 2004-11-03 | 2004-12-08 | Astrazeneca Ab | Combination therapy |
EP1827434B1 (fr) | 2004-11-30 | 2014-01-15 | Amgen Inc. | Heterocycles substitues et leurs procedes d'utilisation |
AU2005319382B2 (en) | 2004-12-21 | 2011-04-07 | Astrazeneca Ab | Antibodies directed to angiopoietin-2 and uses thereof |
CN1854130B (zh) * | 2005-04-15 | 2011-04-20 | 中国医学科学院药物研究所 | 喹唑啉衍生物、及其制法和药物组合物与用途 |
DK1922307T3 (da) | 2005-05-18 | 2012-04-02 | Array Biopharma Inc | Heterocykliske inhibitorer af MEK og fremgangsmåder til anvendelse heraf |
AU2011203358B2 (en) * | 2005-09-30 | 2013-05-30 | Genzyme Corporation | Chemical process |
GB0519878D0 (en) * | 2005-09-30 | 2005-11-09 | Astrazeneca Ab | Chemical compound |
GB0519879D0 (en) * | 2005-09-30 | 2005-11-09 | Astrazeneca Ab | Chemical process |
US20080108664A1 (en) | 2005-12-23 | 2008-05-08 | Liu Belle B | Solid-state form of AMG 706 and pharmaceutical compositions thereof |
JO2660B1 (en) | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
AR059066A1 (es) * | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
WO2007092178A1 (fr) | 2006-02-10 | 2007-08-16 | Amgen Inc. | Formes hydrate d'amg706 |
AR060358A1 (es) | 2006-04-06 | 2008-06-11 | Novartis Vaccines & Diagnostic | Quinazolinas para la inhibicion de pdk 1 |
TW200813091A (en) | 2006-04-10 | 2008-03-16 | Amgen Fremont Inc | Targeted binding agents directed to uPAR and uses thereof |
WO2007124288A1 (fr) | 2006-04-19 | 2007-11-01 | Novartis Ag | Indazoles et méthodes d'inhibition de cdc7 |
PE20121506A1 (es) | 2006-07-14 | 2012-11-26 | Amgen Inc | Compuestos triazolopiridinas como inhibidores de c-met |
US8217177B2 (en) | 2006-07-14 | 2012-07-10 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
CL2007002225A1 (es) | 2006-08-03 | 2008-04-18 | Astrazeneca Ab | Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un |
AR062207A1 (es) | 2006-08-04 | 2008-10-22 | Takeda Pharmaceutical | Derivados de imidazopiridazina inhibidores de quinasas utiles para prevenir y/o tratar el cancer. |
RU2445312C2 (ru) | 2006-08-23 | 2012-03-20 | Кудос Фармасьютиклз Лимитед | ПРОИЗВОДНЫЕ 2-МЕТИЛМОРФОЛИН ПИРИДО-, ПИРАЗО- И ПИРИМИДО-ПИРИМИДИНА В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR |
US20100092466A1 (en) | 2006-09-29 | 2010-04-15 | Anderson Joseph Ryan | Combination of zd6474 and bevacizumab for cancer therapy |
US8916552B2 (en) | 2006-10-12 | 2014-12-23 | Astex Therapeutics Limited | Pharmaceutical combinations |
JP5528807B2 (ja) | 2006-10-12 | 2014-06-25 | アステックス、セラピューティックス、リミテッド | 複合薬剤 |
WO2008046242A1 (fr) * | 2006-10-16 | 2008-04-24 | Institute Of Mataria Medica, Chinese Academy Of Medical Sciences | Nouveaux dérivés quinazolines, leurs procédés de préparation et leurs utilisations |
EP1921070A1 (fr) | 2006-11-10 | 2008-05-14 | Boehringer Ingelheim Pharma GmbH & Co. KG | heterocycles bicycliques, medicaments á base de ces composes, leur usage et procédé pour leur preparation |
CA2672438A1 (fr) | 2006-12-20 | 2008-07-03 | Amgen Inc. | Heterocycles substitues et leurs methodes d'utilisation |
US7759344B2 (en) | 2007-01-09 | 2010-07-20 | Amgen Inc. | Bis-aryl amide derivatives and methods of use |
AU2008212999A1 (en) | 2007-02-06 | 2008-08-14 | Boehringer Ingelheim International Gmbh | Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof |
US20080190689A1 (en) * | 2007-02-12 | 2008-08-14 | Ballard Ebbin C | Inserts for engine exhaust systems |
JP2010519204A (ja) | 2007-02-16 | 2010-06-03 | アムジエン・インコーポレーテツド | 窒素含有複素環ケトン類およびそれらのc−Met阻害薬としての使用 |
US8044056B2 (en) | 2007-03-20 | 2011-10-25 | Dainippon Sumitomo Pharma Co., Ltd. | Adenine compound |
PE20081887A1 (es) | 2007-03-20 | 2009-01-16 | Dainippon Sumitomo Pharma Co | Nuevo compuesto de adenina |
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JP5352476B2 (ja) | 2007-06-05 | 2013-11-27 | 武田薬品工業株式会社 | キナーゼ阻害剤としての二環式複素環化合物 |
BRPI0815368A2 (pt) | 2007-08-21 | 2015-02-10 | Amgen Inc | "proteinas c-fms humanas a antigeno" |
US8324395B2 (en) | 2007-08-23 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
CA2701057C (fr) | 2007-10-11 | 2015-03-24 | Astrazeneca Ab | Derives pyrrolo[2,3-d]pyrimidine comme inhibiteurs de la proteine kinase b |
MX2010006800A (es) | 2007-12-19 | 2010-10-05 | Genentech Inc | 5-anilinoimidazopiridinas y metodos de uso de las mismas. |
JP2011506560A (ja) | 2007-12-20 | 2011-03-03 | ノバルティス アーゲー | Pi3キナーゼ阻害剤として用いられるチアゾール誘導体 |
NZ586575A (en) | 2007-12-21 | 2012-03-30 | Genentech Inc | Azaindolizines and methods of use |
US8609673B2 (en) * | 2008-01-22 | 2013-12-17 | Concert Pharmaceuticals, Inc. | Vandetanib derivatives |
KR20100111291A (ko) | 2008-02-07 | 2010-10-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 스피로사이클릭 헤테로사이클, 상기 화합물을 함유하는 약제, 이의 용도 및 이의 제조 방법 |
MX2010009156A (es) * | 2008-02-21 | 2010-09-09 | Astrazeneca Ab | Terapia de combinacion 238. |
WO2009138781A1 (fr) | 2008-05-13 | 2009-11-19 | Astrazeneca Ab | Sel de fumarate de 4-(3-chloro-2-fluoroanilino)-7-méthoxy-6-{[1-(n-méthylcarbamoylméthyl)pipéridin-4-yl]oxy}quinazoline |
AU2009269149B2 (en) | 2008-06-30 | 2016-03-17 | Mesoblast, Inc. | Treatment of eye diseases and excessive neovascularization using a combined therapy |
EP2313397B1 (fr) | 2008-08-08 | 2016-04-20 | Boehringer Ingelheim International GmbH | Hétérocycles substitués par cyclohexyloxy, médicament contenant ces liaisons, leur utilisation et leur procédé de fabrication |
KR20110057244A (ko) | 2008-09-19 | 2011-05-31 | 메디뮨 엘엘씨 | Dll4에 대한 항체 및 이의 용도 |
JP5579619B2 (ja) | 2008-12-01 | 2014-08-27 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
JO3101B1 (ar) | 2008-12-02 | 2017-09-20 | Takeda Pharmaceuticals Co | مشتقات بنزوثيازول كعوامل مضادة للسرطان |
UY32351A (es) | 2008-12-22 | 2010-07-30 | Astrazeneca Ab | Compuestos de pirimidinil indol para uso como inhibidores de atr |
EP2379595A2 (fr) | 2008-12-23 | 2011-10-26 | AstraZeneca AB | Agents de liaison ciblés dirigés contre 5 1 et leurs applications |
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ES2529205T3 (es) | 2009-03-13 | 2015-02-17 | Cellzome Limited | Derivados de pirimidina como inhibidores de mTOR |
WO2010108503A1 (fr) | 2009-03-24 | 2010-09-30 | Life & Brain Gmbh | Promotion de l'intégration neuronale dans des greffons de cellules souches neurales |
WO2010118986A1 (fr) | 2009-04-14 | 2010-10-21 | Cellzome Limited | Composés de pyrimidine substitués par fluoro en tant qu'inhibiteurs de jak3 |
US8293753B2 (en) | 2009-07-02 | 2012-10-23 | Novartis Ag | Substituted 2-carboxamide cycloamino ureas |
WO2011029807A1 (fr) | 2009-09-11 | 2011-03-17 | Cellzome Limited | Composés de pyrimidine ortho-substitués en tant qu'inhibiteurs de jak |
WO2011048082A1 (fr) | 2009-10-20 | 2011-04-28 | Cellzome Limited | Analogues d'hétérocyclyl pyrazolopyrimidine en tant qu'inhibiteurs de jak |
CN102070608A (zh) * | 2009-11-19 | 2011-05-25 | 天津药物研究院 | 4-取代苯胺基-7-取代烷氧基-喹唑啉衍生物、其制备方法和用途 |
SI3279215T1 (sl) | 2009-11-24 | 2020-07-31 | Medimmune Limited | Usmerjena vezavna sredstva proti B7-H1 |
WO2011068233A1 (fr) | 2009-12-03 | 2011-06-09 | Dainippon Sumitomo Pharma Co., Ltd. | Imidazoquinolines agissant par l'intermédiaire des récepteurs de type toll (tlr) |
AU2011215900A1 (en) | 2010-02-10 | 2012-07-26 | Immunogen, Inc. | CD20 antibodies and uses thereof |
EP2542536B1 (fr) | 2010-03-04 | 2015-01-21 | Cellzome Limited | Dérivés d'urée à substitution morpholino en tant qu'inhibiteurs mTOR |
MX2012012328A (es) | 2010-04-30 | 2013-05-06 | Cellzome Ltd | Compuestos pirazol como inhibidores de jak. |
SA111320519B1 (ar) | 2010-06-11 | 2014-07-02 | Astrazeneca Ab | مركبات بيريميدينيل للاستخدام كمثبطات atr |
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