AU2001249417A1 - Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives - Google Patents

Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives

Info

Publication number
AU2001249417A1
AU2001249417A1 AU2001249417A AU4941701A AU2001249417A1 AU 2001249417 A1 AU2001249417 A1 AU 2001249417A1 AU 2001249417 A AU2001249417 A AU 2001249417A AU 4941701 A AU4941701 A AU 4941701A AU 2001249417 A1 AU2001249417 A1 AU 2001249417A1
Authority
AU
Australia
Prior art keywords
imidazoyl
chiral
intermediates
synthesis
cyclopropyl derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001249417A
Inventor
Syed M. Ali
Hans Joergen Kjaersgaard
Jim Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gliatech Inc
Original Assignee
Gliatech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gliatech Inc filed Critical Gliatech Inc
Publication of AU2001249417A1 publication Critical patent/AU2001249417A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
AU2001249417A 2000-04-26 2001-03-26 Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives Abandoned AU2001249417A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19972200P 2000-04-26 2000-04-26
US60199722 2000-04-26
PCT/US2001/009445 WO2001081317A1 (en) 2000-04-26 2001-03-26 Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives

Publications (1)

Publication Number Publication Date
AU2001249417A1 true AU2001249417A1 (en) 2001-11-07

Family

ID=22738752

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001249417A Abandoned AU2001249417A1 (en) 2000-04-26 2001-03-26 Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives

Country Status (3)

Country Link
US (1) US20010047100A1 (en)
AU (1) AU2001249417A1 (en)
WO (1) WO2001081317A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2404919B1 (en) 2005-11-08 2013-08-21 Vertex Pharmaceuticals Incorporated Heterocyclic compound useful as a modulator of ATP-binding cassette transporters.
US7671221B2 (en) 2005-12-28 2010-03-02 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
US7754739B2 (en) 2007-05-09 2010-07-13 Vertex Pharmaceuticals Incorporated Modulators of CFTR
EP1942104A1 (en) 2006-12-20 2008-07-09 sanofi-aventis Heteroarylcyclopropanecarboxamides and their use as pharmaceuticals
CN101687842B (en) 2007-05-09 2013-03-06 沃泰克斯药物股份有限公司 Modulators of CFTR
LT2639224T (en) 2007-12-07 2016-10-25 Vertex Pharmaceuticals Incorporated Process for producing cycloalkylcarboxiamido-pyridine benzoic acids
MX367154B (en) 2007-12-07 2019-08-07 Vertex Pharma Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3] dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid.
CA2931134C (en) 2008-02-28 2019-07-30 Vertex Pharmaceuticals Incorporated Heteroaryl derivatives as cftr modulators
JP2013523833A (en) 2010-04-07 2013-06-17 バーテックス ファーマシューティカルズ インコーポレイテッド 3- (6- (1- (2,2-difluorobenzo [D] [1,3] dioxol-5-yl) cyclopropanecarboxamido) -3-methylpyridin-2-yl) benzoic acid pharmaceutical composition and Its administration
PL3068392T3 (en) 2013-11-12 2021-07-19 Vertex Pharmaceuticals Incorporated Process of preparing pharmaceutical compositions for the treatment of cftr mediated diseases
MX2017006443A (en) 2014-11-18 2017-09-11 Vertex Pharma Process of conducting high throughput testing high performance liquid chromatography.
CR20200054A (en) 2017-08-09 2020-03-21 Denali Therapeutics Inc Compounds, compositions and methods
MA54953A (en) * 2019-02-13 2021-12-22 Denali Therapeutics Inc COMPOUNDS, COMPOSITIONS AND METHODS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686084B1 (en) * 1992-01-10 1995-12-22 Bioprojet Soc Civ NEW IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATIONS.

Also Published As

Publication number Publication date
WO2001081317A1 (en) 2001-11-01
US20010047100A1 (en) 2001-11-29

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