DE3682457D1 - Geraet zur verabreichung von medikamenten an patienten. - Google Patents

Geraet zur verabreichung von medikamenten an patienten.

Info

Publication number
DE3682457D1
DE3682457D1 DE8686305807T DE3682457T DE3682457D1 DE 3682457 D1 DE3682457 D1 DE 3682457D1 DE 8686305807 T DE8686305807 T DE 8686305807T DE 3682457 T DE3682457 T DE 3682457T DE 3682457 D1 DE3682457 D1 DE 3682457D1
Authority
DE
Germany
Prior art keywords
medicines
patients
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686305807T
Other languages
German (de)
English (en)
Inventor
Robert Edward Newell
Paul Kenneth Rand
Robert Alexander Fitzsimmons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26289568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3682457(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB858519141A external-priority patent/GB8519141D0/en
Priority claimed from GB858525067A external-priority patent/GB8525067D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE3682457D1 publication Critical patent/DE3682457D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Electrotherapy Devices (AREA)
  • Motorcycle And Bicycle Frame (AREA)
DE8686305807T 1985-07-30 1986-07-29 Geraet zur verabreichung von medikamenten an patienten. Expired - Lifetime DE3682457D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858519141A GB8519141D0 (en) 1985-07-30 1985-07-30 Administering medicaments to patients
GB858525067A GB8525067D0 (en) 1985-10-10 1985-10-10 Administering medicaments to patients

Publications (1)

Publication Number Publication Date
DE3682457D1 true DE3682457D1 (de) 1991-12-19

Family

ID=26289568

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8686305807T Expired - Lifetime DE3682457D1 (de) 1985-07-30 1986-07-29 Geraet zur verabreichung von medikamenten an patienten.
DE19863625685 Granted DE3625685A1 (de) 1985-07-30 1986-07-30 Geraet zum eingeben von medikamenten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19863625685 Granted DE3625685A1 (de) 1985-07-30 1986-07-30 Geraet zum eingeben von medikamenten

Country Status (35)

Country Link
US (2) US4811731A (enExample)
EP (1) EP0211595B1 (enExample)
JP (1) JPS6241668A (enExample)
KR (1) KR940002247B1 (enExample)
AT (1) AT396872B (enExample)
AU (1) AU591152B2 (enExample)
BE (1) BE905189A (enExample)
BR (1) BR8603576A (enExample)
CA (1) CA1272917A (enExample)
CH (1) CH672600A5 (enExample)
CY (1) CY1481A (enExample)
DE (2) DE3682457D1 (enExample)
DK (1) DK163640C (enExample)
DO (1) DOP1989004707A (enExample)
ES (1) ES2000781A6 (enExample)
FI (1) FI88112C (enExample)
FR (1) FR2585563B1 (enExample)
GB (1) GB2178965B (enExample)
GR (1) GR861995B (enExample)
HK (1) HK67589A (enExample)
HU (1) HU199306B (enExample)
IE (1) IE59026B1 (enExample)
IL (1) IL79550A (enExample)
IT (1) IT1195984B (enExample)
KE (1) KE3865A (enExample)
LU (1) LU86534A1 (enExample)
MX (1) MX171389B (enExample)
NL (1) NL8601949A (enExample)
NO (1) NO166268C (enExample)
NZ (1) NZ217006A (enExample)
PH (1) PH26882A (enExample)
PL (1) PL149733B1 (enExample)
PT (1) PT83094B (enExample)
SE (1) SE8603252L (enExample)
SG (1) SG8789G (enExample)

Families Citing this family (526)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2585563B1 (fr) * 1985-07-30 1993-11-12 Glaxo Group Ltd Dispositif pour administrer des medicaments a des patients
IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli
US4817789A (en) * 1987-09-23 1989-04-04 Allergan, Inc. Lens container assembly
FR2626500B1 (fr) * 1988-01-28 1990-04-27 Valois Sa Poussoir de vaporisateur agence pour operer le melange d'un additif dans l'emission du jet
CH678151A5 (en) * 1988-07-13 1991-08-15 Heinz Hermann Weick Self-medication nasal dispenser
GB8824804D0 (en) * 1988-10-22 1988-11-30 Fisons Plc Device
SE466684B (sv) * 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5239991A (en) * 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
US5208226A (en) * 1989-09-08 1993-05-04 Glaxo Group Limited Medicaments
US5270305A (en) * 1989-09-08 1993-12-14 Glaxo Group Limited Medicaments
DK544589D0 (da) * 1989-11-01 1989-11-01 Novo Nordisk As Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
YU48707B (sh) * 1990-03-02 1999-07-28 Glaxo Group Limited Aparat za inhaliranje - inhalator
SK280967B6 (sk) * 1990-03-02 2000-10-09 Glaxo Group Limited Inhalačný prístroj
GB9012870D0 (en) * 1990-06-08 1990-08-01 Glaxo Group Ltd Device
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
IT1243344B (it) * 1990-07-16 1994-06-10 Promo Pack Sa Inalatore plurimonodose per medicamenti in polvere
SE9002895D0 (sv) * 1990-09-12 1990-09-12 Astra Ab Inhalation devices for dispensing powders i
US5429122A (en) * 1990-09-26 1995-07-04 Zanen; Pieter Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
NL9002706A (nl) * 1990-12-10 1992-07-01 Pharmachemie Bv Inrichting ten gebruike bij het inhaleren van in staafvormige capsules verpakte poedervormige stoffen.
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
DE69230613T2 (de) * 1991-07-02 2000-12-28 Inhale Inc Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5287850A (en) * 1991-08-20 1994-02-22 Habley Medical Technology Corporation Timing and velocity controlled powered pharmaceutical inhaler
DE4128295A1 (de) * 1991-08-27 1993-03-04 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer fliessfaehige medien
GB9124468D0 (en) * 1991-11-18 1992-01-08 Smithkline Beecham Plc Novel device
USD350821S (en) 1991-11-18 1994-09-20 Smithkline Beecham P.L.C. Oral inhaler
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
GB2264237A (en) * 1992-02-05 1993-08-25 Robert Edward Newell An inhaler
GB9203761D0 (en) * 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
EP0558879B1 (en) * 1992-03-04 1997-05-14 Astra Aktiebolag Disposable inhaler
US5301664A (en) * 1992-03-06 1994-04-12 Sievers Robert E Methods and apparatus for drug delivery using supercritical solutions
JPH0633935Y2 (ja) * 1992-03-27 1994-09-07 サカセ化学工業株式会社 グルーピングメディシンプール
ES2118234T3 (es) * 1992-05-29 1998-09-16 Ggu Gesundheits Umweltforsch Dispositivo para generar particulas inhalables de sustancias activas.
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
US6673335B1 (en) * 1992-07-08 2004-01-06 Nektar Therapeutics Compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
BR9405842A (pt) * 1993-03-03 1996-01-16 Tenax Corp Portador de medicamento
TW404844B (en) * 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
US5372128A (en) * 1993-04-14 1994-12-13 Habley Medical Technology Corporation Fluidizing powder inhaler
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
BE1007408A3 (nl) * 1993-08-13 1995-06-06 Winters Joep Werkwijze en inrichting voor het controleren van het gebruik van een geneesmiddel.
US5524613A (en) * 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
PT101450B (pt) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
BR9507023A (pt) * 1994-03-07 1997-09-23 Inhale Therapeutic Syst Processos para aerossolização de uma dose de insulina para a liberação respiratória de insulina e para preparação de uma composição de insulina e composição de insulina
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
GB9409851D0 (en) * 1994-05-17 1994-07-06 Cambridge Consultants Improvements in and relating to containers of particulate material
AU696387B2 (en) * 1994-05-18 1998-09-10 Inhale Therapeutic Systems, Inc. Methods and compositions for the dry powder formulation of interferons
US5483954A (en) * 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
JP3706136B2 (ja) * 1994-09-21 2005-10-12 ネクター セラピューティクス 乾燥粉末薬剤の分散装置及び方法
FR2725626A1 (fr) * 1994-10-18 1996-04-19 Sofab Dispositif pour l'inhalation de produits en poudre
DE19500764C2 (de) * 1995-01-13 2001-09-27 Sofotec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
US5676643A (en) * 1995-02-13 1997-10-14 The Procter & Gamble Company Dispenser for friably releasing dry particulate medicaments
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5714007A (en) * 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
US5669973A (en) * 1995-06-06 1997-09-23 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing and retaining materials upon a substrate
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5642727A (en) * 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
US5692496A (en) * 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5823183A (en) * 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5988163A (en) * 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US6209538B1 (en) 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
NL1001031C1 (nl) * 1995-08-23 1997-02-25 Npk Ind Design B V Inrichting voor het afgeven van pillen uit een blisterverpakking.
US5649554A (en) * 1995-10-16 1997-07-22 Philip Morris Incorporated Electrical lighter with a rotatable tobacco supply
US5827985A (en) * 1995-12-19 1998-10-27 Endress + Hauser Gmbh + Co. Sensor apparatus for process measurement
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
JP2000503565A (ja) 1996-01-03 2000-03-28 グラクソ、グループ、リミテッド 吸入装置
USD381416S (en) * 1996-02-08 1997-07-22 Astra Aktiebolag Unit dose inhaler
USD395499S (en) 1996-04-08 1998-06-23 Dura Pharmaceuticals, Inc. Dry powder inhaler
AU134061S (en) 1996-04-11 1998-06-16 Glaxo Group Ltd Inhalation device
US5743251A (en) 1996-05-15 1998-04-28 Philip Morris Incorporated Aerosol and a method and apparatus for generating an aerosol
GB9610821D0 (en) * 1996-05-23 1996-07-31 Glaxo Wellcome Inc Metering apparatus
US5871010A (en) * 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
US5857456A (en) * 1996-06-10 1999-01-12 Sarnoff Corporation Inhaler apparatus with an electronic means for enhanced release of dry powders
GB9616047D0 (en) 1996-07-31 1996-09-11 Glaxo Group Ltd Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof
US20030203036A1 (en) * 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
JP2001507701A (ja) 1996-12-31 2001-06-12 インヘイル・セラピューティック・システムズ・インコーポレーテッド 親水性賦形剤を有する疎水性薬剤の溶液を噴霧乾燥するための方法及びその方法によって作製された組成物
US5794613A (en) * 1997-01-09 1998-08-18 Sepracor, Inc. Multiple-dose dispenser for dry powder inhalers
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
US6237590B1 (en) * 1997-09-18 2001-05-29 Delsys Pharmaceutical Corporation Dry powder delivery system apparatus
USD417731S (en) * 1997-10-22 1999-12-14 The Procter & Gamble Company Container for nasal spray
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
WO1999027987A1 (en) * 1997-12-02 1999-06-10 Dura Pharmaceuticals, Inc. Dry powder inhaler
USD412978S (en) 1997-12-02 1999-08-17 Dura Pharmaceuticals, Inc. Inhaler
US6116238A (en) * 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
EP1066074A1 (en) * 1998-03-16 2001-01-10 Inhale Therapeutic Systems, Inc. Aerosolized active agent delivery
DE19817417A1 (de) 1998-04-18 1999-10-21 Pfeiffer Erich Gmbh & Co Kg Spender für Medien, insbesondere Pulver
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
US6149774A (en) * 1998-06-10 2000-11-21 Delsys Pharmaceutical Corporation AC waveforms biasing for bead manipulating chucks
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
KR100522910B1 (ko) * 1998-09-15 2005-12-21 주식회사 새 한 청량감이 우수한 폴리에스테르 가연가공사의 제조방법
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
US6923979B2 (en) * 1999-04-27 2005-08-02 Microdose Technologies, Inc. Method for depositing particles onto a substrate using an alternating electric field
MXPA01012533A (es) * 1999-06-05 2003-10-14 Innovata Biomed Ltd Sistema de suministro.
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US6730066B1 (en) * 1999-08-03 2004-05-04 Pharmacia Ab Liquid delivery container
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
GB9924415D0 (en) * 1999-10-16 1999-12-15 Glaxo Group Ltd Medicament pack
AU1752601A (en) * 1999-11-11 2001-06-06 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6810872B1 (en) 1999-12-10 2004-11-02 Unisia Jecs Corporation Inhalant medicator
US6679256B2 (en) 1999-12-17 2004-01-20 Nektar Therapeutics Systems and methods for extracting powders from receptacles
MY136453A (en) * 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
US6883516B2 (en) * 2000-04-27 2005-04-26 Chrysalis Technologies Incorporated Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution
US6948494B1 (en) * 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
GB0015034D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Inhalation device
PE20020066A1 (es) * 2000-06-23 2002-02-23 Norton Healthcare Ltd Deposito de dosis medidas previamente para inhalador de polvo seco accionado por la respiracion
US7575761B2 (en) * 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
EP1172122A1 (en) * 2000-07-14 2002-01-16 The Technology Partnership Public Limited Company Dry powder inhaler
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
AU2001276497B2 (en) 2000-08-05 2005-04-07 Glaxo Group Limited 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents
JP2004505730A (ja) * 2000-08-15 2004-02-26 ユニバーシティ オブ ケンタッキー リサーチ ファウンデーション プログラム可能多用量鼻腔内薬物送達デバイス
SE517229C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Kontinuerlig inhalator för torrt pulver
GB0023654D0 (en) 2000-09-27 2000-11-08 Cambridge Consultants Device for administering doses of particulate material
US6595210B2 (en) 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
US7077130B2 (en) 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US6701921B2 (en) 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US6799572B2 (en) * 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
BR0207062A (pt) * 2001-02-06 2004-10-05 Innovata Biomed Ltd Composição farmacêutica bimodal, inalador para pó seco, método de aplicação de uma quantidade terapeuticamente eficaz de um ingrediente ativo substancialmente fino aos pulmões de um paciente, método de tratamento de um distúrbio respiratório, método de tratamento de doença pulmonar obstrutiva crÈnica (copd), uso de um agente antiinflamatório, uso de um broncodilatador, uso de uma mistura de um agente antiinflamatório e de um broncodilatador, e, processo para a fabricação de uma composição farmacêutica bimodal
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
JP4143413B2 (ja) 2001-03-22 2008-09-03 グラクソ グループ リミテッド β2−アドレナリン受容体アゴニストとしてのホルムアニリド誘導体
US7025058B2 (en) 2001-04-26 2006-04-11 New England Pharmaceuticals, Inc. Metered dose delivery device for liquid and powder agents
ATE411334T1 (de) 2001-04-30 2008-10-15 Glaxo Group Ltd Antiphlogistische 7.beta.-carbothioate esterderivate von androstan mit einer 17.alpha.- zyklischen estergruppe
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
US8061006B2 (en) * 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US6540081B2 (en) * 2001-09-06 2003-04-01 Ecolab Inc. Unit dose blister pack product dispenser
CN101701006B (zh) 2001-09-14 2014-03-05 葛兰素集团有限公司 治疗呼吸疾病的苯乙醇胺衍生物
JP2005507881A (ja) 2001-09-17 2005-03-24 グラクソ グループ リミテッド 乾燥粉末医薬製剤
JP4261351B2 (ja) 2001-09-19 2009-04-30 アドヴェント ファーマセウティカルズ プロプライエタリー リミテッド 吸入器
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
US20030094173A1 (en) * 2001-11-14 2003-05-22 Inhale Therapeutic Systems, Inc. Aerosolization device with improved endpiece connection
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US6804458B2 (en) 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
US7458373B2 (en) * 2002-01-15 2008-12-02 Philip Morris Usa Inc. Aerosol generator for drug formulation
GB0201677D0 (en) 2002-01-25 2002-03-13 Glaxo Group Ltd Medicament dispenser
GB0217199D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
JP2005527260A (ja) * 2002-01-25 2005-09-15 グラクソ グループ リミテッド 薬剤ディスペンサ
WO2003074164A1 (en) * 2002-03-01 2003-09-12 Glaxo Group Limited Rotary blending apparatus and system
EP1483283A4 (en) 2002-03-13 2007-04-11 Signum Biosciences Inc MODULATION OF PROTEIN METHYLATION AND PHOSPHOPROTEIN PHOSPHATE
DE10212264A1 (de) 2002-03-20 2003-10-02 Boehringer Ingelheim Pharma Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
SI1494732T1 (sl) 2002-03-20 2008-08-31 Mannking Corp Inhalacijski aparat
WO2003095332A1 (en) * 2002-03-26 2003-11-20 Glaxo Group Limited A method for forming a laminate assembly and products formed thereby
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
DE10216429A1 (de) 2002-04-12 2003-10-23 Boehringer Ingelheim Pharma Arzneimittel enthaltend Steroide und ein neues Anticholinergikum
GB0208609D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Compositions
GB0208608D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Composition
ATE381535T1 (de) * 2002-04-25 2008-01-15 Glaxo Group Ltd Phenethanolaminderivate
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
AU2003228683A1 (en) * 2002-04-25 2003-11-10 Glaxo Group Limited Magnetoacoustic sensor system and associated method for sensing environmental conditions
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
WO2003095005A1 (en) * 2002-05-10 2003-11-20 Chrysalis Technologies Incorporated Aerosol generator for drug formulation and methods of generating aerosol
US7089786B2 (en) * 2002-05-15 2006-08-15 Glaxo Group Limited Microelectromechanical system and method for determining temperature and moisture profiles within pharmaceutical packaging
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
EP1707205A2 (en) 2002-07-09 2006-10-04 Boehringer Ingelheim Pharma GmbH & Co. KG Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases
DE10230751A1 (de) 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und EGFR-Kinase-Hemmern
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
GB0217198D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
JP2005533582A (ja) * 2002-07-25 2005-11-10 グラクソ グループ リミテッド 薬剤ディスペンサ
GB0217196D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
US20050268908A1 (en) * 2002-07-25 2005-12-08 Bonney Stanley G Medicament dispenser
ES2357566T3 (es) 2002-09-06 2011-04-27 Philip Morris Usa Inc. Dispositivos generadores de aerosol y métodos para generar aerosoles con tamaños de partículas controlados.
EP1565256A4 (en) * 2002-09-13 2008-05-07 Glaxo Group Ltd COATED MIXING DEVICE
US6962266B2 (en) * 2002-10-04 2005-11-08 Ecolab Inc. Method and apparatus for using a unit dose dispenser
EP1554264B1 (en) * 2002-10-22 2007-08-08 Glaxo Group Limited Medicinal arylethanolamine compounds
US6772757B2 (en) 2002-10-25 2004-08-10 Chrysalis Technologies Incorporated Concentric controlled temperature profile fluid vaporizing device
WO2004037773A1 (en) 2002-10-28 2004-05-06 Glaxo Group Limited Phenethanolamine derivative for the treatment of respiratory diseases
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
US6941947B2 (en) * 2002-12-18 2005-09-13 Quadrant Technologies Limited Unit dose dry powder inhaler
AU2003293361A1 (en) * 2002-12-18 2004-07-29 Glaxo Group Limited Drug delivery system with vented mouthpiece
EP1587482A4 (en) * 2003-01-31 2010-08-25 Technion Res & Dev Foundation INFLAMMATORY COMPOSITIONS AND ITS USES
JP2006517215A (ja) * 2003-02-11 2006-07-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗コリン薬と可溶性tnf受容体融合タンパク質とを基にした新規な医薬組成物
EP1594540A1 (en) * 2003-02-11 2005-11-16 Boehringer Ingelheim International GmbH New pharmaceutical compositions based on anticholinergics and anti-tnf antibodies
GB0303396D0 (en) 2003-02-14 2003-03-19 Glaxo Group Ltd Medicinal compounds
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
DE10317461A1 (de) 2003-04-16 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
US20040245279A1 (en) * 2003-05-05 2004-12-09 Bradley Tareasa L. System for dispensing an active ingredient using a dispensable tablet, dispensable tablet and container for holding such dispensable tablets
TW200510298A (en) 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
EP1488819A1 (en) * 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Dry powder inhaler and method for pulmonary inhalation of dry powder
GB0315509D0 (en) * 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
GB0316335D0 (en) * 2003-07-11 2003-08-13 Glaxo Group Ltd Pharmaceutical formulations
AR045914A1 (es) 2003-07-17 2005-11-16 Glaxo Group Ltd Compuesto alcoholico terciario del 8-azoniabiciclo [3.2.1] octano, composicion farmaceutica que lo comprende y su uso para preparar esta ultima
GB0317374D0 (en) 2003-07-24 2003-08-27 Glaxo Group Ltd Medicament dispenser
EP1651270B1 (en) 2003-07-29 2007-03-21 Boehringer Ingelheim International GmbH Medicaments for inhalation comprising betamimetics and an anticholinergic
US7367334B2 (en) 2003-08-27 2008-05-06 Philip Morris Usa Inc. Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6991131B2 (en) * 2003-09-02 2006-01-31 Ecolab, Inc. Distributable container and system and method using distributable container
AU2004273547B2 (en) * 2003-09-24 2006-07-06 Tianda Pharmaceuticals (Australia) Pty Ltd Medication holder
CA2540179A1 (en) 2003-09-24 2005-03-31 Medi-Stream Pty Ltd Medication holder
SI1677795T1 (sl) 2003-10-14 2011-04-29 Glaxo Group Ltd Antagonisti muskarinskega acetilholinskega receptorja
PE20050442A1 (es) 2003-10-17 2005-07-09 Glaxo Group Ltd Derivados de 8-azoniabiciclo[3.2.1]octano como antagonistas de receptores muscarinicos de la acetilcolina
GB2407042B (en) 2003-10-17 2007-10-24 Vectura Ltd Inhaler
GB0324654D0 (en) * 2003-10-22 2003-11-26 Glaxo Group Ltd Medicinal compounds
GB0324886D0 (en) * 2003-10-24 2003-11-26 Glaxo Group Ltd Medicinal compounds
GB0324897D0 (en) * 2003-10-24 2003-11-26 Glaxo Group Ltd Composition
WO2005041848A2 (en) * 2003-10-27 2005-05-12 Oriel Therapeutics, Inc. Dry powder drug containment system packages with tabs, inhalers and associated methods
EP1686960A4 (en) * 2003-10-28 2007-03-07 Glaxo Group Ltd INHALABLE PHARMACEUTICAL PREPARATIONS EMPLOYING LACTOSE ANHYDRATE, AND METHODS OF ADMINISTERING SAID PREPARATIONS
JP5165245B2 (ja) 2003-11-03 2013-03-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規なチオトロピウム塩、その製造方法及びチオトロピウム塩を含有する医薬組成物
GB0325627D0 (en) * 2003-11-03 2003-12-10 Glaxo Group Ltd A hand-held capsule device
EP2336126A1 (de) 2003-11-03 2011-06-22 Boehringer Ingelheim International GmbH Tiotropiumsalze, Verfahren zu deren Herstellung und Arzneimittelformulierungen diese enthaltend
TW200524577A (en) 2003-11-04 2005-08-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
GB0329182D0 (en) 2003-12-17 2004-01-21 Glaxo Group Ltd Chemical compounds
US8147426B2 (en) * 2003-12-31 2012-04-03 Nipro Diagnostics, Inc. Integrated diagnostic test system
GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
TWI341836B (en) 2004-03-11 2011-05-11 Theravance Inc Biphenyl compounds useful as muscarinic receptor antagonists
EP1725564A4 (en) 2004-03-17 2007-09-12 Glaxo Group Ltd ANTAGONISTS OF THE M3 MUSCARIN ACETYL CHOLIN RECEPTOR
WO2005095328A1 (en) 2004-04-02 2005-10-13 Glaxo Group Limited Chemical process and new crystalline form
BRPI0509348A (pt) 2004-04-21 2007-09-11 Innovata Biomed Ltd inalador
KR101287460B1 (ko) 2004-04-22 2013-07-23 베링거 인겔하임 인터내셔날 게엠베하 벤즈옥사진을 함유하는 호흡기 질환 치료용 약제학적배합물
US20050272726A1 (en) * 2004-04-22 2005-12-08 Boehringer Ingelheim International Gmbh Novel medicaments for the treatment of respiratory diseases
US7861712B2 (en) 2004-04-23 2011-01-04 Manta Product Development Sealed capsule including an integrated puncturing mechanism
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
MY144753A (en) 2004-04-27 2011-10-31 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
US7611709B2 (en) * 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
US7727962B2 (en) * 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
US7723306B2 (en) * 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
WO2005112644A2 (en) 2004-05-13 2005-12-01 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
WO2005110519A1 (en) * 2004-05-17 2005-11-24 Sun Pharmaceutical Industries Limited Dry powder inhaler
SE530006C2 (sv) * 2004-06-18 2008-02-05 Mederio Ag Inhalator som använder balja
US7896195B2 (en) * 2004-06-08 2011-03-01 Ecolab Inc. Tablet dispenser with isolated product hopper
US20050283106A1 (en) * 2004-06-17 2005-12-22 Shane Smith Reusable support device with therapeutic inserts
US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
US20060079544A1 (en) * 2004-08-13 2006-04-13 Boehringer Ingelheim International Gmbh Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
GB0418278D0 (en) 2004-08-16 2004-09-15 Glaxo Group Ltd Medicament dispenser
JP5078014B2 (ja) 2004-08-20 2012-11-21 マンカインド コーポレイション ジケトピペラジン合成の触媒反応
GB0418738D0 (en) * 2004-08-23 2004-09-22 3M Innovative Properties Co Medicinal aerosol formulation receptacle and production thereof
JP4990142B2 (ja) 2004-08-23 2012-08-01 マンカインド コーポレイション 薬物送達のためのジケトピペラジン塩、ジケトモルホリン塩、又はジケトジオキサン塩
WO2006047663A2 (en) * 2004-10-26 2006-05-04 The University Of North Carolina At Chapel Hill Aerosol generation of therapeutic agents
JP2006130143A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 吸入式投薬器及び薬剤カートリッジ
US20060120972A1 (en) * 2004-11-09 2006-06-08 Peter Engels 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension
WO2006053059A2 (en) * 2004-11-12 2006-05-18 Glaxo Group Limited Sensor system with acoustic transducer
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
LT2522365T (lt) * 2004-11-24 2017-02-10 Meda Pharmaceuticals Inc. Kompozicijos, apimančios azelastiną, ir jų panaudojimo būdai
US20070020330A1 (en) * 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
GB0427856D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Maniflod for use in medicament dispenser
GB0427853D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0427858D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
CN101137625A (zh) * 2005-01-11 2008-03-05 葛兰素集团有限公司 β2肾上腺素能激动剂的肉桂酸盐
WO2006084033A1 (en) * 2005-02-03 2006-08-10 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
EP1848444B1 (en) 2005-02-10 2016-11-09 Glaxo Group Limited Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
JP2008529773A (ja) * 2005-02-10 2008-08-07 グラクソ グループ リミテッド 医薬製剤に使用するためのラクトース粒子の結晶化方法
TWI389690B (zh) 2005-03-25 2013-03-21 Glaxo Group Ltd 新穎化合物(一)
UY29439A1 (es) 2005-03-25 2006-10-02 Glaxo Group Ltd Nuevos compuestos
GB0507711D0 (en) 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
US8653028B2 (en) * 2005-04-29 2014-02-18 Rui Rong Yuan Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
US9585932B2 (en) 2005-04-29 2017-03-07 Peter C. Dowling Use of EPO-derived peptide fragments for the treatment of neurodegenerative disorders
US9345745B2 (en) 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
RU2417224C2 (ru) 2005-05-02 2011-04-27 Бёрингер Ингельхайм Интернациональ Гмбх Новые кристаллические формы тиотропийбромида
KR101488402B1 (ko) 2005-05-18 2015-02-03 엠펙스 파마슈티컬즈, 인코포레이티드 에어로졸화된 플루오로퀴놀론 및 이의 용도
US8546423B2 (en) * 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
JP2008543806A (ja) * 2005-06-17 2008-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療のためのmrpivインヒビター
DE102005030733A1 (de) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
US20070012316A1 (en) * 2005-07-14 2007-01-18 Joann Truza Disposable compact rescue inhaler
GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
GB0515584D0 (en) * 2005-07-28 2005-09-07 Glaxo Group Ltd Medicament dispenser
GB0516168D0 (en) * 2005-08-05 2005-09-14 Cambridge Lab Ireland Ltd Pharmaceutical compounds
PL1917253T3 (pl) 2005-08-15 2015-06-30 Boehringer Ingelheim Int Sposób wytwarzania betamimetyków
WO2007022351A2 (en) 2005-08-18 2007-02-22 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
CA2620123C (en) * 2005-08-24 2011-11-22 The Board Of Trustees Of The Leland Stanford Junior University Methods for treating and monitoring inflammation and redox imbalance in cystic fibrosis
US20090192227A1 (en) * 2005-08-24 2009-07-30 Rabindra Tirouvanziam N-Acetylcysteine Compositions and Methods for Treating Acute Exacerbations of Inflammatory Lung Disease
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
US8227408B2 (en) * 2005-09-07 2012-07-24 Neurotez, Inc. Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
US8716220B2 (en) * 2005-09-07 2014-05-06 Nikolaos Tezapsidis Leptin compositions and methods for treating progressive cognitive function disorders resulting from accumulation of neurofibrillary tangles and amyloid beta
US7481331B2 (en) * 2005-09-09 2009-01-27 Manrex Limited Dispensing container for a blister pack of medications
EP1937219B1 (en) 2005-09-14 2015-11-11 MannKind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
US20070086957A1 (en) 2005-10-10 2007-04-19 Thierry Bouyssou Combination of medicaments for the treatment of respiratory diseases
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
DE102005057685A1 (de) * 2005-12-01 2007-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Speicher für eine trockene Arzneimittelformulierung sowie diesbezügliche Verfahren und Verwendung
AR058289A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
DE102005059602A1 (de) 2005-12-14 2007-06-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Mikronisierung
CN104383546B (zh) 2006-02-22 2021-03-02 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
JP5188991B2 (ja) * 2006-03-03 2013-04-24 エスティーシー.ユーエヌエム 空力弾性分配メカニズムを有するドライパウダー吸入器
US8127763B2 (en) * 2006-03-03 2012-03-06 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
EP1844808A1 (de) * 2006-04-13 2007-10-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medikamenten-Ausgabevorrichtung
EP1844805A1 (de) * 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co.KG Inhalator
PT103481B (pt) 2006-05-16 2008-08-01 Hovione Farmaciencia S A Inalador de uso simples e método de inalação
EP2032664B1 (en) 2006-05-19 2017-11-08 Valspar Sourcing, Inc. Coating system for cement composite articles
JP2009543658A (ja) * 2006-07-14 2009-12-10 アストラゼネカ・アクチエボラーグ 乾燥粉末状の薬を投与するための吸入装置及び配送装置
DE502007006951D1 (de) 2006-08-07 2011-05-26 Boehringer Ingelheim Pharma Arzneimittelkombinationen zur behandlung von atemwegserkrankungen
UY30552A1 (es) * 2006-08-22 2008-03-31 Boehringer Ingelheim Int Combinaciones farmacologiicas en base a derivados sustituidos de la n-(5-{2-[1,1-dimetil-propilamino]-1-hidroxi-metil}-2-hidroxi-fenil)-metansulfonamida y aplicaciones
DE102006045788A1 (de) 2006-09-26 2008-03-27 Alfred Von Schuckmann Spender für pulverförmige Massen
WO2008051621A2 (en) 2006-10-25 2008-05-02 Novartis Ag Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
GB0622827D0 (en) * 2006-11-15 2006-12-27 Glaxo Group Ltd Sheet driver for use in a drug dispenser
EP1925295A1 (de) 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
EP2155228B1 (en) * 2007-01-10 2014-04-02 Purdue Research Foundation Polypeptide inhibitors of hsp27 kinase and uses therefor
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
US20080237082A1 (en) * 2007-03-29 2008-10-02 R. P. Scherer Technologies, Inc. Child resistant device for housing blister packs
AT505246B8 (de) * 2007-06-01 2009-06-15 Croma Pharma Gmbh Container für eine mehrzahl von einzeldosen sowie applikator für derartige container
CN101795723B (zh) 2007-07-06 2013-06-19 蒙塔设备有限公司 用于存储和输送药物的吸入装置
US11224704B2 (en) 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
DK2185698T3 (en) 2007-08-07 2015-07-27 Purdue Research Foundation Kinase Inhibitors and Uses thereof
EP2093219A1 (de) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
MX2010010050A (es) * 2008-03-20 2011-03-15 Virun Inc Star Emulsiones que incluyen un derivado de polietilen glicol de tocoferol.
CA2715018C (en) * 2008-03-20 2012-11-13 Virun, Inc. Vitamin e derivatives and their uses
AU2009248914A1 (en) * 2008-05-21 2009-11-26 Neurotez, Inc. Methods for Treating Neurodegenerative Disorders Related to Neurofibrillary Tangles
US9358352B2 (en) 2008-06-13 2016-06-07 Mannkind Corporation Dry powder drug delivery system and methods
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
CN109568740B (zh) 2008-06-13 2022-05-27 曼金德公司 干粉吸入器和用于药物输送的系统
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MX336361B (es) 2008-06-20 2015-12-03 Mannkind Corp Un metodo y un aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
WO2010008475A2 (en) * 2008-06-23 2010-01-21 Virun, Inc. Compositions containing nono-polar compounds
JP5339794B2 (ja) * 2008-07-04 2013-11-13 キヤノン株式会社 吸入装置
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
GB2463451A (en) 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
BRPI0919126B1 (pt) 2008-09-26 2021-07-27 Oriel Therapeutics, Inc Inalador de pó seco
KR101311977B1 (ko) 2008-09-26 2013-09-26 오리엘 테라퓨틱스, 인크. 분리된 공기통로 채널들을 갖는 공기통로 디스크들 및 관련된 디스크들을 구비한 흡입기 및 이와 관련된 방법
EP2346554B1 (en) * 2008-09-26 2015-09-16 Oriel Therapeutics, Inc. Inhaler mechanisms with radially biased piercers and related methods
WO2010039201A2 (en) * 2008-09-30 2010-04-08 Oriel Therapeutics, Inc. Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods
US8646446B2 (en) * 2008-10-01 2014-02-11 Oriel Therapeutics, Inc. Dry powder inhalers with rotating piercing mechanisms and related devices and methods
PT2344129T (pt) 2008-10-07 2018-04-23 Horizon Orphan Llc Formulações de fluoroquinolona em aerossol para farmacocinética melhorada
CA2739893C (en) 2008-10-07 2016-10-04 Mpex Pharmaceuticals, Inc. Inhalation of levofloxacin for reducing lung inflammation
KR20170001756A (ko) * 2008-10-20 2017-01-04 모레 매트릭스 인코포레이티드 유착 치료 또는 예방용 폴리펩티드
CN105920582B (zh) * 2008-12-10 2020-04-14 普渡研究基金会 基于细胞渗透性肽的激酶抑制剂
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8550074B2 (en) * 2009-01-15 2013-10-08 Manta Devices, Llc Delivery device and related methods
GB0901520D0 (en) 2009-01-30 2009-03-11 Vectura Delivery Devices Ltd Inhaler
EP3620154A1 (en) 2009-02-06 2020-03-11 University Of Southern California Therapeutic compositions comprising monoterpenes
WO2010089391A1 (en) 2009-02-09 2010-08-12 Boehringer Ingelheim International Gmbh New pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
EP4403231A3 (en) 2009-02-26 2024-10-23 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
EP2405963B1 (en) 2009-03-11 2013-11-06 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
PE20120647A1 (es) * 2009-03-13 2012-05-31 Nucitec Sa De Cv Composiciones y metodos para el tratamiento y prevencion de la enfermedad cardiovascular
KR20110139737A (ko) 2009-03-18 2011-12-29 맨카인드 코포레이션 레이저 회절 장치용의 흡입기 어댑터와 입도 분포 측정 방법
TWI547487B (zh) 2009-06-12 2016-09-01 曼凱公司 具限定比表面積之二酮基哌微粒子
AU2010260177A1 (en) 2009-06-16 2011-12-15 Merck Sharp & Dohme Corp. Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof
JP2012532191A (ja) 2009-07-06 2012-12-13 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング [4,6−ビス(ジメチルアミノ)−2−(4−{[4−(トリフルオロメチル)ベンゾイル]アミノ}ベンジル)ピリミジン−5−イル]の多形体
HRP20151344T1 (hr) 2009-07-15 2016-01-01 Theravance Biopharma R&D Ip, Llc Kristalni oblik slobodne baze bifenilnog spoja
EP2456772A4 (en) 2009-07-24 2013-02-27 Amazentis Sa COMPOUNDS, COMPOSITIONS AND METHODS FOR CONSERVING HEALTH HEALTH IN NEURODEEGENERATIVE DISEASES
WO2011017132A2 (en) * 2009-07-27 2011-02-10 Purdue Research, Foundation Mk2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
PL2473170T3 (pl) 2009-09-04 2020-03-31 Horizon Orphan Llc Zastosowanie lewofloksacyny w aerozolu do leczenia mukowiscydozy
US20110229437A1 (en) * 2009-09-17 2011-09-22 Mutual Pharmaceutical Company, Inc. Method of Treating Asthma with Antiviral Agents
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
EP2498848A2 (en) 2009-11-12 2012-09-19 Stc.Unm Dry powder inhaler with flutter dispersion member
US20110294828A1 (en) 2009-11-24 2011-12-01 Boehringer Ingelheim International Gmbh Process for preparing a polymorph of the choline salt of a pyrimidin-5-yl acetic acid derivative
EP2504318A2 (en) 2009-11-24 2012-10-03 Boehringer Ingelheim International GmbH Crystalline salt forms of a pyrimidin-5-yl acetic acid derivative
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
US10210216B2 (en) * 2009-12-18 2019-02-19 Sybase, Inc. Dynamic attributes for mobile business objects
BR112012022209A2 (pt) 2010-03-03 2017-06-06 Neonc Tech Inc composições farmacêuticas compreendendo monoterpenos
WO2011116293A2 (en) 2010-03-19 2011-09-22 Manta Devices, Llc Delivery device and related methods
CN103037708B (zh) 2010-03-23 2015-05-20 维尔恩公司 含有蔗糖脂肪酸酯的纳米乳液
USD635246S1 (en) 2010-03-26 2011-03-29 Oriel Therapeutics, Inc. Dose disk for dry powder inhalers
USD641076S1 (en) 2010-03-26 2011-07-05 Oriel Therapeutics, Inc. Dry powder inhaler
WO2011162802A1 (en) 2010-06-21 2011-12-29 Virun, Inc. Compositions containing non-polar compounds
JP5797755B2 (ja) 2010-08-27 2015-10-21 ネオンク テクノロジーズ インク. Poh誘導体を含む医薬組成物
US20160038600A1 (en) 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
JP5792307B2 (ja) 2010-08-31 2015-10-07 グラクソ グループ リミテッドGlaxo Group Limited 水分制御特性を示す乾燥粉末吸入薬物製品及びその投与方法
US20130157991A1 (en) 2010-08-31 2013-06-20 Osama Ahmed Aswania Dry Powder Inhalation Drug Products Exhibiting Moisture Control Properties and Methods of Administering the Same
US9297813B2 (en) 2010-11-11 2016-03-29 Agency For Science, Technology And Research Targeting metabolic enzymes in human cancer
JP6050758B2 (ja) 2010-12-07 2016-12-21 レスピラ セラピューティクス インコーポレイテッドRespira Therapeutics,Inc. 乾燥粉末吸入器及びその作動方法
EP4374929B1 (en) 2010-12-17 2025-09-03 University of Southern California Methods and devices for using isoperillyl alcohol
AU2012212269B2 (en) 2011-01-31 2016-05-19 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
SG10201606220QA (en) 2011-04-01 2016-09-29 Mannkind Corp Blister package for pharmaceutical cartridges
US9890200B2 (en) 2011-04-12 2018-02-13 Moerae Matrix, Inc. Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
SG10201604560TA (en) 2011-04-12 2016-07-28 Moerae Matrix Inc Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
SG195038A1 (en) 2011-05-19 2013-12-30 Savara Inc Dry powder vancomycin compositions and associated methods
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US8528569B1 (en) 2011-06-28 2013-09-10 Kyle D. Newton Electronic cigarette with liquid reservoir
US11103659B2 (en) 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
GB201116641D0 (en) 2011-09-27 2011-11-09 Glaxo Group Ltd Novel compounds
MX2014004983A (es) 2011-10-24 2014-09-22 Mannkid Corp Metodos y composiciones para tratar dolor.
EP2589381B1 (en) 2011-11-04 2016-08-31 Rabindra Tirouvanziam Compositions for improving or preserving lung function in a patient with a pulmonary disorder
EP2809780B1 (en) 2012-02-01 2018-05-02 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy
CA2863544C (en) 2012-02-10 2019-03-26 Virun, Inc. Beverage compositions containing non-polar compounds
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
EP2822566A4 (en) 2012-03-07 2015-08-05 Advanced Inhalation Therapies Ait Ltd INHALATION OF STICK OXIDE FOR THE TREATMENT OF RESPIRATORY DISEASES
US9452218B2 (en) 2012-03-09 2016-09-27 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
GB201207406D0 (en) 2012-04-27 2012-06-13 Glaxo Group Ltd Novel compounds
WO2013160418A1 (en) 2012-04-27 2013-10-31 Glaxo Group Limited Novel compounds
US9649454B2 (en) 2012-05-03 2017-05-16 Manta Devices, Llc Delivery device and related methods
WO2013176638A1 (en) 2012-05-25 2013-11-28 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi An inhaler comprising a mouthpiece having an improved air channel
SG10201605800UA (en) 2012-07-12 2016-09-29 Mannkind Corp Dry powder drug delivery system and methods
EP2892524B1 (en) 2012-09-04 2020-11-25 Eleison Pharmaceuticals, LLC Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
RU2693382C2 (ru) 2012-11-28 2019-07-02 Интерсепт Фармасьютикалз, Инк. Лечение заболевания дыхательной системы
GB201301192D0 (en) 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
DK177788B1 (en) 2013-07-12 2014-07-07 Liita Holdings Ltd Inhaler
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
EP3027026B1 (en) 2013-07-31 2024-11-13 Avalyn Pharma Inc. Aerosol tyrosine kinase inhibitor compounds and uses thereof
CN105517607A (zh) 2013-08-05 2016-04-20 曼金德公司 吹入设备和方法
US9693574B2 (en) 2013-08-08 2017-07-04 Virun, Inc. Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
ES2811090T3 (es) 2013-09-10 2021-03-10 Univ Texas Terapéuticos dirigidos a proteínas truncadas de poliposis adenomatosa coli (apc)
US10039321B2 (en) 2013-11-12 2018-08-07 Vmr Products Llc Vaporizer
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
PT3504991T (pt) 2013-12-23 2021-03-01 Juul Labs Int Inc Sistemas de dispositivo e métodos de vaporização
USD769438S1 (en) * 2014-01-08 2016-10-18 Glaxo Group Limited Inhaler device
JP7066321B2 (ja) 2014-01-10 2022-05-13 アヴァリン ファーマ インク. エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
US12279646B2 (en) 2014-02-06 2025-04-22 Juul Labs, Inc. Cartridge of vaporization device systems having unequal transverse cartridge dimensions
US10709173B2 (en) 2014-02-06 2020-07-14 Juul Labs, Inc. Vaporizer apparatus
TWI751467B (zh) 2014-02-06 2022-01-01 美商尤爾實驗室有限公司 產生可吸入氣膠之裝置及用於該裝置之可分離匣
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10336788B2 (en) 2014-04-17 2019-07-02 Moerae Matrix, Inc. Inhibition of cardiac fibrosis in myocardial infarction
JP6730931B2 (ja) * 2014-04-24 2020-07-29 クエスタ コーポレーション 複数サイズの丸薬分割器及び方法
EP3137140B1 (en) * 2014-05-02 2019-07-10 Manta Devices, LLC Delivery device
AU2015260841A1 (en) 2014-05-12 2016-12-01 Glaxosmithkline Intellectual Property (No. 2) Limited Pharmaceutical compositions comprising danirixin for treating infectious diseases
US10940279B2 (en) * 2014-07-01 2021-03-09 Jennifer K. Keener Aromatherapy device
US10082496B2 (en) 2014-09-10 2018-09-25 Board Of Regents Of The University Of Texas System Targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
US10016363B2 (en) 2014-09-18 2018-07-10 Virun, Inc. Pre-spray emulsions and powders containing non-polar compounds
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2016057693A1 (en) 2014-10-10 2016-04-14 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
AU2015338717B2 (en) 2014-10-31 2018-12-20 Glaxosmithkline Intellectual Property Development Limited Powder formulation
MX2017006372A (es) 2014-11-17 2017-08-21 Moerae Matrix Inc Composiciones y metodos para prevenir o tratar enfermedades, condiciones o procesos caracterizados por proliferacion de fibroblasto aberrante y matrix extracelular.
CA2970140A1 (en) 2014-12-10 2016-06-16 Hyperstem, SA Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors
WO2016112292A1 (en) 2015-01-08 2016-07-14 Moerae Matrix, Inc. Formulation of mk2 inhibitor peptides
CA2972826C (en) 2015-01-14 2023-09-12 Respira Therapeutics, Inc. Powder dispersion methods and devices
US9522918B2 (en) 2015-02-12 2016-12-20 Neonc Technologies, Inc. Pharmaceutical compositions comprising perillyl alcohol derivatives
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
BR112017019412A2 (pt) 2015-03-11 2018-05-02 Glaxosmithkline Ip Dev Ltd proteínas ligadoras de tslp
JP2018512401A (ja) 2015-03-12 2018-05-17 モイライ マトリックス インコーポレイテッド Mk2阻害剤ペプチド含有組成物を用いた非小細胞肺癌の治療を目的とするその使用
US10179215B2 (en) 2015-03-19 2019-01-15 Altria Client Services Llc Vaporizer for vaporizing a constituent of a plant material
AU2016201131B2 (en) * 2015-03-30 2020-04-02 Manrex Limited Dispensing container for blister pack of medication
EP3307069B1 (en) 2015-06-10 2021-08-04 Hackensack University Medical Center Use of telmisartan to prevent and treat graft versus host disease and other alloimmune and autoimmune diseases
ES2841574T3 (es) 2015-06-15 2021-07-08 Glaxosmithkline Ip Dev Ltd Reguladores NRF2
WO2016203401A1 (en) 2015-06-15 2016-12-22 Glaxosmithkline Intellectual Property Development Limited Nrf2 regulators
AU2016280235A1 (en) 2015-06-15 2017-12-14 Astex Therapeutics Limited Nrf2 regulators
US10112948B2 (en) 2015-07-06 2018-10-30 The Board Of Regents Of The University Of Texas System Benzamide or benzamine compounds useful as anticancer agents for the treatment of human cancers
CA2991420A1 (en) 2015-07-15 2017-01-19 The Board Of Regents Of The University Of Texas System Targeting emopamil binding protein (ebp) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract
CN104984448B (zh) * 2015-07-30 2018-05-01 中山市美捷时包装制品有限公司 一种干粉吸入器
CN105013054B (zh) * 2015-07-30 2018-11-09 中山市美捷时包装制品有限公司 一种多胶囊型干粉吸入装置
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物
JP2018529745A (ja) 2015-10-06 2018-10-11 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Nrf2レギュレーターとしてのビアリールピラゾール
WO2017060855A1 (en) 2015-10-06 2017-04-13 Glaxosmithkline Intellectual Property Development Limited Arylcyclohexyl pyrazoles as nrf2 regulators
RU2018120519A (ru) 2015-11-18 2019-12-18 ГлаксоСмитКлайн Интеллекчуал Проперти (N2) Лимитед Фармацевтические композиции рибавирина
US11833118B2 (en) 2016-01-20 2023-12-05 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispersible spray dried powders suitable for inhalation
WO2017127641A1 (en) 2016-01-20 2017-07-27 Flurry Powders Encapsulation of lipophilic ingredients in dispersible spray dried powders suitable for inhalation
USD861975S1 (en) 2016-02-08 2019-10-01 Juul Labs, Inc. Vaporizer device with cartridges
MX377347B (es) 2016-02-11 2025-03-07 Juul Labs Inc Cartucho rellenable de vaporizador y metodo de relleno
CO2018009342A2 (es) 2016-02-11 2018-09-20 Juul Labs Inc Cartuchos de fijación segura para dispositivos vaporizadores
JP7185529B2 (ja) * 2016-02-24 2022-12-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 吸入器
UA126061C2 (uk) 2016-02-25 2022-08-10 Джуул Лебз, Інк. Системи та способи керування випарним пристроєм
US10590077B2 (en) 2016-09-20 2020-03-17 Glaxosmithkline Intellectual Property Development Limited TRPV4 antagonists
TW201825458A (zh) 2016-09-20 2018-07-16 英商葛蘭素史克智慧財產(第二)有限公司 Trpv4拮抗劑
US11260049B2 (en) 2016-09-20 2022-03-01 Glaxosmithkline Intellectual Property (No. 2) Limited TRPV4 antagonists
EP3547836B1 (en) 2016-11-30 2024-08-21 University of Southern California A perillyl alcohol-3 bromopyruvate conjugate and methods of treating cancer
KR20190088404A (ko) 2016-12-06 2019-07-26 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 3-(2,3-디히드로-1h-인덴-5-일)프로판산 유도체 및 nrf2 조절제로서의 그의 용도
US10426698B2 (en) * 2016-12-08 2019-10-01 Breeden Brothers, LLC Pill container with cap
EP3551621A1 (en) 2016-12-12 2019-10-16 GlaxoSmithKline Intellectual Property Development Limited N-aryl pyrazoles as nrf2 regulators
EP3551620A1 (en) 2016-12-12 2019-10-16 GlaxoSmithKline Intellectual Property Development Limited 3-carboxylic acid pyrroles as nrf2 regulators
JP2020502129A (ja) 2016-12-14 2020-01-23 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Nrf2アクチベーターとしての3−オキソ−1,4−ジアゼピニル化合物
EP3555078B1 (en) 2016-12-14 2024-03-27 GlaxoSmithKline Intellectual Property Development Limited Bisaryl heterocycles as nrf2 activators
WO2018109647A1 (en) 2016-12-14 2018-06-21 Glaxosmithkline Intellectual Property Development Limited Bisaryl amides as nrf2 regulators
CA3044773A1 (en) 2016-12-15 2018-06-21 Glaxosmithkline Intellectual Property Development Limited Nrf2 activators
US11059816B2 (en) 2016-12-15 2021-07-13 Glaxosmithkline Intellectual Property Development Limited Ether linked triazoles as NRF2 activators
WO2018174938A1 (en) 2017-03-23 2018-09-27 Virun, Inc. Stable dry powders and emulsions containing probiotics and mucoadhesive protein
AU2018257778B2 (en) 2017-04-24 2022-02-17 Cocrystal Pharma, Inc. Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication
EP3723764A1 (en) 2017-12-11 2020-10-21 GlaxoSmithKline Intellectual Property Development Ltd Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
WO2019116231A1 (en) 2017-12-11 2019-06-20 Glaxosmithkline Intellectual Property Development Limited Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
GB201720989D0 (en) 2017-12-15 2018-01-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
TWI795510B (zh) 2018-01-17 2023-03-11 英商葛蘭素史密斯克藍智慧財產發展有限公司 PI4KIIIβ抑制劑
JP7325425B2 (ja) 2018-02-08 2023-08-14 ネオンク テクノロジーズ インク. 血液脳関門を透過性にする方法
WO2019224667A1 (en) 2018-05-23 2019-11-28 Glaxosmithkline Intellectual Property Development Limited Indanes as nrf2 activators
JP7522722B2 (ja) 2018-07-27 2024-07-25 コクリスタル ファーマ,インコーポレイテッド インフルエンザウイルス複製阻害剤としてのピロロ[2,3-b]ピリジン誘導体
JP7472108B2 (ja) 2018-09-10 2024-04-22 コクリスタル ファーマ,インコーポレイテッド ピリドピラジン系及びピリドトリアジン系インフルエンザウィルス複製阻害剤
ES2939148T3 (es) 2018-10-17 2023-04-19 Cocrystal Pharma Inc Combinaciones de inhibidores de la replicación del virus de la influenza
JP7706362B2 (ja) 2018-11-13 2025-07-11 コクリスタル ファーマ,インコーポレイテッド インフルエンザ治療薬の製剤
US20220048897A1 (en) 2018-11-26 2022-02-17 Cocrystal Pharma, Inc. Inhibitors of influenza virus replication
WO2020135920A1 (en) * 2018-12-28 2020-07-02 Université Libre de Bruxelles Kit for inhaled chemotherapy, and treatment of lung cancer with said kit
DE102020100550A1 (de) * 2019-01-14 2020-07-16 Alfred Von Schuckmann Vorrichtung zum Inhalieren pulverförmiger Substanzen, Substanzbehälter für eine solche Vorrichtung sowie Verfahren zum Befüllen einer derartigen Vorrichtung
DE102020100551A1 (de) 2019-01-14 2020-07-16 Alfred Von Schuckmann Vorrichtung zum Inhalieren pulverförmiger Substanzen
DE102019134285A1 (de) 2019-01-15 2020-07-16 Nuuvera Deutschland GmbH Vorrichtung und Verfahren zum Extrahieren und Aspirieren von Wirkstoffen, insbesondere aus der Cannabispflanze
KR20220006039A (ko) 2019-03-14 2022-01-14 옴 파르마 에스아 천식, 천식 악화, 알레르기성 천식 및/또는 호흡기 장애 관련 미생물총과 연관된 질환을 치료 및/또는 예방하는 방법
CN113840615A (zh) 2019-03-14 2021-12-24 Om药物公司 制备稳定细菌提取物的方法及其作为药物的用途
GB201908536D0 (en) 2019-06-13 2019-07-31 Glaxosmithkline Ip Dev Ltd Compounds
DE202019104547U1 (de) * 2019-08-19 2020-11-26 Rpc Formatec Gmbh Spender
USD943161S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
USD943158S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer cartridge
USD943160S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
USD943159S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Component for a vaporizer cartridge
WO2021188620A1 (en) 2020-03-17 2021-09-23 Cocrystal Pharma Inc. Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
MX2022012714A (es) 2020-04-10 2022-12-15 Cocrystal Pharma Inc Inhibidores de la replicacion de norovirus y coronavirus.
WO2021216547A1 (en) 2020-04-20 2021-10-28 Sorrento Therapeutics, Inc. Pulmonary administration of ace2 polypeptides
WO2022175425A1 (en) 2021-02-22 2022-08-25 Glaxosmithkline Intellectual Property Development Limited Inhaled mtor kinase inhibitors for use in the treatment or the prevention of a respiratory rna virus infection
WO2022179967A1 (en) 2021-02-23 2022-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Vadadustat for treating covid-19 in a hospitalized subject
AU2022258576A1 (en) 2021-04-14 2023-11-02 Research Triangle Institute Hot porous-solid metering systems and methods for generation of therapeutic aerosols by evaporation/condensation
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
KR20240055745A (ko) 2021-08-03 2024-04-29 코크리스탈 파마, 아이엔씨. 코로나바이러스 억제제
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
WO2023205389A1 (en) 2022-04-22 2023-10-26 Quench Medical Inc. Dry powder inhalation delivery of pharmaceuticals
WO2023232976A1 (en) 2022-06-03 2023-12-07 Ags Therapeutics Sas Extracellular vesicles from genetically-modified microalgae containing endogenously-loaded cargo, their preparation, and uses
WO2024095105A1 (de) * 2022-11-04 2024-05-10 Skietta Ag Vaporizer zur verdampfung eines inhalationsmediums

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB190707525A (en) * 1906-04-07 1907-11-28 Eugene Joseph Decoll Impovements relating to Appliances for Administering Anestetics
GB190706553A (en) * 1907-03-19 1907-11-28 Hume Purdie Surgical Apparatus for the Administration of Anaesthetics
US1383270A (en) * 1918-10-02 1921-06-28 Henning Albert Means for cooling internal-combustion engines and other machinery
US2386877A (en) * 1943-07-27 1945-10-16 Jr William E Neilson Box opener and dispenser
US3949751A (en) * 1970-03-03 1976-04-13 Fisons Limited Method and device for dispensing medicament to the body
US3888253A (en) * 1972-08-04 1975-06-10 Beecham Group Ltd Device for administration of medicines
GB1392945A (en) * 1972-08-23 1975-05-07 Fisons Ltd Inhalation device
GB1387954A (en) * 1973-05-08 1975-03-19 Miles Lab Insufflator
US4014336A (en) * 1975-01-13 1977-03-29 Syntex Puerto Rico, Inc. Inhalation device
GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
DE2834135C3 (de) * 1978-08-03 1981-11-26 SIEMENS AG AAAAA, 1000 Berlin und 8000 München Verfahren zum Herstellen einer Wanderfeldröhre
DE2835135C3 (de) * 1978-08-10 1982-03-04 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Wirkstoff-Speicher für ein Inhalationsgerät
IT1116047B (it) * 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
GB2061735B (en) * 1979-10-30 1983-11-30 Riker Laboratories Inc Breath actuated device for administration of powdered medicaments by inhalation
IE50472B1 (en) * 1979-10-30 1986-04-30 Riker Laboratories Inc Breath actuated devices for administering powdered medicaments
DE3167567D1 (en) * 1980-06-06 1985-01-17 Fisons Plc Inhalation device for powdered medicaments
ES506585A0 (es) * 1980-10-30 1982-09-01 Riker Laboratories Inc Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo
US4384649A (en) * 1980-12-11 1983-05-24 E. R. Squibb & Sons, Inc. Dispensing package
CA1198065A (fr) * 1981-03-27 1985-12-17 Roland Torterotot Procede et dispositif de percage d'un couvercle de recipient, et installation de fabrication du dispositif
GB2129691B (en) * 1982-10-08 1987-08-05 Glaxo Group Ltd Devices for administering medicaments to patients
ZA837318B (en) * 1982-10-08 1985-06-26 Glaxo Group Ltd Device for administering medicaments to patients
GB8314308D0 (en) * 1983-05-24 1983-06-29 Matburn Holdings Ltd Medical administration devices
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
FR2585563B1 (fr) * 1985-07-30 1993-11-12 Glaxo Group Ltd Dispositif pour administrer des medicaments a des patients
US4690279A (en) * 1986-03-13 1987-09-01 Charles Hochberg Birth control pill dispenser in the form of a hair brush

Also Published As

Publication number Publication date
CH672600A5 (enExample) 1989-12-15
DK360986D0 (da) 1986-07-29
GB2178965B (en) 1988-08-03
NO863062L (no) 1987-02-02
JPH0577433B2 (enExample) 1993-10-26
SE8603252D0 (sv) 1986-07-29
HK67589A (en) 1989-09-01
IE862022L (en) 1987-01-30
IL79550A0 (en) 1986-10-31
GB2178965A (en) 1987-02-25
PT83094A (pt) 1987-01-26
AU6065586A (en) 1987-02-12
DK360986A (da) 1987-01-31
KR940002247B1 (ko) 1994-03-19
BR8603576A (pt) 1987-03-04
AU591152B2 (en) 1989-11-30
PT83094B (pt) 1993-07-30
AT396872B (de) 1993-12-27
FR2585563B1 (fr) 1993-11-12
DOP1989004707A (es) 1997-10-17
ES2000781A6 (es) 1988-03-16
DK163640B (da) 1992-03-23
IE59026B1 (en) 1993-12-15
CY1481A (en) 1989-12-08
GB8618466D0 (en) 1986-09-03
PL149733B1 (en) 1990-03-31
HUT44182A (en) 1988-02-29
NL8601949A (nl) 1987-02-16
HU199306B (en) 1990-02-28
BE905189A (fr) 1987-01-29
EP0211595A3 (en) 1988-10-05
PL260858A1 (en) 1987-04-21
GR861995B (en) 1986-11-04
NO863062D0 (no) 1986-07-29
IT8648322A0 (it) 1986-07-29
DE3625685C2 (enExample) 1990-05-03
NZ217006A (en) 1989-04-26
FI863094A0 (fi) 1986-07-29
ATA204086A (de) 1993-05-15
DE3625685A1 (de) 1987-03-12
CA1272917A (en) 1990-08-21
EP0211595B1 (en) 1991-11-13
FI863094L (fi) 1987-01-31
EP0211595A2 (en) 1987-02-25
MX171389B (es) 1993-10-22
JPS6241668A (ja) 1987-02-23
FR2585563A1 (fr) 1987-02-06
IL79550A (en) 1991-06-10
IT1195984B (it) 1988-11-03
DK163640C (da) 1992-08-17
SG8789G (en) 1989-07-07
NO166268B (no) 1991-03-18
FI88112B (fi) 1992-12-31
US5035237A (en) 1991-07-30
KR870000937A (ko) 1987-03-10
LU86534A1 (fr) 1987-09-03
NO166268C (no) 1991-07-03
PH26882A (en) 1992-11-16
FI88112C (fi) 1993-04-13
SE8603252L (sv) 1987-01-31
KE3865A (en) 1989-05-19
US4811731A (en) 1989-03-14

Similar Documents

Publication Publication Date Title
DE3682457D1 (de) Geraet zur verabreichung von medikamenten an patienten.
IT8622683A0 (it) Dispositivo terapeutico per la somministrazione di medicamenti.
DE3789320D1 (de) Verabreichungsinstrument zum Einführen von festen Medikamenten.
DE3685094D1 (de) Pharmazeutisches praeparat zur kontrollierten freisetzung von wirkstoffen.
IT8267184A0 (it) Bendaggio per la somministrazione di medicamenti
BR8704283A (pt) Dispositivo de infusao de drogas
BR8606754A (pt) Dispositivo de distribuicao transcutanea de medicamento
DK233884D0 (da) Laegemiddeldoseringssystem
FI863077L (fi) Farmaceutisk dosenhet.
DE68909409D1 (de) Heilmitteldosierung zur verabreichung an fische.
DE3682229D1 (de) Zur stimulierung der traenensekretion verwendbare pharmazeutische praeparate.
FI860111A7 (fi) Terapeutiska medel.
DE3585722D1 (de) Geraet zur iontophoretischen verabreichung von medikamenten.
NO863625D0 (no) Medikamentdoseringsanordning.
FI863159A7 (fi) Sydänlääkkeinä käytettäviä heterosyklokarbonyyli- ja asetyylitiatsoloneja.
DE3782594D1 (de) Arzneimittel zur transdermalen verabreichung von nicorandil.
DE3688625D1 (de) Therapeutische bandage.
IT8520591A0 (it) Formulazione farmaceutica.
DE3877747D1 (de) Glasartige matrize zur verabreichung von heilmitteln.
DK681288D0 (da) Aenootropt terapeutisk laegemiddelae
DK469487A (da) Laegemiddel til behandling af fedme
KR870014091U (ko) 수간 약물 주입병
DE3483347D1 (de) Intravenoese heilmittelverabreichungsvorrichtung.
DK428287A (da) Nasalt farmaceutisk praeparat
ATE68975T1 (de) Zur stimulierung der traenensekretion verwendbare pharmazeutische praeparate.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition