AU2002308515C1 - Pentapeptide compounds and uses related thereto - Google Patents

Pentapeptide compounds and uses related thereto Download PDF

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Publication number
AU2002308515C1
AU2002308515C1 AU2002308515A AU2002308515A AU2002308515C1 AU 2002308515 C1 AU2002308515 C1 AU 2002308515C1 AU 2002308515 A AU2002308515 A AU 2002308515A AU 2002308515 A AU2002308515 A AU 2002308515A AU 2002308515 C1 AU2002308515 C1 AU 2002308515C1
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AU
Australia
Prior art keywords
lower alkyl
compound
hydrogen
pharmaceutically acceptable
solvate
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AU2002308515A
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AU2002308515A1 (en
AU2002308515B2 (en
Inventor
Svetlana Doronina
Peter D. Senter
Brian E. Toki
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Seagen Inc
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Seagen Inc
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Priority claimed from US09/845,786 external-priority patent/US20030083263A1/en
Application filed by Seagen Inc filed Critical Seagen Inc
Publication of AU2002308515A1 publication Critical patent/AU2002308515A1/en
Application granted granted Critical
Publication of AU2002308515B2 publication Critical patent/AU2002308515B2/en
Publication of AU2002308515C1 publication Critical patent/AU2002308515C1/en
Assigned to SEAGEN INC. reassignment SEAGEN INC. Request to Amend Deed and Register Assignors: SEATTLE GENETICS, INC.
Active legal-status Critical Current
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002308515A 2001-04-30 2002-04-30 Pentapeptide compounds and uses related thereto Active 2027-04-30 AU2002308515C1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/845,786 2001-04-30
US09/845,786 US20030083263A1 (en) 2001-04-30 2001-04-30 Pentapeptide compounds and uses related thereto
US10/001,191 2001-11-01
US10/001,191 US6884869B2 (en) 2001-04-30 2001-11-01 Pentapeptide compounds and uses related thereto
PCT/US2002/013435 WO2002088172A2 (en) 2001-04-30 2002-04-30 Pentapeptide compounds and uses related thereto

Publications (3)

Publication Number Publication Date
AU2002308515A1 AU2002308515A1 (en) 2003-04-17
AU2002308515B2 AU2002308515B2 (en) 2007-09-06
AU2002308515C1 true AU2002308515C1 (en) 2008-07-10

Family

ID=26668695

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002308515A Active 2027-04-30 AU2002308515C1 (en) 2001-04-30 2002-04-30 Pentapeptide compounds and uses related thereto

Country Status (6)

Country Link
US (2) US6884869B2 (US07794700-20100914-C00152.png)
EP (1) EP1390393A4 (US07794700-20100914-C00152.png)
JP (1) JP4095444B2 (US07794700-20100914-C00152.png)
AU (1) AU2002308515C1 (US07794700-20100914-C00152.png)
CA (1) CA2445875C (US07794700-20100914-C00152.png)
WO (1) WO2002088172A2 (US07794700-20100914-C00152.png)

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