ATE323110T1 - Verfahren zur herstellung von einem cyclodextrin - Google Patents

Verfahren zur herstellung von einem cyclodextrin

Info

Publication number
ATE323110T1
ATE323110T1 AT98304785T AT98304785T ATE323110T1 AT E323110 T1 ATE323110 T1 AT E323110T1 AT 98304785 T AT98304785 T AT 98304785T AT 98304785 T AT98304785 T AT 98304785T AT E323110 T1 ATE323110 T1 AT E323110T1
Authority
AT
Austria
Prior art keywords
cyclodextrin
base
residual
alkyl sultone
added
Prior art date
Application number
AT98304785T
Other languages
English (en)
Inventor
Constantine Sklavounos
Bharat Kiritkumar Shah
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE323110T1 publication Critical patent/ATE323110T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT98304785T 1997-07-01 1998-06-17 Verfahren zur herstellung von einem cyclodextrin ATE323110T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5149797P 1997-07-01 1997-07-01

Publications (1)

Publication Number Publication Date
ATE323110T1 true ATE323110T1 (de) 2006-04-15

Family

ID=21971666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98304785T ATE323110T1 (de) 1997-07-01 1998-06-17 Verfahren zur herstellung von einem cyclodextrin

Country Status (10)

Country Link
US (1) US6153746A (de)
EP (1) EP0889056B1 (de)
JP (1) JP3272669B2 (de)
AT (1) ATE323110T1 (de)
BR (1) BR9802331A (de)
CA (1) CA2241774C (de)
DE (1) DE69834154T2 (de)
DK (1) DK0889056T3 (de)
ES (1) ES2257795T3 (de)
PT (1) PT889056E (de)

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US6479467B1 (en) * 1999-12-16 2002-11-12 Eastman Chemical Company Cyclodextrin ethers
ATE416791T1 (de) * 2000-05-02 2008-12-15 Theravance Inc Zusammensetzung die eine zyklodextrin und ein glykopeptid-antibiotikum enthält
US20030028014A1 (en) * 2001-04-26 2003-02-06 Chris Sikorski Agglomerated modified cyclodextrin and process for making same
PT1383482E (pt) * 2001-05-01 2007-09-20 Pfizer Prod Inc Método para o fabrico de uma composição farmacêutica de baixa dosagem tendo distribuição e potência de fármaco uniforme
EP1678211A4 (de) * 2003-10-31 2008-04-02 Univ Kansas Sulfoalkylether-alkylether-cyclodextrinderivate
KR20070007075A (ko) 2003-12-31 2007-01-12 사이덱스 인크 술포알킬 에테르 시클로덱스트린 및 코르티코스테로이드를함유한 흡입용 제형
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
CN101098678A (zh) 2004-04-23 2008-01-02 锡德克斯公司 含有磺基烷基醚环糊精的dpi制剂
US20100204178A1 (en) 2006-10-02 2010-08-12 James Cloyd Novel parenteral carbamazepine formulation
RU2417103C2 (ru) * 2005-10-26 2011-04-27 Сайдекс Фармасьютикалз, Инк. Композиции простого сульфоалкилового эфира циклодекстрина и способы их получения
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
CN102327617B (zh) * 2005-10-26 2014-08-20 锡德克斯药物公司 磺基烷基醚环糊精组合物和其制备方法
AU2011204957B2 (en) * 2005-10-26 2013-12-05 Cydex Pharmaceuticals, Inc Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
PL2952197T3 (pl) * 2005-10-26 2017-09-29 Cydex Pharmaceuticals, Inc. Kompozycje eteru sulfoalkilowego cyklodekstryny i sposoby ich wytwarzania
US20090239942A1 (en) 2006-09-15 2009-09-24 Cloyd James C Topiramate Compositions and Methods of Making and Using the Same
WO2008065142A1 (en) * 2006-11-29 2008-06-05 N.V. Organon Stabilized solution of rocuronium comprising a sulfoalkyl-ether-beta-cyclodextrin derivative
RU2470636C2 (ru) 2007-04-27 2012-12-27 Сайдекс Фамэсьютиклз, Инк. Композиция клопидогреля и сульфоалкилового эфира циклодекстрина (варианты) и способы лечения заболеваний посредством названной композиции (варианты)
US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
ES2493641T3 (es) * 2007-06-28 2014-09-12 Cydex Pharmaceuticals, Inc. Administración nasal de soluciones acuosas de corticosteroides
US7635773B2 (en) * 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
JP5675629B2 (ja) 2008-10-21 2015-02-25 オニキス セラピューティクス， インク．Ｏｎｙｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． ペプチドエポキシケトンを用いた併用療法
US10463677B2 (en) 2008-11-07 2019-11-05 Cydex Pharmaceuticals, Inc. Composition containing sulfoalkyl ether cyclodextrin and latanoprost
ES2769949T3 (es) 2009-05-13 2020-06-29 Cydex Pharmaceuticals Inc Composiciones farmacéuticas que comprenden prasugrel y derivados de ciclodextrina y métodos de preparación y uso de las mismas
ES2767880T3 (es) 2009-05-29 2020-06-18 Cydex Pharmaceuticals Inc Composiciones inyectables de melfalán que comprenden un derivado de ciclodextrina y métodos de preparación y uso de las mismas
US11020363B2 (en) 2009-05-29 2021-06-01 Cydex Pharmaceuticals, Inc. Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
US8492538B1 (en) 2009-06-04 2013-07-23 Jose R. Matos Cyclodextrin derivative salts
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
TW201336527A (zh) 2012-02-10 2013-09-16 Alcon Res Ltd 具增強的穩定性之水性藥學組成物
PL3702374T3 (pl) 2012-02-15 2022-11-21 Cydex Pharmaceuticals, Inc. Sposób wytwarzania pochodnych cyklodekstryny
WO2013130666A1 (en) * 2012-02-28 2013-09-06 Cydex Pharmaceuticals, Inc. Alkylated cyclodextrin compositions and processes for preparing and using the same
CN104302673B (zh) * 2012-03-30 2017-09-22 赛博尔泰克股份公司 花青素复合物
MX364393B (es) 2012-05-08 2019-04-24 Onyx Therapeutics Inc Procedimientos para la formacion de complejos de ciclodextrina para formular inhibidores del proteasoma peptidico.
UA121095C2 (uk) 2012-10-22 2020-04-10 Сідекс Фармасьютікалс, Інк. Композиції алкілованого циклодекстрину і способи їх одержання і застосування
GB201312737D0 (en) * 2013-07-17 2013-08-28 Univ Greenwich Cyclodextrin
CN103694376B (zh) 2014-01-10 2016-04-13 凯莱英医药集团（天津）股份有限公司 一种制备磺丁基醚-β-环糊精的方法
EP3183295B1 (de) * 2014-08-22 2023-08-02 CyDex Pharmaceuticals, Inc. Fraktionierte alkylierte cyclodextrinzusammensetzungen und verfahren zur herstellung und verwendung davon
EP3270941B1 (de) 2015-03-19 2021-05-26 Cydex Pharmaceuticals, Inc. Zusammensetzungen mit silymarin und sulfoalkylethercyclodextrin und verfahren zur verwendung davon
CN104892797B (zh) * 2015-05-28 2017-03-22 天津大学 特定平均取代度磺丁基醚‑β‑环糊精的合成方法
CN106749770A (zh) * 2015-11-20 2017-05-31 天津市通航科技有限公司 一种微波辐射/碱耦合制备不同取代度磺丁基醚-β-环糊精的方法
WO2018146698A1 (en) 2017-02-07 2018-08-16 Biophore India Pharmaceuticals Pvt. Ltd. Improved method for the preparation of sulfobutylether beta cyclodextrin sodium
BR112019023074A2 (pt) 2017-05-03 2020-06-09 Cydex Pharmaceuticals Inc composição contendo ciclodextrina e bussulfano
JP7336657B2 (ja) 2018-10-15 2023-09-01 国立大学法人大阪大学 環状オリゴ糖及びその製造方法
WO2021101842A1 (en) * 2019-11-18 2021-05-27 Cydex Pharmaceuticals, Inc. Alkylated cyclodextrin compositions and processes for preparing and using the same
JP2023551145A (ja) 2020-11-18 2023-12-07 ベクソン バイオメディカル，インク． 医薬化合物の錯化剤塩製剤

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* Cited by examiner, † Cited by third party
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US3426011A (en) * 1967-02-13 1969-02-04 Corn Products Co Cyclodextrins with anionic properties
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5681828A (en) 1995-12-19 1997-10-28 Pitha; Josef Selective alkylations of cyclodextrins leading to derivatives which have a rigidly extended cavity

Also Published As

Publication number Publication date
CA2241774C (en) 2002-06-25
DE69834154D1 (de) 2006-05-24
ES2257795T3 (es) 2006-08-01
EP0889056B1 (de) 2006-04-12
US6153746A (en) 2000-11-28
CA2241774A1 (en) 1999-01-01
DK0889056T3 (da) 2006-07-17
BR9802331A (pt) 2000-09-05
JP3272669B2 (ja) 2002-04-08
EP0889056A2 (de) 1999-01-07
PT889056E (pt) 2006-07-31
JPH1160610A (ja) 1999-03-02
EP0889056A3 (de) 1999-04-07
DE69834154T2 (de) 2007-01-25

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