NZ582018A - Multipotent/pluripotent cells and methods - Google Patents
Multipotent/pluripotent cells and methodsInfo
- Publication number
- NZ582018A NZ582018A NZ582018A NZ58201808A NZ582018A NZ 582018 A NZ582018 A NZ 582018A NZ 582018 A NZ582018 A NZ 582018A NZ 58201808 A NZ58201808 A NZ 58201808A NZ 582018 A NZ582018 A NZ 582018A
- Authority
- NZ
- New Zealand
- Prior art keywords
- multipotent
- methods
- pluripotent cells
- polypeptide
- stem cell
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007159382A JP2008307007A (ja) | 2007-06-15 | 2007-06-15 | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| PCT/EP2007/010019 WO2009006930A1 (en) | 2007-06-15 | 2007-11-20 | Human pluripotent stem cells induced from undifferentiated stem cells derived from a human postnatal tissue |
| US4064608P | 2008-03-28 | 2008-03-28 | |
| PCT/IB2008/002540 WO2009007852A2 (en) | 2007-06-15 | 2008-06-13 | Multipotent/pluripotent cells and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ582018A true NZ582018A (en) | 2012-05-25 |
Family
ID=39253880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ582018A NZ582018A (en) | 2007-06-15 | 2008-06-13 | Multipotent/pluripotent cells and methods |
Country Status (15)
| Country | Link |
|---|---|
| US (9) | US20110039332A1 (enExample) |
| EP (4) | EP2164952B1 (enExample) |
| JP (2) | JP2008307007A (enExample) |
| KR (1) | KR101657318B1 (enExample) |
| CN (1) | CN102317448B (enExample) |
| AP (1) | AP2010005102A0 (enExample) |
| AU (1) | AU2008273817B2 (enExample) |
| CA (1) | CA2690629A1 (enExample) |
| GB (2) | GB2450603B (enExample) |
| IL (1) | IL202678A (enExample) |
| MX (1) | MX2009013706A (enExample) |
| MY (1) | MY159971A (enExample) |
| NZ (1) | NZ582018A (enExample) |
| WO (3) | WO2009006930A1 (enExample) |
| ZA (1) | ZA200908904B (enExample) |
Families Citing this family (435)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| EP4248752A3 (en) * | 2004-01-23 | 2024-01-03 | President And Fellows Of Harvard College | Improved modalities for the treatment of degenerative diseases of the retina |
| WO2007026353A2 (en) | 2005-08-29 | 2007-03-08 | Technion Research & Development Foundation Ltd. | Media for culturing stem cells |
| AU2006325975B2 (en) * | 2005-12-13 | 2011-12-08 | Kyoto University | Nuclear reprogramming factor |
| US8129187B2 (en) * | 2005-12-13 | 2012-03-06 | Kyoto University | Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2 |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| US20090227032A1 (en) | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
| EP2377925A1 (en) | 2006-04-14 | 2011-10-19 | Advanced Cell Technology, Inc. | Hemangio-colony forming cells |
| EP2733203B1 (en) | 2006-08-02 | 2018-10-10 | Technion Research & Development Foundation Ltd. | Methods of expanding embryonic stem cells in a suspension culture |
| DK3399025T3 (da) | 2007-03-23 | 2025-06-16 | Wisconsin Alumni Res Found | Omprogrammering af somatiske celler |
| US9213999B2 (en) | 2007-06-15 | 2015-12-15 | Kyoto University | Providing iPSCs to a customer |
| US9029147B2 (en) | 2007-06-15 | 2015-05-12 | Massachusetts Institute Of Technology | Methods and compositions for enhanced differentiation from embryonic stem cells |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| KR101849329B1 (ko) | 2007-10-12 | 2018-04-16 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | Rpe 세포의 개선된 생산 방법 및 rpe 세포의 조성물 |
| US9683232B2 (en) | 2007-12-10 | 2017-06-20 | Kyoto University | Efficient method for nuclear reprogramming |
| JP5558097B2 (ja) * | 2007-12-10 | 2014-07-23 | 国立大学法人京都大学 | 効率的な核初期化方法 |
| WO2009085196A1 (en) * | 2007-12-21 | 2009-07-09 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with prostate cancer risk |
| US8986696B2 (en) | 2007-12-21 | 2015-03-24 | Depuy Mitek, Inc. | Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints |
| WO2009086425A1 (en) * | 2007-12-28 | 2009-07-09 | Fate Therapeutics, Inc. | Methods for reprogramming cells to a pluripotent state and therapeutic applications related thereto |
| US20110014164A1 (en) * | 2008-02-15 | 2011-01-20 | President And Fellows Of Harvard College | Efficient induction of pluripotent stem cells using small molecule compounds |
| WO2009117439A2 (en) | 2008-03-17 | 2009-09-24 | The Scripps Research Institute | Combined chemical and genetic approaches for generation of induced pluripotent stem cells |
| US20100279404A1 (en) * | 2008-05-02 | 2010-11-04 | Shinya Yamanaka | Method of nuclear reprogramming |
| KR20180127528A (ko) * | 2008-05-06 | 2018-11-28 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 혈관 콜로니 형성 세포 및 비-생착성 혈관 세포 |
| KR20210003301A (ko) * | 2008-05-06 | 2021-01-11 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 다능성 줄기세포로부터 유도된 탈핵 적혈구계 세포를 생산하는 방법 |
| CA2723726C (en) * | 2008-05-13 | 2017-09-12 | Michael M. Becker | Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences |
| EP3447128A1 (en) | 2008-06-04 | 2019-02-27 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of ips cells using non-viral approach |
| US8669048B2 (en) | 2008-06-24 | 2014-03-11 | Parkinson's Institute | Pluripotent cell lines and methods of use thereof |
| EP2295538B1 (en) * | 2008-07-07 | 2015-10-21 | Takara Bio Inc. | Method for production of pluripotent stem cell |
| JP5553178B2 (ja) * | 2008-07-31 | 2014-07-16 | 国立大学法人岐阜大学 | 効率的な人工多能性幹細胞の樹立方法 |
| EP2331696A1 (en) | 2008-08-12 | 2011-06-15 | Cellular Dynamics International, Inc. | Methods for the production of ips cells |
| US20120189595A1 (en) * | 2008-09-25 | 2012-07-26 | Salk Institute For Biological Studies | Induced pluripotent stem cells and methods of use |
| WO2010042669A2 (en) * | 2008-10-07 | 2010-04-15 | Ipierian, Inc. | Co-culture compositions and methods |
| EP3450545B1 (en) * | 2008-10-24 | 2023-08-23 | Wisconsin Alumni Research Foundation | Pluripotent stem cells obtained by non-viral reprogramming |
| US20110023139A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of genes involved in cardiovascular disease |
| US20110016546A1 (en) * | 2008-12-04 | 2011-01-20 | Sigma-Aldrich Co. | Porcine genome editing with zinc finger nucleases |
| US20110023147A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of prion disorder-related genes in animals |
| US20110023146A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of genes involved in secretase-associated disorders |
| US20110023140A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Rabbit genome editing with zinc finger nucleases |
| US20110023145A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of genes involved in autism spectrum disorders |
| US20110016543A1 (en) * | 2008-12-04 | 2011-01-20 | Sigma-Aldrich Co. | Genomic editing of genes involved in inflammation |
| US20110023148A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genome editing of addiction-related genes in animals |
| US20110023144A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of genes involved in amyotrophyic lateral sclerosis disease |
| US20110023143A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of neurodevelopmental genes in animals |
| US20110023141A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of genes involved with parkinson's disease |
| US20110023152A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genome editing of cognition related genes in animals |
| US20110023156A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Feline genome editing with zinc finger nucleases |
| US20110016540A1 (en) * | 2008-12-04 | 2011-01-20 | Sigma-Aldrich Co. | Genome editing of genes associated with trinucleotide repeat expansion disorders in animals |
| US20110023149A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of genes involved in tumor suppression in animals |
| US20110016539A1 (en) * | 2008-12-04 | 2011-01-20 | Sigma-Aldrich Co. | Genome editing of neurotransmission-related genes in animals |
| US20110023153A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of genes involved in alzheimer's disease |
| US20110023150A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genome editing of genes associated with schizophrenia in animals |
| US20110030072A1 (en) * | 2008-12-04 | 2011-02-03 | Sigma-Aldrich Co. | Genome editing of immunodeficiency genes in animals |
| US20110023151A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genome editing of abc transporters |
| US20110023154A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Silkworm genome editing with zinc finger nucleases |
| US20110016541A1 (en) * | 2008-12-04 | 2011-01-20 | Sigma-Aldrich Co. | Genome editing of sensory-related genes in animals |
| US20110023158A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Bovine genome editing with zinc finger nucleases |
| SG172160A1 (en) | 2008-12-17 | 2011-07-28 | Scripps Research Inst | Generation and maintenance of stem cells |
| CN101792776B (zh) * | 2009-02-01 | 2013-12-11 | 中国人民解放军第二军医大学东方肝胆外科医院 | 一种高效诱导多能性干细胞的重组腺病毒载体、使用该载体的诱导方法及其用途 |
| CA2753208C (en) * | 2009-02-20 | 2018-08-21 | Cellular Dynamics International, Inc. | Methods and compositions for the differentiation of stem cells |
| CA2753845C (en) * | 2009-02-27 | 2019-10-29 | Kyoto University | Nuclear reprogramming substance comprising glis1 |
| WO2010099539A1 (en) | 2009-02-27 | 2010-09-02 | Cellular Dynamics International, Inc. | Differentiation of pluripotent cells |
| EP2408904B1 (en) * | 2009-03-20 | 2017-10-18 | Mesoblast, Inc. | Production of reprogrammed pluripotent cells |
| KR20110134939A (ko) * | 2009-04-03 | 2011-12-15 | 더 맥클린 하스피털 코퍼레이션 | 유도된 다능성 줄기 세포 |
| RU2399667C1 (ru) * | 2009-04-10 | 2010-09-20 | Общество С Ограниченной Ответственностью "Лаборатория Клеточных Технологий" | Способ получения плюрипотентных клеток |
| JPWO2010119819A1 (ja) | 2009-04-17 | 2012-10-22 | 国立大学法人東北大学 | ヒト肺組織幹細胞の調製方法及びヒト肺胞上皮細胞への分化誘導方法 |
| CN101580816B (zh) * | 2009-04-23 | 2012-02-29 | 中国科学院广州生物医药与健康研究院 | 诱导多能性干细胞快速高效产生的新型无血清培养基以及使用其的方法 |
| WO2010131747A1 (ja) * | 2009-05-15 | 2010-11-18 | 国立大学法人 東京大学 | ウイルス産生細胞 |
| KR101772860B1 (ko) | 2009-06-05 | 2017-08-30 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | T 세포 및 조혈 세포의 재프로그래밍 |
| CN102712903A (zh) * | 2009-06-19 | 2012-10-03 | 索尔克生物学研究院 | 从脐带血产生诱导的多能干细胞 |
| WO2011005580A2 (en) * | 2009-06-23 | 2011-01-13 | The Scripps Research Institute | Adult animals generated from induced pluripotent cells |
| JP5645197B2 (ja) * | 2009-06-23 | 2014-12-24 | 学校法人日本大学 | 幹細胞の未分化状態を維持する新規方法 |
| JP2011004674A (ja) * | 2009-06-26 | 2011-01-13 | Fujitsu Ltd | 誘導多能性幹細胞(iPS細胞)の製造方法 |
| US9388381B2 (en) | 2009-07-09 | 2016-07-12 | Massachusetts Institute Of Technology | Methods and compositions for increased safety of stem cell-derived populations |
| US9550975B2 (en) | 2009-07-15 | 2017-01-24 | Mari Dezawa | SSEA-3 pluripotent stem cell isolated from body tissue |
| WO2011019957A1 (en) * | 2009-08-12 | 2011-02-17 | University Of Southern California | Method for formation of induced pluripotent stem cells |
| EP2468312A4 (en) | 2009-08-19 | 2014-05-14 | Univ Tohoku | FOIL FOR CORNEAL TRANSPLANTS |
| MX2012002117A (es) * | 2009-08-21 | 2012-06-01 | Univ Leland Stanford Junior | Eficiencia mejorada para la generacion de celulas madre pluripotentes inducidas a partir de las celulas somaticas humanas. |
| KR20120061053A (ko) | 2009-08-27 | 2012-06-12 | 시냅틱 리서치, 엘엘씨 | 유도 만능 줄기(iPS) 세포 또는 조직 특이적 세포를 생성하기 위한 신규한 단백질 전달 시스템 |
| WO2011032025A2 (en) * | 2009-09-10 | 2011-03-17 | The Salk Institute For Biological Studies | Adipose-derived induced pluripotent stem cells |
| US20120301438A1 (en) * | 2009-09-14 | 2012-11-29 | The Johns Hopkins University | Reprogramming Blood Cells to Pluripotent and Multipotent Stem Cells |
| US9808504B2 (en) * | 2009-09-22 | 2017-11-07 | Yale University | Immunogenic epitopes as targets for universal cancer vaccines |
| US9422525B2 (en) * | 2009-09-30 | 2016-08-23 | Agency For Science, Technology And Research | Nuclear receptor and mutant thereof and the use of the same in the reprogramming of cells |
| CA3091210C (en) | 2009-10-16 | 2023-04-04 | The Scripps Research Institute | Induction of pluripotent cells |
| US9340772B2 (en) | 2009-10-29 | 2016-05-17 | Mcmaster University | Generating induced pluripotent stem cells and progenitor cells from fibroblasts |
| KR20190065476A (ko) * | 2009-10-30 | 2019-06-11 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 간외 담도계로부터의 다분화능 줄기 세포 및 이의 분리 방법 |
| AU2010315166B2 (en) * | 2009-11-04 | 2015-01-22 | FUJIFILM Cellular Dynamics, Inc. | Episomal reprogramming with chemicals |
| WO2011059920A2 (en) | 2009-11-10 | 2011-05-19 | The J. David Gladstone Institutes | Methods of generating neural stem cells |
| ES2779048T3 (es) | 2009-11-12 | 2020-08-13 | Technion Res & Dev Foundation | Medios de cultivo, cultivos celulares y métodos de cultivo de células madre pluripotentes en un estado indiferenciado |
| US10485829B2 (en) | 2009-11-17 | 2019-11-26 | Astellas Institute For Regenerative Medicine | Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells |
| KR20180086301A (ko) | 2009-12-04 | 2018-07-30 | 스템 셀 앤드 리제너러티브 메디신 인터내셔날, 인크. | 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성 |
| JPWO2011071118A1 (ja) | 2009-12-09 | 2013-04-22 | 国立大学法人京都大学 | ニトロビンを含む多能性幹細胞の心筋細胞への分化促進剤 |
| EP2532741B1 (en) * | 2010-02-03 | 2018-04-04 | Tetsuya Ishikawa | Induced hepatic stem cell and process for production thereof, and applications of the cell |
| WO2011096825A1 (en) * | 2010-02-05 | 2011-08-11 | Auckland Uniservices Limited | Cell programming |
| ES2623859T3 (es) * | 2010-03-04 | 2017-07-12 | Miacom Diagnostics Gmbh | FISH múltiple mejorada |
| CN102190731B (zh) * | 2010-03-09 | 2016-01-27 | 中国科学院上海生命科学研究院 | 用人工转录因子诱导产生多能干细胞 |
| ES2893699T3 (es) | 2010-03-31 | 2022-02-09 | Scripps Research Inst | Reprogramación de células |
| WO2011130624A2 (en) | 2010-04-16 | 2011-10-20 | Immune Disease Institute, Inc. | Sustained polypeptide expression from synthetic, modified rnas and uses thereof |
| US8048675B1 (en) | 2010-05-12 | 2011-11-01 | Ipierian, Inc. | Integration-free human induced pluripotent stem cells from blood |
| DK2568991T6 (en) * | 2010-05-12 | 2019-03-18 | Abt Holding Co | MODULATION OF SPLENOCYTES IN CELL THERAPY |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9089520B2 (en) | 2010-05-21 | 2015-07-28 | Baylor College Of Medicine | Methods for inducing selective apoptosis |
| US20130198876A1 (en) * | 2010-05-25 | 2013-08-01 | National Cancer Center | Induced malignant stem cells or pre-induction cancer stem cells capable of selfreplication outside of an organism, production method for same, and practical application for same |
| SG186144A1 (en) | 2010-06-02 | 2013-01-30 | Agency Science Tech & Res | Method for inducing pluripotency in human somatic cells with prdm14 or nfrkb |
| US9376664B2 (en) | 2010-06-14 | 2016-06-28 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| EP2397851B1 (fr) * | 2010-06-21 | 2015-01-07 | Centre d'Etude des Cellules Souches | Méthode de sélection des modulateurs de la synthèse de mévalonate en utilisant des cellules dérivées de cellules pluripotentes humaines |
| US20120021445A1 (en) * | 2010-06-29 | 2012-01-26 | Hogan Kirk J | Pluripotent Stem Cells for Drug Induced Myopathy and Malignant Hyperthermia |
| JP2012029684A (ja) * | 2010-06-30 | 2012-02-16 | Cell Aid Kenkyusho:Kk | 細胞の製造方法 |
| WO2012012708A1 (en) * | 2010-07-22 | 2012-01-26 | Regents Of The University Of Minnesota | Induced pluripotent stem cells |
| HUE054517T2 (hu) | 2010-07-23 | 2021-09-28 | Astellas Inst For Regenerative Medicine | Eljárások sejtek ritka alpopulációinak detektálására és nagymértékben tisztított sejtkészítmények |
| US9394523B2 (en) | 2010-08-22 | 2016-07-19 | Ramot At Tel-Aviv University Ltd. | Induced pluripotent stem cells derived from human pancreatic beta cells |
| JP5930205B2 (ja) | 2010-08-26 | 2016-06-08 | 国立大学法人京都大学 | 多能性幹細胞の心筋分化促進剤 |
| WO2012027486A2 (en) * | 2010-08-26 | 2012-03-01 | The Regents Of The University Of California | Methods and compositions for generation of induced pluripotent stem cells by rnaa |
| US9499790B2 (en) | 2010-08-26 | 2016-11-22 | Kyoto University | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells |
| US8068011B1 (en) | 2010-08-27 | 2011-11-29 | Q Street, LLC | System and method for interactive user-directed interfacing between handheld devices and RFID media |
| EP2611943B1 (en) | 2010-09-03 | 2017-01-04 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with prostate cancer risk |
| CN103459611B (zh) | 2010-09-17 | 2016-11-02 | 哈佛大学校长及研究员协会 | 对多能干细胞的效用和安全性进行表征的功能基因组学研究 |
| AU2011316830A1 (en) | 2010-10-22 | 2013-05-02 | Biotime Inc. | Methods of modifying transcriptional regulatory networks in stem cells |
| KR20140063501A (ko) | 2010-12-22 | 2014-05-27 | 페이트 세러퓨틱스, 인코포레이티드 | 단세포 분류 및 iPSC의 증강된 재프로그래밍을 위한 세포 배양 플랫폼 |
| EP2659404B1 (en) | 2010-12-29 | 2018-08-08 | Sigma-Aldrich Co., LLC | Cells having disrupted expression of proteins involved in adme and toxicology processes |
| US20120252122A1 (en) * | 2011-01-05 | 2012-10-04 | Sangamo Biosciences, Inc. | Methods and compositions for increasing production of induced pluripotent stem cells (ipscs) |
| US9534256B2 (en) | 2011-01-06 | 2017-01-03 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with risk of aggressive prostate cancer |
| EP2665811B1 (en) | 2011-01-19 | 2017-10-18 | The Regents of The University of California | Somatic cells with innate potential for pluripotency |
| US9228204B2 (en) | 2011-02-14 | 2016-01-05 | University Of Utah Research Foundation | Constructs for making induced pluripotent stem cells |
| WO2012112458A2 (en) * | 2011-02-14 | 2012-08-23 | The Regents Of The University Of California | Compositions and methods for increasing reprogramming efficiency |
| TWI445301B (zh) * | 2011-03-03 | 2014-07-11 | Realtek Semiconductor Corp | 傳送/接收電路以及傳送/接收電路阻抗校正方法 |
| US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
| WO2012159079A1 (en) | 2011-05-18 | 2012-11-22 | The Parkinson's Institute | Assay to determine lrrk2 activity in parkinson's disease |
| WO2012165287A1 (ja) | 2011-05-27 | 2012-12-06 | 公立大学法人横浜市立大学 | 人工癌幹細胞の作製方法及びその分化誘導方法 |
| WO2012174467A2 (en) * | 2011-06-15 | 2012-12-20 | Salk Institute For Biological Studies | Cord blood-derived neurons by expression of sox2 |
| CN103987854A (zh) | 2011-07-21 | 2014-08-13 | 小利兰·斯坦福大学托管委员会 | 来自患者的诱导性多能干细胞的心肌细胞及其使用方法 |
| WO2013014929A1 (en) | 2011-07-25 | 2013-01-31 | Kyoto University | Method for screening induced pluripotent stem cells |
| JP6124347B2 (ja) * | 2011-08-02 | 2017-05-10 | 石川 哲也 | TGF−βシグナリング阻害剤および/またはY−27632による肝前駆細胞の誘導方法および製造方法、並びに当該肝前駆細胞から肝細胞の製造方法 |
| EP2756092A4 (en) * | 2011-09-16 | 2015-10-28 | Giovanni Amabile | METHOD FOR THE PRODUCTION OF CELLS, TISSUE AND ANTIBODIES |
| CN102329769B (zh) * | 2011-09-28 | 2013-07-31 | 浙江大学 | 一种获得造血干细胞的方法 |
| US9670463B2 (en) | 2011-10-14 | 2017-06-06 | Children's Medical Center Corporation | Inhibition and enhancement of reprogramming by chromatin modifying enzymes |
| WO2013058403A1 (ja) | 2011-10-21 | 2013-04-25 | 国立大学法人京都大学 | 層流による多能性維持単一分散細胞培養法 |
| GB2496375A (en) | 2011-10-28 | 2013-05-15 | Kymab Ltd | A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof |
| JP5999658B2 (ja) | 2011-11-25 | 2016-09-28 | 国立大学法人京都大学 | 多能性幹細胞の培養方法 |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| CA2857545A1 (en) | 2011-11-30 | 2013-06-06 | Advanced Cell Technology, Inc. | Mesenchymal stromal cells and uses related thereto |
| WO2013081188A1 (ja) | 2011-11-30 | 2013-06-06 | 独立行政法人国立がん研究センター | 誘導悪性幹細胞 |
| BR112014013152B1 (pt) | 2011-12-01 | 2021-08-31 | New York Stem Cell Foundation, Inc | Sistema automatizado para geração de células-tronco pluripotentes induzidas (ipscs) |
| US10428309B2 (en) | 2011-12-01 | 2019-10-01 | New York Stem Cell Foundation, Inc. | Systems and methods for producing stem cells and differentiated cells |
| GB201122047D0 (en) | 2011-12-21 | 2012-02-01 | Kymab Ltd | Transgenic animals |
| KR20250035015A (ko) | 2011-12-05 | 2025-03-11 | 팩터 바이오사이언스 인크. | 세포를 형질감염시키는 방법들 및 생성물들 |
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| WO2013111875A1 (ja) | 2012-01-27 | 2013-08-01 | 国立大学法人京都大学 | 多能性幹細胞の心筋分化誘導法 |
| WO2013147082A1 (ja) * | 2012-03-28 | 2013-10-03 | 株式会社クオリーメン | 不死化幹細胞及びその産生物を有効成分とする医薬組成物並びに医薬製剤 |
| US9447378B2 (en) | 2012-04-27 | 2016-09-20 | Massachusetts Institute Of Technology | Method for differentiating human embryonic stem cells into β-cells for the treatment of type I diabetes |
| US10155929B2 (en) * | 2012-05-13 | 2018-12-18 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| US10119150B2 (en) * | 2012-05-13 | 2018-11-06 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| GB2537000C (en) | 2012-05-25 | 2019-10-09 | Univ California | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| ES2846789T3 (es) | 2012-07-11 | 2021-07-29 | Tissuetech Inc | Composiciones que contienen complejos HC-HA/PTX3 y métodos de uso de los mismos |
| WO2014011407A2 (en) | 2012-07-12 | 2014-01-16 | Imstem Biotechnology, Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| US9175263B2 (en) * | 2012-08-22 | 2015-11-03 | Biotime, Inc. | Methods and compositions for targeting progenitor cell lines |
| WO2014031085A1 (en) * | 2012-08-24 | 2014-02-27 | Agency For Science, Technology And Research | The use of pdgf-bb in a method of enhancing the efficiency of reprogramming of a somatic cell to a pluripotent stem cell |
| SG11201502497RA (en) * | 2012-10-05 | 2015-04-29 | Cincinnati Children S Hospital Medical Ct | Sebocyte cell culturing and methods of use |
| US20150313947A1 (en) * | 2012-12-03 | 2015-11-05 | Anthrogenesis Corporation | Treatment of schizophrenia using amnion derived adherent cells |
| ES2896354T3 (es) | 2012-12-21 | 2022-02-24 | Astellas Inst For Regenerative Medicine | Métodos para la producción de plaquetas a partir de células madre pluripotentes |
| WO2014102778A2 (en) * | 2012-12-24 | 2014-07-03 | Ramot At Tel-Aviv University Ltd. | Agents for treating genetic diseases resulting from nonsense mutations, and methods for identifying the same |
| JP6433902B2 (ja) * | 2013-01-04 | 2018-12-05 | 国立大学法人京都大学 | 初期化幹細胞 |
| US9709554B2 (en) | 2013-01-31 | 2017-07-18 | Rutgers, The State University Of New Jersey | In vitro model of macrosteatotic (fatty) liver |
| EP2954046B1 (en) | 2013-02-06 | 2025-10-15 | University Of Rochester | Induced pluripotent cell-derived oligodendrocyte progenitor cells for the treatment of myelin disorders |
| EP2953473B1 (en) | 2013-02-06 | 2018-11-28 | Nc Medical Research Inc. | Method of producing a heterogeneous subpopulation of bone marrow cells suitable for the treatement of neurodegeneration cased by ischemic stroke |
| US20160002599A1 (en) | 2013-02-08 | 2016-01-07 | Kyoto University | Production methods for megakaryocytes and platelets |
| US10160950B2 (en) | 2013-03-01 | 2018-12-25 | Wisconsin Alumni Research Foundation | Methods of maintaining, expanding and differentiating neuronal subtype specific progenitors |
| US20140248696A1 (en) * | 2013-03-01 | 2014-09-04 | Wisconsin Alumni Research Foundation | Methods of maintaining, expanding, and diffrentiating neuronal subtype specific progenitors |
| EP2966163B1 (en) | 2013-03-06 | 2018-01-17 | Kyoto University | Culture system for pluripotent stem cells and method for subculturing pluripotent stem cells |
| WO2014136519A1 (ja) | 2013-03-08 | 2014-09-12 | 国立大学法人京都大学 | Egf受容体阻害剤を含む多能性幹細胞の心筋分化促進剤 |
| US9434935B2 (en) | 2013-03-10 | 2016-09-06 | Bellicum Pharmaceuticals, Inc. | Modified caspase polypeptides and uses thereof |
| WO2014143383A1 (en) | 2013-03-13 | 2014-09-18 | Agilent Technologies, Inc. | Transposome tethered to a gene delivery vehicle |
| CA2899507A1 (en) | 2013-03-14 | 2014-09-25 | The Regents Of The University Of California | In vitro production of medial ganglionic eminence precursor cells |
| US20160237400A1 (en) * | 2013-03-15 | 2016-08-18 | The Jackson Laboratory | Isolation of non-embryonic stem cells and uses thereof |
| EP2970913B1 (en) * | 2013-03-15 | 2018-08-22 | LongBoat Explorers AB | Cells, methods and apparatuses for umbilical cord blood collection and isolation of cells |
| US10519421B2 (en) | 2013-03-21 | 2019-12-31 | Kyoto University | Induction of motor neurons from pluripotent stem cells |
| EP2980207B1 (en) | 2013-03-25 | 2018-12-05 | Foundation for Biomedical Research and Innovation at Kobe | Cell sorting method |
| US10961508B2 (en) | 2013-04-12 | 2021-03-30 | Kyoto University | Method for inducing alveolar epithelial progenitor cells |
| US20160082015A1 (en) * | 2013-04-18 | 2016-03-24 | President And Fellows Of Harvard College | Methods, compositions and kits for promoting motor neuron survival and treating and diagnosing neurodegenerative disorders |
| JP6429280B2 (ja) | 2013-05-14 | 2018-11-28 | 国立大学法人京都大学 | 効率的な心筋細胞の誘導方法 |
| EP3006559B1 (en) | 2013-05-31 | 2019-11-06 | iHeart Japan Corporation | Layered cell sheet incorporating hydrogel |
| US10961531B2 (en) | 2013-06-05 | 2021-03-30 | Agex Therapeutics, Inc. | Compositions and methods for induced tissue regeneration in mammalian species |
| CA2912172A1 (en) | 2013-06-05 | 2014-12-11 | Bellicum Pharmaceuticals, Inc. | Methods for inducing partial apoptosis using caspase polypeptides |
| EP3008229B1 (en) | 2013-06-10 | 2020-05-27 | President and Fellows of Harvard College | Early developmental genomic assay for characterizing pluripotent stem cell utility and safety |
| EP3020803B1 (en) | 2013-06-11 | 2020-03-11 | Kyoto University | Method for producing renal precursor cells |
| SG10201710303TA (en) * | 2013-06-12 | 2018-02-27 | Shiseido Co Ltd | Serum-free medium containing pdgf for ds cells |
| US9816070B2 (en) | 2013-06-14 | 2017-11-14 | Massachusetts Institute Of Technology | Articles and methods for stem cell differentiation |
| EP3013941B1 (en) * | 2013-06-27 | 2018-10-31 | New York Stem Cell Foundation, Inc. | Improved systems and methods for producing stem cells and differentiated cells |
| US10738323B2 (en) | 2013-07-12 | 2020-08-11 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
| US20150024406A1 (en) * | 2013-07-17 | 2015-01-22 | Robin N. Coger-Simmons | Increased aquaporin expression on cellular membrane to improve cryopreservation efficiency |
| US20150037436A1 (en) | 2013-07-30 | 2015-02-05 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| JP6378183B2 (ja) | 2013-08-07 | 2018-08-22 | 国立大学法人京都大学 | 膵ホルモン産生細胞の製造法 |
| EP2840132B1 (en) | 2013-08-22 | 2016-11-30 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin | Method for producing Engineered Heart Muscle (EHM) |
| EP3042951B1 (en) | 2013-09-05 | 2019-02-20 | Kyoto University | New method for inducing dopamine-producing neural precursor cells |
| US20160222347A1 (en) | 2013-09-12 | 2016-08-04 | Kaneka Corporation | Method for inducing differentiation of induced pluripotent stem cells and method for selecting the same |
| EP3045451B1 (en) | 2013-09-13 | 2018-03-28 | Kyoto University | Compound promoting differentiation of pluripotent stem cells into cardiomyocytes |
| WO2015040497A2 (en) | 2013-09-20 | 2015-03-26 | Lonza Ltd | Methods for nuclear reprogramming of cells |
| CA2924816C (en) * | 2013-09-20 | 2023-09-05 | Repairon Gmbh | A method to direct differentiation of pluripotent stem cells into functional heart muscle |
| CN104450609B (zh) * | 2013-09-25 | 2017-07-14 | 深圳华大基因科技有限公司 | 一种分离和培养脐带间充质干细胞的方法 |
| WO2015058117A1 (en) * | 2013-10-18 | 2015-04-23 | Icahn School Of Medicine At Mount Sinai | Directed cardiomyocyte differentiation and ventricular specification of stem cells |
| WO2015061568A1 (en) * | 2013-10-23 | 2015-04-30 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Reprogramming cardiomyocytes with one transcription factor |
| WO2015064754A1 (ja) | 2013-11-01 | 2015-05-07 | 国立大学法人京都大学 | 新規軟骨細胞誘導方法 |
| US11767507B2 (en) | 2013-11-08 | 2023-09-26 | The Mclean Hospital Corporation | Methods for efficient generation of GABAergic interneurons from pluripotent stem cells |
| US9932607B2 (en) | 2013-11-15 | 2018-04-03 | The Board Of Trustees Of The Leland Stanford Junior University | Site-specific integration of transgenes into human cells |
| EP3071695A2 (en) | 2013-11-18 | 2016-09-28 | Crispr Therapeutics AG | Crispr-cas system materials and methods |
| WO2015087231A1 (en) | 2013-12-11 | 2015-06-18 | Pfizer Limited | Method for producing retinal pigment epithelial cells |
| EP3080266B1 (en) | 2013-12-12 | 2021-02-03 | The Regents of The University of California | Methods and compositions for modifying a single stranded target nucleic acid |
| US9512406B2 (en) | 2013-12-20 | 2016-12-06 | The J. David Gladstone Institute, a testamentary trust established under the Will of J. David Gladstone | Generating hepatocytes |
| US11078462B2 (en) | 2014-02-18 | 2021-08-03 | ReCyte Therapeutics, Inc. | Perivascular stromal cells from primate pluripotent stem cells |
| ES2966757T3 (es) | 2014-03-04 | 2024-04-24 | Fate Therapeutics Inc | Métodos de reprogramación mejorados y plataformas de cultivo celular |
| KR102443578B1 (ko) * | 2014-03-19 | 2022-09-16 | 브이셀 세라퓨틱스 인코포레이티드 | 다능성 세포에 관한 방법 |
| CA2948975A1 (en) | 2014-05-14 | 2015-11-19 | University Of Limerick | Microfluidic device with channel plates |
| JP6651218B2 (ja) | 2014-05-30 | 2020-02-19 | 国立大学法人京都大学 | 低分子化合物を用いた多能性幹細胞の心筋分化誘導法 |
| EP3786285A1 (en) * | 2014-06-05 | 2021-03-03 | Cedars-Sinai Medical Center | A novel and efficient method for reprogramming immortalized lymphoblastoid cell lines to induced pluripotent stem cells |
| US10240127B2 (en) | 2014-07-03 | 2019-03-26 | ReCyte Therapeutics, Inc. | Exosomes from clonal progenitor cells |
| TWI719939B (zh) | 2014-07-14 | 2021-03-01 | 日商中外製藥股份有限公司 | 鑑定蛋白質抗原決定位之方法 |
| SG11201701191WA (en) | 2014-07-18 | 2017-03-30 | Univ Kyoto | Method for inducing t cells for cell-based immunotherapy from pluripotent stem cells |
| US10570418B2 (en) | 2014-09-02 | 2020-02-25 | The Regents Of The University Of California | Methods and compositions for RNA-directed target DNA modification |
| EP3194571A4 (en) | 2014-09-18 | 2018-04-18 | North Carolina State University | Mammalian lung spheroids and lung spheroid cells and uses thereof |
| WO2016061298A1 (en) * | 2014-10-15 | 2016-04-21 | Coyne Ip Holdings, Llc | Methods for conducting stimulus-response studies with induced pluripotent stem cells derived from perinatal cells or tissues |
| CA2966300C (en) | 2014-11-03 | 2023-07-11 | Mirjam H.M. Heemskerk | T cell receptors directed against bob1 and uses thereof |
| CA2968655C (en) | 2014-11-25 | 2021-11-16 | President And Fellows Of Harvard College | Methods for generation of podocytes from pluripotent stem cells and cells produced by the same |
| WO2016088243A1 (ja) * | 2014-12-05 | 2016-06-09 | 株式会社ニコン | 判定装置、観察システム、観察方法、そのプログラム、細胞の製造方法、および細胞 |
| JP7253692B2 (ja) | 2014-12-26 | 2023-04-07 | 国立大学法人京都大学 | 肝細胞誘導方法 |
| JP7199809B2 (ja) | 2015-02-13 | 2023-01-06 | ファクター バイオサイエンス インコーポレイテッド | 核酸製品及びその投与方法 |
| HK1248270A1 (zh) | 2015-02-17 | 2018-10-12 | 大学健康网路 | 制备和使用窦房结样起搏器心肌细胞和心室样心肌细胞的方法 |
| JP2016202172A (ja) | 2015-04-16 | 2016-12-08 | 国立大学法人京都大学 | 疑似膵島の製造方法 |
| US9724432B2 (en) | 2015-04-30 | 2017-08-08 | University Of Rochester | Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder |
| US10531957B2 (en) | 2015-05-21 | 2020-01-14 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
| RU2725737C2 (ru) * | 2015-05-29 | 2020-07-03 | Регенерон Фармасьютикалс, Инк. | Животные, отличные от человека, с нарушением в локусе c9orf72 |
| US10883086B2 (en) | 2015-07-06 | 2021-01-05 | University Of Georgia Research Foundation, Inc. | Methods and compositions related to increased influenza virus production |
| US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| WO2017027466A1 (en) * | 2015-08-07 | 2017-02-16 | The J. David Gladstone Institutes | Method of determining cellular protein homeostasis |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| CN108138130A (zh) | 2015-08-31 | 2018-06-08 | 爱平世股份有限公司 | 多能干细胞制造系统和生产诱导多能干细胞的方法 |
| WO2017039445A1 (en) | 2015-09-01 | 2017-03-09 | Pluriomics B.V. | An in vitro method of differentiating a human pluripotent stem cell population into a cardiomyocyte cell population |
| JP2018532402A (ja) | 2015-09-24 | 2018-11-08 | クリスパー セラピューティクス アーゲー | Rnaプログラム可能エンドヌクレアーゼの新規のファミリーならびにゲノム編集および他の適用におけるそれらの使用 |
| CN108138140A (zh) * | 2015-10-08 | 2018-06-08 | 高雄医学大学 | 一种快速分离脂肪间质细胞的组合物 |
| SG10202111851YA (en) * | 2015-10-16 | 2021-12-30 | Fate Therapeutics Inc | Platform for the Induction & Maintenance of Ground State Pluripotency |
| JP2018531610A (ja) * | 2015-11-02 | 2018-11-01 | オリジェン, インコーポレイテッド | 細胞周期ブロックは、人工多能性幹細胞の生成効率を改善する |
| AU2016366158B2 (en) | 2015-12-07 | 2023-02-23 | Agex Therapeutics, Inc. | Methods for the re-derivation of diverse pluripotent stem cell-derived brown fat cells |
| WO2017100683A1 (en) * | 2015-12-09 | 2017-06-15 | Stemgenics, Inc. | Differential drug screening using pluripotent stem cells induced with functionalized nanoparticles |
| JOP20200228A1 (ar) | 2015-12-21 | 2017-06-16 | Novartis Ag | تركيبات وطرق لخفض تعبير البروتين tau |
| WO2017120443A1 (en) * | 2016-01-07 | 2017-07-13 | Cedars-Sinai Medical Center | Method to identify key markers of human pluripotent cell-derived somatic cells that predict molecular similarity to in vivo target cells |
| US20190018000A1 (en) | 2016-01-12 | 2019-01-17 | Cedars-Sinai Medical Center | A method of non destructive monitoring of biological processes in microfluidic tissue culture systems |
| AU2017213795A1 (en) | 2016-02-01 | 2018-08-16 | Cedars-Sinai Medical Center | Systems and methods for growth of intestinal cells in microfluidic devices |
| WO2017143071A1 (en) | 2016-02-18 | 2017-08-24 | The Regents Of The University Of California | Methods and compositions for gene editing in stem cells |
| WO2017159862A1 (ja) | 2016-03-18 | 2017-09-21 | 国立大学法人京都大学 | 多能性幹細胞由来心筋細胞の凝集体の凍結方法 |
| US11773375B2 (en) | 2016-03-25 | 2023-10-03 | Ncardia B.V. | In vivo method for differentiating human pluripotent stem cells into atrial cardiomyocytes |
| US11401504B2 (en) | 2016-04-15 | 2022-08-02 | Kyoto University | Method for inducing antigen specific CD8 positive T cells |
| EP3447130A4 (en) | 2016-04-22 | 2019-11-13 | Kyoto University | METHOD FOR PRODUCING DOPAMINE-PROPERING NEURAL PRESERVATOR CELLS |
| US11352605B2 (en) | 2016-05-12 | 2022-06-07 | Erasmus University Medical Center Rotterdam | Method for culturing myogenic cells, cultures obtained therefrom, screening methods, and cell culture medium |
| US11572545B2 (en) | 2016-06-16 | 2023-02-07 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| US10221395B2 (en) | 2016-06-16 | 2019-03-05 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| US20190330603A1 (en) | 2016-06-17 | 2019-10-31 | Genesis Technologies Limited | Crispr-cas system, materials and methods |
| US11103537B2 (en) | 2016-06-23 | 2021-08-31 | Tithon Biotech Inc. | Cells expressing parathyroid hormone 1 receptor and uses thereof |
| RU2771328C2 (ru) * | 2016-06-23 | 2022-04-29 | Титон Биотек, Инк. | Клетки, экспрессирующие рецептор паратиреоидного гормона 1, и их применение |
| EP3500585A4 (en) | 2016-08-17 | 2020-04-01 | Factor Bioscience Inc. | NUCLEIC ACID PRODUCTS AND METHODS OF ADMINISTRATION |
| AU2017342176A1 (en) | 2016-10-10 | 2019-05-02 | The National Institute for Biotechnology in the Negev Ltd. | Non-cytotoxic modified cells and use thereof |
| US11542473B2 (en) | 2016-10-21 | 2023-01-03 | Amniotics Ab | Methods and compositions for generating hematopoietic cells |
| JP7141043B2 (ja) | 2016-12-27 | 2022-09-22 | 住友化学株式会社 | 人工多能性幹細胞の評価方法及び選抜方法、並びに人工多能性幹細胞の製造方法 |
| WO2018135646A1 (ja) | 2017-01-20 | 2018-07-26 | 国立大学法人京都大学 | CD8α+β+細胞傷害性T細胞の製造方法 |
| US11913022B2 (en) | 2017-01-25 | 2024-02-27 | Cedars-Sinai Medical Center | In vitro induction of mammary-like differentiation from human pluripotent stem cells |
| EP3574096A4 (en) * | 2017-01-25 | 2020-11-04 | Whitehead Institute for Biomedical Research | GENOMIC NETWORK CONSTRUCTION PROCESSES AND THEIR USES |
| JP7162537B2 (ja) | 2017-01-26 | 2022-10-28 | 国立大学法人大阪大学 | 幹細胞の中胚葉系細胞への分化誘導用培地および中胚葉系細胞の製造方法 |
| US12440578B2 (en) | 2017-02-22 | 2025-10-14 | Io Biosciences, Inc. | Nucleic acid constructs comprising gene editing multi-sites and uses thereof |
| US10828330B2 (en) | 2017-02-22 | 2020-11-10 | IO Bioscience, Inc. | Nucleic acid constructs comprising gene editing multi-sites and uses thereof |
| JPWO2018159805A1 (ja) | 2017-03-03 | 2020-01-09 | 国立大学法人京都大学 | 膵前駆細胞の製造方法 |
| GB2574988B (en) * | 2017-03-14 | 2022-09-14 | Emulate Inc | Neuromuscular junction: NMJ-on-chip |
| JP7171055B2 (ja) | 2017-03-14 | 2022-11-15 | 国立大学法人京都大学 | 多能性幹細胞からヘルパーt細胞を製造する方法 |
| US11767513B2 (en) | 2017-03-14 | 2023-09-26 | Cedars-Sinai Medical Center | Neuromuscular junction |
| WO2018176001A2 (en) | 2017-03-24 | 2018-09-27 | Cedars-Sinai Medical Center | Methods and compositions for production of fallopian tube epithelium |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| EP3621434A4 (en) | 2017-05-10 | 2021-03-31 | University of Rochester | METHOD OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS |
| JP7161775B2 (ja) | 2017-05-25 | 2022-10-27 | 国立大学法人京都大学 | 中間中胚葉細胞から腎前駆細胞への分化誘導方法、および多能性幹細胞から腎前駆細胞への分化誘導方法 |
| WO2018230588A1 (ja) | 2017-06-14 | 2018-12-20 | 武田薬品工業株式会社 | 細胞封入デバイス |
| JP6758631B2 (ja) | 2017-06-19 | 2020-09-23 | 国立大学法人大阪大学 | 角膜内皮細胞マーカー及びその利用 |
| KR102422175B1 (ko) | 2017-06-19 | 2022-07-18 | 고에키 자이단 호징 고베 이료 산교 도시 스이신 기코 | 만능 줄기 세포의 분화능의 예측 방법 및 이를 위한 시약 |
| NL2019517B1 (en) | 2017-09-08 | 2019-03-19 | Univ Erasmus Med Ct Rotterdam | New therapy for Pompe disease |
| JP7140400B2 (ja) | 2017-10-17 | 2022-09-21 | 国立大学法人京都大学 | 多能性幹細胞から人工神経筋接合部を得る方法 |
| MA50579A (fr) | 2017-11-09 | 2020-09-16 | Crispr Therapeutics Ag | Systèmes crispr/cas ou crispr/cpf1 à auto-inactivation (sin) et leurs utilisations |
| AU2018370029B2 (en) | 2017-11-15 | 2024-11-07 | Vertex Pharmaceuticals Incorporated | Islet cell manufacturing compositions and methods of use |
| KR20200091885A (ko) | 2017-11-30 | 2020-07-31 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 세포의 배양 방법 |
| KR102137884B1 (ko) * | 2017-12-12 | 2020-07-24 | 순천향대학교 산학협력단 | 타우로우루소디옥시콜린산을 포함하는 고효율 세포전환용 배지 첨가제 |
| KR102137883B1 (ko) * | 2017-12-12 | 2020-07-24 | 순천향대학교 산학협력단 | 페닐부틸산나트륨을 포함하는 고효율 세포전환용 배지 첨가제 |
| WO2019118935A1 (en) | 2017-12-14 | 2019-06-20 | Casebia Therapeutics Limited Liability Partnership | Novel rna-programmable endonuclease systems and their use in genome editing and other applications |
| WO2019124540A1 (ja) | 2017-12-22 | 2019-06-27 | 国立大学法人京都大学 | 細胞培養装置、培養液アスピレータ及び細胞培養方法 |
| US20210095258A1 (en) * | 2018-02-22 | 2021-04-01 | Celularity Inc. | Post partum tissue-derived induced pluripotent stem cells and uses thereof |
| TW201945536A (zh) | 2018-03-19 | 2019-12-01 | 國立大學法人京都大學 | 水凝膠膠囊 |
| MA52074A (fr) | 2018-03-19 | 2021-01-27 | Bayer Healthcare Llc | Nouveaux systèmes d'endonucléase à arn programmable et leurs utilisations |
| EP3768823B1 (en) | 2018-03-23 | 2025-12-31 | Cedars-Sinai Medical Center | METHODS FOR USING CELLS FROM PANCREATIC ISLETS |
| KR102209108B1 (ko) * | 2018-03-27 | 2021-01-28 | 국립암센터 | Oct4 기능 저해용 펩티드를 포함하는 줄기세포성 억제용 조성물 |
| EP3778869A4 (en) | 2018-03-30 | 2021-12-08 | Kyoto University | CARDIOMYOCYTE MATURATION PROMOTER |
| US20210054406A1 (en) | 2018-03-30 | 2021-02-25 | Kyoto University | Cell production method |
| EP3778587B1 (en) | 2018-03-30 | 2023-10-04 | Orizuru Therapeutics, Inc. | Heterocyclic compound |
| EP3775161A4 (en) | 2018-04-06 | 2022-04-06 | Cedars-Sinai Medical Center | NEURODEGENERATIVE DISEASE MODELS DERIVED FROM HUMAN PLURIPOTENTIC STEM CELLS ON A MICROFLUIDIC CHIP |
| US11981918B2 (en) | 2018-04-06 | 2024-05-14 | Cedars-Sinai Medical Center | Differentiation technique to generate dopaminergic neurons from induced pluripotent stem cells |
| IL277806B2 (en) | 2018-04-23 | 2025-02-01 | Univ Kyoto | Growth inhibitor |
| US20210254006A1 (en) | 2018-06-06 | 2021-08-19 | Ideaya Biosciences, Inc. | Methods of culturing and/or expanding stem cells and/or lineage committed progenitor cells using lactam compounds |
| TWI833764B (zh) * | 2018-06-14 | 2024-03-01 | 中央研究院 | 產生誘導式少突膠質譜系細胞之方法及使用該等細胞的治療 |
| EP3806861A1 (en) | 2018-06-18 | 2021-04-21 | University of Rochester | Methods of treating schizophrenia and other neuropsychiatric disorders |
| CA3103675A1 (en) | 2018-06-21 | 2019-12-26 | University Of Rochester | Methods of treating or inhibiting onset of huntington's disease |
| US12391739B2 (en) | 2018-07-13 | 2025-08-19 | Kyoto University | Method for producing gamma delta T cells |
| EP3824912A4 (en) | 2018-07-19 | 2022-04-20 | Kyoto University | PLATEFORM CARTILAGE DERIVED FROM PLURIPOTENTS STEM CELLS AND METHODS FOR PRODUCTION OF PLATEFORM CARTILAGE |
| JP7357369B2 (ja) | 2018-07-23 | 2023-10-06 | 国立大学法人京都大学 | 新規腎前駆細胞マーカーおよびそれを利用した腎前駆細胞の濃縮方法 |
| SG11202101098YA (en) | 2018-08-03 | 2021-03-30 | Univ Kyoto | Cell production method |
| AU2019320072A1 (en) | 2018-08-10 | 2021-02-25 | Vertex Pharmaceuticals Incorporated | Stem cell derived islet differentiation |
| US20220145329A1 (en) | 2018-08-10 | 2022-05-12 | Kyoto University | Method for transfection into cardiomyocytes using cationic lipid |
| WO2020032179A1 (ja) | 2018-08-10 | 2020-02-13 | 国立大学法人京都大学 | Cd3陽性細胞の製造方法 |
| EA202190582A1 (ru) | 2018-08-22 | 2021-05-27 | Киото Юниверсити | Способ получения энтеральных нейральных клеток-предшественников |
| EP3845654A4 (en) | 2018-08-31 | 2022-05-11 | Noile-Immune Biotech, Inc. | Car-expressing t cells and car expression vector |
| EP3854869A4 (en) | 2018-09-19 | 2022-09-07 | Takeda Pharmaceutical Company Limited | INSULIN-PRODUCING CELLS |
| JP7553918B2 (ja) | 2018-10-15 | 2024-09-19 | 公立大学法人横浜市立大学 | 栄養組成物 |
| JP7564102B2 (ja) | 2018-11-28 | 2024-10-08 | クリスパー セラピューティクス アクチェンゲゼルシャフト | LNPでの使用に最適化された、CAS9をコードするmRNA |
| WO2020116606A1 (ja) | 2018-12-06 | 2020-06-11 | キリンホールディングス株式会社 | T細胞又はnk細胞の製造方法、t細胞又はnk細胞の培養用培地、t細胞又はnk細胞の培養方法、未分化t細胞の未分化状態を維持する方法及びt細胞又はnk細胞の増殖促進剤 |
| EP3894556A1 (en) | 2018-12-11 | 2021-10-20 | University of Rochester | Methods of treating schizophrenia and other neuropsychiatric disorders |
| CA3120799A1 (en) | 2018-12-20 | 2020-06-25 | Regeneron Pharmaceuticals, Inc. | Nuclease-mediated repeat expansion |
| US20220076839A1 (en) * | 2018-12-21 | 2022-03-10 | I Peace, Inc. | Health risk information management device, health risk information management method, and program |
| EP3900787A4 (en) | 2018-12-21 | 2022-02-23 | Kyoto University | LUBRICIN-LOCALIZED CARTILE-LIKE TISSUE, METHOD OF MANUFACTURE THEREOF AND COMPOSITION THEREOF FOR TREATMENT OF ARTICULATE-CARTILAGE DEFECTS |
| US20220062341A1 (en) | 2018-12-26 | 2022-03-03 | Kirin Holdings Kabushiki Kaisha | Modified tcr and production method therefor |
| EP3904374A4 (en) | 2018-12-27 | 2022-09-21 | Kyoto University | OBJECT MODIFIED BY A T LYMPHOCYTE RECEPTOR |
| JP7508045B2 (ja) | 2019-02-01 | 2024-07-01 | 国立大学法人京都大学 | 細胞の検出方法 |
| WO2020167822A2 (en) | 2019-02-13 | 2020-08-20 | University Of Rochester | Gene networks that mediate remyelination of the human brain |
| WO2020181101A1 (en) | 2019-03-07 | 2020-09-10 | The Regents Of The University Of California | Crispr-cas effector polypeptides and methods of use thereof |
| WO2020209959A1 (en) | 2019-03-08 | 2020-10-15 | Crispr Therapeutics Ag | Nucleobase-editing fusion protein systems, compositions, and uses thereof |
| MA55297A (fr) | 2019-03-12 | 2022-01-19 | Bayer Healthcare Llc | Nouveaux systèmes d'endonucléase à arn programmable haute fidélité et leurs utilisations |
| CN113748213A (zh) | 2019-03-29 | 2021-12-03 | 公立大学法人横滨市立大学 | 筛选方法及毒性评价方法 |
| US12268715B2 (en) | 2019-04-10 | 2025-04-08 | Orizuru Therapeutics, Inc. | Method for producing biological tissue-like structure |
| EP3962503A4 (en) * | 2019-04-27 | 2022-12-21 | Figene, LLC | SELECTION OF FIBROBLAST DONORS FOR THE OPTIMIZATION OF REGENERATION INDUCED BY ALLOGENIC FIBROBLASTS |
| WO2020225606A1 (en) | 2019-05-08 | 2020-11-12 | Crispr Therapeutics Ag | Crispr/cas all-in-two vector systems for treatment of dmd |
| JPWO2020235319A1 (enExample) | 2019-05-20 | 2020-11-26 | ||
| WO2020236696A1 (en) | 2019-05-23 | 2020-11-26 | Dignity Health | Inhibitory interneuron treatment methods, uses and compositions for diabetes |
| JP7541700B2 (ja) | 2019-06-11 | 2024-08-29 | 国立大学法人京都大学 | 腎間質細胞の製造方法 |
| EP3986358A4 (en) | 2019-06-20 | 2023-06-21 | Amniotics AB | DEVICE FOR FILTERING FRUIT WATER |
| WO2020264072A1 (en) | 2019-06-25 | 2020-12-30 | Semma Therapeutics, Inc. | Enhanced differentiation of beta cells |
| CN114450265B (zh) | 2019-07-03 | 2024-12-24 | 菲克特生物科学股份有限公司 | 阳离子脂质及其用途 |
| CN110257334A (zh) * | 2019-07-24 | 2019-09-20 | 安徽科门生物科技有限公司 | 一种神经干细胞培养基以及培养方法 |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| WO2021030424A1 (en) | 2019-08-13 | 2021-02-18 | Semma Therapeutics, Inc. | Pancreatic differentiation |
| AU2020332643A1 (en) | 2019-08-20 | 2022-03-10 | Orizuru Therapeutics, Inc. | Method for enriching cardiac myocytes |
| AU2020368845A1 (en) | 2019-10-18 | 2022-05-12 | Amniotics Ab | Processes and apparatuses for obtaining amniotic mesenchymal stem cells from amniotic fluid and cells derived thereof |
| CA3158631A1 (en) | 2019-10-21 | 2021-04-29 | Orizuru Therapeutics, Inc. | Growth inhibitor |
| TWI769410B (zh) * | 2019-10-28 | 2022-07-01 | 中國醫藥大學 | 新穎誘導性多能幹細胞(ipscs)及其應用 |
| US11760980B2 (en) | 2019-10-28 | 2023-09-19 | China Medical University | Induced pluripotent stem cells (IPSCS) and applications thereof |
| WO2021085576A1 (ja) | 2019-11-01 | 2021-05-06 | 国立大学法人京都大学 | T細胞の製造方法 |
| AR120538A1 (es) | 2019-11-25 | 2022-02-23 | Univ Kyoto | Banco de células maestras de células t |
| US20230030814A1 (en) | 2019-12-12 | 2023-02-02 | National University Corporation Chiba University | Freeze-Dried Preparations Comprising Megakaryocytes and Platelets |
| WO2021127594A1 (en) * | 2019-12-18 | 2021-06-24 | Editas Medicine, Inc. | Engineered cells for therapy |
| EP4087914A1 (en) | 2020-01-09 | 2022-11-16 | Herophilus, Inc. | Methods and compositions of pro-organ formation on particle substrates and uses thereof |
| EP4103045A4 (en) * | 2020-02-16 | 2024-08-14 | Genetikaplus Ltd. | Methods of therapeutic prognostication |
| MX2022010521A (es) | 2020-02-28 | 2022-09-19 | Takeda Pharmaceuticals Co | Metodo para producir linfocitos citoliticos naturales a partir de celulas madre pluripotentes. |
| EP4123015A4 (en) | 2020-03-19 | 2024-05-22 | Orizuru Therapeutics, Inc. | Cardiomyocyte purification method |
| WO2021187602A1 (ja) | 2020-03-19 | 2021-09-23 | 国立大学法人京都大学 | 心筋細胞の精製方法 |
| TW202204609A (zh) | 2020-03-31 | 2022-02-01 | 國立大學法人京都大學 | T前驅細胞的製造方法 |
| TW202204607A (zh) * | 2020-04-16 | 2022-02-01 | 英商羅斯林科技有限公司 | 誘導性多功能幹細胞(iPSC)之誘導 |
| JP7742651B2 (ja) | 2020-05-26 | 2025-09-22 | 株式会社ヘリオス | 低免疫原性細胞 |
| US20230227787A1 (en) | 2020-05-28 | 2023-07-20 | Orizuru Therapeutics, Inc. | Mass production method of uniform size cell aggregates |
| EP3922431A1 (en) | 2020-06-08 | 2021-12-15 | Erasmus University Medical Center Rotterdam | Method of manufacturing microdevices for lab-on-chip applications |
| US20230235319A1 (en) | 2020-06-12 | 2023-07-27 | Bayer Aktiengesellschaft | Crispr-cas12a directed random mutagenesis agents and methods |
| EP4170020A4 (en) | 2020-06-17 | 2025-01-22 | Kyoto University | IMMUNOCOMPETENT CELLS WITH CHIMERIC ANTIGEN RECEPTOR EXPRESSION |
| JP7429294B2 (ja) | 2020-07-13 | 2024-02-07 | 国立大学法人京都大学 | 骨格筋前駆細胞及びその精製方法、筋原性疾患を治療するための組成物、並びに骨格筋前駆細胞を含む細胞群の製造方法 |
| WO2022019152A1 (ja) | 2020-07-20 | 2022-01-27 | 学校法人 愛知医科大学 | 多能性細胞の未分化維持培養用組成物、多能性細胞の未分化維持培養用培地、多能性細胞の未分化状態での維持培養方法、および多能性細胞の製造方法 |
| WO2022026932A2 (en) | 2020-07-31 | 2022-02-03 | Vertex Pharmaceuticals Incorporated | Differentiation of pancreatic endocrine cells |
| WO2022039279A1 (ja) | 2020-08-18 | 2022-02-24 | 国立大学法人京都大学 | ヒト始原生殖細胞/ヒト始原生殖細胞様細胞の維持増幅方法 |
| US12435308B2 (en) | 2020-11-06 | 2025-10-07 | Amniotics Ab | Immunomodulation by amniotic fluid mesenchymal stem cells |
| JPWO2022107877A1 (enExample) | 2020-11-20 | 2022-05-27 | ||
| CN114763534B (zh) * | 2021-01-13 | 2024-04-26 | 合肥中科普瑞昇生物医药科技有限公司 | 原代胃肠间质瘤细胞培养基、培养方法及其应用 |
| AU2022219794A1 (en) | 2021-02-09 | 2023-08-17 | Orizuru Therapeutics, Inc. | Maturation agent |
| USD969942S1 (en) * | 2021-03-03 | 2022-11-15 | Amber Puchlov | Exercise device |
| CN116964193A (zh) | 2021-03-09 | 2023-10-27 | 国立大学法人东京医科齿科大学 | 细胞簇的制造方法 |
| EP4310176A4 (en) | 2021-03-17 | 2025-03-26 | Astellas Pharma Inc. | Pericyte with basic fibroblast growth factor (BFGF) gene inserted into it |
| CN113106059B (zh) * | 2021-04-07 | 2023-08-15 | 清华大学深圳国际研究生院 | 一种高迁徙间充质干细胞及其制备方法和应用 |
| CN117136231A (zh) | 2021-04-08 | 2023-11-28 | 武田药品工业株式会社 | 用于激活t细胞的方法 |
| WO2022230919A1 (ja) | 2021-04-28 | 2022-11-03 | 国立大学法人 東京医科歯科大学 | 細胞の製造方法 |
| CA3218400A1 (en) | 2021-04-30 | 2022-11-03 | Riken | Cord-like aggregates of retinal pigment epithelial cells, device and production method for producing same, and therapeutic agent comprising said cord-like aggregates |
| US20240252545A1 (en) | 2021-05-07 | 2024-08-01 | Children's Hospital Los Angeles | Methods for Making Stem Cell-Derived Enteric Neural Crest Cells and Their Use in Enteric Neuropathy Treatment |
| WO2022250631A2 (en) * | 2021-05-25 | 2022-12-01 | T.C. Ankara Universitesi Rektorlugu | Disease model of induced pluripotent stem cell (ipsc)-derived type 2 diabetes mellitus, associated with coronary artery disease |
| US20240254441A1 (en) | 2021-06-04 | 2024-08-01 | Kirin Holdings Kabushiki Kaisha | Cell composition, method for producing cell composition, and pharmaceutical composition containing cell composition |
| JPWO2022259721A1 (enExample) | 2021-06-10 | 2022-12-15 | ||
| EP4352214A1 (en) | 2021-06-11 | 2024-04-17 | Bayer AG | Type v rna programmable endonuclease systems |
| EP4101928A1 (en) | 2021-06-11 | 2022-12-14 | Bayer AG | Type v rna programmable endonuclease systems |
| AR126145A1 (es) | 2021-06-15 | 2023-09-13 | Takeda Pharmaceuticals Co | Método para producir linfocitos citolíticos naturales a partir de células madre pluripotentes |
| EP4372080A4 (en) | 2021-07-15 | 2025-08-13 | Astellas Pharma Inc | PERICYTE-LIKE CELL EXPRESSING VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) AT A HIGH LEVEL |
| JPWO2023286832A1 (enExample) | 2021-07-15 | 2023-01-19 | ||
| US20250084373A1 (en) | 2021-07-21 | 2025-03-13 | Kyoto University | Method of producing retinal tissue |
| JPWO2023017848A1 (enExample) | 2021-08-11 | 2023-02-16 | ||
| EP4144841A1 (en) | 2021-09-07 | 2023-03-08 | Bayer AG | Novel small rna programmable endonuclease systems with impoved pam specificity and uses thereof |
| US20240400993A1 (en) | 2021-09-27 | 2024-12-05 | Kyoto University | Method for producing t cell |
| WO2023069843A1 (en) | 2021-10-20 | 2023-04-27 | University Of Rochester | Humanized chimeras for the prospective assessment of cell addition and replacement therapies |
| JP2024539140A (ja) | 2021-10-20 | 2024-10-28 | ユニヴァーシティ オヴ ロチェスター | グリア前駆細胞を若返らせるための方法及び若返ったグリア前駆細胞それ自体 |
| AU2022368907A1 (en) | 2021-10-20 | 2024-05-02 | University Of Copenhagen | Rejuvenation treatment of age-related white matter loss |
| JP2024540987A (ja) | 2021-10-21 | 2024-11-06 | バーテックス ファーマシューティカルズ インコーポレイテッド | 低免疫細胞 |
| EP4426814A2 (en) | 2021-11-01 | 2024-09-11 | Vertex Pharmaceuticals Incorporated | Stem cell derived pancreatic islet differentiation |
| JP2024542015A (ja) | 2021-11-02 | 2024-11-13 | ユニバーシティ オブ ロチェスター | 脳内でのtcf7l2媒介性髄鞘再生 |
| US20250041418A1 (en) | 2021-11-11 | 2025-02-06 | Healios K.K. | Gene-modified pluripotent stem cell, immunocompetent cell derived therefrom, method for producing said cells, and use thereof |
| WO2023118068A1 (en) | 2021-12-23 | 2023-06-29 | Bayer Aktiengesellschaft | Novel small type v rna programmable endonuclease systems |
| WO2023150557A1 (en) | 2022-02-01 | 2023-08-10 | University Of Rochester | Methods of generating a population of neurons from human glial progenitor cells and genetic constructs for carrying out such methods |
| WO2023149555A1 (ja) | 2022-02-04 | 2023-08-10 | 国立大学法人京都大学 | T細胞の製造方法 |
| US20250145948A1 (en) | 2022-02-09 | 2025-05-08 | Sumitomo Pharma Co., Ltd. | Method for assessing differentiation potential of cells in culture broth in differentiation of pluripotent stem cells into neural cells of midbrain floor plate region |
| EP4486358A1 (en) | 2022-03-02 | 2025-01-08 | Lineage Cell Therapeutics, Inc. | Methods and compositions for treating hearing loss |
| CN119256076A (zh) | 2022-03-23 | 2025-01-03 | 国立大学法人京都大学 | 用于产生调节性t细胞的方法 |
| AU2023260469A1 (en) | 2022-04-25 | 2024-11-14 | Cell Cure Neurosciences, Ltd. | Methods and compositions for treating vision loss |
| AU2023262842A1 (en) | 2022-04-25 | 2024-09-12 | Orizuru Therapeutics, Inc. | Maturing agent having both of alk5 inhibitory activity and cdk8/19 inhibitory activity |
| US20250290076A1 (en) | 2022-04-27 | 2025-09-18 | Kyoto University | Epicardial cell regeneration promoter and method for promoting epicardial cell regeneration |
| EP4518876A1 (en) | 2022-05-05 | 2025-03-12 | University of Rochester | Dual macroglial-microglial approach towards therapeutic cell replacement in neurodegenerative and neuropsychiatric disease |
| US20250376727A1 (en) | 2022-06-10 | 2025-12-11 | Kyoto University | Detection method and detection reagent for undifferentiated pluripotent stem cells |
| IL316824A (en) | 2022-06-10 | 2025-01-01 | Bayer Ag | Novel small, programmable endonuclease systems for type V RNA |
| JPWO2023243627A1 (enExample) | 2022-06-17 | 2023-12-21 | ||
| EP4544025A1 (en) | 2022-06-21 | 2025-04-30 | Institut National de la Santé et de la Recherche Médicale | A method for producing a bioengineered mammal induced pluripotent stem cell-derived cardiac organoid |
| KR20250036837A (ko) | 2022-07-14 | 2025-03-14 | 오리즈루 세라퓨틱스 가부시키가이샤 | 세포 이식용의 피브린 겔 시트 |
| CN119698464A (zh) | 2022-07-25 | 2025-03-25 | 国立大学法人京都大学 | 从灵长类的胚胎卵巢细胞诱导卵泡的体外培养法 |
| EP4563703A4 (en) | 2022-07-26 | 2025-09-24 | Univ Kyoto | ARTIFICIAL RECEIVER HAVING A LOAD-SHEDDING STRUCTURE |
| CN120051562A (zh) | 2022-08-05 | 2025-05-27 | 国立大学法人京都大学 | 用于产生心肌的方法 |
| JPWO2024034559A1 (enExample) | 2022-08-08 | 2024-02-15 | ||
| AU2023353929A1 (en) | 2022-09-26 | 2025-05-01 | Kyoto University | T cell production method |
| WO2024070494A1 (ja) | 2022-09-26 | 2024-04-04 | 国立大学法人京都大学 | 膵内胚葉細胞の製造方法 |
| WO2024071280A1 (ja) | 2022-09-29 | 2024-04-04 | 国立大学法人京都大学 | 腎毒性評価方法 |
| CN120302984A (zh) | 2022-11-16 | 2025-07-11 | 学校法人关西医科大学 | 着床促进药和其筛选系统 |
| CN120752335A (zh) | 2022-12-13 | 2025-10-03 | 拜耳公司 | 工程化v型rna可编程核酸内切酶及其用途 |
| JPWO2024157929A1 (enExample) | 2023-01-23 | 2024-08-02 | ||
| EP4658294A2 (en) | 2023-02-02 | 2025-12-10 | University of Rochester | Competitive replacement of glial cells |
| CN120641566A (zh) | 2023-02-06 | 2025-09-12 | 蓝岩治疗有限公司 | 降解决定子融合蛋白及其产生方法和用途 |
| KR20250162771A (ko) * | 2023-03-14 | 2025-11-19 | 세키스이가가쿠 고교가부시키가이샤 | 인공 다능성 줄기 세포의 제조 방법 |
| WO2024248017A1 (ja) | 2023-05-29 | 2024-12-05 | 国立研究開発法人理化学研究所 | 心筋細胞を成熟させる方法及び成熟した心筋細胞の製造方法 |
| WO2024256530A1 (en) | 2023-06-13 | 2024-12-19 | Universiteit Maastricht | Improved method for generating kidney organoids |
| WO2025038494A1 (en) | 2023-08-11 | 2025-02-20 | Tune Therapeutics, Inc. | Compositions, systems, and methods for lymphoid cell differentiation using targeted gene activation |
| WO2025059073A1 (en) | 2023-09-11 | 2025-03-20 | Tune Therapeutics, Inc. | Epigenetic editing methods and systems for differentiating stem cells |
| TW202521691A (zh) | 2023-10-06 | 2025-06-01 | 美商藍岩醫療公司 | 經工程化之v型rna可程式核酸內切酶及其用途 |
| WO2025114599A1 (en) | 2023-12-01 | 2025-06-05 | Academisch Ziekenhuis Maastricht | Improved kidney organoid culture method by modulating pka |
| WO2025117331A1 (en) | 2023-12-01 | 2025-06-05 | Eli Lilly And Company | Methods of making stem cell-derived islet-like cells, as well as populations and compositions including the same |
| WO2025126208A1 (en) | 2023-12-12 | 2025-06-19 | Accellta Ltd. | Media for maintaining, differentiating, or both, pluripotent stem cells |
| WO2025166063A1 (en) | 2024-01-31 | 2025-08-07 | Bluerock Therapeutics Lp | Igfbp2 in cell culture |
| WO2025207481A1 (en) | 2024-03-25 | 2025-10-02 | Bluerock Therapeutics Lp | Measuring viability in cell aggregates |
| WO2025260068A1 (en) | 2024-06-14 | 2025-12-18 | Tune Therapeutics, Inc. | Lipid nanoparticle formulation for delivery of nucleic acids to cells |
Family Cites Families (170)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR901228A (fr) | 1943-01-16 | 1945-07-20 | Deutsche Edelstahlwerke Ag | Système d'aimant à entrefer annulaire |
| US4650764A (en) * | 1983-04-12 | 1987-03-17 | Wisconsin Alumni Research Foundation | Helper cell |
| US4861719A (en) * | 1986-04-25 | 1989-08-29 | Fred Hutchinson Cancer Research Center | DNA constructs for retrovirus packaging cell lines |
| US4864719A (en) * | 1987-04-24 | 1989-09-12 | Amp Incorporated | Tool for removing electrical contacts |
| US4937190A (en) * | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
| US5192553A (en) * | 1987-11-12 | 1993-03-09 | Biocyte Corporation | Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use |
| US6140111A (en) * | 1987-12-11 | 2000-10-31 | Whitehead Institute For Biomedical Research | Retroviral gene therapy vectors and therapeutic methods based thereon |
| US5591624A (en) * | 1988-03-21 | 1997-01-07 | Chiron Viagene, Inc. | Retroviral packaging cell lines |
| US7070994B2 (en) * | 1988-03-21 | 2006-07-04 | Oxford Biomedica (Uk) Ltd. | Packaging cells |
| JP2886547B2 (ja) | 1988-07-26 | 1999-04-26 | 協和醗酵工業株式会社 | ノイラミニダーゼの製造法 |
| WO1990002806A1 (en) * | 1988-09-01 | 1990-03-22 | Whitehead Institute For Biomedical Research | Recombinant retroviruses with amphotropic and ecotropic host ranges |
| JP2928287B2 (ja) | 1988-09-29 | 1999-08-03 | 協和醗酵工業株式会社 | 新規ポリペプチド |
| US5266491A (en) * | 1989-03-14 | 1993-11-30 | Mochida Pharmaceutical Co., Ltd. | DNA fragment and expression plasmid containing the DNA fragment |
| JP3051411B2 (ja) * | 1989-03-14 | 2000-06-12 | 持田製薬株式会社 | 新規dnaならびにそれを含有する発現プラスミド |
| JP2897295B2 (ja) * | 1989-12-14 | 1999-05-31 | 味の素株式会社 | レトロウィルス高生産用dna構築物及びレトロウィルス高生産用細胞株 |
| US5674980A (en) * | 1989-12-21 | 1997-10-07 | Biogen Inc | Fusion protein comprising tat-derived transport moiety |
| US5817491A (en) * | 1990-09-21 | 1998-10-06 | The Regents Of The University Of California | VSV G pseusdotyped retroviral vectors |
| US5288514A (en) * | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
| US5834256A (en) * | 1993-06-11 | 1998-11-10 | Cell Genesys, Inc. | Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells |
| FR2707091B1 (fr) | 1993-06-30 | 1997-04-04 | Cohen Haguenauer Odile | Vecteur rétroviral pour le transfert et l'expression de gènes dans des cellules eucaryotes. |
| US5534423A (en) | 1993-10-08 | 1996-07-09 | Regents Of The University Of Michigan | Methods of increasing rates of infection by directing motion of vectors |
| US5519134A (en) * | 1994-01-11 | 1996-05-21 | Isis Pharmaceuticals, Inc. | Pyrrolidine-containing monomers and oligomers |
| US6013517A (en) * | 1994-05-09 | 2000-01-11 | Chiron Corporation | Crossless retroviral vectors |
| US5525735A (en) * | 1994-06-22 | 1996-06-11 | Affymax Technologies Nv | Methods for synthesizing diverse collections of pyrrolidine compounds |
| US5549974A (en) * | 1994-06-23 | 1996-08-27 | Affymax Technologies Nv | Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof |
| JP4216350B2 (ja) | 1994-09-19 | 2009-01-28 | 大日本住友製薬株式会社 | 動物細胞感染用の組換えdnaウイルスベクター |
| EP0787200B1 (en) * | 1994-10-28 | 2005-04-20 | The Trustees Of The University Of Pennsylvania | Improved adenovirus and methods of use thereof |
| US5843780A (en) * | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US5637456A (en) * | 1995-02-17 | 1997-06-10 | The University Of Texas, Board Of Regents | Rapid test for determining the amount of functionally inactive gene in a gene therapy vector preparation |
| US5707618A (en) * | 1995-03-24 | 1998-01-13 | Genzyme Corporation | Adenovirus vectors for gene therapy |
| US5830725A (en) * | 1995-04-28 | 1998-11-03 | The Board Of Trustees For The Leland Stanford Junior University | Rapid, stable high-titre production of recombing retrovirus |
| US5744320A (en) * | 1995-06-07 | 1998-04-28 | Promega Corporation | Quenching reagents and assays for enzyme-mediated luminescence |
| AU705563B2 (en) | 1995-07-28 | 1999-05-27 | Marie Curie Cancer Care | Transport proteins and their uses |
| JPH11514857A (ja) | 1995-09-20 | 1999-12-21 | メルク エンド カンパニー インコーポレーテッド | 抗原虫剤の標的としてのヒストンデアセチラーゼ |
| DE69611102T2 (de) | 1995-09-22 | 2001-06-21 | Amersham Pharmacia Biotech Uk Ltd., Little Chalfont | Verstärkung der mutagenese von nukleinsäuren |
| US5910434A (en) * | 1995-12-15 | 1999-06-08 | Systemix, Inc. | Method for obtaining retroviral packaging cell lines producing high transducing efficiency retroviral supernatant |
| FR2751345B1 (fr) * | 1996-07-16 | 1998-09-18 | Univ Paris Curie | Lignees d'encapsidation hautement productrices |
| US6255071B1 (en) * | 1996-09-20 | 2001-07-03 | Cold Spring Harbor Laboratory | Mammalian viral vectors and their uses |
| US6025192A (en) * | 1996-09-20 | 2000-02-15 | Cold Spring Harbor Laboratory | Modified retroviral vectors |
| US6017735A (en) * | 1997-01-23 | 2000-01-25 | Marie Curie Cancer Care | Materials and methods for intracellular transport and their uses |
| US6416959B1 (en) * | 1997-02-27 | 2002-07-09 | Kenneth Giuliano | System for cell-based screening |
| ID23855A (id) | 1997-04-16 | 2000-05-25 | Amgen Inc | Protein pengikat osteoprotegerin dan reseptor |
| US6387673B1 (en) | 1997-05-01 | 2002-05-14 | The Salk Institute For Biological Studies | Compounds useful for the modulation of processes mediated by nuclear hormone receptors, methods for the identification and use of such compounds |
| WO1999010536A1 (en) * | 1997-08-22 | 1999-03-04 | Yale University | A process to study changes in gene expression in granulocytic cells |
| US6835567B1 (en) | 1998-04-14 | 2004-12-28 | Signal Pharmaceuticals, Inc. | PNS cell lines and methods of use therefor |
| US20020174013A1 (en) | 1998-04-17 | 2002-11-21 | Viztec Inc., A Florida Corporation | Chip card advertising method and system |
| GB9809178D0 (en) | 1998-04-29 | 1998-07-01 | Univ Edinburgh | Nuclear reprogramming of somatic cells |
| EP1080218A1 (en) | 1998-05-27 | 2001-03-07 | University of Florida | Method of preparing recombinant adeno-associated virus compositions by using an iodixanol gradient |
| FR2779445B1 (fr) | 1998-06-08 | 2000-08-11 | Univ Nantes | Kit d'encapsidation |
| KR20000006334A (ko) * | 1998-06-26 | 2000-01-25 | 이선경 | 바이러스코딩염기서열이전혀없는고효율레트로바이러스벡터 |
| AUPP505798A0 (en) | 1998-08-04 | 1998-08-27 | Fujisawa Pharmaceutical Co., Ltd. | Novel compound fr225497 substance |
| BR9914465A (pt) | 1998-09-29 | 2001-10-09 | Gamida Cell Ltd | Métodos para controlar a proliferação e a diferenciação de células-tronco e células progenitoras e uma composição farmacêutica para induzir a diferenciação em uma população de células |
| US6485959B1 (en) | 1998-10-07 | 2002-11-26 | Cedars Sinai Medical Center | Cell preconditioning and cryopresevation medium |
| AU6339399A (en) * | 1998-10-16 | 2000-05-08 | Novartis Ag | Promotion of self-renewal and improved gene transduction of hematopoietic stem cells by histone deacetylase inhibitors |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| WO2000027995A1 (en) | 1998-11-09 | 2000-05-18 | Monash University | Embryonic stem cells |
| US6376246B1 (en) * | 1999-02-05 | 2002-04-23 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
| US6153432A (en) | 1999-01-29 | 2000-11-28 | Zen-Bio, Inc | Methods for the differentiation of human preadipocytes into adipocytes |
| US6312949B1 (en) | 1999-03-26 | 2001-11-06 | The Salk Institute For Biological Studies | Regulation of tyrosine hydroxylase expression |
| US6773920B1 (en) * | 1999-03-31 | 2004-08-10 | Invitrogen Corporation | Delivery of functional protein sequences by translocating polypeptides |
| EP1186655B1 (en) | 1999-06-01 | 2008-04-09 | Chugai Seiyaku Kabushiki Kaisha | Packaging cell |
| US7015037B1 (en) * | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
| WO2001015511A2 (en) * | 1999-09-01 | 2001-03-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, dna and viruses |
| EP1218489B1 (en) | 1999-09-24 | 2009-03-18 | Cybios LLC | Pluripotent embryonic-like stem cells, compositions, methods and uses thereof |
| US20030161817A1 (en) * | 2001-03-28 | 2003-08-28 | Young Henry E. | Pluripotent embryonic-like stem cells, compositions, methods and uses thereof |
| US6280718B1 (en) | 1999-11-08 | 2001-08-28 | Wisconsin Alumni Reasearch Foundation | Hematopoietic differentiation of human pluripotent embryonic stem cells |
| US7544509B2 (en) * | 2000-01-24 | 2009-06-09 | Mcgill University | Method for preparing stem cell preparations |
| US6395546B1 (en) * | 2000-02-01 | 2002-05-28 | Neurogeneration, Inc. | Generation of dopaminergic neurons from human nervous system stem cells |
| US7439064B2 (en) * | 2000-03-09 | 2008-10-21 | Wicell Research Institute, Inc. | Cultivation of human embryonic stem cells in the absence of feeder cells or without conditioned medium |
| US6458589B1 (en) | 2000-04-27 | 2002-10-01 | Geron Corporation | Hepatocyte lineage cells derived from pluripotent stem cells |
| US20020009743A1 (en) | 2000-05-17 | 2002-01-24 | Carpenter Melissa K. | Neural progenitor cell populations |
| AU6842001A (en) * | 2000-06-15 | 2001-12-24 | Tanja Dominko | Pluripotent mammalian cells |
| DE10031179A1 (de) | 2000-06-27 | 2002-01-31 | Amaxa Gmbh | Verfahren zur Einbringung von Nukleinsäuren und anderen biologisch aktiven Molekülen in den Kern höherer eukaryontischer Zellen mit Hilfe elektrischen Stroms |
| AU2001280767A1 (en) * | 2000-07-31 | 2002-02-13 | Active Motif | Peptide-mediated delivery of molecules into cells |
| JP2002065261A (ja) | 2000-08-30 | 2002-03-05 | Mitsubishi Kasei Institute Of Life Sciences | 生殖細胞の取得方法 |
| ATE324321T1 (de) * | 2000-08-31 | 2006-05-15 | Edwin Lundgren | Steuervorrichtung für einen lenkdrachen an einem boot |
| CA2430653A1 (en) | 2000-11-27 | 2002-08-08 | Yissum Research Development Company Of The Hebrew University In Jerusalem | Transfection of human embryonic stem cells |
| US20080268054A1 (en) | 2000-12-04 | 2008-10-30 | Eugene Bell | Dermal derived human stem cells and compositions and methods thereof |
| US20020142397A1 (en) | 2000-12-22 | 2002-10-03 | Philippe Collas | Methods for altering cell fate |
| IL156746A0 (en) * | 2001-01-02 | 2004-02-08 | Stemron Inc | A method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom and materials and method using same |
| JP2003009854A (ja) | 2001-04-09 | 2003-01-14 | Kyowa Hakko Kogyo Co Ltd | エンブリオイドボディ形成方法及びその用途 |
| DE10291734D2 (de) | 2001-04-23 | 2004-05-27 | Lorbach Elke | Pufferlösung für die Elektroporation und Verfahren umfassend die Verwendung derselben |
| DE10119901A1 (de) | 2001-04-23 | 2002-10-24 | Amaxa Gmbh | Schaltungsanordnung zur Einbringung von Nukleinsäuren und anderen biologisch aktiven Molekülen in den Kern höherer eukaryontischer Zellen mit Hilfe elektrischen Stroms |
| JP4183614B2 (ja) | 2001-05-31 | 2008-11-19 | 伸弥 山中 | Es細胞特異的発現遺伝子 |
| US20030044976A1 (en) * | 2001-08-27 | 2003-03-06 | Advanced Cell Technology | De-differentiation and re-differentiation of somatic cells and production of cells for cell therapies |
| JPWO2003027281A1 (ja) * | 2001-09-20 | 2005-01-06 | 協和醗酵工業株式会社 | 骨格筋間質由来多分化能幹細胞 |
| WO2003027277A1 (en) * | 2001-09-21 | 2003-04-03 | Japan Science And Technology Corporation | Method of screening reporgramming factor, reprogramming factor screened by the method, method of using the reprogramming factor, method of differentiating undifferentiated fused cells and method of constructing cell, tissues and organs |
| JP2004248505A (ja) * | 2001-09-21 | 2004-09-09 | Norio Nakatsuji | 移植抗原の一部または全てを欠除したes細胞由来の未分化な体細胞融合細胞およびその製造 |
| US7588937B2 (en) * | 2001-10-03 | 2009-09-15 | Wisconsin Alumni Research Foundation | Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells |
| DE10162080A1 (de) * | 2001-12-10 | 2003-06-26 | Albrecht Mueller | Verfahren zur Herstellung von Stammzellen mit erhöhtem Entwicklungspotential |
| AU2003238620B2 (en) * | 2002-01-31 | 2008-11-06 | Asahi Techno Glass Corporation | Liquid for frozen storage of primate embryo stem cells and frozen storage method |
| KR20040097200A (ko) | 2002-03-26 | 2004-11-17 | 김소운 | 3차원 안경 시뮬레이션 시스템 및 방법 |
| US7422736B2 (en) * | 2002-07-26 | 2008-09-09 | Food Industry Research And Development Institute | Somatic pluripotent cells |
| US20040048297A1 (en) * | 2002-07-30 | 2004-03-11 | Gene Logic, Inc. | Nucleic acid detection assay control genes |
| JP3736517B2 (ja) | 2002-11-13 | 2006-01-18 | 学校法人近畿大学 | 体細胞核初期化因子 |
| AU2003901099A0 (en) | 2003-03-11 | 2003-03-27 | Es Cell International Pte Ltd. | Methods of inducing differentiation of stem cells |
| WO2004099372A2 (en) | 2003-05-01 | 2004-11-18 | University Of Florida | Anti-scarring ribozymes and methods |
| US9567591B2 (en) | 2003-05-15 | 2017-02-14 | Mello Biotechnology, Inc. | Generation of human embryonic stem-like cells using intronic RNA |
| EP1637589A4 (en) * | 2003-05-16 | 2007-01-10 | Kyowa Hakko Kogyo Kk | NEW STEM CELL DERIVED FROM ADULT FABRIC AND THEIR USE |
| JP4644663B2 (ja) | 2003-06-03 | 2011-03-02 | セル ジェネシス インコーポレイテッド | ペプチド開裂部位を用いた単一ベクターからの組換えポリペプチドの高められた発現のための構成と方法 |
| WO2005010524A1 (en) * | 2003-06-04 | 2005-02-03 | Curis, Inc. | Stem cell-based methods for identifying and characterizing agents |
| WO2005033297A1 (en) | 2003-09-19 | 2005-04-14 | The Rockefeller University | Compositions, methods and kits relating to reprogramming adult differentiated cells and production of embryonic stem cell-like cells |
| JP2005095027A (ja) | 2003-09-22 | 2005-04-14 | Reprocell Inc | 細胞の未分化状態マーカープロモーターおよびその利用 |
| WO2005035741A1 (ja) | 2003-10-09 | 2005-04-21 | Kyowa Hakko Kogyo Co., Ltd. | ゲノムが改変された細胞 |
| ES2398239T3 (es) | 2003-11-10 | 2013-03-14 | The Scripps Research Institute | Composiciones y procedimientos para inducir la desdiferenciación celular |
| US7682828B2 (en) * | 2003-11-26 | 2010-03-23 | Whitehead Institute For Biomedical Research | Methods for reprogramming somatic cells |
| JP2005155461A (ja) * | 2003-11-26 | 2005-06-16 | Sanyo Electric Co Ltd | 圧縮機 |
| US20070269790A1 (en) | 2003-12-01 | 2007-11-22 | Technion Research & Development | Methods of Generating Stem Cells and Embryonic Bodies Carrying Disease-Causing Mutations and Methods of Using same for Studying Genetic Disorders |
| JP4340736B2 (ja) | 2004-01-15 | 2009-10-07 | 国立大学法人福井大学 | レポーター遺伝子を組み込んだベクター |
| US7964401B2 (en) | 2004-02-19 | 2011-06-21 | Kyoto University | Screening method for somatic cell nuclear reprogramming substance affecting ECAT2 and ECAT3 |
| BRPI0509179A (pt) | 2004-03-23 | 2007-09-18 | Daiichi Asubio Pharma Co Ltd | método de crescimento de célula tronco pluripotente |
| WO2005117557A2 (en) * | 2004-06-01 | 2005-12-15 | San Diego State University Foundation | Expression system |
| WO2006006692A1 (ja) * | 2004-07-08 | 2006-01-19 | Japan Science And Technology Agency | 低血清培養で選択的に増殖する動物組織遍在性の分化多能性細胞 |
| WO2006084229A2 (en) | 2004-07-15 | 2006-08-10 | Primegen Biotech, Llc | Use of nuclear material to therapeutically reprogram differentiated cells |
| FR2873175B1 (fr) * | 2004-07-16 | 2006-10-20 | Poclain Hydraulics Ind Soc Par | Circuit hydraulique comprenant un selecteur multifonction |
| WO2006017476A2 (en) * | 2004-08-02 | 2006-02-16 | The Research Foundation Of State University Of New York | Amino functionalized ormosil nanoparticles as delivery vehicles |
| WO2006035741A1 (ja) | 2004-09-29 | 2006-04-06 | Dainippon Sumitomo Pharma Co., Ltd. | Es細胞特異的発現遺伝子及びその利用 |
| AU2005326784B2 (en) | 2004-10-08 | 2012-03-15 | Virxsys Corporation | Use of RNA trans-splicing for antibody gene transfer and antibody polypeptide production |
| US20060095319A1 (en) * | 2004-10-29 | 2006-05-04 | Cardwell Carlzo B | Marketing and compensation method |
| US20060182724A1 (en) | 2005-02-15 | 2006-08-17 | Riordan Neil H | Method for expansion of stem cells |
| JPWO2006093172A1 (ja) * | 2005-02-28 | 2008-08-07 | 財団法人先端医療振興財団 | 成体幹細胞の体外増幅方法 |
| US20070033061A1 (en) * | 2005-04-05 | 2007-02-08 | Achaogen, Inc. | Business methods for commercializing antimicrobial and cytotoxic compounds |
| FR2885536B1 (fr) * | 2005-05-12 | 2007-07-27 | Roquette Freres | Composition a base d'ethers de dianhydrohexitol pour le traitement d'une matiere autre que le corps humain |
| WO2007026255A2 (en) | 2005-06-22 | 2007-03-08 | Universitetet I Oslo | Dedifferentiated cells and methods of making and using dedifferentiated cells |
| TW200745332A (en) | 2005-07-21 | 2007-12-16 | Abbott Lab | Multiple gene expression including sorf constructs and methods with polyproteins, pro-proteins, and proteolysis |
| CA2659945C (en) | 2005-08-03 | 2014-12-16 | Advanced Cell Technology, Inc. | Improved methods of reprogramming animal somatic cells |
| JP2007117081A (ja) * | 2005-09-30 | 2007-05-17 | Institute Of Physical & Chemical Research | 核移植卵子の作製方法 |
| WO2007054720A1 (en) | 2005-11-11 | 2007-05-18 | The University Court Of University Of Edinburgh | Reprogramming and genetic modification of cells |
| US8278104B2 (en) * | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| US8129187B2 (en) * | 2005-12-13 | 2012-03-06 | Kyoto University | Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2 |
| AU2006325975B2 (en) * | 2005-12-13 | 2011-12-08 | Kyoto University | Nuclear reprogramming factor |
| US20090227032A1 (en) * | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
| CN101389761A (zh) | 2006-02-27 | 2009-03-18 | 银怎株式会社 | 使用bmi-1使星形胶质细胞去分化成为神经干细胞 |
| US20090252711A1 (en) * | 2006-05-11 | 2009-10-08 | Andrew Craig Boquest | Stem Cells And Methods Of Making And Using Stem Cells |
| US20090028835A1 (en) | 2006-09-08 | 2009-01-29 | Michigan State University | Human transcriptome corresponding to human oocytes and use of said genes or the corresponding polypeptides to trans-differentiate somatic cells |
| JP2008099662A (ja) * | 2006-09-22 | 2008-05-01 | Institute Of Physical & Chemical Research | 幹細胞の培養方法 |
| US20080132803A1 (en) * | 2006-11-30 | 2008-06-05 | Hyman Friedlander | Method and system for doing business by mining the placental-chord complex |
| WO2008089351A1 (en) | 2007-01-17 | 2008-07-24 | Wisconsin Alumni Research Foundation | Improved culture of stem cells |
| US8158415B2 (en) | 2007-02-27 | 2012-04-17 | Procell Therapeutics Inc. | Combined use of cell permeable Nanog and Oct4 for increasing self-renewal and suppressing differentiation of stem cells |
| WO2008105566A1 (en) | 2007-02-27 | 2008-09-04 | Korea Stem Cell Bank | System for providing stem cell services using internet and method thereof |
| DK3399025T3 (da) * | 2007-03-23 | 2025-06-16 | Wisconsin Alumni Res Found | Omprogrammering af somatiske celler |
| CA2683056C (en) | 2007-04-07 | 2020-03-24 | Whitehead Institute For Biomedical Research | Reprogramming of somatic cells |
| JP2010528613A (ja) | 2007-05-29 | 2010-08-26 | クリストファー ビー. リード, | 多能細胞集団を産生する方法およびその使用 |
| CA2688539A1 (en) * | 2007-05-30 | 2008-12-11 | The General Hospital Corporation | Methods of generating pluripotent cells from somatic cells |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| US9213999B2 (en) * | 2007-06-15 | 2015-12-15 | Kyoto University | Providing iPSCs to a customer |
| WO2009032456A2 (en) | 2007-08-01 | 2009-03-12 | Primegen Biotech Llc | Non-viral delivery of transcription factors that reprogram human somatic cells into a stem cell-like state |
| EP2190976A4 (en) | 2007-08-10 | 2010-10-20 | Univ Dayton | METHOD FOR PRODUCING PLURIPOTENTAL STEM CELL LENGTH CELLS |
| EP3078738B1 (en) * | 2007-08-31 | 2020-05-20 | Whitehead Institute for Biomedical Research | Wnt pathway stimulation in reprogramming somatic cells |
| CA2660123C (en) * | 2007-10-31 | 2017-05-09 | Kyoto University | Nuclear reprogramming method |
| US20110151447A1 (en) * | 2007-11-06 | 2011-06-23 | Children's Medical Center Corporation | Method to produce induced pluripotent stem (ips) cells from non-embryonic human cells |
| US9005966B2 (en) | 2007-11-19 | 2015-04-14 | The Regents Of The University Of California | Generation of pluripotent cells from fibroblasts |
| US9683232B2 (en) * | 2007-12-10 | 2017-06-20 | Kyoto University | Efficient method for nuclear reprogramming |
| JP5558097B2 (ja) * | 2007-12-10 | 2014-07-23 | 国立大学法人京都大学 | 効率的な核初期化方法 |
| US20090191171A1 (en) * | 2008-01-18 | 2009-07-30 | Yupo Ma | Reprogramming of Differentiated Progenitor or Somatic Cells Using Homologous Recombination |
| KR101481164B1 (ko) | 2008-01-30 | 2015-01-09 | 주식회사 미래셀바이오 | 체세포 유래 다능성 줄기세포의 제조 방법 |
| US20110014164A1 (en) | 2008-02-15 | 2011-01-20 | President And Fellows Of Harvard College | Efficient induction of pluripotent stem cells using small molecule compounds |
| EP2268796A1 (en) | 2008-03-17 | 2011-01-05 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Vectors and methods for generating vector-free induced pluripotent stem (ips) cells using site-specific recombination |
| WO2009117439A2 (en) * | 2008-03-17 | 2009-09-24 | The Scripps Research Institute | Combined chemical and genetic approaches for generation of induced pluripotent stem cells |
| CN101250502A (zh) | 2008-04-01 | 2008-08-27 | 中国科学院上海生命科学研究院 | 一种诱导的多潜能干细胞的制备方法 |
| CN101550406B (zh) * | 2008-04-03 | 2016-02-10 | 北京大学 | 制备多潜能干细胞的方法,试剂盒及用途 |
| US20100021437A1 (en) * | 2008-04-07 | 2010-01-28 | The McLean Hospital Corporation Whitehead Institute for Biomedical Research | Neural stem cells derived from induced pluripotent stem cells |
| US20100279404A1 (en) | 2008-05-02 | 2010-11-04 | Shinya Yamanaka | Method of nuclear reprogramming |
| EP2128245A1 (en) | 2008-05-27 | 2009-12-02 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Generation of induced pluripotent stem (iPS) cells |
| EP3447128A1 (en) | 2008-06-04 | 2019-02-27 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of ips cells using non-viral approach |
| JP5553178B2 (ja) | 2008-07-31 | 2014-07-16 | 国立大学法人岐阜大学 | 効率的な人工多能性幹細胞の樹立方法 |
| US8298825B1 (en) | 2008-08-25 | 2012-10-30 | The General Hospital Corporation | TGF-beta receptor inhibitors to enhance direct reprogramming |
| US20100062534A1 (en) * | 2008-09-09 | 2010-03-11 | The General Hospital Corporation | Inducible lentiviral vectors for reprogramming somatic cells |
| EP3450545B1 (en) | 2008-10-24 | 2023-08-23 | Wisconsin Alumni Research Foundation | Pluripotent stem cells obtained by non-viral reprogramming |
| JP4992952B2 (ja) | 2009-11-02 | 2012-08-08 | 住友電気工業株式会社 | 交通信号制御分析装置 |
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