TWI691509B - Ｐｄ-１結合分子和其使用方法 - Google Patents

Ｐｄ-１結合分子和其使用方法 Download PDF

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TWI691509B
TWI691509B TW105123965A TW105123965A TWI691509B TW I691509 B TWI691509 B TW I691509B TW 105123965 A TW105123965 A TW 105123965A TW 105123965 A TW105123965 A TW 105123965A TW I691509 B TWI691509 B TW I691509B
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mab
cancer
domain
seq
binding
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TW105123965A
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TW201710292A (zh
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坎帕納 尚
道格拉斯 史密斯
羅斯 拉莫特莫斯
萊斯利 強生
保羅 摩爾
愛利歐 波維尼
史考特 寇尼格
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美商宏觀基因股份有限公司
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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TW105123965A 2015-07-30 2016-07-28 Ｐｄ-１結合分子和其使用方法 TWI691509B (zh)

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Application Number Priority Date Filing Date Title
US201562198867P 2015-07-30 2015-07-30
US62/198,867 2015-07-30
US201562239559P 2015-10-09 2015-10-09
US62/239,559 2015-10-09
US201562255140P 2015-11-13 2015-11-13
US62/255,140 2015-11-13
US201662322974P 2016-04-15 2016-04-15
US62/322,974 2016-04-15

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TW201710292A TW201710292A (zh) 2017-03-16
TWI691509B true TWI691509B (zh) 2020-04-21

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TW113102094A TWI886756B (zh) 2015-07-30 2016-07-28 Pd-1結合分子和其使用方法
TW111110951A TWI833183B (zh) 2015-07-30 2016-07-28 Pd-1結合分子和其使用方法
TW114117234A TW202535469A (zh) 2015-07-30 2016-07-28 Pd-1結合分子和其使用方法
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TW114117234A TW202535469A (zh) 2015-07-30 2016-07-28 Pd-1結合分子和其使用方法
TW109107547A TWI762879B (zh) 2015-07-30 2016-07-28 Pd-1結合分子和其使用方法

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KR102269032B1 (ko) 2013-04-19 2021-06-24 인사이트 홀딩스 코포레이션 Fgfr 저해제로서 이환식 헤테로사이클
EP3954713A3 (en) 2014-03-28 2022-03-30 Xencor, Inc. Bispecific antibodies that bind to cd38 and cd3
NZ726520A (en) * 2014-05-29 2018-12-21 Macrogenics Inc Tri-specific binding molecules that specifically bind to multiple cancer antigens and methods of use thereof
TWI693232B (zh) * 2014-06-26 2020-05-11 美商宏觀基因股份有限公司 與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
CN116333153A (zh) 2014-11-26 2023-06-27 森科股份有限公司 结合cd3和肿瘤抗原的异二聚体抗体
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WO2016105450A2 (en) 2014-12-22 2016-06-30 Xencor, Inc. Trispecific antibodies
ES2895769T3 (es) 2015-02-20 2022-02-22 Incyte Corp Heterociclos bicíclicos como inhibidores de FGFR
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
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