JPH0577433B2 - - Google Patents

Info

Publication number
JPH0577433B2
JPH0577433B2 JP86177917A JP17791786A JPH0577433B2 JP H0577433 B2 JPH0577433 B2 JP H0577433B2 JP 86177917 A JP86177917 A JP 86177917A JP 17791786 A JP17791786 A JP 17791786A JP H0577433 B2 JPH0577433 B2 JP H0577433B2
Authority
JP
Japan
Prior art keywords
drug
administration device
container
plunger
drug administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP86177917A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6241668A (ja
Inventor
Edowaado Nyuueru Robaato
Kenesu Rando Hooru
Arekisandaa Fuitsutsus Robaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26289568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0577433(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB858519141A external-priority patent/GB8519141D0/en
Priority claimed from GB858525067A external-priority patent/GB8525067D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JPS6241668A publication Critical patent/JPS6241668A/ja
Publication of JPH0577433B2 publication Critical patent/JPH0577433B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Electrotherapy Devices (AREA)
  • Motorcycle And Bicycle Frame (AREA)
JP61177917A 1985-07-30 1986-07-30 固形微粉状薬物を患者に投与する装置 Granted JPS6241668A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB858519141A GB8519141D0 (en) 1985-07-30 1985-07-30 Administering medicaments to patients
GB8519141 1985-07-30
GB858525067A GB8525067D0 (en) 1985-10-10 1985-10-10 Administering medicaments to patients
GB8525067 1985-10-10

Publications (2)

Publication Number Publication Date
JPS6241668A JPS6241668A (ja) 1987-02-23
JPH0577433B2 true JPH0577433B2 (enExample) 1993-10-26

Family

ID=26289568

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61177917A Granted JPS6241668A (ja) 1985-07-30 1986-07-30 固形微粉状薬物を患者に投与する装置

Country Status (35)

Country Link
US (2) US4811731A (enExample)
EP (1) EP0211595B1 (enExample)
JP (1) JPS6241668A (enExample)
KR (1) KR940002247B1 (enExample)
AT (1) AT396872B (enExample)
AU (1) AU591152B2 (enExample)
BE (1) BE905189A (enExample)
BR (1) BR8603576A (enExample)
CA (1) CA1272917A (enExample)
CH (1) CH672600A5 (enExample)
CY (1) CY1481A (enExample)
DE (2) DE3682457D1 (enExample)
DK (1) DK163640C (enExample)
DO (1) DOP1989004707A (enExample)
ES (1) ES2000781A6 (enExample)
FI (1) FI88112C (enExample)
FR (1) FR2585563B1 (enExample)
GB (1) GB2178965B (enExample)
GR (1) GR861995B (enExample)
HK (1) HK67589A (enExample)
HU (1) HU199306B (enExample)
IE (1) IE59026B1 (enExample)
IL (1) IL79550A (enExample)
IT (1) IT1195984B (enExample)
KE (1) KE3865A (enExample)
LU (1) LU86534A1 (enExample)
MX (1) MX171389B (enExample)
NL (1) NL8601949A (enExample)
NO (1) NO166268C (enExample)
NZ (1) NZ217006A (enExample)
PH (1) PH26882A (enExample)
PL (1) PL149733B1 (enExample)
PT (1) PT83094B (enExample)
SE (1) SE8603252L (enExample)
SG (1) SG8789G (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11511101A (ja) * 1995-08-23 1999-09-28 エヌピーケー インダストリアル デザイン ビーヴィ ブリスタパックからピルを取り出すための装置

Families Citing this family (525)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1272917A (en) * 1985-07-30 1990-08-21 Paul Kenneth Rand Devices for administering medicaments to patients
IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli
US4817789A (en) * 1987-09-23 1989-04-04 Allergan, Inc. Lens container assembly
FR2626500B1 (fr) * 1988-01-28 1990-04-27 Valois Sa Poussoir de vaporisateur agence pour operer le melange d'un additif dans l'emission du jet
CH678151A5 (en) * 1988-07-13 1991-08-15 Heinz Hermann Weick Self-medication nasal dispenser
GB8824804D0 (en) * 1988-10-22 1988-11-30 Fisons Plc Device
SE466684B (sv) * 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5239991A (en) * 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
US5270305A (en) * 1989-09-08 1993-12-14 Glaxo Group Limited Medicaments
US5208226A (en) * 1989-09-08 1993-05-04 Glaxo Group Limited Medicaments
DK544589D0 (da) * 1989-11-01 1989-11-01 Novo Nordisk As Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
HU213221B (en) * 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
UA26230A (uk) 1990-03-02 1999-07-19 Глексо Груп Лімітед Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
GB9012870D0 (en) * 1990-06-08 1990-08-01 Glaxo Group Ltd Device
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
IT1243344B (it) * 1990-07-16 1994-06-10 Promo Pack Sa Inalatore plurimonodose per medicamenti in polvere
SE9002895D0 (sv) * 1990-09-12 1990-09-12 Astra Ab Inhalation devices for dispensing powders i
US5429122A (en) * 1990-09-26 1995-07-04 Zanen; Pieter Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
NL9002706A (nl) * 1990-12-10 1992-07-01 Pharmachemie Bv Inrichting ten gebruike bij het inhaleren van in staafvormige capsules verpakte poedervormige stoffen.
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
EP0940154B1 (en) * 1991-07-02 2007-04-18 Nektar Therapeutics Device for delivering aerosolized medicaments
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5287850A (en) * 1991-08-20 1994-02-22 Habley Medical Technology Corporation Timing and velocity controlled powered pharmaceutical inhaler
DE4128295A1 (de) * 1991-08-27 1993-03-04 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer fliessfaehige medien
GB9124468D0 (en) * 1991-11-18 1992-01-08 Smithkline Beecham Plc Novel device
USD350821S (en) 1991-11-18 1994-09-20 Smithkline Beecham P.L.C. Oral inhaler
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
GB2264237A (en) * 1992-02-05 1993-08-25 Robert Edward Newell An inhaler
GB9203761D0 (en) * 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
EP0558879B1 (en) * 1992-03-04 1997-05-14 Astra Aktiebolag Disposable inhaler
US5301664A (en) * 1992-03-06 1994-04-12 Sievers Robert E Methods and apparatus for drug delivery using supercritical solutions
JPH0633935Y2 (ja) * 1992-03-27 1994-09-07 サカセ化学工業株式会社 グルーピングメディシンプール
DE9307115U1 (de) * 1992-05-29 1993-09-02 GGU Gesellschaft für Gesundheits- und Umweltforschung mbH & Co. Vertriebs KG, 65933 Frankfurt Vorrichtung zur Erzeugung inhalierbarer Wirkstoffe
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6673335B1 (en) * 1992-07-08 2004-01-06 Nektar Therapeutics Compositions and methods for the pulmonary delivery of aerosolized medicaments
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
HU216405B (hu) * 1993-03-03 1999-06-28 Tenax Corp. Hordozóelem por alakú gyógyszerek adagolására szolgáló inhalálókészülékhez
TW360548B (en) 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
US5372128A (en) * 1993-04-14 1994-12-13 Habley Medical Technology Corporation Fluidizing powder inhaler
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
BE1007408A3 (nl) * 1993-08-13 1995-06-06 Winters Joep Werkwijze en inrichting voor het controleren van het gebruik van een geneesmiddel.
US5524613A (en) * 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
PT101450B (pt) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
HUT75676A (en) * 1994-03-07 1997-05-28 Inhale Therapeutic Syst Methods and compositions for pulmonary delivery of insulin
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
GB9409851D0 (en) * 1994-05-17 1994-07-06 Cambridge Consultants Improvements in and relating to containers of particulate material
JPH10500672A (ja) * 1994-05-18 1998-01-20 インヘイル セラピューティック システムズ，インコーポレイティド インターフェロンの乾燥粉末製剤に関する方法及び組成物
US5483954A (en) * 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US6290991B1 (en) * 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
RU2146153C1 (ru) * 1994-09-21 2000-03-10 Инхейл Терапьютик Системз Устройство и способ распыления лекарственных средств в виде сухого порошка (варианты)
FR2725626A1 (fr) * 1994-10-18 1996-04-19 Sofab Dispositif pour l'inhalation de produits en poudre
DE19500764C2 (de) * 1995-01-13 2001-09-27 Sofotec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
US5676643A (en) * 1995-02-13 1997-10-14 The Procter & Gamble Company Dispenser for friably releasing dry particulate medicaments
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5714007A (en) 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
US5669973A (en) * 1995-06-06 1997-09-23 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing and retaining materials upon a substrate
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5642727A (en) * 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
US5988163A (en) * 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US5692496A (en) * 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5823183A (en) * 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US6209538B1 (en) 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5649554A (en) * 1995-10-16 1997-07-22 Philip Morris Incorporated Electrical lighter with a rotatable tobacco supply
US5827985A (en) * 1995-12-19 1998-10-27 Endress + Hauser Gmbh + Co. Sensor apparatus for process measurement
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
DE69618624T2 (de) 1996-01-03 2002-08-08 Glaxo Group Ltd., Greenford Inhaliervorrichtung
USD381416S (en) * 1996-02-08 1997-07-22 Astra Aktiebolag Unit dose inhaler
USD395499S (en) 1996-04-08 1998-06-23 Dura Pharmaceuticals, Inc. Dry powder inhaler
AU134061S (en) 1996-04-11 1998-06-16 Glaxo Group Ltd Inhalation device
US5743251A (en) 1996-05-15 1998-04-28 Philip Morris Incorporated Aerosol and a method and apparatus for generating an aerosol
GB9610821D0 (en) * 1996-05-23 1996-07-31 Glaxo Wellcome Inc Metering apparatus
US5857456A (en) * 1996-06-10 1999-01-12 Sarnoff Corporation Inhaler apparatus with an electronic means for enhanced release of dry powders
US5871010A (en) * 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
GB9616047D0 (en) 1996-07-31 1996-09-11 Glaxo Group Ltd Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof
US20030203036A1 (en) * 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
US6077543A (en) 1996-12-31 2000-06-20 Inhale Therapeutic Systems Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
US5794613A (en) * 1997-01-09 1998-08-18 Sepracor, Inc. Multiple-dose dispenser for dry powder inhalers
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
US6237590B1 (en) * 1997-09-18 2001-05-29 Delsys Pharmaceutical Corporation Dry powder delivery system apparatus
USD417731S (en) * 1997-10-22 1999-12-14 The Procter & Gamble Company Container for nasal spray
DE69840876D1 (de) * 1997-12-02 2009-07-16 Valois Sas Trockenpulverinhalator
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
USD412978S (en) 1997-12-02 1999-08-17 Dura Pharmaceuticals, Inc. Inhaler
US6116238A (en) * 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
AU750539B2 (en) * 1998-03-16 2002-07-18 Novartis Ag Aerosolized active agent delivery
DE19817417A1 (de) * 1998-04-18 1999-10-21 Pfeiffer Erich Gmbh & Co Kg Spender für Medien, insbesondere Pulver
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
US6149774A (en) 1998-06-10 2000-11-21 Delsys Pharmaceutical Corporation AC waveforms biasing for bead manipulating chucks
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
KR100522910B1 (ko) * 1998-09-15 2005-12-21 주식회사 새 한 청량감이 우수한 폴리에스테르 가연가공사의 제조방법
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US6234167B1 (en) * 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
US6923979B2 (en) 1999-04-27 2005-08-02 Microdose Technologies, Inc. Method for depositing particles onto a substrate using an alternating electric field
BR0011343A (pt) * 1999-06-05 2002-03-12 Innovata Biomed Ltd Dispositivo de distribuição de medicamento,e,métodos de administrar um medicamento por inalação,e de,tratamento de um paciente com distúrbio respiratório
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US6730066B1 (en) 1999-08-03 2004-05-04 Pharmacia Ab Liquid delivery container
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
GB9924415D0 (en) * 1999-10-16 1999-12-15 Glaxo Group Ltd Medicament pack
AU1752601A (en) * 1999-11-11 2001-06-06 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6810872B1 (en) 1999-12-10 2004-11-02 Unisia Jecs Corporation Inhalant medicator
US20010029947A1 (en) 1999-12-17 2001-10-18 Steve Paboojian Receptacles to facilitate the extraction of powders
US6883516B2 (en) 2000-04-27 2005-04-26 Chrysalis Technologies Incorporated Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution
MY136453A (en) * 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
US6948494B1 (en) * 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
GB0015034D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Inhalation device
TWI224515B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd Pre-metered dose magazine for breath-actuated dry powder inhaler
US7575761B2 (en) * 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
EP1172122A1 (en) * 2000-07-14 2002-01-16 The Technology Partnership Public Limited Company Dry powder inhaler
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
EP1305329B2 (en) 2000-08-05 2015-03-18 Glaxo Group Limited 6.alpha.,9.alpha.-difluoro-17.alpha.-(2-furanylcarboxyl)oxy-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4-diene-17-carbothioic acid s-fluoromethyl ester as an anti-inflammatory agent
WO2002013886A2 (en) * 2000-08-15 2002-02-21 University Of Kentucky Research Foundation Programmable multi-dose intranasal drug delivery device
SE517229C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Kontinuerlig inhalator för torrt pulver
GB0023654D0 (en) 2000-09-27 2000-11-08 Cambridge Consultants Device for administering doses of particulate material
US6595210B2 (en) 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6701921B2 (en) 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US7077130B2 (en) 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US6799572B2 (en) 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
BR0207062A (pt) * 2001-02-06 2004-10-05 Innovata Biomed Ltd Composição farmacêutica bimodal, inalador para pó seco, método de aplicação de uma quantidade terapeuticamente eficaz de um ingrediente ativo substancialmente fino aos pulmões de um paciente, método de tratamento de um distúrbio respiratório, método de tratamento de doença pulmonar obstrutiva crÈnica (copd), uso de um agente antiinflamatório, uso de um broncodilatador, uso de uma mistura de um agente antiinflamatório e de um broncodilatador, e, processo para a fabricação de uma composição farmacêutica bimodal
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
WO2002076933A1 (en) 2001-03-22 2002-10-03 Glaxo Group Limited Formailide derivatives as beta2-adrenoreceptor agonists
EP1381417A4 (en) 2001-04-26 2009-12-30 New England Pharm Inc DEVICE FOR RELEASING SATISFIED DOSHES OF LIQUID AND POWDERY MEDIUM
EP2039700A2 (en) 2001-04-30 2009-03-25 Glaxo Group Limited Novel anti-inflammatory androstane derivatives
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
US8061006B2 (en) 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US6540081B2 (en) * 2001-09-06 2003-04-01 Ecolab Inc. Unit dose blister pack product dispenser
DE60230425D1 (de) 2001-09-14 2009-01-29 Glaxo Group Ltd Phenethanolamin-derivate zur behandlung von erkrankungen der atemwege
US8337816B2 (en) 2001-09-17 2012-12-25 Glaxo Group Limited Dry powder medicament formulations
US6871647B2 (en) 2001-09-19 2005-03-29 Advent Pharmaceuticals Pty Ltd Inhaler
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
WO2003041777A1 (en) * 2001-11-14 2003-05-22 Nektar Therapeutics Aerosolization device with improved endpiece connection
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6804458B2 (en) * 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
US7458373B2 (en) 2002-01-15 2008-12-02 Philip Morris Usa Inc. Aerosol generator for drug formulation
JP2005527260A (ja) * 2002-01-25 2005-09-15 グラクソ　グループ　リミテッド 薬剤ディスペンサ
GB0217199D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
GB0201677D0 (en) * 2002-01-25 2002-03-13 Glaxo Group Ltd Medicament dispenser
US20060187750A1 (en) * 2002-03-01 2006-08-24 Victor Aldrich Rotary blending apparatus and system
WO2003078448A1 (en) 2002-03-13 2003-09-25 Signum Biosciences, Inc. Modulation of protein methylation and phosphoprotein phosphate
DE10212264A1 (de) 2002-03-20 2003-10-02 Boehringer Ingelheim Pharma Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
DE60318938T2 (de) 2002-03-20 2009-01-22 Mannkind Corp., Valencia Inhalationsgerät
EP1487716A4 (en) * 2002-03-26 2008-05-21 Glaxo Group Ltd METHOD FOR PRODUCING A LAMINATE ARRANGEMENT AND PRODUCTS THEREOF PRODUCED
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
DE10216429A1 (de) 2002-04-12 2003-10-23 Boehringer Ingelheim Pharma Arzneimittel enthaltend Steroide und ein neues Anticholinergikum
GB0208608D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Composition
GB0208609D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Compositions
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
EP1497261B1 (en) * 2002-04-25 2007-12-19 Glaxo Group Limited Phenethanolamine derivatives
JP2005524134A (ja) * 2002-04-25 2005-08-11 グラクソ　グループ　リミテッド 環境条件を検知するための磁気音響センサーシステムおよびそれに関連する方法
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US6854461B2 (en) * 2002-05-10 2005-02-15 Philip Morris Usa Inc. Aerosol generator for drug formulation and methods of generating aerosol
JP2005526261A (ja) * 2002-05-15 2005-09-02 グラクソ　グループ　リミテッド 医薬包装内の温度および水分プロファイルを測定するための微小電気機械システムおよび方法
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
EP1707205A2 (en) 2002-07-09 2006-10-04 Boehringer Ingelheim Pharma GmbH & Co. KG Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases
DE10230751A1 (de) 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und EGFR-Kinase-Hemmern
US20050251289A1 (en) * 2002-07-25 2005-11-10 Bonney Stanley G Medicament dispenser
GB0217196D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
GB0217198D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
JP2005533581A (ja) * 2002-07-25 2005-11-10 グラクソ　グループ　リミテッド 薬剤ディスペンサ
ES2357566T3 (es) * 2002-09-06 2011-04-27 Philip Morris Usa Inc. Dispositivos generadores de aerosol y métodos para generar aerosoles con tamaños de partículas controlados.
US20070139442A1 (en) * 2002-09-13 2007-06-21 Robinson Karl E Coated blending system
US6962266B2 (en) * 2002-10-04 2005-11-08 Ecolab Inc. Method and apparatus for using a unit dose dispenser
EP1554264B1 (en) * 2002-10-22 2007-08-08 Glaxo Group Limited Medicinal arylethanolamine compounds
US6772757B2 (en) 2002-10-25 2004-08-10 Chrysalis Technologies Incorporated Concentric controlled temperature profile fluid vaporizing device
ATE390407T1 (de) 2002-10-28 2008-04-15 Glaxo Group Ltd Phenethanolamin-derivate zur behandlung von atemwegserkrankungen
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
AU2003293361A1 (en) * 2002-12-18 2004-07-29 Glaxo Group Limited Drug delivery system with vented mouthpiece
US6941947B2 (en) * 2002-12-18 2005-09-13 Quadrant Technologies Limited Unit dose dry powder inhaler
WO2004066912A2 (en) * 2003-01-31 2004-08-12 Technion Research & Development Foundation Ltd. Anti-inflammatory compositions and uses thereof
US20060251656A1 (en) * 2003-02-11 2006-11-09 Boehringer Ingelheim International Gmbh New pharmaceutical compositions based on anticholinergics and anti-tnf antibodies
WO2004071522A1 (en) * 2003-02-11 2004-08-26 Boehringer Ingelheim International Gmbh New pharmaceutical compositions based on anticholinergics and soluble tnf receptor fusion proteins
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
GB0303396D0 (en) 2003-02-14 2003-03-19 Glaxo Group Ltd Medicinal compounds
DE10317461A1 (de) 2003-04-16 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
US20040245279A1 (en) * 2003-05-05 2004-12-09 Bradley Tareasa L. System for dispensing an active ingredient using a dispensable tablet, dispensable tablet and container for holding such dispensable tablets
TW200510298A (en) 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
EP1488819A1 (en) * 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Dry powder inhaler and method for pulmonary inhalation of dry powder
GB0315509D0 (en) * 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
GB0316335D0 (en) * 2003-07-11 2003-08-13 Glaxo Group Ltd Pharmaceutical formulations
AR045914A1 (es) 2003-07-17 2005-11-16 Glaxo Group Ltd Compuesto alcoholico terciario del 8-azoniabiciclo [3.2.1] octano, composicion farmaceutica que lo comprende y su uso para preparar esta ultima
GB0317374D0 (en) 2003-07-24 2003-08-27 Glaxo Group Ltd Medicament dispenser
AU2004262902B2 (en) 2003-07-29 2009-07-30 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising betamimetics and an anticholinergic
US7367334B2 (en) 2003-08-27 2008-05-06 Philip Morris Usa Inc. Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6991131B2 (en) * 2003-09-02 2006-01-31 Ecolab, Inc. Distributable container and system and method using distributable container
AU2004273547B2 (en) * 2003-09-24 2006-07-06 Tianda Pharmaceuticals (Australia) Pty Ltd Medication holder
EP1675636A4 (en) * 2003-09-24 2009-12-23 Medi Stream Pty Ltd MEDICATION HOLDER
PL1677795T3 (pl) 2003-10-14 2011-05-31 Glaxo Group Ltd Antagoniści receptora muskarynowego acetylocholiny
GB2407042B (en) * 2003-10-17 2007-10-24 Vectura Ltd Inhaler
JP2007509061A (ja) 2003-10-17 2007-04-12 グラクソ　グループ　リミテッド ムスカリン性アセチルコリン受容体アンタゴニスト
GB0324654D0 (en) * 2003-10-22 2003-11-26 Glaxo Group Ltd Medicinal compounds
GB0324886D0 (en) * 2003-10-24 2003-11-26 Glaxo Group Ltd Medicinal compounds
GB0324897D0 (en) * 2003-10-24 2003-11-26 Glaxo Group Ltd Composition
WO2005044173A1 (en) * 2003-10-27 2005-05-19 Oriel Therapeutics, Inc. Blister packages and associated methods of fabricating dry powder drug containment systems
WO2005044187A2 (en) * 2003-10-28 2005-05-19 Glaxo Group Limited Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same
GB0325627D0 (en) * 2003-11-03 2003-12-10 Glaxo Group Ltd A hand-held capsule device
SI1682541T1 (sl) 2003-11-03 2010-06-30 Boehringer Ingelheim Int Postopek za pripravo tiotropijevih soli
UA82414C2 (uk) 2003-11-03 2008-04-10 Бёрингер Ингельхайм Интернациональ Гмбх Солі тіотропію, спосіб їх одержання, а також лікарські композиції, які їх містять
AR046225A1 (es) 2003-11-04 2005-11-30 Glaxo Group Ltd Compuesto de 8-azoniabiciclo(3.2.1)octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos que lo comprende y uso del compuesto para preparar dicha composicion
GB0329182D0 (en) * 2003-12-17 2004-01-21 Glaxo Group Ltd Chemical compounds
US8147426B2 (en) * 2003-12-31 2012-04-03 Nipro Diagnostics, Inc. Integrated diagnostic test system
GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
TWI341836B (en) 2004-03-11 2011-05-11 Theravance Inc Biphenyl compounds useful as muscarinic receptor antagonists
WO2005095407A1 (en) 2004-03-17 2005-10-13 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
BRPI0509382A (pt) * 2004-04-02 2007-09-18 Glaxo Group Ltd processo para a preparação de um sal monocloridrato de composto, monocloridrato cristalino, processo para obter monocloridrato cristalino, método para a profilaxia ou o tratamento de uma condição clìnica em um mamìfero, uso de monocloridrato cristalino, formulação farmacêutica, e, combinação
EP1744800B1 (en) * 2004-04-21 2016-06-22 Innovata Biomed Limited Inhaler
SI1781298T1 (sl) 2004-04-22 2012-04-30 Boehringer Ingelheim Int Farmacevtske kombinacije, ki vsebujejo benzoksazine, za zdravljenje respiratornih obolenj
US20050272726A1 (en) * 2004-04-22 2005-12-08 Boehringer Ingelheim International Gmbh Novel medicaments for the treatment of respiratory diseases
US7861712B2 (en) * 2004-04-23 2011-01-04 Manta Product Development Sealed capsule including an integrated puncturing mechanism
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
MY144753A (en) 2004-04-27 2011-10-31 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
US7723306B2 (en) * 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
US7611709B2 (en) * 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
US7727962B2 (en) * 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
JP2007537261A (ja) 2004-05-13 2007-12-20 グラクソ　グループ　リミテッド ムスカリン性アセチルコリン受容体アンタゴニスト
US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
WO2005110519A1 (en) * 2004-05-17 2005-11-24 Sun Pharmaceutical Industries Limited Dry powder inhaler
SE530006C2 (sv) * 2004-06-18 2008-02-05 Mederio Ag Inhalator som använder balja
US7896195B2 (en) * 2004-06-08 2011-03-01 Ecolab Inc. Tablet dispenser with isolated product hopper
US20050283106A1 (en) * 2004-06-17 2005-12-22 Shane Smith Reusable support device with therapeutic inserts
US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
US20060079544A1 (en) * 2004-08-13 2006-04-13 Boehringer Ingelheim International Gmbh Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
GB0418278D0 (en) * 2004-08-16 2004-09-15 Glaxo Group Ltd Medicament dispenser
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
GB0418738D0 (en) * 2004-08-23 2004-09-22 3M Innovative Properties Co Medicinal aerosol formulation receptacle and production thereof
CA2578175C (en) 2004-08-23 2014-10-14 Mannkind Corporation Diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery
WO2006047663A2 (en) * 2004-10-26 2006-05-04 The University Of North Carolina At Chapel Hill Aerosol generation of therapeutic agents
JP2006130143A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 吸入式投薬器及び薬剤カートリッジ
US20060120972A1 (en) * 2004-11-09 2006-06-08 Peter Engels 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension
WO2006053059A2 (en) * 2004-11-12 2006-05-18 Glaxo Group Limited Sensor system with acoustic transducer
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
MX344036B (es) 2004-11-24 2016-12-02 Meda Pharmaceuticals Inc Composiciones que comprenden azelastina y metodos de uso de la misma.
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
GB0427858D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0427856D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Maniflod for use in medicament dispenser
GB0427853D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
WO2006074897A1 (en) * 2005-01-11 2006-07-20 Glaxo Group Limited Cinnamate salts of a beta-2 adrenergic agonist
CA2601777A1 (en) * 2005-02-03 2006-08-10 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
MX2007009656A (es) 2005-02-10 2007-11-07 Glaxo Group Ltd Proceso para elaborar lactosa utilizando tecnicas de clasificacion previa y formulaciones farmaceuticas formadas de la misma.
US20090029901A1 (en) * 2005-02-10 2009-01-29 Marian Wood-Kaczmar Process for Crystallizing Lactose Particles for Use in Pharmaceutical Formulations
UY29440A1 (es) 2005-03-25 2006-10-02 Glaxo Group Ltd Nuevos compuestos
TW200724142A (en) 2005-03-25 2007-07-01 Glaxo Group Ltd Novel compounds
GB0507711D0 (en) 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
US9585932B2 (en) 2005-04-29 2017-03-07 Peter C. Dowling Use of EPO-derived peptide fragments for the treatment of neurodegenerative disorders
US8653028B2 (en) 2005-04-29 2014-02-18 Rui Rong Yuan Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
US9345745B2 (en) 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
EP2085396A3 (en) 2005-05-02 2009-11-25 Boehringer Ingelheim International Gmbh Novel crystalline forms of tiotropium bromide
AU2006247053B2 (en) 2005-05-18 2013-05-23 Horizon Therapeutics U.S. Holding Llc Aerosolized fluoroquinolones and uses thereof
US8524734B2 (en) * 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
JP2008543806A (ja) * 2005-06-17 2008-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療のためのｍｒｐｉｖインヒビター
DE102005030733A1 (de) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
US20070012316A1 (en) * 2005-07-14 2007-01-18 Joann Truza Disposable compact rescue inhaler
GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
GB0515584D0 (en) * 2005-07-28 2005-09-07 Glaxo Group Ltd Medicament dispenser
GB0516168D0 (en) * 2005-08-05 2005-09-14 Cambridge Lab Ireland Ltd Pharmaceutical compounds
PL1917253T3 (pl) * 2005-08-15 2015-06-30 Boehringer Ingelheim Int Sposób wytwarzania betamimetyków
WO2007022351A2 (en) 2005-08-18 2007-02-22 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
US20090192227A1 (en) * 2005-08-24 2009-07-30 Rabindra Tirouvanziam N-Acetylcysteine Compositions and Methods for Treating Acute Exacerbations of Inflammatory Lung Disease
US20070049641A1 (en) * 2005-08-24 2007-03-01 Rabindra Tirouvanziam Methods for treating and monitoring inflammation and redox imbalance cystic fibrosis
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
US8227408B2 (en) * 2005-09-07 2012-07-24 Neurotez, Inc. Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology
US7481331B2 (en) * 2005-09-09 2009-01-27 Manrex Limited Dispensing container for a blister pack of medications
RU2390325C2 (ru) 2005-09-14 2010-05-27 Маннкайнд Корпорейшн Способ приготовления лекарственного препарата, основанный на увеличении сродства активных агентов к поверхностям кристаллических микрочастиц
TWI396541B (zh) 2005-10-10 2013-05-21 Boehringer Ingelheim Int 用於治療呼吸疾病之新穎藥物組合
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
DE102005057685A1 (de) * 2005-12-01 2007-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Speicher für eine trockene Arzneimittelformulierung sowie diesbezügliche Verfahren und Verwendung
AR058289A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
DE102005059602A1 (de) 2005-12-14 2007-06-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Mikronisierung
CN104383546B (zh) 2006-02-22 2021-03-02 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
JP5188991B2 (ja) * 2006-03-03 2013-04-24 エスティーシー．ユーエヌエム 空力弾性分配メカニズムを有するドライパウダー吸入器
US8127763B2 (en) * 2006-03-03 2012-03-06 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
EP1844808A1 (de) * 2006-04-13 2007-10-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medikamenten-Ausgabevorrichtung
EP1844805A1 (de) * 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co.KG Inhalator
PT103481B (pt) 2006-05-16 2008-08-01 Hovione Farmaciencia S A Inalador de uso simples e método de inalação
WO2007137233A1 (en) 2006-05-19 2007-11-29 Valspar Sourcing, Inc. Coating system for cement composite articles
JP2009543658A (ja) * 2006-07-14 2009-12-10 アストラゼネカ・アクチエボラーグ 乾燥粉末状の薬を投与するための吸入装置及び配送装置
US20090324510A1 (en) 2006-08-07 2009-12-31 Boehringer Ingelheim International Gmbh Drug combinations for the treatment of respiratory tract diseases
UY30552A1 (es) * 2006-08-22 2008-03-31 Boehringer Ingelheim Int Combinaciones farmacologiicas en base a derivados sustituidos de la n-(5-{2-[1,1-dimetil-propilamino]-1-hidroxi-metil}-2-hidroxi-fenil)-metansulfonamida y aplicaciones
DE102006045788A1 (de) * 2006-09-26 2008-03-27 Alfred Von Schuckmann Spender für pulverförmige Massen
CA2667225C (en) 2006-10-25 2015-06-09 Novartis Ag Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
GB0622827D0 (en) * 2006-11-15 2006-12-27 Glaxo Group Ltd Sheet driver for use in a drug dispenser
EP1925295A1 (de) 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
ES2594281T3 (es) 2007-01-10 2016-12-19 Purdue Research Foundation Inhibidores polipeptídicos de HSP27 quinasa y usos de los mismos
PE20081889A1 (es) 2007-03-23 2009-03-05 Smithkline Beecham Corp Indol carboxamidas como inhibidores de ikk2
US20080237082A1 (en) * 2007-03-29 2008-10-02 R. P. Scherer Technologies, Inc. Child resistant device for housing blister packs
AT505246B8 (de) * 2007-06-01 2009-06-15 Croma Pharma Gmbh Container für eine mehrzahl von einzeldosen sowie applikator für derartige container
CN101795723B (zh) 2007-07-06 2013-06-19 蒙塔设备有限公司 用于存储和输送药物的吸入装置
US11224704B2 (en) 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
EP2185698B1 (en) 2007-08-07 2015-04-22 Purdue Research Foundation Kinase inhibitors and uses thereof
EP2093219A1 (de) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
BRPI0909187A2 (pt) * 2008-03-20 2015-08-04 Virun Inc Emulsões incluindo tocoferol de derivados de peg
MX2010010214A (es) * 2008-03-20 2010-12-21 Virun Inc Derivados de vitamina e y sus usos.
KR20110028457A (ko) * 2008-05-21 2011-03-18 뉴로테즈 인코포레이티드 신경섬유 매듭과 연관된 신경변성 장애를 치료하는 방법
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
CA2982550C (en) 2008-06-13 2020-08-25 Mannkind Corporation A dry powder inhaler and system for drug delivery
DK2609954T3 (da) 2008-06-20 2022-02-14 Mannkind Corp Interaktivt apparat til realtidsafbildning af inhalationspræstationer
WO2010008475A2 (en) * 2008-06-23 2010-01-21 Virun, Inc. Compositions containing nono-polar compounds
JP5339794B2 (ja) * 2008-07-04 2013-11-13 キヤノン株式会社 吸入装置
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
GB2463451A (en) 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
CA2732840C (en) 2008-09-26 2016-07-05 Oriel Therapeutics, Inc. Dry powder inhalers with dual piercing members and related devices and methods
WO2010036355A2 (en) * 2008-09-26 2010-04-01 Oriel Therapeutics, Inc. Inhaler mechanisms with radially biased piercers and related methods
KR101311977B1 (ko) 2008-09-26 2013-09-26 오리엘 테라퓨틱스, 인크. 분리된 공기통로 채널들을 갖는 공기통로 디스크들 및 관련된 디스크들을 구비한 흡입기 및 이와 관련된 방법
WO2010039201A2 (en) * 2008-09-30 2010-04-08 Oriel Therapeutics, Inc. Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods
ES2561899T3 (es) * 2008-10-01 2016-03-01 Oriel Therapeutics, Inc. Inhaladores de polvo seco con mecanismos de perforación giratorios y dispositivos y métodos relacionados
US8629139B2 (en) 2008-10-07 2014-01-14 Mpex Pharmaceuticals, Inc. Topical use of Levofloxacin for reducing lung inflammation
BRPI0920026B1 (pt) 2008-10-07 2023-11-07 Horizon Orphan Llc Composição farmacêutica e respectivos usos
ES2507496T3 (es) * 2008-10-20 2014-10-15 Moerae Matrix, Inc. Polipéptido para tratar o evitar adherencias
AU2009313562B2 (en) * 2008-11-04 2012-11-15 Neurotez, Inc. Leptin compositions and methods for treating progressive cognitive function disorders resulting from accumulation of neurofibrillary tangles and amlyoid beta
EP2378875B1 (en) * 2008-12-10 2018-05-30 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8550074B2 (en) * 2009-01-15 2013-10-08 Manta Devices, Llc Delivery device and related methods
GB0901520D0 (en) 2009-01-30 2009-03-11 Vectura Delivery Devices Ltd Inhaler
CN104523661A (zh) 2009-02-06 2015-04-22 南加利福尼亚大学 含有单萜的治疗组合物
JP2012517405A (ja) 2009-02-09 2012-08-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器及び胃腸の疾患の治療のための新規医薬組成物
HUE067290T2 (hu) 2009-02-26 2024-10-28 Glaxo Group Ltd 4-{(1 R)-2-[(6-{2-[(2,6-diklórbenzil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2-(hidroxi-metil)fenolt tartalmazó gyógyszerkészítmények
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
MX357919B (es) * 2009-03-13 2018-07-25 Nucitec Sa De Cv Composición farmacéutica para el tratamiento de la hipercolesterolemia.
WO2010108046A1 (en) 2009-03-18 2010-09-23 Mannkind Corporation Inhaler adaptor for a laser diffraction apparatus and method for measuring particle size distribution
US8551528B2 (en) 2009-06-12 2013-10-08 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
JP2012530140A (ja) 2009-06-16 2012-11-29 メルク・シャープ・アンド・ドーム・コーポレーション グルココルチコイド受容体アゴニストとしての新規［３，２−ｃ］ヘテロアリールステロイド、組成物およびこの使用
EP2451787B1 (en) 2009-07-06 2013-04-24 Boehringer Ingelheim International GmbH Polymorph of [4,6-bis(dimethylamino)-2-(4-{[4-(trifluoromethyl)benzoyl]amino}benzyl)pyrimidin-5-yl]
EP2987490B1 (en) 2009-07-15 2017-06-14 Theravance Biopharma R&D IP, LLC Crystalline freebase forms of a biphenyl compound
SG178086A1 (en) 2009-07-24 2012-03-29 Amazentis Sa Compounds, compositions and methods for protecting brain health in neurodegenerative disorders
US9890195B2 (en) * 2009-07-27 2018-02-13 Purdue Research Foundation MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
PT2473170T (pt) 2009-09-04 2019-08-23 Horizon Orphan Llc Utilização de levofloxacina em aerossol para tratamento de fibrose cística
CN102573886A (zh) * 2009-09-17 2012-07-11 相互制药公司 用抗病毒剂治疗哮喘的方法
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CA2779488A1 (en) 2009-11-12 2011-05-19 Stc.Unm Dry powder inhaler with flutter dispersion member
US20110294828A1 (en) 2009-11-24 2011-12-01 Boehringer Ingelheim International Gmbh Process for preparing a polymorph of the choline salt of a pyrimidin-5-yl acetic acid derivative
WO2011066147A2 (en) 2009-11-24 2011-06-03 Boehringer Ingelheim International Gmbh Novel salt forms of pyrimidin-5-yl acetic acid derivative
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
US10210216B2 (en) * 2009-12-18 2019-02-19 Sybase, Inc. Dynamic attributes for mobile business objects
US8507734B2 (en) 2010-03-03 2013-08-13 Neonc Technologies Inc. Pharmaceutical compositions comprising monoterpenes
WO2011116293A2 (en) 2010-03-19 2011-09-22 Manta Devices, Llc Delivery device and related methods
EP2563164B1 (en) 2010-03-23 2016-06-29 Virun, Inc. Nanoemulsion including sucrose fatty acid ester
USD635246S1 (en) 2010-03-26 2011-03-29 Oriel Therapeutics, Inc. Dose disk for dry powder inhalers
USD641076S1 (en) 2010-03-26 2011-07-05 Oriel Therapeutics, Inc. Dry powder inhaler
WO2011162802A1 (en) 2010-06-21 2011-12-29 Virun, Inc. Compositions containing non-polar compounds
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
EP2883543B1 (en) 2010-08-27 2016-11-16 Neonc Technologies Inc. Pharmaceutical compositions comprising perillyl alcohol carbamates
US20160038600A1 (en) 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
EP3461474B1 (en) 2010-08-31 2020-11-11 GlaxoSmithKline Intellectual Property Development Limited Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
WO2012028663A1 (en) 2010-08-31 2012-03-08 Glaxo Group Limited Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
WO2012064286A1 (en) 2010-11-11 2012-05-18 Agency For Science, Technology And Research Targeting metabolic enzymes in human cancer
ES2646748T3 (es) 2010-12-07 2017-12-15 Respira Therapeutics, Inc. Inhalador de polvo seco
EP4656641A2 (en) 2010-12-17 2025-12-03 University of Southern California Methods and devices for using isoperillyl alcohol
CA2824432C (en) 2011-01-31 2021-10-19 Genoa Pharmaceuticals, Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
US9890200B2 (en) 2011-04-12 2018-02-13 Moerae Matrix, Inc. Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
CN108014340A (zh) 2011-04-12 2018-05-11 莫伊莱麦屈克斯公司 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病的组合物和方法
CN103717231B (zh) 2011-05-19 2016-08-17 萨瓦拉股份有限公司 干粉万古霉素组合物以及相关方法
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US8528569B1 (en) 2011-06-28 2013-09-10 Kyle D. Newton Electronic cigarette with liquid reservoir
US11103659B2 (en) 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
GB201116641D0 (en) 2011-09-27 2011-11-09 Glaxo Group Ltd Novel compounds
EP2776053A1 (en) 2011-10-24 2014-09-17 MannKind Corporation Methods and compositions for treating pain
EP2589381B1 (en) 2011-11-04 2016-08-31 Rabindra Tirouvanziam Compositions for improving or preserving lung function in a patient with a pulmonary disorder
US20150010527A1 (en) 2012-02-01 2015-01-08 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy
WO2013120025A1 (en) 2012-02-10 2013-08-15 Virun, Inc. Beverage compositions containing non-polar compounds
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
EP3421042B1 (en) 2012-03-07 2024-04-17 Beyond Air Ltd Inhalation of nitric oxide for treating respiratory diseases
WO2013134636A1 (en) 2012-03-09 2013-09-12 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
US9428452B2 (en) 2012-04-27 2016-08-30 Glaxo Group Limited Compounds
GB201207406D0 (en) 2012-04-27 2012-06-13 Glaxo Group Ltd Novel compounds
US9649454B2 (en) 2012-05-03 2017-05-16 Manta Devices, Llc Delivery device and related methods
WO2013176638A1 (en) 2012-05-25 2013-11-28 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi An inhaler comprising a mouthpiece having an improved air channel
JP6312262B2 (ja) 2012-07-12 2018-04-18 マンカインド コーポレイション 乾燥粉末薬物送達システム
CN105025904A (zh) 2012-09-04 2015-11-04 埃莱森制药有限责任公司 用顺铂脂质复合物预防癌症的肺部复发
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
SG11201503697TA (en) 2012-11-28 2015-06-29 Intercept Pharmaceuticals Inc Treatment of pulmonary disease
GB201301192D0 (en) 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
KR102391750B1 (ko) 2013-03-15 2022-04-28 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
DK177788B1 (en) 2013-07-12 2014-07-07 Liita Holdings Ltd Inhaler
CN105451716A (zh) 2013-07-18 2016-03-30 曼金德公司 热稳定性干粉药物组合物和方法
CA3172586C (en) 2013-07-31 2025-10-14 Avalyn Pharma Inc. IMATINIB AEROSOL COMPOUNDS AND RELATED USES
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
US9693574B2 (en) 2013-08-08 2017-07-04 Virun, Inc. Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
SG11201601850YA (en) 2013-09-10 2016-04-28 Univ Texas Therapeutics targeting truncated adenomatous polyposis coli (apc) proteins
US10039321B2 (en) 2013-11-12 2018-08-07 Vmr Products Llc Vaporizer
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
GB2560465B8 (en) 2013-12-23 2018-12-19 Juul Labs Uk Holdco Ltd Vaporization device systems and methods
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
USD769438S1 (en) * 2014-01-08 2016-10-18 Glaxo Group Limited Inhaler device
CA2936330C (en) 2014-01-10 2023-01-03 Genoa Pharmaceuticals Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
US10709173B2 (en) 2014-02-06 2020-07-14 Juul Labs, Inc. Vaporizer apparatus
US12279646B2 (en) 2014-02-06 2025-04-22 Juul Labs, Inc. Cartridge of vaporization device systems having unequal transverse cartridge dimensions
TWI751467B (zh) 2014-02-06 2022-01-01 美商尤爾實驗室有限公司 產生可吸入氣膠之裝置及用於該裝置之可分離匣
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10336788B2 (en) 2014-04-17 2019-07-02 Moerae Matrix, Inc. Inhibition of cardiac fibrosis in myocardial infarction
WO2015164142A1 (en) * 2014-04-24 2015-10-29 Questa Corporation Multi-size pill splitter and methods
WO2015168572A2 (en) * 2014-05-02 2015-11-05 Manta Devices, Llc Delivery device and related methods
SG11201609276RA (en) 2014-05-12 2016-12-29 Glaxosmithkline Ip No 2 Ltd Pharmaceutical compositions comprising danirixin for treating infectious diseases
US10940279B2 (en) * 2014-07-01 2021-03-09 Jennifer K. Keener Aromatherapy device
US10082496B2 (en) 2014-09-10 2018-09-25 Board Of Regents Of The University Of Texas System Targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
US10016363B2 (en) 2014-09-18 2018-07-10 Virun, Inc. Pre-spray emulsions and powders containing non-polar compounds
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US20170304459A1 (en) 2014-10-10 2017-10-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
CA2965759C (en) 2014-10-31 2023-12-12 Glaxosmithkline Intellectual Property Development Limited Powdered polypeptides with decreased disulfide impurities comprising divalent cationic materials
AU2015350151A1 (en) 2014-11-17 2017-06-01 Moerae Matrix, Inc. Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
EP3229831B1 (en) 2014-12-10 2020-03-11 Hyperstem SA Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors
US10087225B2 (en) 2015-01-08 2018-10-02 Moerae Matrix, Inc. Formulation of MK2 inhibitor peptides
CN107427650A (zh) 2015-01-14 2017-12-01 瑞必治公司 粉末分散方法和装置
EP3261441B1 (en) 2015-02-12 2020-09-09 Neonc Technologies Inc. Pharmaceutical compositions comprising perillyl alcohol derivatives
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
RU2017134274A (ru) 2015-03-11 2019-04-03 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Связывающие tslp белки
BR112017019343A2 (pt) 2015-03-12 2018-05-02 Moerae Matrix Inc uso de composições contendo peptídeo inibidor de mk2 para tratamento de câncer de pulmão de células não pequenas com as mesmas
US10179215B2 (en) 2015-03-19 2019-01-15 Altria Client Services Llc Vaporizer for vaporizing a constituent of a plant material
AU2016201131B2 (en) * 2015-03-30 2020-04-02 Manrex Limited Dispensing container for blister pack of medication
CA2987071A1 (en) 2015-06-10 2016-12-15 Hackensack University Medical Center Use of telmisartan to prevent and treat graft versus host disease and other alloimmune and autoimmune diseases
KR20180018684A (ko) 2015-06-15 2018-02-21 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 Nrf2 조절제
HUE066668T2 (hu) 2015-06-15 2024-08-28 Glaxosmithkline Intellectual Property Dev NRF2-szabályozók
JP2018517732A (ja) 2015-06-15 2018-07-05 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｎｒｆ２レギュレーター
WO2017007634A1 (en) 2015-07-06 2017-01-12 The Board Of Regents Of The University Of Texas System Benzamide or benzamine compounds useful as anticancer agents for the treatment of human cancers
DK3322417T3 (da) 2015-07-15 2023-10-30 Univ Texas Målretning af emopamil-bindingsprotein (EBP) med små molekyler, der inducerer et unormalt feedbackrespons ved sænkning af endogen cholesterolsyntese
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract
CN105013054B (zh) * 2015-07-30 2018-11-09 中山市美捷时包装制品有限公司 一种多胶囊型干粉吸入装置
CN104984448B (zh) * 2015-07-30 2018-05-01 中山市美捷时包装制品有限公司 一种干粉吸入器
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
EP3359532A1 (en) 2015-10-06 2018-08-15 GlaxoSmithKline Intellectual Property Development Limited Biaryl pyrazoles as nrf2 regulators
US10351530B2 (en) 2015-10-06 2019-07-16 Glaxosmithkline Intellectual Property Development Limited Arylcyclohexyl pyrazoles as NRF2 regulators
WO2017085692A1 (en) 2015-11-18 2017-05-26 Glaxosmithkline Intellectual Property (No.2) Limited Pharmaceutical compositions of ribavirin
US11833118B2 (en) 2016-01-20 2023-12-05 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispersible spray dried powders suitable for inhalation
US10328216B2 (en) 2016-01-20 2019-06-25 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispensible spray dried powders suitable for inhalation
USD861975S1 (en) 2016-02-08 2019-10-01 Juul Labs, Inc. Vaporizer device with cartridges
WO2017139595A1 (en) 2016-02-11 2017-08-17 Pax Labs, Inc. Fillable vaporizer cartridge and method of filling
CO2018009342A2 (es) 2016-02-11 2018-09-20 Juul Labs Inc Cartuchos de fijación segura para dispositivos vaporizadores
US11224705B2 (en) 2016-02-24 2022-01-18 Boehringer Ingelheim International Gmbh Inhaler
SG11201807028YA (en) 2016-02-25 2018-09-27 Juul Labs Inc Vaporization device control systems and methods
TW201825458A (zh) 2016-09-20 2018-07-16 英商葛蘭素史克智慧財產（第二）有限公司 Ｔｒｐｖ４拮抗劑
US10590077B2 (en) 2016-09-20 2020-03-17 Glaxosmithkline Intellectual Property Development Limited TRPV4 antagonists
AU2017330620A1 (en) 2016-09-20 2019-03-28 Glaxosmithkline Intellectual Property (No.2) Limited TRPV4 antagonists
DK3547836T3 (da) 2016-11-30 2024-11-18 Univ Southern California Perillylalkohol-3 brompyruvat-konjugat og fremgangsmåder til behandling af cancer
WO2018104766A1 (en) 2016-12-06 2018-06-14 Glaxosmithkline Intellectual Property Development Limited 3-(2,3-dihydro-1h-inden-5-yl)propanoic acid derivatives and their use as nrf2 regulators
US10426698B2 (en) * 2016-12-08 2019-10-01 Breeden Brothers, LLC Pill container with cap
JP2020500919A (ja) 2016-12-12 2020-01-16 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｎｒｆ２レギュレーターとしての３−カルボン酸ピロール
EP3551621A1 (en) 2016-12-12 2019-10-16 GlaxoSmithKline Intellectual Property Development Limited N-aryl pyrazoles as nrf2 regulators
WO2018109643A1 (en) 2016-12-14 2018-06-21 Glaxosmithkline Intellectual Property Development Limited Bisaryl heterocycles as nrf2 acti
ES2848699T3 (es) 2016-12-14 2021-08-11 Glaxosmithkline Ip Dev Ltd Compuestos de 3-oxo-1,4-diazepinilo como activadores de NRF2
ES2901617T3 (es) 2016-12-14 2022-03-23 Glaxosmithkline Ip Dev Ltd Bisarilamidas como reguladores de NRF2
ES2908941T3 (es) 2016-12-15 2022-05-04 Glaxosmithkline Ip Dev Ltd Triazoles unidos a éter como reguladores de NRF2
US11028099B2 (en) 2016-12-15 2021-06-08 Glaxosmithkline Intellectual Property Development Limited NRF2 activators
WO2018174938A1 (en) 2017-03-23 2018-09-27 Virun, Inc. Stable dry powders and emulsions containing probiotics and mucoadhesive protein
MY199746A (en) 2017-04-24 2023-11-21 Cocrystal Pharma Inc Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication
JP2021505636A (ja) 2017-12-11 2021-02-18 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ 急性肺傷害、急性呼吸促迫症候群および多臓器不全症候群の処置のためのｎｒｆ２アクチベーター
WO2019116231A1 (en) 2017-12-11 2019-06-20 Glaxosmithkline Intellectual Property Development Limited Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
GB201720989D0 (en) 2017-12-15 2018-01-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
AU2019208416B2 (en) 2018-01-17 2021-07-29 Glaxosmithkline Intellectual Property Development Limited PI4KIIIbeta inhibitors
WO2019157195A1 (en) 2018-02-08 2019-08-15 Neonc Technologies, Inc Methods of permeabilizing the blood brain barrier
EP3796906A1 (en) 2018-05-23 2021-03-31 GlaxoSmithKline Intellectual Property Management Limited Indanes as nrf2 activators
MX2021000917A (es) 2018-07-27 2021-06-23 Cocrystal Pharma Inc Derivados de pirrolo[2,3-b]piridina como inhibidores de la replicación del virus de la gripe.
ES2937837T3 (es) 2018-09-10 2023-03-31 Cocrystal Pharma Inc Inhibidores de piridopirazina y piridotriazina de la replicación del virus de la gripe
KR102890706B1 (ko) 2018-10-17 2025-11-24 코크리스탈 파마, 아이엔씨. 인플루엔자 바이러스 복제 억제제의 조합물
KR102873231B1 (ko) 2018-11-13 2025-10-17 코크리스탈 파마, 아이엔씨. 인플루엔자 치료제 제형
US20220048897A1 (en) 2018-11-26 2022-02-17 Cocrystal Pharma, Inc. Inhibitors of influenza virus replication
WO2020135920A1 (en) * 2018-12-28 2020-07-02 Université Libre de Bruxelles Kit for inhaled chemotherapy, and treatment of lung cancer with said kit
DE102020100551A1 (de) 2019-01-14 2020-07-16 Alfred Von Schuckmann Vorrichtung zum Inhalieren pulverförmiger Substanzen
DE102020100550A1 (de) * 2019-01-14 2020-07-16 Alfred Von Schuckmann Vorrichtung zum Inhalieren pulverförmiger Substanzen, Substanzbehälter für eine solche Vorrichtung sowie Verfahren zum Befüllen einer derartigen Vorrichtung
DE102019134285A1 (de) 2019-01-15 2020-07-16 Nuuvera Deutschland GmbH Vorrichtung und Verfahren zum Extrahieren und Aspirieren von Wirkstoffen, insbesondere aus der Cannabispflanze
CR20210515A (es) 2019-03-14 2022-03-28 Om Pharma Sa Extractos bacterianos estables como fármacos
CN113613665A (zh) 2019-03-14 2021-11-05 Om药物公司 治疗和/或预防哮喘、哮喘恶化、过敏性哮喘和/或与呼吸系统病症相关的微生物群相关的病症的方法
GB201908536D0 (en) 2019-06-13 2019-07-31 Glaxosmithkline Ip Dev Ltd Compounds
DE202019104547U1 (de) * 2019-08-19 2020-11-26 Rpc Formatec Gmbh Spender
USD943158S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer cartridge
USD943160S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
USD943159S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Component for a vaporizer cartridge
USD943161S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
US20230151034A1 (en) 2020-03-17 2023-05-18 Cocrystal Pharma, Inc. Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
US20230159453A1 (en) 2020-04-10 2023-05-25 Cocrystal Pharma, Inc. Inhibitors of norovirus and coronavirus replication
WO2021216547A1 (en) 2020-04-20 2021-10-28 Sorrento Therapeutics, Inc. Pulmonary administration of ace2 polypeptides
WO2022175425A1 (en) 2021-02-22 2022-08-25 Glaxosmithkline Intellectual Property Development Limited Inhaled mtor kinase inhibitors for use in the treatment or the prevention of a respiratory rna virus infection
WO2022179967A1 (en) 2021-02-23 2022-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Vadadustat for treating covid-19 in a hospitalized subject
JP2024521543A (ja) 2021-04-14 2024-06-03 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 蒸発／凝縮による治療用エアロゾルの生成のための高温多孔体計量のシステムおよび方法
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
TW202321196A (zh) 2021-08-03 2023-06-01 美商共結晶製藥公司 冠狀病毒抑制劑
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
JP2025513460A (ja) 2022-04-22 2025-04-24 クエンチ メディカル インコーポレイテッド 粉末吸入による医薬品の送達
WO2023232976A1 (en) 2022-06-03 2023-12-07 Ags Therapeutics Sas Extracellular vesicles from genetically-modified microalgae containing endogenously-loaded cargo, their preparation, and uses
WO2024095105A1 (de) * 2022-11-04 2024-05-10 Skietta Ag Vaporizer zur verdampfung eines inhalationsmediums

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB190707525A (en) * 1906-04-07 1907-11-28 Eugene Joseph Decoll Impovements relating to Appliances for Administering Anestetics
GB190706553A (en) * 1907-03-19 1907-11-28 Hume Purdie Surgical Apparatus for the Administration of Anaesthetics
US1383270A (en) * 1918-10-02 1921-06-28 Henning Albert Means for cooling internal-combustion engines and other machinery
US2386877A (en) * 1943-07-27 1945-10-16 Jr William E Neilson Box opener and dispenser
US3949751A (en) * 1970-03-03 1976-04-13 Fisons Limited Method and device for dispensing medicament to the body
US3888253A (en) * 1972-08-04 1975-06-10 Beecham Group Ltd Device for administration of medicines
GB1392945A (en) * 1972-08-23 1975-05-07 Fisons Ltd Inhalation device
GB1387954A (en) * 1973-05-08 1975-03-19 Miles Lab Insufflator
US4014336A (en) * 1975-01-13 1977-03-29 Syntex Puerto Rico, Inc. Inhalation device
GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
DE2834135C3 (de) * 1978-08-03 1981-11-26 SIEMENS AG AAAAA, 1000 Berlin und 8000 München Verfahren zum Herstellen einer Wanderfeldröhre
DE2835135C3 (de) * 1978-08-10 1982-03-04 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Wirkstoff-Speicher für ein Inhalationsgerät
IT1116047B (it) * 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
GB2061735B (en) * 1979-10-30 1983-11-30 Riker Laboratories Inc Breath actuated device for administration of powdered medicaments by inhalation
CH656311A5 (de) * 1979-10-30 1986-06-30 Riker Laboratories Inc Durch atemluft betaetigte vorrichtung zum oralen inhalieren eines medikamentes in pulverform.
EP0041783B1 (en) * 1980-06-06 1984-12-05 FISONS plc Inhalation device for powdered medicaments
ES506585A0 (es) * 1980-10-30 1982-09-01 Riker Laboratories Inc Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo
US4384649A (en) * 1980-12-11 1983-05-24 E. R. Squibb & Sons, Inc. Dispensing package
ES527304A0 (es) * 1981-03-27 1984-07-16 Erca Holding Un procedimiento para preparar derivados de pirimidona.
ZA837318B (en) * 1982-10-08 1985-06-26 Glaxo Group Ltd Device for administering medicaments to patients
PT77471B (en) * 1982-10-08 1986-08-19 Glaxo Group Ltd Devices for administering medicaments to patients
GB8314308D0 (en) * 1983-05-24 1983-06-29 Matburn Holdings Ltd Medical administration devices
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
CA1272917A (en) * 1985-07-30 1990-08-21 Paul Kenneth Rand Devices for administering medicaments to patients
US4690279A (en) * 1986-03-13 1987-09-01 Charles Hochberg Birth control pill dispenser in the form of a hair brush

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11511101A (ja) * 1995-08-23 1999-09-28 エヌピーケー インダストリアル デザイン ビーヴィ ブリスタパックからピルを取り出すための装置

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US5035237A (en) 1991-07-30

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