DK2013175T5 - p38 Map-kinase-inhibitorer - Google Patents
p38 Map-kinase-inhibitorer Download PDFInfo
- Publication number
- DK2013175T5 DK2013175T5 DK07732629.6T DK07732629T DK2013175T5 DK 2013175 T5 DK2013175 T5 DK 2013175T5 DK 07732629 T DK07732629 T DK 07732629T DK 2013175 T5 DK2013175 T5 DK 2013175T5
- Authority
- DK
- Denmark
- Prior art keywords
- kinase inhibitors
- map kinase
- map
- inhibitors
- kinase
- Prior art date
Links
- 239000002829 mitogen activated protein kinase inhibitor Substances 0.000 title 1
- 102000002574 p38 Mitogen-Activated Protein Kinases Human genes 0.000 title 1
- 108010068338 p38 Mitogen-Activated Protein Kinases Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0608855A GB0608855D0 (en) | 2006-05-04 | 2006-05-04 | Inhibitors of MAP kinase enzymes |
GB0613914A GB0613914D0 (en) | 2006-07-13 | 2006-07-13 | Inhibitors of p38 map kinase |
PCT/GB2007/001596 WO2007129040A1 (en) | 2006-05-04 | 2007-05-01 | p38 MAP KINASE INHIBITORS |
Publications (2)
Publication Number | Publication Date |
---|---|
DK2013175T3 DK2013175T3 (da) | 2017-02-20 |
DK2013175T5 true DK2013175T5 (da) | 2020-12-21 |
Family
ID=38268953
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07732629.6T DK2013175T5 (da) | 2006-05-04 | 2007-05-01 | p38 Map-kinase-inhibitorer |
Country Status (15)
Country | Link |
---|---|
US (1) | US8044211B2 (da) |
EP (1) | EP2013175B9 (da) |
JP (1) | JP5340918B2 (da) |
KR (1) | KR101429780B1 (da) |
CN (1) | CN102942520B (da) |
AU (1) | AU2007246869B2 (da) |
BR (1) | BRPI0711310B8 (da) |
CA (1) | CA2650970C (da) |
CY (1) | CY1118518T1 (da) |
DK (1) | DK2013175T5 (da) |
ES (1) | ES2605727T3 (da) |
HU (1) | HUE033281T2 (da) |
NZ (1) | NZ573348A (da) |
PT (1) | PT2013175T (da) |
WO (1) | WO2007129040A1 (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0619753D0 (en) | 2006-10-06 | 2006-11-15 | Chroma Therapeutics Ltd | Enzyme inhibitors |
WO2008053131A1 (en) * | 2006-10-30 | 2008-05-08 | Chroma Therapeutics Ltd. | Hydroxamates as inhibitors of histone deacetylase |
AU2008269516B2 (en) | 2007-06-27 | 2011-11-17 | Astrazeneca Ab | Pyrazinone derivatives and their use in the treatment of lung diseases |
WO2009060160A1 (en) * | 2007-11-07 | 2009-05-14 | Chroma Therapeutics Ltd. | P38 map kinase inhibitors |
GB0803747D0 (en) | 2008-02-29 | 2008-04-09 | Martin | Enzyme and receptor modulation |
EP2245012B1 (en) * | 2008-02-29 | 2013-07-03 | Chroma Therapeutics Limited | Inhibitors of p38 map kinase |
CN102099036B (zh) | 2008-06-03 | 2015-05-27 | 英特芒尼公司 | 用于治疗炎性疾患和纤维化疾患的化合物和方法 |
AR073711A1 (es) | 2008-10-01 | 2010-11-24 | Astrazeneca Ab | Derivados de isoquinolina |
GB0903480D0 (en) | 2009-02-27 | 2009-04-08 | Chroma Therapeutics Ltd | Enzyme Inhibitors |
GB201211310D0 (en) | 2012-06-26 | 2012-08-08 | Chroma Therapeutics Ltd | CSF-1R kinase inhibitors |
AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
SG10201708166SA (en) * | 2012-10-17 | 2017-11-29 | Macrophage Pharma Ltd | Tert-Butyl N-[2-{4-[6-Amino-5-(2,4-Difluorobenzoyl)-2-Oxopyridin-1(2H)-yl]-3,5-Difluorophenyl}Ethyl]-L-Alaninate Or A Salt, Hydrate Or Solvate Thereof |
GB201306901D0 (en) * | 2013-04-16 | 2013-05-29 | Chroma Therapeutics Ltd | Combination |
CN110452216B (zh) | 2014-04-02 | 2022-08-26 | 英特穆恩公司 | 抗纤维化吡啶酮类 |
GB201713975D0 (en) | 2017-08-31 | 2017-10-18 | Macrophage Pharma Ltd | Medical use |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005526068A (ja) * | 2002-03-14 | 2005-09-02 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | 抗炎症剤としての単環式アロイルピリジノン類 |
EP1964577B1 (en) * | 2005-05-05 | 2016-04-13 | GlaxoSmithKline Intellectual Property Development Limited | Alpha aminoacid ester-drug conjugates hydrolysable by carboxylesterase |
EP2245012B1 (en) * | 2008-02-29 | 2013-07-03 | Chroma Therapeutics Limited | Inhibitors of p38 map kinase |
-
2007
- 2007-05-01 WO PCT/GB2007/001596 patent/WO2007129040A1/en active Application Filing
- 2007-05-01 BR BRPI0711310A patent/BRPI0711310B8/pt not_active IP Right Cessation
- 2007-05-01 EP EP07732629.6A patent/EP2013175B9/en active Active
- 2007-05-01 NZ NZ573348A patent/NZ573348A/en not_active IP Right Cessation
- 2007-05-01 JP JP2009508455A patent/JP5340918B2/ja not_active Expired - Fee Related
- 2007-05-01 AU AU2007246869A patent/AU2007246869B2/en not_active Ceased
- 2007-05-01 ES ES07732629.6T patent/ES2605727T3/es active Active
- 2007-05-01 PT PT77326296T patent/PT2013175T/pt unknown
- 2007-05-01 US US12/299,333 patent/US8044211B2/en not_active Expired - Fee Related
- 2007-05-01 HU HUE07732629A patent/HUE033281T2/en unknown
- 2007-05-01 KR KR1020087029538A patent/KR101429780B1/ko active IP Right Grant
- 2007-05-01 DK DK07732629.6T patent/DK2013175T5/da active
- 2007-05-01 CA CA2650970A patent/CA2650970C/en not_active Expired - Fee Related
- 2007-05-01 CN CN201210457450.4A patent/CN102942520B/zh not_active Expired - Fee Related
-
2017
- 2017-01-02 CY CY20171100002T patent/CY1118518T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN102942520B (zh) | 2015-03-04 |
WO2007129040A1 (en) | 2007-11-15 |
BRPI0711310B8 (pt) | 2021-05-25 |
ES2605727T3 (es) | 2017-03-16 |
KR101429780B1 (ko) | 2014-08-18 |
US8044211B2 (en) | 2011-10-25 |
BRPI0711310A2 (pt) | 2011-12-06 |
HUE033281T2 (en) | 2017-11-28 |
EP2013175B1 (en) | 2016-11-09 |
ES2605727T9 (es) | 2020-12-11 |
AU2007246869A1 (en) | 2007-11-15 |
JP2009535385A (ja) | 2009-10-01 |
EP2013175B9 (en) | 2020-11-11 |
CN102942520A (zh) | 2013-02-27 |
AU2007246869B2 (en) | 2012-10-18 |
CY1118518T1 (el) | 2017-07-12 |
CA2650970A1 (en) | 2007-11-15 |
EP2013175A1 (en) | 2009-01-14 |
NZ573348A (en) | 2012-01-12 |
DK2013175T3 (da) | 2017-02-20 |
US20090099185A1 (en) | 2009-04-16 |
KR20090014187A (ko) | 2009-02-06 |
JP5340918B2 (ja) | 2013-11-13 |
BRPI0711310B1 (pt) | 2020-12-15 |
PT2013175T (pt) | 2017-02-14 |
CA2650970C (en) | 2014-09-16 |
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