ATE445400T1 - Hydantion-derivate als hemmer von matrix- metalloproteinasen - Google Patents

Hydantion-derivate als hemmer von matrix- metalloproteinasen

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Publication number
ATE445400T1
ATE445400T1 AT02741724T AT02741724T ATE445400T1 AT E445400 T1 ATE445400 T1 AT E445400T1 AT 02741724 T AT02741724 T AT 02741724T AT 02741724 T AT02741724 T AT 02741724T AT E445400 T1 ATE445400 T1 AT E445400T1
Authority
AT
Austria
Prior art keywords
inhibitors
matrix metalloproteinases
derivatives
hydantion
aggrecanase
Prior art date
Application number
AT02741724T
Other languages
English (en)
Inventor
James Sheppeck
Jingwu Duan
Chu-Biao Xue
Zelda Wasserman
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23129620&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE445400(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE445400T1 publication Critical patent/ATE445400T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C—CHEMISTRY; METALLURGY
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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AT02741724T 2001-05-25 2002-05-23 Hydantion-derivate als hemmer von matrix- metalloproteinasen ATE445400T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29357101P 2001-05-25 2001-05-25
PCT/US2002/016381 WO2002096426A1 (en) 2001-05-25 2002-05-23 Hydantion derivatives as inhibitors of matrix metalloproteinases

Publications (1)

Publication Number Publication Date
ATE445400T1 true ATE445400T1 (de) 2009-10-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
AT02741724T ATE445400T1 (de) 2001-05-25 2002-05-23 Hydantion-derivate als hemmer von matrix- metalloproteinasen

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US (3) US6890915B2 (de)
EP (1) EP1397137B1 (de)
JP (1) JP2004535411A (de)
AT (1) ATE445400T1 (de)
CA (1) CA2447475A1 (de)
DE (1) DE60234028D1 (de)
ES (1) ES2333412T3 (de)
WO (1) WO2002096426A1 (de)

Families Citing this family (88)

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Publication number Priority date Publication date Assignee Title
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