ATE433449T1 - Kinaseinhibitoren - Google Patents

Kinaseinhibitoren

Info

Publication number
ATE433449T1
ATE433449T1 AT05704878T AT05704878T ATE433449T1 AT E433449 T1 ATE433449 T1 AT E433449T1 AT 05704878 T AT05704878 T AT 05704878T AT 05704878 T AT05704878 T AT 05704878T AT E433449 T1 ATE433449 T1 AT E433449T1
Authority
AT
Austria
Prior art keywords
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
AT05704878T
Other languages
English (en)
Inventor
Rosanne Bonjouklian
Chafiq Hamdouchi
Chuan Shih
Dios Alfonso De
Prado Miriam Del
Aguado Carlos Jaramillo
Pramila Kotiyan
Mary Mader
Sheila Selgas
Concepcion Sanchez-Martinez
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34837430&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE433449(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE433449T1 publication Critical patent/ATE433449T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05704878T 2004-01-30 2005-01-25 Kinaseinhibitoren ATE433449T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54083004P 2004-01-30 2004-01-30
PCT/US2005/000025 WO2005075478A1 (en) 2004-01-30 2005-01-25 Kinase inhibitors

Publications (1)

Publication Number Publication Date
ATE433449T1 true ATE433449T1 (de) 2009-06-15

Family

ID=34837430

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05704878T ATE433449T1 (de) 2004-01-30 2005-01-25 Kinaseinhibitoren

Country Status (25)

Country Link
US (2) US7582652B2 (de)
EP (1) EP1713805B1 (de)
CN (1) CN100516064C (de)
AR (1) AR047466A1 (de)
AT (1) ATE433449T1 (de)
AU (1) AU2005210459B2 (de)
CA (1) CA2559128C (de)
CY (1) CY1109234T1 (de)
DE (1) DE602005014848D1 (de)
DK (1) DK1713805T3 (de)
DO (1) DOP2005000010A (de)
ES (1) ES2326819T3 (de)
IL (1) IL178103A (de)
MY (1) MY143516A (de)
NZ (1) NZ549780A (de)
PE (1) PE20050689A1 (de)
PL (1) PL1713805T3 (de)
PT (1) PT1713805E (de)
RU (1) RU2348635C2 (de)
SI (1) SI1713805T1 (de)
SV (1) SV2006002001A (de)
TW (1) TWI332003B (de)
UA (1) UA85505C2 (de)
WO (1) WO2005075478A1 (de)
ZA (1) ZA200607648B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI332003B (en) * 2004-01-30 2010-10-21 Lilly Co Eli Kinase inhibitors
US7776869B2 (en) * 2004-10-18 2010-08-17 Amgen Inc. Heteroaryl-substituted alkyne compounds and method of use
EP1992344A1 (de) 2007-05-18 2008-11-19 Institut Curie P38 Alpha als therapeutisches Target für Erkrankungen, die mit einer FGFR3- Mutation assoziiert sind
EA025281B9 (ru) * 2010-05-17 2017-08-31 Инкозен Терапьютикс Пвт. Лтд. СОЕДИНЕНИЯ 3,5-ДИЗАМЕЩЕННОГО-3H-ИМИДАЗО[4,5-b]ПИРИДИНА И 3,5-ДИЗАМЕЩЕННОГО-3H-[1,2,3]ТРИАЗОЛО[4,5-b]ПИРИДИНА КАК МОДУЛЯТОРЫ ПРОТЕИНКИНАЗ
TWI410425B (zh) * 2010-12-03 2013-10-01 Lilly Co Eli 唑并［５，４－ｂ］吡啶－５－基化合物
LT2780011T (lt) 2011-11-11 2018-05-10 Eli Lilly And Company Kombinuota kiaušidžių vėžio terapija
JP2015533859A (ja) * 2012-07-23 2015-11-26 アクロン大学 有機修飾モンモリロナイトを含有するポリイソブチレン系ポリウレタン
US9067914B1 (en) 2013-12-10 2015-06-30 Genzyme Corporation Tropomyosin-related kinase (TRK) inhibitors
MA40698A3 (fr) 2014-12-18 2020-01-31 Genzyme Corp Formulations pharmaceutiques d'inhibiteurs de kinase associée à la tropomyosine (trk)
MA41179A (fr) 2014-12-19 2017-10-24 Cancer Research Tech Ltd Composés inhibiteurs de parg
SG11201705821XA (en) * 2015-03-02 2017-08-30 Rigel Pharmaceuticals Inc TGF-ß INHIBITORS
CN114748622B (zh) 2017-10-05 2024-09-24 弗尔康医疗公司 P38激酶抑制剂降低dux4和下游基因表达以用于治疗fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
US10899869B2 (en) 2019-01-24 2021-01-26 The University Of Akron Glycerol containing polyurethanes and polyurethane nanocomposites
TW202112368A (zh) 2019-06-13 2021-04-01 荷蘭商法西歐知識產權股份有限公司 用於治療有關dux4表現之疾病的抑制劑組合
TW202345809A (zh) 2022-03-23 2023-12-01 美商愛德亞生物科學公司 作為parg抑制劑之經哌取代的吲唑化合物

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9300141A (es) * 1992-01-13 1994-07-29 Smithkline Beecham Corp Compuestos de imidazol novedosos, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen.
DE19503806A1 (de) * 1994-02-11 1995-08-17 Bernhardt Apparatebau Gmbh Co Vorrichtung zum Aufblasen eines Behälters oder eines Schwimmkörpers, insbesondere einer Schwimmweste
US5620999A (en) 1994-07-28 1997-04-15 Weier; Richard M. Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
US6426360B1 (en) * 1994-07-28 2002-07-30 G D Searle & Co. 4,5-substituted imidazolyl compounds for the treatment of inflammation
US5717100A (en) * 1995-10-06 1998-02-10 Merck & Co., Inc. Substituted imidazoles having anti-cancer and cytokine inhibitory activity
WO1998007425A1 (en) * 1996-08-21 1998-02-26 Smithkline Beecham Corporation Imidazole compounds, compositions and use
US6087496A (en) * 1998-05-22 2000-07-11 G. D. Searle & Co. Substituted pyrazoles suitable as p38 kinase inhibitors
US6180632B1 (en) * 1997-05-28 2001-01-30 Aventis Pharmaceuticals Products Inc. Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
AU8167398A (en) 1997-06-30 1999-01-19 Temple University - Of The Commonwealth System Of Higher Education Method for treating vulvar vestibulitis
AR016294A1 (es) * 1997-07-02 2001-07-04 Smithkline Beecham Corp Compuesto de imidazol sustituido, composicion farmaceutica que la contiene, su uso en la fabricacion de un medicamento y procedimiento para supreparacion
UA62972C2 (en) * 1997-07-03 2004-01-15 Application of imidazopyrimidins and imidazopyridins for the treatment of neural disorders
AU1924699A (en) * 1997-12-19 1999-07-12 Smithkline Beecham Corporation Compounds of heteroaryl substituted imidazole, their pharmaceutical compositionsand uses
US6207687B1 (en) 1998-07-31 2001-03-27 Merck & Co., Inc. Substituted imidazoles having cytokine inhibitory activity
US6291457B1 (en) 1999-07-01 2001-09-18 Merck & Co., Inc. Compounds having cytokine inhibitory activity
ATE311385T1 (de) * 1999-10-27 2005-12-15 Novartis Pharma Gmbh Thiazol und imidazo(4,5-b)pyridin verbindungen und ihre verwendung als pharmazeutika
GB0007405D0 (en) * 2000-03-27 2000-05-17 Smithkline Beecham Corp Compounds
BR0207990A (pt) 2001-03-09 2004-04-27 Pfizer Prod Inc Compostos antinflamatórios de triazolopiridinas
AU2002246397B2 (en) 2001-04-16 2005-03-24 Tanabe Seiyaku Co., Ltd. Imidazole, thiazole and oxazole derivatives and their use for the manufacture of a medicament for the treatment and/or prevention of pollakiuria or urinary incontinence
EP1467981A1 (de) 2002-01-25 2004-10-20 Kylix Pharmaceuticals B.V. 4-(hetero)aryl-substituierte (thia-/oxa-/pyra)zole zur inhibierung von tie-2
KR20050067383A (ko) 2002-08-06 2005-07-01 아스트라제네카 아베 Ｔｉｅ2(ｔｅｋ) 활성을 갖는 축합 피리딘 및 피리미딘
TWI332003B (en) * 2004-01-30 2010-10-21 Lilly Co Eli Kinase inhibitors

Also Published As

Publication number Publication date
ES2326819T3 (es) 2009-10-20
WO2005075478A1 (en) 2005-08-18
US20090318443A1 (en) 2009-12-24
PT1713805E (pt) 2009-08-20
UA85505C2 (en) 2009-01-26
CN100516064C (zh) 2009-07-22
US20090036445A1 (en) 2009-02-05
TW200526660A (en) 2005-08-16
AU2005210459A1 (en) 2005-08-18
CY1109234T1 (el) 2014-07-02
RU2006138606A (ru) 2008-05-10
MY143516A (en) 2011-05-31
RU2348635C2 (ru) 2009-03-10
AU2005210459B2 (en) 2010-10-21
HK1100141A1 (en) 2007-09-07
PL1713805T3 (pl) 2009-10-30
CA2559128A1 (en) 2005-08-18
TWI332003B (en) 2010-10-21
SI1713805T1 (sl) 2009-10-31
AR047466A1 (es) 2006-01-18
IL178103A (en) 2011-04-28
SV2006002001A (es) 2006-02-15
DE602005014848D1 (de) 2009-07-23
PE20050689A1 (es) 2005-09-27
DK1713805T3 (da) 2009-08-17
EP1713805B1 (de) 2009-06-10
DOP2005000010A (es) 2005-11-15
ZA200607648B (en) 2008-06-25
NZ549780A (en) 2010-01-29
US7582652B2 (en) 2009-09-01
CA2559128C (en) 2013-04-16
EP1713805A1 (de) 2006-10-25
CN1938302A (zh) 2007-03-28

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