SE0403085D0 - Novel componds - Google Patents

Novel componds

Info

Publication number
SE0403085D0
SE0403085D0 SE0403085A SE0403085A SE0403085D0 SE 0403085 D0 SE0403085 D0 SE 0403085D0 SE 0403085 A SE0403085 A SE 0403085A SE 0403085 A SE0403085 A SE 0403085A SE 0403085 D0 SE0403085 D0 SE 0403085D0
Authority
SE
Sweden
Prior art keywords
componds
novel
pharmaceutical compositions
compounds
therapy
Prior art date
Application number
SE0403085A
Other languages
English (en)
Inventor
Magnus Munck Af Rosenschoeld
Michael Lundkvist
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0403085A priority Critical patent/SE0403085D0/sv
Publication of SE0403085D0 publication Critical patent/SE0403085D0/sv
Priority to UAA200706657A priority patent/UA90285C2/ru
Priority to KR1020077013489A priority patent/KR20070090924A/ko
Priority to JP2007546609A priority patent/JP2008524210A/ja
Priority to CA002590845A priority patent/CA2590845A1/en
Priority to RU2007126746/04A priority patent/RU2376301C2/ru
Priority to AT05815745T priority patent/ATE545642T1/de
Priority to MX2007007023A priority patent/MX2007007023A/es
Priority to NZ555831A priority patent/NZ555831A/en
Priority to AU2005317286A priority patent/AU2005317286B2/en
Priority to US11/721,586 priority patent/US7655664B2/en
Priority to ES05815745T priority patent/ES2380670T3/es
Priority to EP05815745A priority patent/EP1831199B1/en
Priority to BRPI0517035-4A priority patent/BRPI0517035A/pt
Priority to CNA2005800481778A priority patent/CN101119987A/zh
Priority to PCT/SE2005/001917 priority patent/WO2006065215A1/en
Priority to ARP050105273A priority patent/AR051795A1/es
Priority to MYPI20055915A priority patent/MY147770A/en
Priority to TW094144602A priority patent/TW200635917A/zh
Priority to SA05260409A priority patent/SA05260409B1/ar
Priority to IL183599A priority patent/IL183599A/en
Priority to ZA200705075A priority patent/ZA200705075B/xx
Priority to NO20073572A priority patent/NO20073572L/no
Priority to US12/697,625 priority patent/US20100256166A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
SE0403085A 2004-12-17 2004-12-17 Novel componds SE0403085D0 (sv)

Priority Applications (24)

Application Number Priority Date Filing Date Title
SE0403085A SE0403085D0 (sv) 2004-12-17 2004-12-17 Novel componds
PCT/SE2005/001917 WO2006065215A1 (en) 2004-12-17 2005-12-14 Novel compounds
US11/721,586 US7655664B2 (en) 2004-12-17 2005-12-14 Hydantoin derivatives as metalloproteinase inhibitors
EP05815745A EP1831199B1 (en) 2004-12-17 2005-12-14 MMP inhibitors
JP2007546609A JP2008524210A (ja) 2004-12-17 2005-12-14 メタロプロテイナーゼ阻害剤としての新規ヒダントイン誘導体
CA002590845A CA2590845A1 (en) 2004-12-17 2005-12-14 Novel hydantoin derivatives as metalloproteinase inhibitors
RU2007126746/04A RU2376301C2 (ru) 2004-12-17 2005-12-14 Новые производные гидантоина в качестве ингибиторов металлопротеиназ
AT05815745T ATE545642T1 (de) 2004-12-17 2005-12-14 Mmp-inhibitoren
MX2007007023A MX2007007023A (es) 2004-12-17 2005-12-14 Nuevos derivados de hidantoina como inhibidores de metaloproteinasa.
NZ555831A NZ555831A (en) 2004-12-17 2005-12-14 Novel hydantoin derivatives as metalloproteinase inhibitors
AU2005317286A AU2005317286B2 (en) 2004-12-17 2005-12-14 Novel hydantoin derivatives as metalloproteinase inhibitors
UAA200706657A UA90285C2 (ru) 2004-12-17 2005-12-14 Производные гидантоина, полезные как ингибиторы металлопротеиназ
ES05815745T ES2380670T3 (es) 2004-12-17 2005-12-14 Inhibidores de MMP
KR1020077013489A KR20070090924A (ko) 2004-12-17 2005-12-14 신규 화합물
BRPI0517035-4A BRPI0517035A (pt) 2004-12-17 2005-12-14 novos compostos
CNA2005800481778A CN101119987A (zh) 2004-12-17 2005-12-14 新化合物
MYPI20055915A MY147770A (en) 2004-12-17 2005-12-15 Novel compounds
ARP050105273A AR051795A1 (es) 2004-12-17 2005-12-15 Derivados de hidantoina inhibidores de metaloproteinasas
TW094144602A TW200635917A (en) 2004-12-17 2005-12-16 Novel compounds
SA05260409A SA05260409B1 (ar) 2004-12-17 2005-12-17 مثبطات جديده لانزيمات البروتينات المعدنية لهيدانتوين
IL183599A IL183599A (en) 2004-12-17 2007-05-31 Hydantoin derivatives, process for their preparation, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments
ZA200705075A ZA200705075B (en) 2004-12-17 2007-06-12 Novel hydantoin derivatives as metalloproteinase inhibitors
NO20073572A NO20073572L (no) 2004-12-17 2007-07-10 Nye forbindelser
US12/697,625 US20100256166A1 (en) 2004-12-17 2010-02-01 Novel Hydantoin Derivatives as Metalloproteinase Inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0403085A SE0403085D0 (sv) 2004-12-17 2004-12-17 Novel componds

Publications (1)

Publication Number Publication Date
SE0403085D0 true SE0403085D0 (sv) 2004-12-17

Family

ID=34075235

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0403085A SE0403085D0 (sv) 2004-12-17 2004-12-17 Novel componds

Country Status (23)

Country Link
US (2) US7655664B2 (sv)
EP (1) EP1831199B1 (sv)
JP (1) JP2008524210A (sv)
KR (1) KR20070090924A (sv)
CN (1) CN101119987A (sv)
AR (1) AR051795A1 (sv)
AT (1) ATE545642T1 (sv)
AU (1) AU2005317286B2 (sv)
BR (1) BRPI0517035A (sv)
CA (1) CA2590845A1 (sv)
ES (1) ES2380670T3 (sv)
IL (1) IL183599A (sv)
MX (1) MX2007007023A (sv)
MY (1) MY147770A (sv)
NO (1) NO20073572L (sv)
NZ (1) NZ555831A (sv)
RU (1) RU2376301C2 (sv)
SA (1) SA05260409B1 (sv)
SE (1) SE0403085D0 (sv)
TW (1) TW200635917A (sv)
UA (1) UA90285C2 (sv)
WO (1) WO2006065215A1 (sv)
ZA (1) ZA200705075B (sv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0100902D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0202539D0 (sv) 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
US7648992B2 (en) * 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0401762D0 (sv) 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds
SE0403085D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
SE0403086D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
CA2601076C (en) * 2005-03-16 2014-07-08 Advanced Metering Data Systems, L.L.C. Method, system, apparatus, and computer program product for determining a physical location of a sensor
EP1885369B1 (en) * 2005-05-04 2015-09-23 Evotec AG Fused heterocyclic compounds, and compositions and uses thereof
TW200740769A (en) 2006-03-16 2007-11-01 Astrazeneca Ab Novel process
TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds
KR101271219B1 (ko) * 2011-01-27 2013-06-07 광주과학기술원 신규한 하이단토인 유도체 및 이의 용도
JP6258508B2 (ja) * 2013-12-31 2018-01-10 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエIpsen Pharma S.A.S. 新規のイミダゾリジン−2,4−ジオン誘導体
WO2018117196A1 (ja) 2016-12-20 2018-06-28 大日本住友製薬株式会社 がん幹細胞を標的とする医薬
TW202202495A (zh) 2020-03-26 2022-01-16 匈牙利商羅特格登公司 作為gamma-胺基丁酸A受體次單元alpha 5受體調節劑之㖠啶及吡啶并〔3,4-c〕嗒𠯤衍生物
WO2023231964A1 (zh) * 2022-05-30 2023-12-07 赛诺哈勃药业(成都)有限公司 四氢萘啶衍生物在制备防治粘连相关疾病的药物中的应用

Family Cites Families (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2327890A (en) 1940-04-17 1943-08-24 Parke Davis & Co Substituted phenoxyalkyl ethers
US2745875A (en) 1953-06-30 1956-05-15 Hoechst Ag Preparation of nu-acylamino-phenylpropane diols
US3452040A (en) 1966-01-05 1969-06-24 American Home Prod 5,5-disubstituted hydantoins
US3529019A (en) 1968-04-23 1970-09-15 Colgate Palmolive Co Alkylaryloxy alanines
US3849574A (en) 1971-05-24 1974-11-19 Colgate Palmolive Co Alpha-substituted-beta-arylthioalkyl amino-acids,for increasing heart rate
US4315031A (en) 1977-09-01 1982-02-09 Science Union Et Cie Thiosubstituted amino acids
GB1601310A (en) 1978-05-23 1981-10-28 Lilly Industries Ltd Aryl hydantoins
US4529019A (en) * 1981-07-28 1985-07-16 The Crowell Corporation Safe tire inflator
JPS6172762A (ja) 1984-09-17 1986-04-14 Kanegafuchi Chem Ind Co Ltd 光学活性ヒダントイン類の製造法
JPS61212292A (ja) 1985-03-19 1986-09-20 Mitsui Toatsu Chem Inc D−α−アミノ酸の製造方法
CA1325222C (en) 1985-08-23 1993-12-14 Lederle (Japan), Ltd. Process for producing 4-biphenylylacetic acid
GB8618559D0 (en) 1986-07-30 1986-09-10 Genetics Int Inc Rhodococcus bacterium
JPH0279879A (ja) 1988-09-17 1990-03-20 Canon Inc 画像形成装置
US4983771A (en) 1989-09-18 1991-01-08 Hexcel Corporation Method for resolution of D,L-alpha-phenethylamine with D(-)mandelic acid
NL9000386A (nl) 1990-02-16 1991-09-16 Stamicarbon Werkwijze voor de bereiding van optisch aktief aminozuuramide.
DK161690D0 (da) 1990-07-05 1990-07-05 Novo Nordisk As Fremgangsmaade til fremstilling af enantiomere forbindelser
IL99957A0 (en) 1990-11-13 1992-08-18 Merck & Co Inc Piperidinylcamphorsulfonyl oxytocin antagonists and pharmaceutical compositions containing them
PH31245A (en) 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5308853A (en) 1991-12-20 1994-05-03 Warner-Lambert Company Substituted-5-methylidene hydantoins with AT1 receptor antagonist properties
US5246943A (en) 1992-05-19 1993-09-21 Warner-Lambert Company Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
NL9201230A (nl) 1992-07-09 1994-02-01 Dsm Nv Werkwijze voor de bereiding van optisch aktief methionineamide.
EP0640594A1 (en) 1993-08-23 1995-03-01 Fujirebio Inc. Hydantoin derivative as metalloprotease inhibitor
JPH09505310A (ja) 1993-11-16 1997-05-27 メルク エンド カンパニー インコーポレーテッド ピペリジンショウノウスルホニルオキシトシン拮抗剤
EP0709375B1 (en) 1994-10-25 2005-05-18 AstraZeneca AB Therapeutic heterocycles
ZA96211B (en) 1995-01-12 1996-07-26 Teva Pharma Compositions containing and methods of using 1- aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
US5863949A (en) 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
US6166041A (en) 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
WO1997019075A1 (en) 1995-11-22 1997-05-29 Darwin Discovery Limited Mercaptoalkylpeptidyl compounds having an imidazole substituent and their use as inhibitors of matrix metalloproteinases (mmp) and/or tumour necrosis factor (tnf)
GB9616643D0 (en) 1996-08-08 1996-09-25 Chiroscience Ltd Compounds
US5919790A (en) 1996-10-11 1999-07-06 Warner-Lambert Company Hydroxamate inhibitors of interleukin-1β converting enzyme
ATE212619T1 (de) 1996-10-22 2002-02-15 Upjohn Co Alpha-amino sulfonyl hydroxamsäure als matrix metalloproteinase inhibitoren
HUP0003362A3 (en) 1997-05-06 2001-04-28 Novo Nordisk As Piperidine derivatives and pharmaceutical compositions containing them
DE59802394D1 (de) 1997-05-09 2002-01-24 Hoechst Ag Substituierte Diaminocarbonsäuren
TR199903287T2 (xx) 1997-07-31 2000-09-21 Abbott Laboratories Matriks metaloproteinazlar�n�n ters hidroksamat inhibit�rleri.
TW514634B (en) 1997-10-14 2002-12-21 Lilly Co Eli Process to make chiral compounds
KR100609926B1 (ko) 1997-11-12 2006-08-04 다윈 디스커버리 리미티드 엠엠피와 티엔에프 억제 활성을 갖는 히드록삼산 및카르복실산 유도체
KR20010040698A (ko) 1998-02-04 2001-05-15 한스 루돌프 하우스, 헨리테 브룬너, 베아트리체 귄터 기질 분해 메탈로프로테이나제를 억제하는 술포닐아미노유도체
US6329418B1 (en) 1998-04-14 2001-12-11 The Procter & Gamble Company Substituted pyrrolidine hydroxamate metalloprotease inhibitors
AU4074799A (en) 1998-05-14 1999-11-29 Du Pont Pharmaceuticals Company Substituted aryl hydroxamic acids as metalloproteinase inhibitors
JP2002516904A (ja) 1998-06-03 2002-06-11 ジーピーアイ ニル ホールディングス インコーポレイテッド N−複素環式カルボン酸またはカルボン酸等配電子体のn−結合スルホンアミド
JP2002518368A (ja) 1998-06-17 2002-06-25 デュポン ファーマシューティカルズ カンパニー メタロプロテイナーゼ阻害剤としての環式ヒドロキサム酸類
FR2782082B3 (fr) 1998-08-05 2000-09-22 Sanofi Sa Formes cristallines de (r)-(+)-n-[[3-[1-benzoyl-3-(3,4- dichlorophenyl)piperidin-3-yl]prop-1-yl]-4-phenylpiperidin-4 -yl]-n-methylacetamide (osanetant) et procede pour la preparation dudit compose
US6339101B1 (en) 1998-08-14 2002-01-15 Gpi Nil Holdings, Inc. N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders
JP2002523492A (ja) 1998-08-29 2002-07-30 ブリティッシュ バイオテック ファーマシューティカルズ リミテッド タンパク質分解酵素阻害剤としてのヒドロキサム酸誘導体
GB9919776D0 (en) 1998-08-31 1999-10-27 Zeneca Ltd Compoujnds
DE69907238T2 (de) 1998-10-07 2003-11-06 Yazaki Corp Sol-gel verfahren unter verwendung poröser formen
DK1004578T3 (da) 1998-11-05 2004-06-28 Pfizer Prod Inc 5-oxo-pyrrolidin-2-carboxylsyrehydroxamidderivater
EA200100675A1 (ru) 1998-12-18 2001-12-24 Аксис Фармасьютикалз, Инк. Ингибиторы протеазы
EP1150975A1 (en) 1998-12-31 2001-11-07 Aventis Pharmaceuticals Inc. 1-carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of mmp-12
US6340691B1 (en) 1999-01-27 2002-01-22 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors
WO2000044770A1 (fr) 1999-01-28 2000-08-03 Chugai Seiyaku Kabushiki Kaisha Derives phenethylamine substitues
US6294694B1 (en) 1999-06-04 2001-09-25 Wisconsin Alumni Research Foundation Matrix metalloproteinase inhibitors and method of using same
GB9916562D0 (en) 1999-07-14 1999-09-15 Pharmacia & Upjohn Spa 3-Arylsulfonyl-2-(substituted-methyl) propanoic acid derivatives as matrix metalloproteinase inhibitora
US20020006920A1 (en) 1999-07-22 2002-01-17 Robinson Ralph Pelton Arylsulfonylamino hydroxamic acid derivatives
US6266453B1 (en) 1999-07-26 2001-07-24 Computerized Medical Systems, Inc. Automated image fusion/alignment system and method
DE60026404T2 (de) 1999-08-02 2006-10-19 F. Hoffmann-La Roche Ag Verfahren zur Herstellung von Benzothiophen-Derivaten
EA005373B1 (ru) 1999-08-12 2005-02-24 Фармация Италия С.П.А. Производные 3(5)-аминопиразола, способ их получения и их применение в качестве противоопухолевых средств
SE9904044D0 (sv) 1999-11-09 1999-11-09 Astra Ab Compounds
US6525202B2 (en) 2000-07-17 2003-02-25 Wyeth Cyclic amine phenyl beta-3 adrenergic receptor agonists
US20020065219A1 (en) 2000-08-15 2002-05-30 Naidu B. Narasimhulu Water soluble thiazolyl peptide derivatives
US20020091107A1 (en) 2000-09-08 2002-07-11 Madar David J. Oxazolidinone antibacterial agents
EP1191024A1 (en) 2000-09-22 2002-03-27 Harald Tschesche Thiadiazines and their use as inhibitors of metalloproteinases
BR0208105A (pt) * 2001-03-15 2004-03-09 Astrazeneca Ab Inibidores de metaloproteinase
SE0100903D0 (sv) 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0100902D0 (sv) 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
CA2447475A1 (en) 2001-05-25 2002-12-05 Chu-Biao Xue Hydantion derivatives as inhibitors of matrix metalloproteinases
GB0114004D0 (en) 2001-06-08 2001-08-01 Glaxo Group Ltd Chemical compounds
SE0103710D0 (sv) 2001-11-07 2001-11-07 Astrazeneca Ab Compounds
KR20050010826A (ko) 2002-06-05 2005-01-28 가부시키가이샤 가네카 광학 활성 α-메틸시스테인 유도체의 제조 방법
SE0202539D0 (sv) 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
SE0202693D0 (sv) * 2002-09-11 2002-09-11 Astrazeneca Ab Compounds
GB0221246D0 (en) 2002-09-13 2002-10-23 Astrazeneca Ab Compounds
WO2004033632A2 (en) * 2002-10-04 2004-04-22 Bristol-Myers Squibb Company Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or tnf-alpha converting enzyme (tace)
US7132432B2 (en) * 2003-06-05 2006-11-07 Bristol-Myers Squibb Company Hydantoin derivatives as inhibitors of tumor necrosis factor-alpha converting enzyme (TACE)
US20040266832A1 (en) 2003-06-26 2004-12-30 Li Zheng J. Crystal forms of 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl pyridine
TWI220073B (en) 2003-07-24 2004-08-01 Au Optronics Corp Method for manufacturing polysilicon film
SE0401762D0 (sv) 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds
SE0401763D0 (sv) 2004-07-05 2004-07-05 Astrazeneca Ab Compounds
US7648992B2 (en) 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0403086D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
SE0403085D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
TW200740769A (en) 2006-03-16 2007-11-01 Astrazeneca Ab Novel process
TW200831488A (en) 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds

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KR20070090924A (ko) 2007-09-06
US7655664B2 (en) 2010-02-02
ATE545642T1 (de) 2012-03-15
US20100256166A1 (en) 2010-10-07
ZA200705075B (en) 2008-12-31
MY147770A (en) 2013-01-31
ES2380670T3 (es) 2012-05-17
UA90285C2 (ru) 2010-04-26
IL183599A0 (en) 2007-09-20
RU2007126746A (ru) 2009-01-27
AU2005317286A1 (en) 2006-06-22
CA2590845A1 (en) 2006-06-22
AU2005317286B2 (en) 2009-02-05
US20080293743A1 (en) 2008-11-27
EP1831199B1 (en) 2012-02-15
TW200635917A (en) 2006-10-16
AR051795A1 (es) 2007-02-07
EP1831199A1 (en) 2007-09-12
NO20073572L (no) 2007-09-12
CN101119987A (zh) 2008-02-06
RU2376301C2 (ru) 2009-12-20
MX2007007023A (es) 2007-09-11
JP2008524210A (ja) 2008-07-10
IL183599A (en) 2012-02-29
BRPI0517035A (pt) 2008-09-30
NZ555831A (en) 2011-01-28
WO2006065215A1 (en) 2006-06-22
SA05260409B1 (ar) 2009-03-14

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