ATE545642T1 - Mmp-inhibitoren - Google Patents

Mmp-inhibitoren

Info

Publication number
ATE545642T1
ATE545642T1 AT05815745T AT05815745T ATE545642T1 AT E545642 T1 ATE545642 T1 AT E545642T1 AT 05815745 T AT05815745 T AT 05815745T AT 05815745 T AT05815745 T AT 05815745T AT E545642 T1 ATE545642 T1 AT E545642T1
Authority
AT
Austria
Prior art keywords
mmp inhibitors
mmp
inhibitors
Prior art date
Application number
AT05815745T
Other languages
English (en)
Inventor
Balint Gabos
Michael Lundkvist
Af Rosenschoeld Magnus Munck
Igor Shamovsky
Pavol Zlatoidsky
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE545642T1 publication Critical patent/ATE545642T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT05815745T 2004-12-17 2005-12-14 Mmp-inhibitoren ATE545642T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0403085A SE0403085D0 (sv) 2004-12-17 2004-12-17 Novel componds
PCT/SE2005/001917 WO2006065215A1 (en) 2004-12-17 2005-12-14 Novel compounds

Publications (1)

Publication Number Publication Date
ATE545642T1 true ATE545642T1 (de) 2012-03-15

Family

ID=34075235

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05815745T ATE545642T1 (de) 2004-12-17 2005-12-14 Mmp-inhibitoren

Country Status (23)

Country Link
US (2) US7655664B2 (de)
EP (1) EP1831199B1 (de)
JP (1) JP2008524210A (de)
KR (1) KR20070090924A (de)
CN (1) CN101119987A (de)
AR (1) AR051795A1 (de)
AT (1) ATE545642T1 (de)
AU (1) AU2005317286B2 (de)
BR (1) BRPI0517035A (de)
CA (1) CA2590845A1 (de)
ES (1) ES2380670T3 (de)
IL (1) IL183599A (de)
MX (1) MX2007007023A (de)
MY (1) MY147770A (de)
NO (1) NO20073572L (de)
NZ (1) NZ555831A (de)
RU (1) RU2376301C2 (de)
SA (1) SA05260409B1 (de)
SE (1) SE0403085D0 (de)
TW (1) TW200635917A (de)
UA (1) UA90285C2 (de)
WO (1) WO2006065215A1 (de)
ZA (1) ZA200705075B (de)

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SE0202539D0 (sv) 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
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US7648992B2 (en) * 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0403085D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
SE0403086D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
WO2006099598A2 (en) * 2005-03-16 2006-09-21 Sensus Metering Systems Inc. Determining a physical location of a sensor
US7745451B2 (en) * 2005-05-04 2010-06-29 Renovis, Inc. Tetrahydronaphthyridine and tetrahydropyrido[4,3-d]pyrimidine compounds and compositions thereof useful in the treatment of conditions associated with neurological and inflammatory disorders and dysfunctions
TW200740769A (en) * 2006-03-16 2007-11-01 Astrazeneca Ab Novel process
TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds
KR101271219B1 (ko) * 2011-01-27 2013-06-07 광주과학기술원 신규한 하이단토인 유도체 및 이의 용도
EP3089974B1 (de) * 2013-12-31 2019-02-20 Ipsen Pharma S.A.S. Neuartige imidazolidin-2,4-dion-derivate
WO2018117196A1 (ja) 2016-12-20 2018-06-28 大日本住友製薬株式会社 がん幹細胞を標的とする医薬
TWI901650B (zh) * 2020-03-26 2025-10-21 匈牙利商羅特格登公司 啶及吡啶并〔３，４－ｃ〕嗒衍生物
WO2023127883A1 (ja) 2021-12-28 2023-07-06 日本新薬株式会社 インダゾール化合物及び医薬
KR20250011204A (ko) * 2022-05-30 2025-01-21 시노허브 파마슈티컬 씨오., 엘티디 유착 관련 질환을 예방 치료하는 약물의 제조에서 테트라히드로나프티리딘 유도체의 응용

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SE0403085D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
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TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
RU2376301C2 (ru) 2009-12-20
EP1831199A1 (de) 2007-09-12
IL183599A0 (en) 2007-09-20
IL183599A (en) 2012-02-29
SE0403085D0 (sv) 2004-12-17
US20100256166A1 (en) 2010-10-07
ES2380670T3 (es) 2012-05-17
NO20073572L (no) 2007-09-12
AU2005317286B2 (en) 2009-02-05
MY147770A (en) 2013-01-31
CA2590845A1 (en) 2006-06-22
CN101119987A (zh) 2008-02-06
MX2007007023A (es) 2007-09-11
KR20070090924A (ko) 2007-09-06
EP1831199B1 (de) 2012-02-15
US20080293743A1 (en) 2008-11-27
NZ555831A (en) 2011-01-28
SA05260409B1 (ar) 2009-03-14
WO2006065215A1 (en) 2006-06-22
US7655664B2 (en) 2010-02-02
TW200635917A (en) 2006-10-16
AR051795A1 (es) 2007-02-07
RU2007126746A (ru) 2009-01-27
BRPI0517035A (pt) 2008-09-30
AU2005317286A1 (en) 2006-06-22
ZA200705075B (en) 2008-12-31
JP2008524210A (ja) 2008-07-10
UA90285C2 (ru) 2010-04-26

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