ATE323110T1 - Verfahren zur herstellung von einem cyclodextrin - Google Patents

Verfahren zur herstellung von einem cyclodextrin

Info

Publication number
ATE323110T1
ATE323110T1 AT98304785T AT98304785T ATE323110T1 AT E323110 T1 ATE323110 T1 AT E323110T1 AT 98304785 T AT98304785 T AT 98304785T AT 98304785 T AT98304785 T AT 98304785T AT E323110 T1 ATE323110 T1 AT E323110T1
Authority
AT
Austria
Prior art keywords
cyclodextrin
base
residual
alkyl sultone
added
Prior art date
Application number
AT98304785T
Other languages
English (en)
Inventor
Constantine Sklavounos
Bharat Kiritkumar Shah
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE323110T1 publication Critical patent/ATE323110T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT98304785T 1997-07-01 1998-06-17 Verfahren zur herstellung von einem cyclodextrin ATE323110T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5149797P 1997-07-01 1997-07-01

Publications (1)

Publication Number Publication Date
ATE323110T1 true ATE323110T1 (de) 2006-04-15

Family

ID=21971666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98304785T ATE323110T1 (de) 1997-07-01 1998-06-17 Verfahren zur herstellung von einem cyclodextrin

Country Status (10)

Country Link
US (1) US6153746A (de)
EP (1) EP0889056B1 (de)
JP (1) JP3272669B2 (de)
AT (1) ATE323110T1 (de)
BR (1) BR9802331A (de)
CA (1) CA2241774C (de)
DE (1) DE69834154T2 (de)
DK (1) DK0889056T3 (de)
ES (1) ES2257795T3 (de)
PT (1) PT889056E (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
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US6479467B1 (en) * 1999-12-16 2002-11-12 Eastman Chemical Company Cyclodextrin ethers
EP1278549B1 (de) * 2000-05-02 2008-12-10 Theravance, Inc. Zusammensetzung die eine zyklodextrin und ein glykopeptid-antibiotikum enthält
US20030028014A1 (en) * 2001-04-26 2003-02-06 Chris Sikorski Agglomerated modified cyclodextrin and process for making same
IL158390A0 (en) * 2001-05-01 2004-05-12 Pfizer Prod Inc Method for manufacturing a low dose pharmaceutical composition
WO2005042584A2 (en) * 2003-10-31 2005-05-12 The University Of Kansas Sulfoalkyl ether-alkyl ether cyclodextrin derivatives
BRPI0418276B8 (pt) 2003-12-31 2021-05-25 Cydex Pharmaceuticals Inc formulação líquida inalável compreeendendo budesonida
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
PL2708225T3 (pl) * 2004-04-23 2019-07-31 Cydex Pharmaceuticals, Inc. Formulacja DPI zawierająca eter sulfoalkilowy cyklodekstryny
US20100204178A1 (en) 2006-10-02 2010-08-12 James Cloyd Novel parenteral carbamazepine formulation
CN102327617B (zh) * 2005-10-26 2014-08-20 锡德克斯药物公司 磺基烷基醚环糊精组合物和其制备方法
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
RU2417103C2 (ru) * 2005-10-26 2011-04-27 Сайдекс Фармасьютикалз, Инк. Композиции простого сульфоалкилового эфира циклодекстрина и способы их получения
AU2011204957B2 (en) * 2005-10-26 2013-12-05 Cydex Pharmaceuticals, Inc Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
EP2581078B1 (de) 2005-10-26 2014-12-10 Cydex Pharmaceuticals, Inc. Sulfoalkylethercyclodextrin- Zusammensetzungen und deren Herstellungsverfahren
US20090239942A1 (en) 2006-09-15 2009-09-24 Cloyd James C Topiramate Compositions and Methods of Making and Using the Same
WO2008065142A1 (en) * 2006-11-29 2008-06-05 N.V. Organon Stabilized solution of rocuronium comprising a sulfoalkyl-ether-beta-cyclodextrin derivative
US8343995B2 (en) 2007-04-27 2013-01-01 Cydex Pharmaceuticals, Inc. Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin and methods of use
US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
ES2493641T3 (es) * 2007-06-28 2014-09-12 Cydex Pharmaceuticals, Inc. Administración nasal de soluciones acuosas de corticosteroides
US7635773B2 (en) 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
BRPI0919668A2 (pt) 2008-10-21 2018-05-29 Onyx Therapeutics, Inc. terapia de combinação com epóxi-cetonas de peptídeo
US10463677B2 (en) 2008-11-07 2019-11-05 Cydex Pharmaceuticals, Inc. Composition containing sulfoalkyl ether cyclodextrin and latanoprost
CN102625658B (zh) 2009-05-13 2015-01-28 锡德克斯药物公司 包含普拉格雷和环糊精衍生物的药物组合物及其制备和使用方法
PL2434886T3 (pl) 2009-05-29 2020-05-18 Cydex Pharmaceuticals, Inc. Kompozycje do wstrzykiwania melfalanu zawierające pochodną cyklodekstryny i sposoby ich wytwarzania i stosowania
US11020363B2 (en) 2009-05-29 2021-06-01 Cydex Pharmaceuticals, Inc. Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
US8492538B1 (en) 2009-06-04 2013-07-23 Jose R. Matos Cyclodextrin derivative salts
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
TW201336527A (zh) 2012-02-10 2013-09-16 Alcon Res Ltd 具增強的穩定性之水性藥學組成物
EP4083075A1 (de) 2012-02-15 2022-11-02 CyDex Pharmaceuticals, Inc. Verfahren zur herstellung von cyclodextrinderivaten
HK1211311A1 (en) * 2012-02-28 2016-05-20 锡德克斯药物公司 Alkylated cyclodextrin compositions and processes for preparing and using the same
KR101905937B1 (ko) * 2012-03-30 2018-10-08 자피오텍 게엠베하 안토시아니딘 복합체
CN104411334A (zh) 2012-05-08 2015-03-11 欧尼斯治疗公司 用于配制肽蛋白酶体抑制剂的环糊精络合法
HK1213585A1 (zh) * 2012-10-22 2016-07-08 Cydex Pharmaceuticals, Inc. 烷基化环糊精组合物及其制备和使用方法
GB201312737D0 (en) * 2013-07-17 2013-08-28 Univ Greenwich Cyclodextrin
CN103694376B (zh) 2014-01-10 2016-04-13 凯莱英医药集团（天津）股份有限公司 一种制备磺丁基醚-β-环糊精的方法
PT3183295T (pt) 2014-08-22 2023-11-03 Cydex Pharmaceuticals Inc Composições de ciclodextrina alquilada fracionada e processos para preparação e utilização das mesmas
EP4620534A3 (de) 2015-03-19 2025-12-24 CyDex Pharmaceuticals, Inc. Zusammensetzungen mit silymarin und sulfoalkylethercyclodextrin und verfahren zur verwendung davon
CN104892797B (zh) * 2015-05-28 2017-03-22 天津大学 特定平均取代度磺丁基醚‑β‑环糊精的合成方法
CN106749770A (zh) * 2015-11-20 2017-05-31 天津市通航科技有限公司 一种微波辐射/碱耦合制备不同取代度磺丁基醚-β-环糊精的方法
WO2018146698A1 (en) 2017-02-07 2018-08-16 Biophore India Pharmaceuticals Pvt. Ltd. Improved method for the preparation of sulfobutylether beta cyclodextrin sodium
US20180318249A1 (en) 2017-05-03 2018-11-08 Cydex Pharmaceuticals, Inc. Composition containing cyclodextrin and busulfan
JP7336657B2 (ja) 2018-10-15 2023-09-01 国立大学法人大阪大学 環状オリゴ糖及びその製造方法
JP7686639B2 (ja) * 2019-11-18 2025-06-02 サイデックス・ファーマシューティカルズ・インコーポレイテッド アルキル化シクロデキストリン組成物並びにこれを製造及び使用する方法
EP4247340A4 (de) 2020-11-18 2024-10-02 Bexson Biomedical, Inc. Komplexbildnersalzformulierungen von pharmazeutischen verbindungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3426011A (en) * 1967-02-13 1969-02-04 Corn Products Co Cyclodextrins with anionic properties
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5681828A (en) 1995-12-19 1997-10-28 Pitha; Josef Selective alkylations of cyclodextrins leading to derivatives which have a rigidly extended cavity

Also Published As

Publication number Publication date
JP3272669B2 (ja) 2002-04-08
US6153746A (en) 2000-11-28
CA2241774A1 (en) 1999-01-01
EP0889056A2 (de) 1999-01-07
EP0889056B1 (de) 2006-04-12
DE69834154D1 (de) 2006-05-24
EP0889056A3 (de) 1999-04-07
CA2241774C (en) 2002-06-25
DE69834154T2 (de) 2007-01-25
JPH1160610A (ja) 1999-03-02
ES2257795T3 (es) 2006-08-01
BR9802331A (pt) 2000-09-05
PT889056E (pt) 2006-07-31
DK0889056T3 (da) 2006-07-17

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