CN103483276B - 一种凡德他尼杂质的制备方法 - Google Patents
一种凡德他尼杂质的制备方法 Download PDFInfo
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- CN103483276B CN103483276B CN201310428221.4A CN201310428221A CN103483276B CN 103483276 B CN103483276 B CN 103483276B CN 201310428221 A CN201310428221 A CN 201310428221A CN 103483276 B CN103483276 B CN 103483276B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
Abstract
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Claims (6)
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CN201310428221.4A CN103483276B (zh) | 2013-09-22 | 2013-09-22 | 一种凡德他尼杂质的制备方法 |
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CN201310428221.4A CN103483276B (zh) | 2013-09-22 | 2013-09-22 | 一种凡德他尼杂质的制备方法 |
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CN103483276A CN103483276A (zh) | 2014-01-01 |
CN103483276B true CN103483276B (zh) | 2018-04-17 |
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CN201310428221.4A Active CN103483276B (zh) | 2013-09-22 | 2013-09-22 | 一种凡德他尼杂质的制备方法 |
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Families Citing this family (1)
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US10011587B2 (en) | 2014-05-15 | 2018-07-03 | The Methodist Hospital System | Multivalent ligands targeting VEGFR |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0566226A1 (en) * | 1992-01-20 | 1993-10-20 | Zeneca Limited | Quinazoline derivatives |
CN101219145A (zh) * | 1999-11-05 | 2008-07-16 | 阿斯特拉曾尼卡有限公司 | 作为vegf抑制剂的喹唑啉衍生物 |
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2013
- 2013-09-22 CN CN201310428221.4A patent/CN103483276B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0566226A1 (en) * | 1992-01-20 | 1993-10-20 | Zeneca Limited | Quinazoline derivatives |
CN101219145A (zh) * | 1999-11-05 | 2008-07-16 | 阿斯特拉曾尼卡有限公司 | 作为vegf抑制剂的喹唑啉衍生物 |
Non-Patent Citations (2)
Title |
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Isolation and structure elucidation of the main UV-A photoproducts of vandetanib;Stefano Dall’Acqua,等;《Journal of Pharmaceutical and Biomedical Analysis》;20130618;第84卷;196-200 * |
凡德他尼;赵兴旺;《中国药物化学杂志》;20111031;第21卷(第5期);405 * |
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CN103483276A (zh) | 2014-01-01 |
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Address after: Qixia District of Nanjing City, Jiangsu province 210033 Xianlin streets latitude road No. 9, building F6, room 317 Applicant after: Nanjing H&D Pharmaceutical Technology Co.,Ltd. Address before: 210038 No. 422, Yan Lu, Nanjing, Jiangsu Applicant before: Nanjing H&D Pharmaceutical Technology Co.,Ltd. |
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Address after: 210033 room 317, building F6, No.9, Weidi Road, Xianlin street, Qixia District, Nanjing City, Jiangsu Province Patentee after: Nanjing H&D Pharmaceutical Technology Co.,Ltd. Address before: 210033 room 317, building F6, No.9, Weidi Road, Xianlin street, Qixia District, Nanjing City, Jiangsu Province Patentee before: Nanjing H&D Pharmaceutical Technology Co.,Ltd. |
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CP02 | Change in the address of a patent holder |
Address after: Building D3, No. 9, Weidi Road, Xianlin Street, Qixia District, Nanjing, Jiangsu 210033 Patentee after: Nanjing H&D Pharmaceutical Technology Co.,Ltd. Address before: 210033 room 317, building F6, No.9, Weidi Road, Xianlin street, Qixia District, Nanjing City, Jiangsu Province Patentee before: Nanjing H&D Pharmaceutical Technology Co.,Ltd. |