DE69834154D1 - Verfahren zur Herstellung von einem Cyclodextrin - Google Patents

Verfahren zur Herstellung von einem Cyclodextrin

Info

Publication number
DE69834154D1
DE69834154D1 DE69834154T DE69834154T DE69834154D1 DE 69834154 D1 DE69834154 D1 DE 69834154D1 DE 69834154 T DE69834154 T DE 69834154T DE 69834154 T DE69834154 T DE 69834154T DE 69834154 D1 DE69834154 D1 DE 69834154D1
Authority
DE
Germany
Prior art keywords
cyclodextrin
base
residual
alkyl sultone
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69834154T
Other languages
English (en)
Other versions
DE69834154T2 (de
Inventor
Constantine Sklavounos
Bharat Kiritkumar Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of DE69834154D1 publication Critical patent/DE69834154D1/de
Application granted granted Critical
Publication of DE69834154T2 publication Critical patent/DE69834154T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69834154T 1997-07-01 1998-06-17 Verfahren zur Herstellung von einem Cyclodextrin Expired - Lifetime DE69834154T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5149797P 1997-07-01 1997-07-01
US51497P 1997-07-01

Publications (2)

Publication Number Publication Date
DE69834154D1 true DE69834154D1 (de) 2006-05-24
DE69834154T2 DE69834154T2 (de) 2007-01-25

Family

ID=21971666

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69834154T Expired - Lifetime DE69834154T2 (de) 1997-07-01 1998-06-17 Verfahren zur Herstellung von einem Cyclodextrin

Country Status (10)

Country Link
US (1) US6153746A (de)
EP (1) EP0889056B1 (de)
JP (1) JP3272669B2 (de)
AT (1) ATE323110T1 (de)
BR (1) BR9802331A (de)
CA (1) CA2241774C (de)
DE (1) DE69834154T2 (de)
DK (1) DK0889056T3 (de)
ES (1) ES2257795T3 (de)
PT (1) PT889056E (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6479467B1 (en) * 1999-12-16 2002-11-12 Eastman Chemical Company Cyclodextrin ethers
US6858584B2 (en) * 2000-05-02 2005-02-22 Theravance, Inc. Pharmaceutical compositions containing a glycopeptide antibiotic and a cyclodextrin
US20030028014A1 (en) * 2001-04-26 2003-02-06 Chris Sikorski Agglomerated modified cyclodextrin and process for making same
EA005949B1 (ru) * 2001-05-01 2005-08-25 Пфайзер Продактс Инк. Способ производства фармацевтической композиции низкой дозы
EP1678211A4 (de) * 2003-10-31 2008-04-02 Univ Kansas Sulfoalkylether-alkylether-cyclodextrinderivate
EP1729724A4 (de) 2003-12-31 2008-07-23 Cydex Inc Inhalationsformulierung mit sulfoalkylether-gamma-cyclodextrin und corticosteroid
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
CA2562585A1 (en) 2004-04-23 2005-11-10 Cydex, Inc. Dpi formulation containing sulfoalkyl ether cyclodextrin
US20100204178A1 (en) 2006-10-02 2010-08-12 James Cloyd Novel parenteral carbamazepine formulation
ES2542893T3 (es) 2005-10-26 2015-08-12 Cydex Pharmaceuticals, Inc. Composiciones de sulfoalquiléter ciclodextrina y métodos de preparación de las mismas
AU2011204957B2 (en) * 2005-10-26 2013-12-05 Cydex Pharmaceuticals, Inc Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
CN102327617B (zh) * 2005-10-26 2014-08-20 锡德克斯药物公司 磺基烷基醚环糊精组合物和其制备方法
US20090239942A1 (en) 2006-09-15 2009-09-24 Cloyd James C Topiramate Compositions and Methods of Making and Using the Same
WO2008065142A1 (en) * 2006-11-29 2008-06-05 N.V. Organon Stabilized solution of rocuronium comprising a sulfoalkyl-ether-beta-cyclodextrin derivative
CN104800210B (zh) 2007-04-27 2019-08-06 锡德克斯药物公司 包含氯吡格雷和磺基烷基醚环糊精的制剂和其使用方法
ES2493641T3 (es) * 2007-06-28 2014-09-12 Cydex Pharmaceuticals, Inc. Administración nasal de soluciones acuosas de corticosteroides
US7635773B2 (en) 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
BRPI0919668A2 (pt) 2008-10-21 2018-05-29 Onyx Therapeutics, Inc. terapia de combinação com epóxi-cetonas de peptídeo
WO2010053487A1 (en) 2008-11-07 2010-05-14 Cydex Pharmaceuticals, Inc. Composition containing sulfoalkyl ether cyclodextrin and latanoprost
KR101743591B1 (ko) * 2009-05-13 2017-06-20 사이덱스 파마슈티칼스, 인크. 프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법
MX357677B (es) 2009-05-29 2018-07-19 Cydex Pharmaceuticals Inc Composiciones inyectables de melfalán que comprenden un derivado de ciclodextrina y métodos de fabricación y uso de las mismas.
US11020363B2 (en) 2009-05-29 2021-06-01 Cydex Pharmaceuticals, Inc. Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
US8492538B1 (en) 2009-06-04 2013-07-23 Jose R. Matos Cyclodextrin derivative salts
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
TW201336527A (zh) 2012-02-10 2013-09-16 Alcon Res Ltd 具增強的穩定性之水性藥學組成物
EP2814849B8 (de) 2012-02-15 2020-03-04 CyDex Pharmaceuticals, Inc. Verfahren zur herstellung von cyclodextrinderivaten
RU2747757C2 (ru) * 2012-02-28 2021-05-13 Сидекс Фармасьютикалс, Инк. Композиции алкилированного циклодекстрина и способы их получения и применения
DK2831122T3 (da) * 2012-03-30 2016-05-17 Sapiotec Gmbh Anthocyanidin-kompleks
US10159746B2 (en) 2012-05-08 2018-12-25 Onyx Therapeutics, Inc. Cyclodextrin complexation methods for formulating peptide proteasome inhibitors
UA121095C2 (uk) * 2012-10-22 2020-04-10 Сідекс Фармасьютікалс, Інк. Композиції алкілованого циклодекстрину і способи їх одержання і застосування
GB201312737D0 (en) * 2013-07-17 2013-08-28 Univ Greenwich Cyclodextrin
CN103694376B (zh) * 2014-01-10 2016-04-13 凯莱英医药集团（天津）股份有限公司 一种制备磺丁基醚-β-环糊精的方法
FI3183295T3 (fi) * 2014-08-22 2023-09-25 Cydex Pharmaceuticals Inc Fraktioidut alkyloidut syklodekstriinikoostumukset ja menetelmät niiden valmistamiseksi ja käyttämiseksi
CN108348560A (zh) 2015-03-19 2018-07-31 锡德克斯药物公司 包含水飞蓟素和磺烃基醚环糊精的组合物及其使用方法
CN104892797B (zh) * 2015-05-28 2017-03-22 天津大学 特定平均取代度磺丁基醚‑β‑环糊精的合成方法
CN106749770A (zh) * 2015-11-20 2017-05-31 天津市通航科技有限公司 一种微波辐射/碱耦合制备不同取代度磺丁基醚-β-环糊精的方法
WO2018146698A1 (en) 2017-02-07 2018-08-16 Biophore India Pharmaceuticals Pvt. Ltd. Improved method for the preparation of sulfobutylether beta cyclodextrin sodium
KR20190141244A (ko) 2017-05-03 2019-12-23 사이덱스 파마슈티칼스, 인크. 사이클로덱스트린 및 부설판을 함유하는 조성물
JP7336657B2 (ja) 2018-10-15 2023-09-01 国立大学法人大阪大学 環状オリゴ糖及びその製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3426011A (en) * 1967-02-13 1969-02-04 Corn Products Co Cyclodextrins with anionic properties
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도

Also Published As

Publication number Publication date
ES2257795T3 (es) 2006-08-01
CA2241774A1 (en) 1999-01-01
PT889056E (pt) 2006-07-31
BR9802331A (pt) 2000-09-05
US6153746A (en) 2000-11-28
ATE323110T1 (de) 2006-04-15
EP0889056A2 (de) 1999-01-07
CA2241774C (en) 2002-06-25
JPH1160610A (ja) 1999-03-02
EP0889056B1 (de) 2006-04-12
DE69834154T2 (de) 2007-01-25
DK0889056T3 (da) 2006-07-17
JP3272669B2 (ja) 2002-04-08
EP0889056A3 (de) 1999-04-07

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