MD1813B2 - Derivati purificati de ciclodextrina ai eterilor sulfoalchilici sau amestecurile lor, complex clatrat al derivatilor de ciclodextrina cu continut de medicament si compozitie farmaceutica - Google Patents

Derivati purificati de ciclodextrina ai eterilor sulfoalchilici sau amestecurile lor, complex clatrat al derivatilor de ciclodextrina cu continut de medicament si compozitie farmaceutica Download PDF

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Publication number
MD1813B2
MD1813B2 MD96-0306A MD960306A MD1813B2 MD 1813 B2 MD1813 B2 MD 1813B2 MD 960306 A MD960306 A MD 960306A MD 1813 B2 MD1813 B2 MD 1813B2
Authority
MD
Moldova
Prior art keywords
cyclodextrin derivatives
sulphoalkyl
ethers
mixtures
pharmaceutical composition
Prior art date
Application number
MD96-0306A
Other languages
English (en)
Other versions
MD1813C2 (ro
Inventor
Valentino J Stella
Roger Rajewski
Original Assignee
Univ Kansas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Univ Kansas filed Critical Univ Kansas
Publication of MD1813B2 publication Critical patent/MD1813B2/ro
Publication of MD1813C2 publication Critical patent/MD1813C2/ro

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MD96-0306A 1992-07-27 1993-07-26 Derivaţi purificaţi de ciclodextrină ai eterilor sulfoalchilici sau amestecurile lor, complex clatrat al derivaţilor de ciclodextrină cu conţinut de medicament şi compoziţie farmaceutică MD1813C2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/918,702 US5376645A (en) 1990-01-23 1992-07-27 Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
PCT/US1993/006880 WO1994002518A1 (en) 1992-07-27 1993-07-26 Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof

Publications (2)

Publication Number Publication Date
MD1813B2 true MD1813B2 (ro) 2001-12-31
MD1813C2 MD1813C2 (ro) 2002-08-31

Family

ID=25440795

Family Applications (1)

Application Number Title Priority Date Filing Date
MD96-0306A MD1813C2 (ro) 1992-07-27 1993-07-26 Derivaţi purificaţi de ciclodextrină ai eterilor sulfoalchilici sau amestecurile lor, complex clatrat al derivaţilor de ciclodextrină cu conţinut de medicament şi compoziţie farmaceutică

Country Status (16)

Country Link
US (1) US5376645A (ro)
EP (1) EP0620828B2 (ro)
JP (1) JP3393253B2 (ro)
KR (1) KR100279111B1 (ro)
AT (1) ATE217325T1 (ro)
AU (1) AU672814B2 (ro)
CA (1) CA2119154C (ro)
DE (1) DE69331900T3 (ro)
DK (1) DK0620828T4 (ro)
ES (1) ES2176206T5 (ro)
GE (1) GEP19991649B (ro)
MD (1) MD1813C2 (ro)
PT (1) PT620828E (ro)
RU (1) RU2113442C1 (ro)
TJ (1) TJ275B (ro)
WO (1) WO1994002518A1 (ro)

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PT620828E (pt) 2002-10-31
DE69331900T2 (de) 2003-01-16
DK0620828T3 (da) 2002-08-26
MD1813C2 (ro) 2002-08-31
EP0620828B1 (en) 2002-05-08
DK0620828T4 (da) 2008-11-03
TJ275B (en) 2000-10-05
KR100279111B1 (ko) 2001-03-02
ATE217325T1 (de) 2002-05-15
AU4779993A (en) 1994-02-14
US5376645A (en) 1994-12-27
JPH06511513A (ja) 1994-12-22
EP0620828A1 (en) 1994-10-26
EP0620828A4 (en) 1996-05-15
RU2113442C1 (ru) 1998-06-20
DE69331900T3 (de) 2009-03-26
EP0620828B2 (en) 2008-07-09
ES2176206T3 (es) 2002-12-01
ES2176206T5 (es) 2008-12-01
GEP19991649B (en) 1999-06-14
CA2119154C (en) 1998-06-16
DE69331900D1 (de) 2002-06-13
WO1994002518A1 (en) 1994-02-03
JP3393253B2 (ja) 2003-04-07
CA2119154A1 (en) 1994-02-03

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