AU2007345526B2 - Compounds for the prevention and treatment of cardiovascular diseases - Google Patents

Compounds for the prevention and treatment of cardiovascular diseases Download PDF

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Publication number
AU2007345526B2
AU2007345526B2 AU2007345526A AU2007345526A AU2007345526B2 AU 2007345526 B2 AU2007345526 B2 AU 2007345526B2 AU 2007345526 A AU2007345526 A AU 2007345526A AU 2007345526 A AU2007345526 A AU 2007345526A AU 2007345526 B2 AU2007345526 B2 AU 2007345526B2
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dimethoxy
ethyl
oxo
alkoxy
dimethylphenoxy
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AU2007345526A
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AU2007345526A1 (en
AU2007345526A2 (en
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Henrik Hansen
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Resverlogix Corp
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Resverlogix Corp
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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    • A61L31/16—Biologically active materials, e.g. therapeutic substances
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2007345526A 2007-02-01 2007-02-01 Compounds for the prevention and treatment of cardiovascular diseases Active AU2007345526B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/CA2007/000146 WO2008092231A1 (en) 2007-02-01 2007-02-01 Compounds for the prevention and treatment of cardiovascular diseases
US11/670,238 US8053440B2 (en) 2007-02-01 2007-02-01 Compounds for the prevention and treatment of cardiovascular diseases

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AU2007345526A1 AU2007345526A1 (en) 2008-08-07
AU2007345526A2 AU2007345526A2 (en) 2009-10-08
AU2007345526B2 true AU2007345526B2 (en) 2013-02-28

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EP (1) EP2118074B1 (cg-RX-API-DMAC7.html)
JP (1) JP5236664B2 (cg-RX-API-DMAC7.html)
KR (1) KR101444489B1 (cg-RX-API-DMAC7.html)
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DK2118074T3 (en) * 2007-02-01 2014-03-10 Resverlogix Corp Compounds for the prevention and treatment of cardiovascular diseases
US20080255161A1 (en) * 2007-04-11 2008-10-16 Dmitry Koltun 3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
WO2009134616A2 (en) * 2008-04-15 2009-11-05 Intermune, Inc. Novel inhibitors of hepatitis c virus replication
EP2346837B8 (en) * 2008-06-26 2015-04-15 Resverlogix Corporation Methods of preparing quinazolinone derivatives
CN101628913B (zh) * 2008-07-18 2013-01-23 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
CA2731926A1 (en) 2008-08-05 2010-02-11 Boehringer Ingelheim International Gmbh 4-dimethylamino-phenyl-substituted naphthyridines, and use thereof as medicaments
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