SI2404919T1 - Heterocikliäśna spojina uporabna kot modulator za prenaĺ alce z atp-vezavno kaseto - Google Patents

Heterocikliäśna spojina uporabna kot modulator za prenaĺ alce z atp-vezavno kaseto

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Publication number
SI2404919T1
SI2404919T1 SI200631695T SI200631695T SI2404919T1 SI 2404919 T1 SI2404919 T1 SI 2404919T1 SI 200631695 T SI200631695 T SI 200631695T SI 200631695 T SI200631695 T SI 200631695T SI 2404919 T1 SI2404919 T1 SI 2404919T1
Authority
SI
Slovenia
Prior art keywords
atp
modulator
heterocyclic compound
compound useful
binding cassette
Prior art date
Application number
SI200631695T
Other languages
English (en)
Inventor
Ruah Sara Hadidda
Matthew Hamilton
Mark Miller
Peter D. J. Grootenhuis
Brian Bear
Jason Mccarthy
Jinglan Zhou
Original Assignee
Vertex Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37766297&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2404919(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of SI2404919T1 publication Critical patent/SI2404919T1/sl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4712—Cystic fibrosis
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US20080019915A1 (en) 2008-01-24
US20100210638A1 (en) 2010-08-19
SI1945632T1 (sl) 2014-03-31
DK2404919T3 (da) 2013-11-04
CN101356170A (zh) 2009-01-28
CY2016012I2 (el) 2016-10-05
NL300812I2 (sl) 2016-09-26
JP2012233011A (ja) 2012-11-29
JP5317184B2 (ja) 2013-10-16
PT2395002E (pt) 2014-09-16
PL1945632T3 (pl) 2014-03-31
EP3208272A1 (en) 2017-08-23
US20190322650A1 (en) 2019-10-24
US9216969B2 (en) 2015-12-22
LT2774925T (lt) 2017-04-10
HUE032640T2 (en) 2017-10-30
EP3208272B1 (en) 2020-01-08
SI2774925T1 (sl) 2017-04-26
RU2008122929A (ru) 2009-12-20
JP2014139243A (ja) 2014-07-31
EP2404919A1 (en) 2012-01-11
JP2009514962A (ja) 2009-04-09
IL191141A0 (en) 2008-12-29
US20170107205A1 (en) 2017-04-20
PL2395002T3 (pl) 2015-04-30
JP2015134835A (ja) 2015-07-27
US20210024505A1 (en) 2021-01-28
US20080306062A1 (en) 2008-12-11
EP2404919B1 (en) 2013-08-21
EP2774925B1 (en) 2016-12-28
US20130245011A1 (en) 2013-09-19
KR20080066086A (ko) 2008-07-15
ES2619608T3 (es) 2017-06-26
NZ567892A (en) 2010-12-24
EP2774925A1 (en) 2014-09-10
PT2404919E (pt) 2013-10-22
DK1945632T3 (da) 2013-12-16
US20100087435A1 (en) 2010-04-08
US8461156B2 (en) 2013-06-11

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