|
WO2001014424A2
(en)
*
|
1999-08-24 |
2001-03-01 |
Medarex, Inc. |
Human ctla-4 antibodies and their uses
|
|
US7605238B2
(en)
*
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
HUP0300423A3
(en)
|
2000-02-10 |
2008-07-28 |
Abbott Lab |
Antibodies that bind human interleukin-18 and methods of making and using
|
|
WO2002088170A2
(en)
|
2001-04-26 |
2002-11-07 |
Biogen, Inc. |
Cripto blocking antibodies and uses thereof
|
|
US7981420B2
(en)
|
2000-12-22 |
2011-07-19 |
Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. |
Therapeutic use of antibodies directed against repulsive guidance molecule (RGM)
|
|
MX337162B
(es)
|
2001-01-05 |
2016-02-15 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina.
|
|
WO2002092017A2
(en)
|
2001-05-16 |
2002-11-21 |
Albert Einstein College Of Medicine Of Yeshiva University |
Human antipneumococcal antibodies from non-human animals
|
|
IL149701A0
(en)
*
|
2001-05-23 |
2002-11-10 |
Pfizer Prod Inc |
Use of anti-ctla-4 antibodies
|
|
MEP32608A
(hr)
*
|
2001-06-26 |
2011-02-10 |
Amgen Fremont Inc |
Antitijela za opgl
|
|
AU2006228095B2
(en)
*
|
2001-10-11 |
2010-11-04 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
US7521053B2
(en)
*
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
MXPA04009418A
(es)
|
2002-03-29 |
2005-06-08 |
Schering Corp |
Anticuerpos monoclonales humanos par interleucina-5, y metodos y composiciones que comprenden los mismos.
|
|
ES2384168T3
(es)
*
|
2002-04-12 |
2012-07-02 |
Medarex, Inc. |
Procedimientos de tratamiento usando anticuerpos CTLA-4
|
|
AU2003260871A1
(en)
*
|
2002-09-30 |
2004-04-19 |
Pfizer Products Inc. |
Hybridomas producing high levels of human sequence antibody
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US7465446B2
(en)
|
2003-05-30 |
2008-12-16 |
Medarex, Inc. |
Surrogate therapeutic endpoint for anti-CTLA4-based immunotherapy of disease
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
WO2005019270A2
(en)
*
|
2003-08-14 |
2005-03-03 |
Dyax Corp. |
Endotheliase-2 ligands
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
US20050100965A1
(en)
|
2003-11-12 |
2005-05-12 |
Tariq Ghayur |
IL-18 binding proteins
|
|
SV2006001990A
(es)
|
2004-01-09 |
2006-01-30 |
Pfizer |
Anticuerpos contra madcam
|
|
WO2005092380A2
(en)
*
|
2004-03-26 |
2005-10-06 |
Pfizer Products Inc |
Uses of anti-ctla-4 antibodies
|
|
US7494779B2
(en)
|
2004-06-14 |
2009-02-24 |
Li-Te Chin |
Method for producing human antibodies to human CD152 with properties of agonist, antagonist, or inverse agonist
|
|
AU2005259221B2
(en)
|
2004-07-01 |
2011-02-10 |
Innate Pharma |
Antibodies binding to receptors KIR2DL1, -2, 3 but not KIR2DS4 and their therapeutic use
|
|
CA2573821A1
(en)
|
2004-07-16 |
2006-01-26 |
Pfizer Products Inc. |
Combination treatment for non-hematologic malignancies using an anti-igf-1r antibody
|
|
US7892827B2
(en)
|
2004-11-26 |
2011-02-22 |
Pieris Ag |
Compound with affinity for the cytotoxic T lymphocyte-associated antigen (CTLA-4)
|
|
CA2600608A1
(en)
|
2005-03-08 |
2006-09-14 |
Pharmacia & Upjohn Company Llc |
Composition comprising human igg2 antibody and chelating agent
|
|
AU2014240252B2
(en)
*
|
2005-03-08 |
2016-10-06 |
Pfizer Products Inc |
Anti-CTLA-4 Antibody Compositions
|
|
AU2012200203B2
(en)
*
|
2005-03-08 |
2014-07-03 |
Pfizer Products Inc. |
Anti-CTLA-4 Antibody Compositions
|
|
JP2006265155A
(ja)
*
|
2005-03-23 |
2006-10-05 |
Link Genomics Kk |
癌の免疫療法
|
|
RU2007134867A
(ru)
*
|
2005-03-23 |
2009-04-27 |
Пфайзер Продактс Инк. (Us) |
Терапия рака предстательной железы ctla4-антителами и гормональной терапией
|
|
PT2343320T
(pt)
|
2005-03-25 |
2018-01-23 |
Gitr Inc |
Anticorpos anti-gitr e as suas utilizações
|
|
EA201100642A1
(ru)
|
2005-04-25 |
2011-12-30 |
Пфайзер Инк. |
Антитела к миостатину
|
|
EP2444419A1
(en)
|
2005-04-26 |
2012-04-25 |
Pfizer Inc. |
P-Cadherin antibodies
|
|
WO2006117910A1
(ja)
|
2005-04-28 |
2006-11-09 |
Mochida Pharmaceutical Co., Ltd. |
抗血小板膜糖蛋白質ⅵモノクローナル抗体
|
|
JP5224707B2
(ja)
*
|
2005-04-28 |
2013-07-03 |
持田製薬株式会社 |
抗血小板膜糖蛋白質ｖｉモノクローナル抗体
|
|
EP2418278A3
(en)
|
2005-05-09 |
2012-07-04 |
Ono Pharmaceutical Co., Ltd. |
Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics
|
|
AU2006254902B8
(en)
|
2005-06-08 |
2012-08-16 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (PD-1) pathway
|
|
AU2006269555A1
(en)
*
|
2005-07-07 |
2007-01-18 |
Coley Pharmaceutical Group, Inc. |
Anti-CTLA-4 antibody and CpG-motif-containing synthetic oligodeoxynucleotide combination therapy for cancer treatment
|
|
CN100443503C
(zh)
*
|
2005-07-18 |
2008-12-17 |
四川大学华西医院 |
人源化ctla-4单链抗体与人穿孔素通道形成肽p34的重组免疫毒素
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
KR20130108481A
(ko)
|
2005-08-19 |
2013-10-02 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
EP2500359A3
(en)
|
2005-08-19 |
2012-10-17 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
DOP2006000195A
(es)
|
2005-09-07 |
2017-08-15 |
Amgen Fremont Inc |
Anticuerpos monoclonales humanos para la quinasa-1 tipo receptor de activina
|
|
US7700567B2
(en)
|
2005-09-29 |
2010-04-20 |
Supergen, Inc. |
Oligonucleotide analogues incorporating 5-aza-cytosine therein
|
|
EP1928905B1
(de)
|
2005-09-30 |
2015-04-15 |
AbbVie Deutschland GmbH & Co KG |
Bindungsdomänen von proteinen der repulsive guidance molecule (rgm) proteinfamilie und funktionale fragmente davon sowie deren verwendung
|
|
CN101300024A
(zh)
|
2005-11-08 |
2008-11-05 |
米德列斯公司 |
对于与免疫刺激性治疗抗体治疗有关的小肠结肠炎的TNF-α阻断剂治疗
|
|
KR101667623B1
(ko)
|
2005-11-30 |
2016-10-19 |
애브비 인코포레이티드 |
아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도
|
|
DK1954718T3
(en)
|
2005-11-30 |
2014-12-15 |
Abbvie Inc |
Anti-A-globulomer antibodies antigenbindingsgrupper thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods for producing said antibodies,
|
|
AU2006321593B2
(en)
|
2005-12-07 |
2012-10-04 |
E. R. Squibb & Sons, L.L.C. |
CTLA-4 antibody dosage escalation regimens
|
|
EP2889309B1
(en)
|
2006-03-03 |
2017-12-27 |
Ono Pharmaceutical Co., Ltd. |
Multimer of extracellular domain of pd-1 or pd-l1
|
|
US9868961B2
(en)
|
2006-03-30 |
2018-01-16 |
The Regents Of The University Of California |
Methods and compositions for localized secretion of anti-CTLA-4 antibodies
|
|
US7919079B2
(en)
*
|
2006-03-31 |
2011-04-05 |
Biosante Pharmaceuticals, Inc. |
Cancer immunotherapy compositions and methods of use
|
|
AU2007234733A1
(en)
|
2006-04-07 |
2007-10-18 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Antibody compositions and methods for treatment of neoplastic disease
|
|
PL2511301T3
(pl)
|
2006-08-04 |
2018-05-30 |
Medimmune Limited |
Ludzkie przeciwciała do ErbB2
|
|
ES2817756T3
(es)
|
2006-09-08 |
2021-04-08 |
Abbvie Bahamas Ltd |
Proteínas de unión a interleuquina-13
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
US8895004B2
(en)
|
2007-02-27 |
2014-11-25 |
AbbVie Deutschland GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
EP2134855A4
(en)
|
2007-03-12 |
2011-01-05 |
Dana Farber Cancer Inst Inc |
USES OF FANCI AND FANCI MODULATING AGENTS IN PROGNOSIS, DIAGNOSIS AND CANCER THERAPY
|
|
US7867494B2
(en)
|
2007-04-02 |
2011-01-11 |
Amgen Fremont Inc. |
Anti-IgE antibodies
|
|
US8591886B2
(en)
|
2007-07-12 |
2013-11-26 |
Gitr, Inc. |
Combination therapies employing GITR binding molecules
|
|
NZ584848A
(en)
|
2007-09-28 |
2012-09-28 |
Intrexon Corp |
Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
|
|
RU2506275C2
(ru)
|
2007-11-01 |
2014-02-10 |
Астеллас Фарма Инк. |
Иммуносупрессорные полипептиды и нуклеиновые кислоты
|
|
CA2949772A1
(en)
|
2007-12-14 |
2009-06-25 |
Pfizer Inc. |
Binding molecules to the human ox40 receptor
|
|
KR20100100949A
(ko)
|
2008-01-08 |
2010-09-15 |
브리스톨-마이어스 스큅 컴퍼니 |
증식성 질환의 치료를 위한 튜불린 조정제와 항-ｃｔｌａ４ 항체의 조합물
|
|
WO2009100140A1
(en)
*
|
2008-02-04 |
2009-08-13 |
Medarex, Inc. |
Anti-clta-4 antibodies with reduced blocking of binding of ctla-4 to b7 and uses thereof
|
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
KR20110014607A
(ko)
|
2008-04-29 |
2011-02-11 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
MY159667A
(en)
|
2008-05-09 |
2017-01-13 |
Abbvie Inc |
Antibodies to receptor of advanced glycation end products (rage) and uses thereof
|
|
JP2011523853A
(ja)
|
2008-06-03 |
2011-08-25 |
アボット・ラボラトリーズ |
二重可変ドメイン免疫グロブリン及びその使用
|
|
US9109026B2
(en)
|
2008-06-03 |
2015-08-18 |
Abbvie, Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
EP2810654A1
(en)
|
2008-07-08 |
2014-12-10 |
AbbVie Inc. |
Prostaglandin E2 binding proteins and uses thereof
|
|
CA2729949A1
(en)
|
2008-07-08 |
2010-01-14 |
Abbott Laboratories |
Prostaglandin e2 dual variable domain immunoglobulins and uses thereof
|
|
WO2010014784A2
(en)
|
2008-08-01 |
2010-02-04 |
Bristol-Myers Squibb Company |
Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
ES2658117T3
(es)
|
2008-08-18 |
2018-03-08 |
Pfizer Inc. |
Anticuerpos anti-CCR2
|
|
KR101012267B1
(ko)
*
|
2008-08-29 |
2011-02-08 |
주식회사 세이프로드 |
파손이 방지되는 차선규제봉 및 차선규제봉 시공방법
|
|
WO2010042433A1
(en)
|
2008-10-06 |
2010-04-15 |
Bristol-Myers Squibb Company |
Combination of cd137 antibody and ctla-4 antibody for the treatment of proliferative diseases
|
|
WO2010083456A1
(en)
|
2009-01-15 |
2010-07-22 |
Imdaptive Inc. |
Adaptive immunity profiling and methods for generation of monoclonal antibodies
|
|
MX2011009362A
(es)
|
2009-03-05 |
2011-09-26 |
Abbott Lab |
Proteinas de union a il-17.
|
|
US8283162B2
(en)
|
2009-03-10 |
2012-10-09 |
Abbott Laboratories |
Antibodies relating to PIVKAII and uses thereof
|
|
KR101733255B1
(ko)
|
2009-07-20 |
2017-05-08 |
브리스톨-마이어스 스큅 컴퍼니 |
증식성 질환의 상승작용적 치료를 위한 항ｃｔｌａ４ 항체와 다양한 치료 요법의 조합
|
|
CA2952742A1
(en)
|
2009-08-29 |
2011-03-03 |
Abbvie Inc. |
Therapeutic dll4 binding proteins
|
|
CN102612524A
(zh)
|
2009-09-01 |
2012-07-25 |
雅培制药有限公司 |
双重可变结构域免疫球蛋白及其用途
|
|
EP2488553B1
(en)
|
2009-10-12 |
2015-06-17 |
Pfizer Inc. |
Cancer treatment
|
|
UY32948A
(es)
|
2009-10-15 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
TW201121568A
(en)
|
2009-10-31 |
2011-07-01 |
Abbott Lab |
Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
|
|
WO2011070045A1
(en)
|
2009-12-08 |
2011-06-16 |
Abbott Gmbh & Co. Kg |
Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
|
|
NZ602734A
(en)
|
2010-03-02 |
2014-10-31 |
Abbvie Inc |
Therapeutic dll4 binding proteins
|
|
WO2011130377A2
(en)
|
2010-04-15 |
2011-10-20 |
Abbott Laboratories |
Amyloid-beta binding proteins
|
|
AU2011252883B2
(en)
|
2010-05-14 |
2015-09-10 |
Abbvie Inc. |
IL-1 binding proteins
|
|
EP2571577A1
(en)
|
2010-05-17 |
2013-03-27 |
Bristol-Myers Squibb Company |
Improved immunotherapeutic dosing regimens and combinations thereof
|
|
WO2012006500A2
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
US9120862B2
(en)
|
2010-07-26 |
2015-09-01 |
Abbott Laboratories |
Antibodies relating to PIVKA-II and uses thereof
|
|
PE20131412A1
(es)
|
2010-08-03 |
2014-01-19 |
Abbvie Inc |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
CN105348387B
(zh)
|
2010-08-14 |
2020-08-25 |
Abbvie 公司 |
β淀粉样蛋白结合蛋白
|
|
DK3333188T3
(da)
|
2010-08-19 |
2022-03-07 |
Zoetis Belgium S A |
Anti-NGF-antistoffer og deres anvendelse
|
|
US9046513B2
(en)
|
2010-08-26 |
2015-06-02 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
WO2012072806A1
(en)
*
|
2010-12-02 |
2012-06-07 |
Pieris Ag |
Muteins of human lipocalin 2 with affinity for ctla-4
|
|
MX348152B
(es)
|
2010-12-14 |
2017-06-02 |
Nat Univ Singapore |
Anticuerpo monoclonal humano con especificidad para el virus del dengue serotipo 1 proteina e y sus usos.
|
|
KR20130133247A
(ko)
|
2010-12-21 |
2013-12-06 |
애브비 인코포레이티드 |
Ｉｌ-1-알파 및 -베타 이특이적 이원 가변 도메인 면역글로불린 및 이의 용도
|
|
US20120275996A1
(en)
|
2010-12-21 |
2012-11-01 |
Abbott Laboratories |
IL-1 Binding Proteins
|
|
GB201103955D0
(en)
|
2011-03-09 |
2011-04-20 |
Antitope Ltd |
Antibodies
|
|
US9150644B2
(en)
|
2011-04-12 |
2015-10-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
|
|
RU2719132C2
(ru)
|
2011-06-30 |
2020-04-17 |
Чугаи Сейяку Кабусики Кайся |
Гетеродимеризованный полипептид
|
|
CN103857411A
(zh)
|
2011-07-13 |
2014-06-11 |
阿布维公司 |
使用抗il-13抗体治疗哮喘的方法和组合物
|
|
WO2013013029A1
(en)
|
2011-07-19 |
2013-01-24 |
The Board Of Trustees Of The University Of Illinois |
Anti-clta4, anti-glut2 protein for the treatment of type 1 diabetes
|
|
EP2750768B1
(en)
|
2011-08-30 |
2018-10-03 |
Astex Pharmaceuticals, Inc. |
Decitabine derivative formulations
|
|
WO2013063095A1
(en)
|
2011-10-24 |
2013-05-02 |
Abbvie Inc. |
Immunobinders directed against sclerostin
|
|
PH12014500866A1
(en)
|
2011-10-24 |
2014-05-26 |
Abbvie Inc |
Immunobinders directed against tnf
|
|
RU2014114015A
(ru)
|
2011-11-08 |
2015-12-20 |
Пфайзер Инк. |
Способы лечения воспалительных расстройств с использованием антител против m-csf
|
|
CN104136462B
(zh)
|
2011-12-14 |
2017-06-09 |
艾伯维德国有限责任两合公司 |
用于诊断和治疗铁相关病症的组合物和方法
|
|
CN107459576A
(zh)
|
2011-12-14 |
2017-12-12 |
艾伯维德国有限责任两合公司 |
用于诊断和治疗铁相关病症的组合物和方法
|
|
AR089529A1
(es)
|
2011-12-30 |
2014-08-27 |
Abbvie Inc |
Proteinas de union especificas duales dirigidas contra il-13 y/o il-17
|
|
EP2807192B1
(en)
|
2012-01-27 |
2018-04-18 |
Abbvie Deutschland GmbH & Co. KG |
Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
|
|
WO2013138702A2
(en)
|
2012-03-15 |
2013-09-19 |
Bristol-Myers Squibb Company |
Methods for predicting gastrointestinal immune-related adverse events (gi-irae) in patients treated with modulation of the co-stimulatory pathway
|
|
US20150079100A1
(en)
|
2012-03-23 |
2015-03-19 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla-4 antibodies
|
|
WO2013155447A1
(en)
|
2012-04-13 |
2013-10-17 |
Children's Medical Center Corporation |
Tiki inhibitors
|
|
CN105457021A
(zh)
|
2012-05-04 |
2016-04-06 |
辉瑞公司 |
前列腺相关抗原及基于疫苗的免疫治疗疗法
|
|
WO2013169971A1
(en)
|
2012-05-10 |
2013-11-14 |
Bristol-Myers Squibb Company |
Anti-tumor antibodies as predictive or prognostic biomarkers of efficacy and survival in ipilimumab-treated patients
|
|
EP2850102A1
(en)
|
2012-05-15 |
2015-03-25 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
|
|
US9617334B2
(en)
|
2012-06-06 |
2017-04-11 |
Zoetis Services Llc |
Caninized anti-NGF antibodies and methods thereof
|
|
AR091649A1
(es)
|
2012-07-02 |
2015-02-18 |
Bristol Myers Squibb Co |
Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
|
|
AR091755A1
(es)
|
2012-07-12 |
2015-02-25 |
Abbvie Inc |
Proteinas de union a il-1
|
|
DK2887959T3
(en)
*
|
2012-08-23 |
2019-02-18 |
Agensys Inc |
ANTIBODY-PHARMACEUTICAL CONJUGATES (ADC) BINDING TO 158P1D7 PROTEINS
|
|
JP6109952B2
(ja)
|
2012-11-01 |
2017-04-05 |
アッヴィ・インコーポレイテッド |
抗ｖｅｇｆ／ｄｌｌ４二重可変ドメイン免疫グロブリンおよびこれらの使用
|
|
WO2014100542A1
(en)
|
2012-12-21 |
2014-06-26 |
Abbvie, Inc. |
High-throughput antibody humanization
|
|
SG10201707135RA
(en)
|
2013-03-01 |
2017-10-30 |
Astex Pharmaceuticals Inc |
Drug combinations
|
|
BR112015023355A8
(pt)
|
2013-03-14 |
2018-01-30 |
Abbott Lab |
antígenos recombinantes ns3 de hcv e mutantes dos mesmos para detecção de anticorpos aprimorada.
|
|
JP6505076B2
(ja)
|
2013-03-14 |
2019-04-24 |
アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ |
Ｈｃｖ抗原−抗体組み合わせアッセイおよびこれに使用するための方法および組成物
|
|
RU2015142815A
(ru)
|
2013-03-14 |
2017-04-12 |
Паркаш ГИЛЛ |
Лечение рака с использованием антител, связывающихся с поверхностным grp78
|
|
JP6739329B2
(ja)
|
2013-03-14 |
2020-08-12 |
アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ |
Ｈｃｖコア脂質結合ドメインモノクローナル抗体
|
|
CA2904448A1
(en)
|
2013-03-15 |
2014-09-18 |
Tariq Ghayur |
Dual specific binding proteins directed against il-1.beta. and/or il-17
|
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
|
JP6581572B2
(ja)
|
2013-06-07 |
2019-09-25 |
デューク ユニバーシティ |
補体因子ｈ阻害薬
|
|
SMT201900684T1
(it)
|
2013-08-08 |
2020-03-13 |
Cytune Pharma |
Composizione farmaceutica combinata
|
|
SI3444271T1
(sl)
|
2013-08-08 |
2022-03-31 |
Cytune Pharma |
Modulokini na osnovi IL-15 in IL-15Ralfa sushi domene
|
|
EP3508502B1
(en)
|
2013-09-20 |
2023-04-26 |
Bristol-Myers Squibb Company |
Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors
|
|
TR201903074T4
(tr)
|
2013-11-01 |
2019-03-21 |
Pfizer |
Prostat ile bağlantılı antijenlerin ekspresyonuna yönelik vektörler.
|
|
MX2016005925A
(es)
|
2013-11-05 |
2016-11-28 |
Cognate Bioservices Inc |
Combinaciones de inhibidores de punto de regulacion y terapeuticos para tratar el cancer.
|
|
EP3066127A1
(en)
|
2013-11-06 |
2016-09-14 |
Bristol-Myers Squibb Company |
Immunotherapeutic dosing regimens and combinations thereof
|
|
AU2015205530B8
(en)
|
2014-01-13 |
2019-09-19 |
Pieris Pharmaceuticals Gmbh |
Multi-specific polypeptide useful for localized tumor immunomodulation
|
|
IL249092B
(en)
|
2014-05-28 |
2022-07-01 |
Agenus Inc |
Anti-gitr antibodies and methods of use thereof
|
|
CN106459203B
(zh)
|
2014-06-06 |
2021-08-03 |
百时美施贵宝公司 |
抗糖皮质激素诱导肿瘤坏死因子受体(gitr)的抗体及其用途
|
|
CN105296433B
(zh)
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
|
PL3186281T3
(pl)
|
2014-08-28 |
2019-10-31 |
Halozyme Inc |
Terapia skojarzona enzymem rozkładającym hialuronian i inhibitorem punktu kontrolnego odpowiedzi immunologicznej
|
|
CN106470697B
(zh)
|
2014-09-16 |
2019-10-25 |
兴盟生物医药(苏州)有限公司 |
抗egfr抗体以及其用途
|
|
US20160101128A1
(en)
|
2014-10-10 |
2016-04-14 |
Idera Pharmaceuticals, Inc. |
Treatment of cancer using tlr9 agonist with checkpoint inhibitors
|
|
PL3207130T3
(pl)
|
2014-10-14 |
2020-02-28 |
Halozyme, Inc. |
Kompozycje deaminazy adenozyny 2 (ada2), jej warianty i sposoby ich zastosowania
|
|
CN107074976B
(zh)
*
|
2014-11-04 |
2020-10-09 |
北京韩美药品有限公司 |
同时阻断b7/cd28和il6/il6r/gp130信号通路的重组融合蛋白
|
|
WO2016074580A1
(zh)
*
|
2014-11-14 |
2016-05-19 |
中国科学院上海生命科学研究院 |
一种提高cd4阳性t淋巴细胞存活率和活性的试剂及其应用
|
|
US10653791B2
(en)
|
2014-11-21 |
2020-05-19 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
WO2016081748A2
(en)
|
2014-11-21 |
2016-05-26 |
Bristol-Myers Squibb Company |
Antibodies against cd73 and uses thereof
|
|
AU2015358462A1
(en)
|
2014-12-04 |
2017-07-27 |
Bristol-Myers Squibb Company |
Combination of anti-CS1 and anti-PD1 antibodies to treat cancer (myeloma)
|
|
CN104387453A
(zh)
*
|
2014-12-08 |
2015-03-04 |
深圳市同康生物医药有限公司 |
树突状细胞靶向肽及编码基因及应用
|
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
|
TWI708786B
(zh)
|
2014-12-23 |
2020-11-01 |
美商必治妥美雅史谷比公司 |
針對ｔｉｇｉｔ之抗體
|
|
PL3240801T3
(pl)
|
2014-12-31 |
2021-06-14 |
Checkmate Pharmaceuticals, Inc. |
Skojarzona immunoterapia nowotworów
|
|
US10983128B2
(en)
|
2015-02-05 |
2021-04-20 |
Bristol-Myers Squibb Company |
CXCL11 and SMICA as predictive biomarkers for efficacy of anti-CTLA4 immunotherapy
|
|
AU2016219170B2
(en)
*
|
2015-02-13 |
2021-09-09 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind CTLA4
|
|
US20180133327A1
(en)
|
2015-03-16 |
2018-05-17 |
Amal Therapeutics Sa |
Cell Penetrating Peptides and Complexes Comprising the Same
|
|
US10376535B2
(en)
|
2015-03-26 |
2019-08-13 |
University Of Rochester |
Therapy for malignant disease
|
|
BR112017020404A2
(pt)
|
2015-04-07 |
2018-07-10 |
Cytlimic Inc. |
medicamento
|
|
SI3291679T1
(sl)
|
2015-05-06 |
2022-04-29 |
Snipr Technologies Limited |
Predrugačenje mikrobnih populacij in spreminjanje mikrobiote
|
|
CN107921126A
(zh)
|
2015-05-22 |
2018-04-17 |
转化药物开发有限责任公司 |
苯甲酰胺和活性化合物的组合物及其使用方法
|
|
WO2016196314A1
(en)
|
2015-05-29 |
2016-12-08 |
Abbvie Inc. |
Anti-cd40 antibodies and uses thereof
|
|
PE20180926A1
(es)
|
2015-05-29 |
2018-06-08 |
Bristol Myers Squibb Co |
Anticuerpos contra el miembro 4 de la superfamilia del receptor del factor de necrosis tumoral (ox40) y sus usos
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
|
|
UY36757A
(es)
|
2015-06-29 |
2016-12-30 |
Bristol Myers Squibb Company Una Corporación Del Estado De Delaware |
Anticuerpos monoclonales murinos contra cd40 con actividad agonista mejorada
|
|
MX391581B
(es)
|
2015-06-29 |
2025-03-04 |
Bristol Myers Squibb Co |
Regimenes de dosificacion inmunoterapeutica que comprenden pomalidomida y un anticuerpo anti-cs1 para el tratamiento de cancer.
|
|
EP3316685A4
(en)
|
2015-07-02 |
2019-03-13 |
Otsuka Pharmaceutical Co., Ltd. |
Lyophilized Pharmaceutical Compositions
|
|
WO2017011831A1
(en)
|
2015-07-16 |
2017-01-19 |
Bioxcel Corporation |
A novel approach for treatment of cancer using immunomodulation
|
|
CN107921087A
(zh)
|
2015-07-16 |
2018-04-17 |
百欧肯治疗有限公司 |
治疗癌症的组合物及方法
|
|
EP3331917A1
(en)
|
2015-08-04 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
|
WO2017025871A1
(en)
|
2015-08-07 |
2017-02-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
|
AU2016319133B2
(en)
|
2015-09-11 |
2023-06-08 |
Mark C. Glassy |
Enhanced delivery of drugs to the brain
|
|
ES2892972T3
(es)
|
2015-11-02 |
2022-02-07 |
Univ Texas |
Métodos de activación de CD40 y bloqueo de punto de control inmunitario
|
|
WO2017079215A1
(en)
|
2015-11-03 |
2017-05-11 |
Glycomimetics, Inc. |
Methods and compositions for the production of monoclonal antibodies, hematopoietic stem cells, and methods of using the same
|
|
EP3371221A2
(en)
|
2015-11-07 |
2018-09-12 |
MultiVir Inc. |
Methods and compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer
|
|
EA201891121A1
(ru)
|
2015-11-19 |
2018-12-28 |
Бристол-Майерс Сквибб Компани |
Антитела к глюкокортикоид-индуцированному рецептору фактора некроза опухоли (gitr) и их применения
|
|
MA44312A
(fr)
|
2015-12-02 |
2018-10-10 |
Agenus Inc |
Anticorps et leurs méthodes d'utilisation
|
|
HK1255039A1
(zh)
|
2015-12-14 |
2019-08-02 |
Macrogenics, Inc. |
对pd-1和ctla-4具有免疫反应性的双特异性分子及其使用方法
|
|
MA43587A
(fr)
|
2016-01-10 |
2018-11-14 |
Modernatx Inc |
Arnm thérapeutiques codant pour des anticorps anti-ctla-4
|
|
WO2017152085A1
(en)
|
2016-03-04 |
2017-09-08 |
Bristol-Myers Squibb Company |
Combination therapy with anti-cd73 antibodies
|
|
WO2017160599A1
(en)
|
2016-03-14 |
2017-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Use of cd300b antagonists to treat sepsis and septic shock
|
|
BR112018068461A2
(pt)
|
2016-03-15 |
2019-01-22 |
Mersana Therapeutics Inc |
conjugado, composição farmacêutica, métodos para preparação de um conjugado e para alívio de um sintoma de um câncer.
|
|
JP7189021B2
(ja)
|
2016-03-16 |
2022-12-13 |
アマル セラピューティクス エスエー |
医療において使用するための、免疫チェックポイントモジュレータと、細胞透過性ペプチド、カーゴ、及びｔｌｒペプチドアゴニストを含む複合体との組合せ
|
|
WO2017173091A1
(en)
|
2016-03-30 |
2017-10-05 |
Musc Foundation For Research Development |
Methods for treatment and diagnosis of cancer by targeting glycoprotein a repetitions predominant (garp) and for providing effective immunotherapy alone or in combination
|
|
EP3436066A1
(en)
|
2016-04-01 |
2019-02-06 |
Checkmate Pharmaceuticals, Inc. |
Fc receptor-mediated drug delivery
|
|
CN116059351A
(zh)
|
2016-04-18 |
2023-05-05 |
塞德斯医疗公司 |
结合人cd40的激动性抗体及其用途
|
|
PL3449017T3
(pl)
|
2016-04-29 |
2022-06-27 |
Board Of Regents, The University Of Texas System |
Ukierunkowane pomiary aktywności transkrypcyjnej związanej z receptorami hormonów
|
|
WO2017192874A1
(en)
|
2016-05-04 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Albumin-binding immunomodulatory compositions and methods of use thereof
|
|
AU2017268399B2
(en)
|
2016-05-18 |
2023-01-12 |
Modernatx, Inc. |
mRNA combination therapy for the treatment of cancer
|
|
CA3026054A1
(en)
|
2016-05-30 |
2017-12-07 |
Geovax Inc. |
Compositions and methods for generating an immune response to hepatitis b virus
|
|
WO2017210335A1
(en)
|
2016-06-01 |
2017-12-07 |
Bristol-Myers Squibb Company |
Imaging methods using 18f-radiolabeled biologics
|
|
GB201609811D0
(en)
|
2016-06-05 |
2016-07-20 |
Snipr Technologies Ltd |
Methods, cells, systems, arrays, RNA and kits
|
|
WO2017220989A1
(en)
|
2016-06-20 |
2017-12-28 |
Kymab Limited |
Anti-pd-l1 and il-2 cytokines
|
|
MX2019000252A
(es)
|
2016-06-30 |
2019-10-09 |
Oncorus Inc |
Administracion viral oncolitica pseudotipada de polipeptidos terapeuticos.
|
|
TW202244061A
(zh)
|
2016-07-14 |
2022-11-16 |
美商必治妥美雅史谷比公司 |
針對tim3之抗體及其用途
|
|
NL2017270B1
(en)
*
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
|
WO2018025221A1
(en)
|
2016-08-04 |
2018-02-08 |
Glaxosmithkline Intellectual Property Development Limited |
Anti-icos and anti-pd-1 antibody combination therapy
|
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
|
ES2983085T3
(es)
|
2016-09-21 |
2024-10-21 |
Amal Therapeutics Sa |
Fusión que comprende un péptido de penetración celular, un multiepítopo y un agonista peptídico de TLR para el tratamiento de cáncer
|
|
KR102708641B1
(ko)
|
2016-09-27 |
2024-09-24 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
미생물유전체를 조정함으로써 면역 체크포인트 차단 요법을 증강시키는 방법
|
|
CA3036717A1
(en)
|
2016-10-03 |
2018-04-12 |
Abbott Laboratories |
Improved methods of assessing gfap status in patient samples
|
|
WO2018068182A1
(en)
*
|
2016-10-10 |
2018-04-19 |
Crown Bioscience (Taicang) Inc. |
Novel anti-ctla4 antibodies
|
|
TW201813664A
(zh)
|
2016-10-11 |
2018-04-16 |
賽多利克公司 |
醫藥
|
|
MX386249B
(es)
|
2016-10-12 |
2025-03-18 |
Univ Texas |
Terapia tusc2 para usarse en el tratamiento de cáncer.
|
|
CN110099925A
(zh)
|
2016-10-28 |
2019-08-06 |
百时美施贵宝公司 |
使用抗pd-1抗体治疗尿道上皮癌的方法
|
|
AU2017356860A1
(en)
|
2016-11-08 |
2019-05-16 |
Qilu Puget Sound Biotherapeutics Corporation |
Anti-PD1 and anti-CTLA4 antibodies
|
|
WO2018089628A1
(en)
|
2016-11-09 |
2018-05-17 |
Agenus Inc. |
Anti-ox40 antibodies, anti-gitr antibodies, and methods of use thereof
|
|
CA3043356A1
(en)
|
2016-11-09 |
2018-05-17 |
Musc Foundation For Research Development |
Cd38-nad+ regulated metabolic axis in anti-tumor immunotherapy
|
|
WO2018094225A1
(en)
|
2016-11-17 |
2018-05-24 |
Board Of Regents, The University Of Texas System |
Compounds with anti-tumor activity against cancer cells bearing egfr or her2 exon 20 mutations
|
|
AU2017363337B2
(en)
|
2016-11-23 |
2021-07-01 |
Translational Drug Development, Llc |
Benzamide and active compound compositions and methods of use
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
WO2018099539A1
(en)
|
2016-11-29 |
2018-06-07 |
Horst Lindhofer |
Combination of t-cell redirecting multifunctional antibodies with immune checkpoint modulators and uses thereof
|
|
BR112019011370A2
(pt)
|
2016-12-01 |
2019-10-15 |
Glaxosmithkline Ip Dev Ltd |
terapia de combinação
|
|
AU2017369994A1
(en)
|
2016-12-01 |
2019-06-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
|
KR20250040100A
(ko)
|
2016-12-12 |
2025-03-21 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 콘주게이트와 면역 체크 포인트 저해제의 조합
|
|
KR20190112263A
(ko)
|
2016-12-12 |
2019-10-04 |
멀티비르 인코포레이티드 |
암 및 감염성 질환의 치료 및 예방을 위한 바이러스 유전자 치료요법 및 면역 체크포인트 억제제를 포함하는 방법 및 조성물
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
WO2018156250A1
(en)
*
|
2017-02-21 |
2018-08-30 |
Remd Biotherapeutics, Inc. |
Cancer treatment using antibodies that bind cytotoxic t-lymphocyte antigen-4 (ctla-4)
|
|
EP3586136B1
(en)
|
2017-02-24 |
2023-11-08 |
Board Of Regents, The University Of Texas System |
Assay for detection of early stage pancreatic cancer
|
|
EP3366703B1
(en)
|
2017-02-28 |
2019-04-03 |
Ralf Kleef |
Immune checkpoint therapy with hyperthermia
|
|
WO2018160538A1
(en)
|
2017-02-28 |
2018-09-07 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
|
WO2018167780A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of prognosing and treating cancer
|
|
WO2018167778A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of diagnosing and prognosing cancer
|
|
JP7346300B2
(ja)
|
2017-03-23 |
2023-09-19 |
アボット・ラボラトリーズ |
早期バイオマーカーであるユビキチンカルボキシ末端ヒドロラーゼｌ１を使用する、ヒト対象における外傷性脳損傷の程度の診断及び決定の一助となるための方法
|
|
KR20250036268A
(ko)
|
2017-03-31 |
2025-03-13 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
BR112019021612A2
(pt)
|
2017-04-15 |
2020-05-12 |
Abbott Laboratories |
Métodos para auxiliar o diagnóstico hiperagudo e determinação de traumatismo crânioencefálico em um indivíduo humano com o uso de biomarcadores precoces
|
|
WO2018200430A1
(en)
|
2017-04-26 |
2018-11-01 |
Bristol-Myers Squibb Company |
Methods of antibody production that minimize disulfide bond reduction
|
|
EP3635407B1
(en)
|
2017-04-28 |
2025-09-10 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
|
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
|
EP3625255A4
(en)
*
|
2017-05-19 |
2021-02-24 |
Wuxi Biologics (Shanghai) Co. Ltd. |
NOVEL MONOCLONAL ANTIBODIES AGAINST CYTOTOXIC T-LYMPHOCYTE ASSOCIATED PROTEIN 4 (CTLA-4)
|
|
CN116478289A
(zh)
*
|
2017-05-19 |
2023-07-25 |
上海药明生物技术有限公司 |
一种新的ctla-4单克隆抗体
|
|
KR20240149979A
(ko)
|
2017-05-25 |
2024-10-15 |
브리스톨-마이어스 스큅 컴퍼니 |
변형된 중쇄 불변 영역을 포함하는 항체
|
|
WO2018218169A1
(en)
|
2017-05-25 |
2018-11-29 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
|
EP3631467A1
(en)
|
2017-05-30 |
2020-04-08 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a mild traumatic brain injury in a human subject using cardiac troponin i
|
|
BR112019018759A2
(pt)
|
2017-05-30 |
2020-05-05 |
Bristol-Myers Squibb Company |
composições compreendendo uma combinação de um anticorpo anti-lag-3, um inibidor da via pd-1, e um agente imunoterápico
|
|
PL3631454T3
(pl)
|
2017-05-30 |
2024-01-29 |
Bristol-Myers Squibb Company |
Leczenie guzów lag-3 pozytywnych
|
|
MX2019012076A
(es)
|
2017-05-30 |
2019-12-09 |
Bristol Myers Squibb Co |
Composiciones que comprenden un anticuerpo anti gen-3 de activacion del linfocito (lag-3) o un anticuerpo anti-lag-3 y un anticuerpo anti muerte celular programada 1 (pd-1) o anti ligando 1 de muerte celular programada (pd-l1).
|
|
AU2018281830B2
(en)
|
2017-06-09 |
2023-11-02 |
Agonox, Inc. |
Utilization of CD39 and CD103 for identification of human tumor reactive cells for treatment of cancer
|
|
JP7454945B2
(ja)
|
2017-07-03 |
2024-03-25 |
アボット・ラボラトリーズ |
血液中のユビキチンカルボキシ末端ヒドロラーゼｌ１レベルを測定するための、改善された方法
|
|
CA3069524A1
(en)
|
2017-07-14 |
2019-01-17 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
AR112336A1
(es)
|
2017-07-14 |
2019-10-16 |
Pfizer |
ANTICUERPOS CONTRA MAdCAM
|
|
TWI799432B
(zh)
*
|
2017-07-27 |
2023-04-21 |
美商再生元醫藥公司 |
抗ctla-4抗體及其用途
|
|
BR112020002280A2
(pt)
|
2017-08-03 |
2020-07-28 |
Otsuka Pharmaceutical Co., Ltd. |
composto farmacológico e métodos purificação do mesmo
|
|
WO2019036855A1
(en)
|
2017-08-21 |
2019-02-28 |
Adagene Inc. |
Anti-cd137 molecules and use thereof
|
|
US12195536B2
(en)
|
2017-10-06 |
2025-01-14 |
The Wistar Institute Of Anatomy And Biology |
DNA monoclonal antibodies targeting CTLA-4 for the treatment and prevention of cancer
|
|
EP3694552A1
(en)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
|
US12178787B2
(en)
|
2017-10-12 |
2024-12-31 |
Board Of Regents, The University Of Texas System |
T cell receptors for immunotherapy
|
|
JP2020536894A
(ja)
|
2017-10-15 |
2020-12-17 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
腫瘍処置法
|
|
WO2019089921A1
(en)
|
2017-11-01 |
2019-05-09 |
Bristol-Myers Squibb Company |
Immunostimulatory agonistic antibodies for use in treating cancer
|
|
KR20200085780A
(ko)
|
2017-11-07 |
2020-07-15 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
암의 치료에서 car-t 또는 car-nk 세포를 사용한 lilrb4 표적화
|
|
EP3717021A1
(en)
|
2017-11-27 |
2020-10-07 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
CN108003238B
(zh)
*
|
2017-11-30 |
2021-02-02 |
常州费洛斯药业科技有限公司 |
一种能特异识别ctla-4的全人源单克隆抗体或抗体片段及其方法和用途
|
|
EP3721234A1
(en)
|
2017-12-09 |
2020-10-14 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of gfap and uch-l1
|
|
WO2019113525A2
(en)
|
2017-12-09 |
2019-06-13 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
|
|
CA3085861C
(en)
*
|
2017-12-20 |
2023-09-26 |
Harbour Biomed (Shanghai) Co., Ltd |
Antibodies binding ctla-4 and uses thereof
|
|
WO2019126691A1
(en)
|
2017-12-21 |
2019-06-27 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
EP3732198A1
(en)
|
2017-12-27 |
2020-11-04 |
Bristol-Myers Squibb Company |
Anti-cd40 antibodies and uses thereof
|
|
US11865081B2
(en)
|
2017-12-29 |
2024-01-09 |
Virogin Biotech Canada Ltd. |
Oncolytic viral delivery of therapeutic polypeptides
|
|
KR102813913B1
(ko)
|
2018-01-12 |
2025-05-30 |
브리스톨-마이어스 스큅 컴퍼니 |
Tim3에 대한 항체 및 그의 용도
|
|
CN111629731A
(zh)
|
2018-01-22 |
2020-09-04 |
百时美施贵宝公司 |
治疗癌症的组合物和方法
|
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
|
EP3752194A4
(en)
|
2018-02-13 |
2022-03-16 |
Checkmate Pharmaceuticals, Inc. |
ANTI-TUMOR IMMUNOTHERAPY COMPOSITIONS AND METHODS
|
|
BR112020017701A2
(pt)
|
2018-03-12 |
2020-12-29 |
Zoetis Services Llc |
Anticorpos anti-ngf e métodos dos mesmos
|
|
CA3093742A1
(en)
|
2018-03-12 |
2019-09-19 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Use of caloric restriction mimetics for potentiating chemo-immunotherapy for the treatment of cancers
|
|
CN112020510B
(zh)
|
2018-03-19 |
2024-10-11 |
茂体外尔公司 |
包含用于治疗癌症的肿瘤抑制基因疗法和cd122/cd132激动剂的方法及组合物
|
|
US20230167177A1
(en)
*
|
2018-03-19 |
2023-06-01 |
WuXi Biologics Ireland Limited |
Novel anti-ctla-4 antibody polypeptide
|
|
BR112020019083A2
(pt)
|
2018-03-21 |
2020-12-29 |
Five Prime Therapeutics, Inc. |
Anticorpos, ácido nucleico, composições, célula e métodos para preparar um anticorpo, para tratar câncer, para tratar uma doença infecciosa, para tratar uma inflamação, para a identificação de um anticorpo, para melhorar a eficácia antitumoral de um anticorpo, para melhorar a farmacocinética de um anticorpo, para selecionar um anticorpo, para melhorar a eficácia de anticorpos, para isolar anticorpos, para detectar vista em uma amostra e para tratar câncer
|
|
SG11202008767XA
(en)
|
2018-03-23 |
2020-10-29 |
Bristol Myers Squibb Co |
Antibodies against mica and/or micb and uses thereof
|
|
US10760075B2
(en)
|
2018-04-30 |
2020-09-01 |
Snipr Biome Aps |
Treating and preventing microbial infections
|
|
EP3773685A1
(en)
|
2018-03-25 |
2021-02-17 |
SNIPR Biome ApS. |
Treating & preventing microbial infections
|
|
MX2020010121A
(es)
|
2018-03-27 |
2021-01-08 |
Univ Texas |
Compuestos con actividad antitumoral contra celulas de cancer que portan las mutaciones del exon 19 del receptor 2 del factor de crecimiento epidermico humano.
|
|
EP3774911A1
(en)
|
2018-03-30 |
2021-02-17 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
CA3096311A1
(en)
|
2018-04-09 |
2019-10-17 |
Checkmate Pharmaceuticals |
Packaging oligonucleotides into virus-like particles
|
|
TWI851572B
(zh)
|
2018-04-18 |
2024-08-11 |
美商山可爾股份有限公司 |
IL-15/IL-15Rα異二聚體Fc融合蛋白及其用途
|
|
SG11202010163QA
(en)
|
2018-04-18 |
2020-11-27 |
Xencor Inc |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
BR112020021539A2
(pt)
|
2018-04-25 |
2021-01-19 |
Innate Tumor Immunity, Inc. |
Moduladores de nlrp3
|
|
EP3810109B1
(en)
|
2018-05-31 |
2024-08-07 |
Peloton Therapeutics, Inc. |
Compounds and compositions for inhibiting cd73
|
|
CN112566643A
(zh)
|
2018-06-12 |
2021-03-26 |
加利福尼亚大学董事会 |
用于治疗癌症的单链双特异性嵌合抗原受体
|
|
PE20211604A1
(es)
|
2018-07-09 |
2021-08-23 |
Five Prime Therapeutics Inc |
Anticuerpos de union a ilt4
|
|
JP7700036B2
(ja)
|
2018-07-11 |
2025-06-30 |
ファイヴ プライム セラピューティクス インク |
酸性ｐＨでＶＩＳＴＡと結合する抗体
|
|
MX2021000165A
(es)
|
2018-07-11 |
2021-05-28 |
Actym Therapeutics Inc |
Cepas bacterianas inmunoestimuladoras modificadas y usos de las mismas.
|
|
JP7072715B2
(ja)
|
2018-07-20 |
2022-05-20 |
サーフィス オンコロジー インコーポレイテッド |
抗ｃｄ１１２ｒ組成物及び方法
|
|
EP3837014B1
(en)
|
2018-08-16 |
2022-10-19 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
CN112996567A
(zh)
|
2018-08-16 |
2021-06-18 |
先天肿瘤免疫公司 |
咪唑并[4,5-c]喹啉衍生的nlrp3-调节剂
|
|
AU2019321470A1
(en)
|
2018-08-16 |
2021-04-01 |
Innate Tumor Immunity, Inc. |
Substitued 4-amino-1H-Imidazo[4,5-C]Quinoline Compounds And Improved Methods For Their Preparation
|
|
EP3617230A1
(en)
|
2018-09-03 |
2020-03-04 |
BioInvent International AB |
Novel antibodies and nucleotide sequences, and uses thereof
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
CN113396160A
(zh)
|
2018-09-19 |
2021-09-14 |
国家医疗保健研究所 |
治疗对免疫检查点疗法具有抗性的癌症的方法和药物组合物
|
|
AU2019343251B2
(en)
|
2018-09-21 |
2022-06-09 |
Innovent Biologics (Suzhou) Co., Ltd. |
Novel interleukin 2 and use thereof
|
|
EP3854805A4
(en)
|
2018-09-21 |
2022-08-24 |
Innovent Biologics (Suzhou) Co., Ltd. |
NOVEL INTERLEUKIN 2 AND ITS USE
|
|
WO2020070053A1
(en)
|
2018-10-01 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
CN113195523A
(zh)
|
2018-10-03 |
2021-07-30 |
Xencor股份有限公司 |
IL-12异源二聚体Fc融合蛋白
|
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
|
AU2019359475A1
(en)
|
2018-10-12 |
2021-05-20 |
Xencor, Inc. |
PD-1 targeted IL-15/IL-15Ralpha Fc fusion proteins and uses in combination therapies thereof
|
|
WO2020086724A1
(en)
|
2018-10-23 |
2020-04-30 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3873534A1
(en)
|
2018-10-29 |
2021-09-08 |
Mersana Therapeutics, Inc. |
Cysteine engineered antibody-drug conjugates with peptide-containing linkers
|
|
AU2019377546A1
(en)
|
2018-11-09 |
2021-06-03 |
Pierian Biosciences, LLC |
Methods and compositions for determining the composition of a tumor microenvironment
|
|
US11274150B2
(en)
|
2018-11-16 |
2022-03-15 |
Bristol-Myers Squibb Company |
Anti-human natural killer cell inhibitory receptor group 2A protein (NKG2A) antibodies
|
|
CN113286813A
(zh)
|
2018-11-19 |
2021-08-20 |
得克萨斯大学体系董事会 |
用于car和tcr转导的模块化多顺反子载体
|
|
JP2022513653A
(ja)
|
2018-11-28 |
2022-02-09 |
ブリストル－マイヤーズ スクイブ カンパニー |
修飾された重鎖定常領域を含む抗体
|
|
SG11202105609RA
(en)
|
2018-11-28 |
2021-06-29 |
Univ Texas |
Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment
|
|
WO2020109355A1
(en)
|
2018-11-28 |
2020-06-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and kit for assaying lytic potential of immune effector cells
|
|
EP3886874B1
(en)
|
2018-11-29 |
2024-12-11 |
Board of Regents, The University of Texas System |
Methods for ex vivo expansion of natural killer cells and use thereof
|
|
US20220018835A1
(en)
|
2018-12-07 |
2022-01-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
BR112021011224A2
(pt)
|
2018-12-11 |
2021-08-24 |
Theravance Biopharma R&D Ip, Llc |
Inibidores de alk5
|
|
EP3897624A1
(en)
|
2018-12-17 |
2021-10-27 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of sulconazole as a furin inhibitor
|
|
US12384845B2
(en)
|
2018-12-26 |
2025-08-12 |
Xilio Development, Inc. |
Activatable masked anti-CTLA4 binding proteins
|
|
US20220056481A1
(en)
|
2018-12-28 |
2022-02-24 |
Transgene |
M2-defective poxvirus
|
|
JP7506080B2
(ja)
|
2019-01-14 |
2024-06-25 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
Ｎｌｒｐ３モジュレーター
|
|
WO2020150113A1
(en)
|
2019-01-14 |
2020-07-23 |
Innate Tumor Immunity, Inc. |
Substituted quinazolines as nlrp3 modulators, for use in the treatment of cancer
|
|
EP3911417B1
(en)
|
2019-01-14 |
2022-10-26 |
Innate Tumor Immunity, Inc. |
Heterocyclic nlrp3 modulators , for use in the treatment of cancer
|
|
CN113286786A
(zh)
|
2019-01-14 |
2021-08-20 |
先天肿瘤免疫公司 |
Nlrp3调节剂
|
|
CN113508129B
(zh)
|
2019-01-15 |
2025-02-18 |
法国国家健康和医学研究院 |
突变的白介素-34(il-34)多肽及其在治疗中的用途
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
US20220143161A1
(en)
|
2019-03-13 |
2022-05-12 |
Etherna Immunotherapies Nv |
Mrna vaccine
|
|
JP2022527177A
(ja)
|
2019-03-28 |
2022-05-31 |
ブリストル－マイヤーズ スクイブ カンパニー |
腫瘍を処置する方法
|
|
US20220195046A1
(en)
|
2019-03-28 |
2022-06-23 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
US20200318200A1
(en)
|
2019-04-02 |
2020-10-08 |
The Brigham And Women's Hospital, Inc. |
Methods for Identifying Progression of a Primary Melanoma
|
|
US20220177978A1
(en)
|
2019-04-02 |
2022-06-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting and preventing cancer in patients having premalignant lesions
|
|
EP3952850A1
(en)
|
2019-04-09 |
2022-02-16 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
|
US20220220480A1
(en)
|
2019-04-17 |
2022-07-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
|
CN114144514A
(zh)
|
2019-05-09 |
2022-03-04 |
富士胶片细胞动力公司 |
产生肝细胞的方法
|
|
EP3968971A1
(en)
|
2019-05-17 |
2022-03-23 |
Cancer Prevention Pharmaceuticals, Inc. |
Methods for treating familial adenomatous polyposis
|
|
US20220363760A1
(en)
|
2019-05-30 |
2022-11-17 |
Bristol-Myers Squibb Company |
Multi-tumor gene signature for suitability to immuno-oncology therapy
|
|
EP3976832A1
(en)
|
2019-05-30 |
2022-04-06 |
Bristol-Myers Squibb Company |
Methods of identifying a subject suitable for an immuno-oncology (i-o) therapy
|
|
US20220233691A1
(en)
|
2019-05-30 |
2022-07-28 |
Bristol-Myers Squibb Company |
Cell localization signature and combination therapy
|
|
US20220298225A1
(en)
|
2019-06-03 |
2022-09-22 |
The University Of Chicago |
Methods and compositions for treating cancer with collagen binding drug carriers
|
|
CA3144533A1
(en)
|
2019-06-03 |
2020-12-10 |
The University Of Chicago |
Methods and compositions for treating cancer with cancer-targeted adjuvants
|
|
US20210038684A1
(en)
|
2019-06-11 |
2021-02-11 |
Alkermes Pharma Ireland Limited |
Compositions and Methods for Cancer Immunotherapy
|
|
JP2022540759A
(ja)
|
2019-06-27 |
2022-09-20 |
イーザアールエヌーエー イムノセラピーズ エンヴェー |
併用療法
|
|
WO2021003432A1
(en)
|
2019-07-02 |
2021-01-07 |
Fred Hutchinson Cancer Research Center |
Recombinant ad35 vectors and related gene therapy improvements
|
|
CA3145347A1
(en)
|
2019-07-15 |
2021-01-21 |
Intervet International B.V. |
Caninized antibodies to human and canine ctla-4
|
|
JP2022542808A
(ja)
|
2019-07-15 |
2022-10-07 |
インターベット インターナショナル ベー． フェー． |
イヌｃｔｌａ－４に対するイヌ化抗体
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
JPWO2021024742A1
(OSRAM)
*
|
2019-08-06 |
2021-02-11 |
|
|
|
EP4031535A1
(en)
|
2019-09-17 |
2022-07-27 |
Bial-R&D Investments, S.A. |
Substituted n-heterocyclic carboxamides as acid ceramidase inhibitors and their use as medicaments
|
|
WO2021055612A1
(en)
|
2019-09-17 |
2021-03-25 |
BIAL-BioTech Investments, Inc. |
Substituted imidazole carboxamides and their use in the treatment of medical disorders
|
|
CA3150906A1
(en)
|
2019-09-17 |
2021-03-25 |
Renato T. Skerlj |
Substituted, saturated and unsaturated n-heterocyclic carboxamides and related compounds for their use in the treatment of medical disorders
|
|
BR112022004831A2
(pt)
|
2019-09-19 |
2022-06-07 |
Bristol Myers Squibb Co |
Anticorpos que se ligam a vista em ph ácido
|
|
MX2022003197A
(es)
|
2019-09-22 |
2022-04-11 |
Bristol Myers Squibb Co |
Perfilado espacial cuantitativo para terapia con antagonistas de la proteina del gen de activacion de linfocitos 3 (lag-3).
|
|
AU2020356463A1
(en)
|
2019-09-23 |
2022-04-07 |
The Regents Of The University Of Michigan |
Compositions and methods for increasing the efficacy of immunotherapies and vaccines
|
|
JP2022549854A
(ja)
|
2019-09-25 |
2022-11-29 |
サーフィス オンコロジー インコーポレイテッド |
抗ｉｌ－２７抗体及びその使用
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
CA3157024A1
(en)
|
2019-10-03 |
2021-04-08 |
Xencor, Inc. |
Targeted il-12 heterodimeric fc-fusion proteins
|
|
EP4037710A1
(en)
|
2019-10-04 |
2022-08-10 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
CA3155172A1
(en)
|
2019-10-25 |
2021-04-29 |
Shinko HAYASHI |
Combination of anti-garp antibody and immunomodulator
|
|
US20220380765A1
(en)
|
2019-11-02 |
2022-12-01 |
Board Of Regents, The University Of Texas System |
Targeting nonsense-mediated decay to activate p53 pathway for the treatment of cancer
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
KR20220093349A
(ko)
|
2019-11-08 |
2022-07-05 |
브리스톨-마이어스 스큅 컴퍼니 |
흑색종에 대한 lag-3 길항제 요법
|
|
TW202132297A
(zh)
|
2019-11-22 |
2021-09-01 |
美商施萬生物製藥研發Ｉｐ有限責任公司 |
經取代吡啶及使用方法
|
|
TW202128155A
(zh)
|
2019-11-27 |
2021-08-01 |
日商賽多利克公司 |
醫藥組成物
|
|
WO2021113644A1
(en)
|
2019-12-05 |
2021-06-10 |
Multivir Inc. |
Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer
|
|
AU2020407130A1
(en)
|
2019-12-19 |
2022-06-16 |
Bristol-Myers Squibb Company |
Combinations of DGK inhibitors and checkpoint antagonists
|
|
EP4082570A4
(en)
|
2019-12-27 |
2023-09-13 |
Chugai Seiyaku Kabushiki Kaisha |
ANTI-CTLA-4 ANTIBODY AND ITS USE
|
|
AU2021206202A1
(en)
|
2020-01-07 |
2022-06-30 |
Board Of Regents, The University Of Texas System |
Improved human methylthioadenosine/adenosine depleting enzyme variants for cancer therapy
|
|
EP4087842A1
(en)
|
2020-01-10 |
2022-11-16 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
WO2021159024A1
(en)
|
2020-02-05 |
2021-08-12 |
Larimar Therapeutics, Inc. |
Tat peptide binding proteins and uses thereof
|
|
WO2021158938A1
(en)
|
2020-02-06 |
2021-08-12 |
Bristol-Myers Squibb Company |
Il-10 and uses thereof
|
|
US20230106973A1
(en)
|
2020-02-17 |
2023-04-06 |
Board Of Regents, The University Of Texas System |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
|
EP4110810A1
(en)
|
2020-02-28 |
2023-01-04 |
Orega Biotech |
Combination therapies based on ctla4 and il-17b inhibitors
|
|
WO2022074464A2
(en)
|
2020-03-05 |
2022-04-14 |
Neotx Therapeutics Ltd. |
Methods and compositions for treating cancer with immune cells
|
|
EP4118118A1
(en)
|
2020-03-09 |
2023-01-18 |
Bristol-Myers Squibb Company |
Antibodies to cd40 with enhanced agonist activity
|
|
JP2023519346A
(ja)
|
2020-03-27 |
2023-05-10 |
メンドゥス・ベスローテン・フェンノートシャップ |
養子細胞療法の有効性を増強するための白血病由来の改変細胞のエクスビボ（ｅｘ ｖｉｖｏ）使用
|
|
TW202204339A
(zh)
|
2020-03-31 |
2022-02-01 |
美商施萬生物製藥研發 Ip有限責任公司 |
經取代的嘧啶及使用方法
|
|
WO2021207449A1
(en)
|
2020-04-09 |
2021-10-14 |
Merck Sharp & Dohme Corp. |
Affinity matured anti-lap antibodies and uses thereof
|
|
EP4136459A1
(en)
|
2020-04-13 |
2023-02-22 |
Abbott Laboratories |
Methods, complexes and kits for detecting or determining an amount of a ss-coronavirus antibody in a sample
|
|
EP4139289A1
(en)
|
2020-04-21 |
2023-03-01 |
University of Rochester |
Inhibitors of human epididymus protein 4
|
|
KR20230037069A
(ko)
|
2020-04-22 |
2023-03-15 |
이오반스 바이오테라퓨틱스, 인크. |
환자-특이적 면역요법을 위해 세포의 제조를 조정하기 위한 시스템 및 방법
|
|
CN115768525A
(zh)
|
2020-05-13 |
2023-03-07 |
天演药业(瑞士)公司 |
用于治疗癌症的组合物和方法
|
|
JP2023528223A
(ja)
|
2020-05-13 |
2023-07-04 |
ディスク・メディシン・インコーポレイテッド |
骨髄線維症を処置するための抗ヘモジュベリン（ｈｊｖ）抗体
|
|
WO2021231732A1
(en)
|
2020-05-15 |
2021-11-18 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
US20230212256A1
(en)
|
2020-05-21 |
2023-07-06 |
Board Of Regents, The University Of Texas System |
T cell receptors with vgll1 specificity and uses thereof
|
|
CN115803062B
(zh)
|
2020-06-03 |
2025-09-09 |
博泰康医药公司 |
滋养层细胞表面抗原2(trop-2)抗体
|
|
WO2021247836A1
(en)
|
2020-06-03 |
2021-12-09 |
Board Of Regents, The University Of Texas System |
Methods for targeting shp-2 to overcome resistance
|
|
JP2023528071A
(ja)
|
2020-06-03 |
2023-07-03 |
エムヴィ バイオセラピューティクス エスエー |
Ａｔｐ加水分解酵素と免疫チェックポイントモジュレーターとの組合せ、並びにその使用
|
|
TW202214623A
(zh)
|
2020-06-10 |
2022-04-16 |
美商施萬生物製藥研發 Ip有限責任公司 |
結晶型alk5抑制劑及其用途
|
|
WO2021260675A1
(en)
|
2020-06-24 |
2021-12-30 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
|
CN116133679A
(zh)
|
2020-06-30 |
2023-05-16 |
门德斯有限公司 |
白血病衍生细胞在卵巢癌疫苗中的用途
|
|
WO2022003156A1
(en)
|
2020-07-02 |
2022-01-06 |
Oncurious Nv |
Ccr8 non-blocking binders
|
|
TW202216776A
(zh)
|
2020-07-07 |
2022-05-01 |
美商康愈有限責任公司 |
Mic抗體及結合劑以及其使用方法
|
|
WO2022008519A1
(en)
|
2020-07-07 |
2022-01-13 |
BioNTech SE |
Therapeutic rna for hpv-positive cancer
|
|
US20230295146A1
(en)
|
2020-07-24 |
2023-09-21 |
The University Of Rochester |
Inhibitors of interleukin-1 receptor-associated kinases 1 and 4
|
|
CA3189336A1
(en)
|
2020-07-24 |
2022-01-27 |
Amgen Inc. |
Immunogens derived from sars-cov2 spike protein
|
|
WO2022031804A1
(en)
|
2020-08-04 |
2022-02-10 |
Abbott Laboratories |
Improved methods and kits for detecting sars-cov-2 protein in a sample
|
|
CN112359052B
(zh)
*
|
2020-08-20 |
2023-01-03 |
山东兴瑞生物科技有限公司 |
抗EpCAM嵌合抗原受体的编码基因、制备方法、具有该基因的质粒、免疫细胞及其应用
|
|
JP2023540255A
(ja)
|
2020-08-28 |
2023-09-22 |
ブリストル－マイヤーズ スクイブ カンパニー |
肝細胞癌のためのｌａｇ－３アンタゴニスト療法
|
|
MX2023002326A
(es)
|
2020-08-31 |
2023-03-21 |
Bristol Myers Squibb Co |
Firma de localizacion celular e inmunoterapia.
|
|
US20240101666A1
(en)
|
2020-10-23 |
2024-03-28 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for lung cancer
|
|
CA3200661A1
(en)
|
2020-11-05 |
2022-05-12 |
Board Of Regents, The University Of Texas System |
Engineered t cell receptors targeting egfr antigens and methods of use
|
|
CA3201499A1
(en)
|
2020-11-13 |
2022-05-19 |
Catamaran Bio, Inc. |
Genetically modified natural killer cells and methods of use thereof
|
|
EP4251645A1
(en)
|
2020-11-25 |
2023-10-04 |
Catamaran Bio, Inc. |
Cellular therapeutics engineered with signal modulators and methods of use thereof
|
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
US20220170948A1
(en)
|
2020-12-01 |
2022-06-02 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a human subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
PH12023500013A1
(en)
|
2020-12-04 |
2024-03-11 |
Tidal Therapeutics Inc |
Ionizable cationic lipids and lipi nanoparticles, and methods of synthesis and use thereof
|
|
KR20230119179A
(ko)
*
|
2020-12-10 |
2023-08-16 |
우시 바이올로직스 아일랜드 리미티드 |
P-캐드히린에 대한 항체 및 이의 용도
|
|
WO2022130206A1
(en)
|
2020-12-16 |
2022-06-23 |
Pfizer Inc. |
TGFβr1 INHIBITOR COMBINATION THERAPIES
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性ｒｎａ
|
|
WO2022136650A1
(en)
|
2020-12-24 |
2022-06-30 |
Oncurious Nv |
Murine cross-reactive human ccr8 binders
|
|
EP4267617A1
(en)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Human ccr8 binders
|
|
EP4267618A1
(en)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Non-blocking human ccr8 binders
|
|
AU2021411486A1
(en)
|
2020-12-28 |
2023-06-29 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
EP4267172A1
(en)
|
2020-12-28 |
2023-11-01 |
Bristol-Myers Squibb Company |
Subcutaneous administration of pd1/pd-l1 antibodies
|
|
EP4271998A1
(en)
|
2020-12-30 |
2023-11-08 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
|
WO2022159492A1
(en)
|
2021-01-19 |
2022-07-28 |
William Marsh Rice University |
Bone-specific delivery of polypeptides
|
|
CA3203705A1
(en)
|
2021-01-22 |
2022-07-28 |
Erik Hans MANTING |
Methods of tumor vaccination
|
|
KR20230150295A
(ko)
|
2021-01-29 |
2023-10-30 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
키나제 억제제를 이용한 암의 치료 방법
|
|
KR20230157388A
(ko)
|
2021-03-12 |
2023-11-16 |
멘두스 비.브이. |
백신접종의 방법 및 cd47 차단의 용도
|
|
WO2022212876A1
(en)
|
2021-04-02 |
2022-10-06 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
US20240279225A1
(en)
|
2021-04-08 |
2024-08-22 |
Board Of Regents, The University Of Texas System |
Compounds and methods for theranostic targeting of parp activity
|
|
EP4070799A1
(en)
|
2021-04-08 |
2022-10-12 |
Nuvamid SA |
Compositions for the improvement of sport performance
|
|
TW202304524A
(zh)
|
2021-04-10 |
2023-02-01 |
美商普方生物製藥美國公司 |
Folr1結合劑、其結合物及使用方法
|
|
EP4079311B1
(en)
|
2021-04-20 |
2025-10-01 |
Nuvamid SA |
Nmn and derivatives for use in the treatment of depression and/or anxiety in patients having a form of parkinsonism
|
|
EP4079310A1
(en)
|
2021-04-20 |
2022-10-26 |
Nuvamid SA |
Nmn and derivatives for its use in the treatment of alpha-synucleinopathies
|
|
JP2024517131A
(ja)
|
2021-04-20 |
2024-04-19 |
アンスティテュ・クリー |
免疫療法における使用のための組成物及び方法
|
|
AU2022262644A1
(en)
|
2021-04-23 |
2023-11-09 |
Genmab A/S |
Anti-cd70 antibodies, conjugates thereof and methods of using the same
|
|
AU2022279156A1
(en)
|
2021-05-18 |
2023-11-02 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
|
WO2022251359A1
(en)
|
2021-05-26 |
2022-12-01 |
Theravance Biopharma R&D Ip, Llc |
Bicyclic inhibitors of alk5 and methods of use
|
|
CA3218590A1
(en)
|
2021-06-07 |
2022-12-15 |
Providence Health & Services - Oregon |
Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use
|
|
EP4356129A1
(en)
|
2021-06-14 |
2024-04-24 |
Abbott Laboratories |
Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
|
|
US20240002510A2
(en)
|
2021-06-25 |
2024-01-04 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-ctla-4 antibody and use thereof
|
|
MX2023014453A
(es)
|
2021-06-25 |
2024-01-31 |
Chugai Pharmaceutical Co Ltd |
Uso de anticuerpos anti-antigeno 4 del linfocito t citotoxico (anti-ctla-4).
|
|
CN117616123B
(zh)
|
2021-06-25 |
2024-11-08 |
中外制药株式会社 |
抗ctla-4抗体
|
|
WO2023280790A1
(en)
|
2021-07-05 |
2023-01-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
IL309831A
(en)
|
2021-07-13 |
2024-02-01 |
BioNTech SE |
Multispecific binding agents against CD40 and CD137 in combined cancer therapy
|
|
US20250114452A1
(en)
|
2021-08-04 |
2025-04-10 |
The Regents Of The University Of Colorado, A Body Corporate |
Lat activating chimeric antigen receptor t cells and methods of use thereof
|
|
WO2023028501A1
(en)
|
2021-08-23 |
2023-03-02 |
Immunitas Therapeutics, Inc. |
Anti-cd161 antibodies and uses thereof
|
|
CN118715440A
(zh)
|
2021-08-31 |
2024-09-27 |
雅培实验室 |
诊断脑损伤的方法和系统
|
|
AU2022339759A1
(en)
|
2021-08-31 |
2024-03-07 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
EP4409294A1
(en)
|
2021-09-30 |
2024-08-07 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
AU2022361488A1
(en)
|
2021-10-05 |
2024-05-02 |
Cytovia Therapeutics, Llc |
Natural killer cells and methods of use thereof
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
TW202330612A
(zh)
|
2021-10-20 |
2023-08-01 |
日商武田藥品工業股份有限公司 |
靶向ｂｃｍａ之組合物及其使用方法
|
|
WO2023076880A1
(en)
|
2021-10-25 |
2023-05-04 |
Board Of Regents, The University Of Texas System |
Foxo1-targeted therapy for the treatment of cancer
|
|
US20240417473A1
(en)
|
2021-10-29 |
2024-12-19 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hematological cancer
|
|
WO2023092099A1
(en)
|
2021-11-19 |
2023-05-25 |
Ardeagen Corporation |
Gpc3 binding agents, conjugates thereof and methods of using the same
|
|
KR20240123846A
(ko)
*
|
2021-11-24 |
2024-08-14 |
다나-파버 캔서 인스티튜트 인크. |
Ctla-4에 대한 항체 및 이의 사용 방법
|
|
EP4448179A1
(en)
|
2021-12-17 |
2024-10-23 |
Abbott Laboratories |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
|
TW202332687A
(zh)
|
2021-12-23 |
2023-08-16 |
比利時商ｅＴｈｅＲＮＡ免疫治療公司 |
免疫刺激性mrna組成物及其用途
|
|
JP2025503962A
(ja)
|
2022-01-26 |
2025-02-06 |
ブリストル－マイヤーズ スクイブ カンパニー |
肝細胞がんのための併用療法
|
|
CN119256227A
(zh)
|
2022-02-04 |
2025-01-03 |
雅培实验室 |
用于检测样品中泛素羧基末端水解酶l1和/或胶质纤维酸性蛋白的存在或测量其量的侧向流方法、测定和装置
|
|
AU2023226078A1
(en)
|
2022-02-25 |
2024-08-22 |
Bristol-Myers Squibb Company |
Combination therapy for colorectal carcinoma.
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
WO2023170606A1
(en)
|
2022-03-08 |
2023-09-14 |
Alentis Therapeutics Ag |
Use of anti-claudin-1 antibodies to increase t cell availability
|
|
CR20240379A
(es)
|
2022-03-15 |
2024-12-11 |
Compugen Ltd |
Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia combinada en el tratamiento del cáncer
|
|
KR20240161968A
(ko)
|
2022-03-16 |
2024-11-13 |
다이이찌 산쿄 가부시키가이샤 |
다중 특이적 분자와 면역 체크 포인트 저해제의 조합
|
|
EP4493575A1
(en)
|
2022-03-18 |
2025-01-22 |
Bristol-Myers Squibb Company |
Methods of isolating polypeptides
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
JP2025512401A
(ja)
|
2022-04-15 |
2025-04-17 |
アイオバンス バイオセラピューティクス，インコーポレイテッド |
特定のサイトカインの組み合わせ及び／またはＡＫＴｉ処理を使用したＴＩＬ拡張プロセス
|
|
WO2023211972A1
(en)
|
2022-04-28 |
2023-11-02 |
Medical University Of South Carolina |
Chimeric antigen receptor modified regulatory t cells for treating cancer
|
|
WO2023213763A1
(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
|
|
WO2023213764A1
(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
|
|
EP4531927A1
(en)
|
2022-05-24 |
2025-04-09 |
Daiichi Sankyo Company, Limited |
Dosage regimen of an anti-cdh6 antibody-drug conjugate
|
|
AU2023281061A1
(en)
|
2022-06-02 |
2024-12-05 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
CN119630637A
(zh)
|
2022-06-08 |
2025-03-14 |
潮汐疗法公司 |
可电离阳离子脂质和脂质纳米颗粒及其合成和使用方法
|
|
GB202209518D0
(en)
|
2022-06-29 |
2022-08-10 |
Snipr Biome Aps |
Treating & preventing E coli infections
|
|
CN120167040A
(zh)
|
2022-06-29 |
2025-06-17 |
雅培实验室 |
用于确定生物样本中的gfap的磁性定点照护型系统和测定
|
|
CN119654339A
(zh)
|
2022-07-01 |
2025-03-18 |
特兰斯吉恩股份有限公司 |
包含表面活性蛋白-d和tnfsf成员的融合蛋白
|
|
TW202412859A
(zh)
|
2022-07-28 |
2024-04-01 |
英商阿斯特捷利康英國股份有限公司 |
抗體-藥物結合物及雙特異性檢查點抑制劑之組合
|
|
WO2024028794A1
(en)
|
2022-08-02 |
2024-02-08 |
Temple Therapeutics BV |
Methods for treating endometrial and ovarian hyperproliferative disorders
|
|
WO2024052356A1
(en)
|
2022-09-06 |
2024-03-14 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
|
EP4587842A1
(en)
|
2022-09-15 |
2025-07-23 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|
|
WO2024086827A2
(en)
|
2022-10-20 |
2024-04-25 |
Repertoire Immune Medicines, Inc. |
Cd8 t cell targeted il2
|
|
AU2023385185A1
(en)
|
2022-11-21 |
2025-05-08 |
Iovance Biotherapeutics, Inc. |
Two-dimensional processes for the expansion of tumor infiltrating lymphocytes and therapies therefrom
|
|
IL321098A
(en)
|
2022-12-14 |
2025-07-01 |
Astellas Pharma Europe Bv |
Combination therapy including bispecific binding agents that bind to CLDN18.2- and CD3- and immune checkpoint inhibitors
|
|
WO2024137776A1
(en)
|
2022-12-21 |
2024-06-27 |
Bristol-Myers Squibb Company |
Combination therapy for lung cancer
|
|
WO2024163477A1
(en)
|
2023-01-31 |
2024-08-08 |
University Of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024211475A1
(en)
|
2023-04-04 |
2024-10-10 |
Abbott Laboratories |
Use of biomarkers to determine whether a subject has sustained, may have sustained or is suspected of sustaining a subacute acquired brain injury (abi)
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
WO2024226969A1
(en)
|
2023-04-28 |
2024-10-31 |
Abbott Point Of Care Inc. |
Improved assays, cartridges, and kits for detection of biomarkers, including brain injury biomarkers
|
|
WO2024261302A1
(en)
|
2023-06-22 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Nlrp3 inhibitors, pak1/2 inhibitors and/or caspase 1 inhibitors for use in the treatment of rac2 monogenic disorders
|
|
TW202515608A
(zh)
|
2023-06-26 |
2025-04-16 |
以色列商坎布根有限公司 |
Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途
|
|
EP4484445A1
(en)
|
2023-06-26 |
2025-01-01 |
Universität zu Köln |
Hcmv neutralizing antibodies
|
|
WO2025003193A1
(en)
|
2023-06-26 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Sertraline and indatraline for disrupting intracellular cholesterol trafficking and subsequently inducing lysosomal damage and anti-tumor immunity
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
WO2025050009A2
(en)
|
2023-09-01 |
2025-03-06 |
Children's Hospital Medical Center |
Identification of targets for immunotherapy in melanoma using splicing-derived neoantigens
|
|
EP4590714A1
(en)
|
2023-09-21 |
2025-07-30 |
Domain Therapeutics |
Anti-ccr8 monoclonal antibodies and their therapeutic use
|
|
WO2025061994A1
(en)
|
2023-09-21 |
2025-03-27 |
Domain Therapeutics |
Anti-ccr8 monoclonal antibodies and their therapeutic use
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
EP4574165A1
(en)
|
2023-12-21 |
2025-06-25 |
Egle Therapeutics |
Immunocytokine for cancer treatment
|
|
WO2025133175A1
(en)
|
2023-12-21 |
2025-06-26 |
Egle Therapeutics |
Immunocytokine for cancer treatment
|
|
WO2025145207A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg-depleting agent
|
|
WO2025174825A2
(en)
|
2024-02-12 |
2025-08-21 |
Aera Therapeutics, Inc. |
Delivery compositions
|
|
WO2025184211A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|