DK0889056T3 - Process for making a cyclodextrin - Google Patents
Process for making a cyclodextrinInfo
- Publication number
- DK0889056T3 DK0889056T3 DK98304785T DK98304785T DK0889056T3 DK 0889056 T3 DK0889056 T3 DK 0889056T3 DK 98304785 T DK98304785 T DK 98304785T DK 98304785 T DK98304785 T DK 98304785T DK 0889056 T3 DK0889056 T3 DK 0889056T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyclodextrin
- base
- residual
- alkyl sultone
- added
- Prior art date
Links
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 5
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title abstract 4
- -1 Sulfoalkyl ether Chemical compound 0.000 abstract 4
- 239000007858 starting material Substances 0.000 abstract 2
- 229940097362 cyclodextrins Drugs 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5149797P | 1997-07-01 | 1997-07-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0889056T3 true DK0889056T3 (da) | 2006-07-17 |
Family
ID=21971666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98304785T DK0889056T3 (da) | 1997-07-01 | 1998-06-17 | Process for making a cyclodextrin |
Country Status (10)
Country | Link |
---|---|
US (1) | US6153746A (da) |
EP (1) | EP0889056B1 (da) |
JP (1) | JP3272669B2 (da) |
AT (1) | ATE323110T1 (da) |
BR (1) | BR9802331A (da) |
CA (1) | CA2241774C (da) |
DE (1) | DE69834154T2 (da) |
DK (1) | DK0889056T3 (da) |
ES (1) | ES2257795T3 (da) |
PT (1) | PT889056E (da) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6479467B1 (en) * | 1999-12-16 | 2002-11-12 | Eastman Chemical Company | Cyclodextrin ethers |
CA2726789A1 (en) * | 2000-02-05 | 2001-11-08 | Theravance, Inc. | Cyclodextrin containing glycopeptide antibiotic compositions |
US20030028014A1 (en) * | 2001-04-26 | 2003-02-06 | Chris Sikorski | Agglomerated modified cyclodextrin and process for making same |
DE60221238T2 (de) * | 2001-05-01 | 2007-10-31 | Pfizer Products Inc., Groton | Herstellungsverfahren für niedrig dosierte pharmazeutische zusammensetzung |
CA2543443A1 (en) * | 2003-10-31 | 2005-05-12 | The University Of Kansas | Sulfoalkyl ether-alkyl ether cyclodextrin derivatives |
EP1729724A4 (en) | 2003-12-31 | 2008-07-23 | Cydex Inc | INHALATION FORMULATION WITH SULFOALKYL ETHER GAMMA CYCLODEXTRIN AND CORTICOSTEROID |
US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
RU2006141358A (ru) | 2004-04-23 | 2008-05-27 | Сайдекс, Инк. (Us) | Препаративная форма для ингалятора сухого порошка, содержащая простой сульфоалкиловый эфир циклодекстрина |
US20100204178A1 (en) | 2006-10-02 | 2010-08-12 | James Cloyd | Novel parenteral carbamazepine formulation |
AU2011204957B2 (en) * | 2005-10-26 | 2013-12-05 | Cydex Pharmaceuticals, Inc | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
EP2583668B1 (en) | 2005-10-26 | 2014-10-08 | CyDex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
CN102327617B (zh) * | 2005-10-26 | 2014-08-20 | 锡德克斯药物公司 | 磺基烷基醚环糊精组合物和其制备方法 |
US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
US20090239942A1 (en) * | 2006-09-15 | 2009-09-24 | Cloyd James C | Topiramate Compositions and Methods of Making and Using the Same |
WO2008065142A1 (en) * | 2006-11-29 | 2008-06-05 | N.V. Organon | Stabilized solution of rocuronium comprising a sulfoalkyl-ether-beta-cyclodextrin derivative |
MX2009011619A (es) | 2007-04-27 | 2010-01-18 | Cydex Pharmaceuticals Inc | Formulaciones que contienen clopidogrel y eter sulfoalquilico-ciclodextrina y metodos de uso. |
ES2493641T3 (es) * | 2007-06-28 | 2014-09-12 | Cydex Pharmaceuticals, Inc. | Administración nasal de soluciones acuosas de corticosteroides |
US7635773B2 (en) * | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
BRPI0919668A2 (pt) | 2008-10-21 | 2018-05-29 | Onyx Therapeutics, Inc. | terapia de combinação com epóxi-cetonas de peptídeo |
US10463677B2 (en) | 2008-11-07 | 2019-11-05 | Cydex Pharmaceuticals, Inc. | Composition containing sulfoalkyl ether cyclodextrin and latanoprost |
WO2010132711A1 (en) | 2009-05-13 | 2010-11-18 | Cydex Pharmaceuticals, Inc. | Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same |
US11020363B2 (en) | 2009-05-29 | 2021-06-01 | Cydex Pharmaceuticals, Inc. | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same |
EA022890B1 (ru) | 2009-05-29 | 2016-03-31 | Сидекс Фармасьютикалз, Инк. | Инъецируемые композиции мелфалана, содержащие производное циклодекстрина, и способы их применения |
US8492538B1 (en) | 2009-06-04 | 2013-07-23 | Jose R. Matos | Cyclodextrin derivative salts |
TWI544922B (zh) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠(olopatadine)眼用組成物 |
TW201336527A (zh) | 2012-02-10 | 2013-09-16 | Alcon Res Ltd | 具增強的穩定性之水性藥學組成物 |
DK2814849T3 (da) | 2012-02-15 | 2020-03-09 | Cydex Pharmaceuticals Inc | Fremgangsmåde til fremstilling af cyclodextrin-derivater |
KR101633479B1 (ko) | 2012-02-28 | 2016-07-08 | 사이덱스 파마슈티칼스, 인크. | 알킬화된 시클로덱스트린 조성물 및 이의 제조 및 사용 방법 |
KR101905937B1 (ko) * | 2012-03-30 | 2018-10-08 | 자피오텍 게엠베하 | 안토시아니딘 복합체 |
CA2873044C (en) | 2012-05-08 | 2021-01-26 | Onyx Therapeutics, Inc. | Cylodextrin complexation methods for formulating peptide proteasome inhibitors |
MX360192B (es) | 2012-10-22 | 2018-10-24 | Cydex Pharmaceuticals Inc | Composiciones de ciclodextrinas alquiladas y procesos para preparar y usar las mismas. |
GB201312737D0 (en) * | 2013-07-17 | 2013-08-28 | Univ Greenwich | Cyclodextrin |
CN103694376B (zh) * | 2014-01-10 | 2016-04-13 | 凯莱英医药集团(天津)股份有限公司 | 一种制备磺丁基醚-β-环糊精的方法 |
US10851184B2 (en) | 2014-08-22 | 2020-12-01 | Cydex Pharmaceuticals, Inc. | Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same |
WO2016149685A1 (en) | 2015-03-19 | 2016-09-22 | Cydex Pharmaceuticals, Inc. | Compositions containing silymarin and sulfoalkyl ether cyclodextrin and methods of using the same |
CN104892797B (zh) * | 2015-05-28 | 2017-03-22 | 天津大学 | 特定平均取代度磺丁基醚‑β‑环糊精的合成方法 |
CN106749770A (zh) * | 2015-11-20 | 2017-05-31 | 天津市通航科技有限公司 | 一种微波辐射/碱耦合制备不同取代度磺丁基醚-β-环糊精的方法 |
US11274164B2 (en) | 2017-02-07 | 2022-03-15 | Biophore India Pharmaceuticals Pvt. Ltd. | Method for the preparation of sulfobutylether beta cyclodextrin sodium |
US20180318249A1 (en) | 2017-05-03 | 2018-11-08 | Cydex Pharmaceuticals, Inc. | Composition containing cyclodextrin and busulfan |
JP7336657B2 (ja) | 2018-10-15 | 2023-09-01 | 国立大学法人大阪大学 | 環状オリゴ糖及びその製造方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3426011A (en) * | 1967-02-13 | 1969-02-04 | Corn Products Co | Cyclodextrins with anionic properties |
KR0166088B1 (ko) * | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
US5376645A (en) * | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
-
1998
- 1998-06-17 PT PT98304785T patent/PT889056E/pt unknown
- 1998-06-17 EP EP98304785A patent/EP0889056B1/en not_active Expired - Lifetime
- 1998-06-17 DK DK98304785T patent/DK0889056T3/da active
- 1998-06-17 ES ES98304785T patent/ES2257795T3/es not_active Expired - Lifetime
- 1998-06-17 DE DE69834154T patent/DE69834154T2/de not_active Expired - Lifetime
- 1998-06-17 AT AT98304785T patent/ATE323110T1/de active
- 1998-06-25 JP JP17883198A patent/JP3272669B2/ja not_active Expired - Lifetime
- 1998-06-29 CA CA002241774A patent/CA2241774C/en not_active Expired - Lifetime
- 1998-06-29 US US09/106,983 patent/US6153746A/en not_active Expired - Lifetime
- 1998-07-01 BR BR9802331-4A patent/BR9802331A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BR9802331A (pt) | 2000-09-05 |
DE69834154T2 (de) | 2007-01-25 |
ES2257795T3 (es) | 2006-08-01 |
EP0889056A2 (en) | 1999-01-07 |
JP3272669B2 (ja) | 2002-04-08 |
JPH1160610A (ja) | 1999-03-02 |
DE69834154D1 (de) | 2006-05-24 |
CA2241774A1 (en) | 1999-01-01 |
PT889056E (pt) | 2006-07-31 |
US6153746A (en) | 2000-11-28 |
EP0889056A3 (en) | 1999-04-07 |
EP0889056B1 (en) | 2006-04-12 |
ATE323110T1 (de) | 2006-04-15 |
CA2241774C (en) | 2002-06-25 |
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