ATE387925T1 - Vorrichtung und verfahren zum dispergieren von trockenen pulvermedikamenten - Google Patents

Vorrichtung und verfahren zum dispergieren von trockenen pulvermedikamenten

Info

Publication number
ATE387925T1
ATE387925T1 AT95932508T AT95932508T ATE387925T1 AT E387925 T1 ATE387925 T1 AT E387925T1 AT 95932508 T AT95932508 T AT 95932508T AT 95932508 T AT95932508 T AT 95932508T AT E387925 T1 ATE387925 T1 AT E387925T1
Authority
AT
Austria
Prior art keywords
feed tube
powder
receptacle
penetration
coupling
Prior art date
Application number
AT95932508T
Other languages
English (en)
Inventor
Adrian Smith
John Burr
Jeffrey Etter
George Axford
Shirley Lyons
Robert Platz
Original Assignee
Nektar Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/309,691 external-priority patent/US5785049A/en
Application filed by Nektar Therapeutics filed Critical Nektar Therapeutics
Application granted granted Critical
Publication of ATE387925T1 publication Critical patent/ATE387925T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A61M15/0036—Piercing means hollow piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0053—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal
    • A61M15/0055—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal the used dosages being coiled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0233—Conductive materials, e.g. antistatic coatings for spark prevention
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Nozzles (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT95932508T 1994-09-21 1995-09-15 Vorrichtung und verfahren zum dispergieren von trockenen pulvermedikamenten ATE387925T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/309,691 US5785049A (en) 1994-09-21 1994-09-21 Method and apparatus for dispersion of dry powder medicaments
US08/487,184 US5740794A (en) 1994-09-21 1995-06-07 Apparatus and methods for dispersing dry powder medicaments

Publications (1)

Publication Number Publication Date
ATE387925T1 true ATE387925T1 (de) 2008-03-15

Family

ID=26976958

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95932508T ATE387925T1 (de) 1994-09-21 1995-09-15 Vorrichtung und verfahren zum dispergieren von trockenen pulvermedikamenten

Country Status (18)

Country Link
US (3) US6089228A (de)
EP (1) EP0846009B1 (de)
JP (1) JP3706136B2 (de)
CN (2) CN1131080C (de)
AT (1) ATE387925T1 (de)
AU (1) AU697676B2 (de)
BR (1) BR9508964A (de)
CA (3) CA2555600C (de)
CZ (1) CZ289029B6 (de)
ES (1) ES2302332T3 (de)
FI (1) FI971173A0 (de)
HU (1) HU220472B1 (de)
IL (3) IL126325A (de)
NO (3) NO971316L (de)
NZ (2) NZ331353A (de)
PL (2) PL187750B1 (de)
RU (1) RU2146153C1 (de)
WO (1) WO1996009085A1 (de)

Families Citing this family (256)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
JP3706136B2 (ja) * 1994-09-21 2005-10-12 ネクター セラピューティクス 乾燥粉末薬剤の分散装置及び方法
US6019968A (en) * 1995-04-14 2000-02-01 Inhale Therapeutic Systems, Inc. Dispersible antibody compositions and methods for their preparation and use
US6165463A (en) 1997-10-16 2000-12-26 Inhale Therapeutic Systems, Inc. Dispersible antibody compositions and methods for their preparation and use
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
US6209538B1 (en) * 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5823179A (en) * 1996-02-13 1998-10-20 1263152 Ontario Inc. Nebulizer apparatus and method
PL185314B1 (pl) * 1996-04-25 2003-04-30 Astrazeneca Ab Inhalator
DE19637125A1 (de) * 1996-09-12 1998-03-19 Schuckmann Alfred Von Inhalier-Vorrichtung
WO1998029141A1 (en) 1996-12-31 1998-07-09 Inhale Therapeutic Systems, Inc. Processes for spray drying solutions of hydrophobic drugs with hydrophilic excipients and compositions prepared by such processes
SE9700424D0 (sv) * 1997-02-07 1997-02-07 Astra Ab Powder inhaler
DE19704849B4 (de) * 1997-02-08 2011-02-17 Ing. Erich Pfeiffer Gmbh Austragvorrichtung für Medien
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6192876B1 (en) 1997-12-12 2001-02-27 Astra Aktiebolag Inhalation apparatus and method
IL136881A0 (en) 1997-12-22 2001-06-14 Astrazeneca Ab Inhalation device
DE19757207A1 (de) 1997-12-22 1999-06-24 Alfred Von Schuckmann Vorrichtung zum Leersaugen pulverenthaltender Kavitäten
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
EA003196B1 (ru) * 1998-03-16 2003-02-27 Инхэл Терапьютик Системз, Инк Способ подачи действующего вещества в виде аэрозоля
DE19817417A1 (de) * 1998-04-18 1999-10-21 Pfeiffer Erich Gmbh & Co Kg Spender für Medien, insbesondere Pulver
GB9808802D0 (en) * 1998-04-24 1998-06-24 Glaxo Group Ltd Pharmaceutical formulations
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) * 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
WO2001026720A1 (en) * 1999-10-12 2001-04-19 Shl Medical Ab Inhaler
ES2343124T3 (es) 1999-10-29 2010-07-23 Novartis Ag Composiciones de polvo seco con dispersabilidad mejorada.
US7304750B2 (en) 1999-12-17 2007-12-04 Nektar Therapeutics Systems and methods for non-destructive mass sensing
US20010035184A1 (en) 1999-12-17 2001-11-01 Carlos Schuler Systems and methods for treating packaged powders
US6679256B2 (en) * 1999-12-17 2004-01-20 Nektar Therapeutics Systems and methods for extracting powders from receptacles
JP4777574B2 (ja) 2000-02-11 2011-09-21 レスピロニクス・レスピラトリー・ドラッグ・デリバリー・（ユーケー）・リミテッド 薬剤投与装置
US8820316B2 (en) 2000-02-11 2014-09-02 Respironics Respiratory Drug Delivery (Uk) Ltd Drug delivery apparatus
DE10011120A1 (de) 2000-03-09 2001-09-13 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
CA2826724C (en) 2000-04-11 2016-02-02 Trudell Medical International Aerosol delivery apparatus with positive expiratory pressure capacity
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
EP1280520B2 (de) 2000-05-10 2018-03-21 Novartis AG Pulver auf basis von phospholipiden zur wirkstoffverabreichung
US6668827B2 (en) 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
US6849259B2 (en) 2000-06-16 2005-02-01 Symphogen A/S Polyclonal antibody composition for treating allergy
US6457471B1 (en) * 2000-06-30 2002-10-01 Medihale Ltd. Dual-purpose medical device for upper airway treatment and methods for using same
GB0023654D0 (en) * 2000-09-27 2000-11-08 Cambridge Consultants Device for administering doses of particulate material
GB0025749D0 (en) * 2000-10-20 2000-12-06 Glaxo Group Ltd Inhaler
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6701921B2 (en) 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US6799572B2 (en) 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US6945688B2 (en) * 2001-01-10 2005-09-20 Stryker Instruments Container assembly for mixing materials
US20020110046A1 (en) * 2001-01-19 2002-08-15 Robertson James F. Fluid agitator and conditioner
CA2441100C (en) * 2001-03-20 2013-05-21 Trudell Medical International Nebulizer apparatus with an adjustable fluid orifice
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
US6766799B2 (en) 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
CA2445516C (en) * 2001-04-26 2007-11-20 New England Pharmaceuticals, Inc. Metered dose delivery device for liquid and powder agents
US7905230B2 (en) 2001-05-09 2011-03-15 Novartis Ag Metered dose inhaler with lockout
WO2002089880A2 (en) * 2001-05-10 2002-11-14 Vectura Delivery Devices Limited Inhalers
EG24184A (en) 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
NZ519403A (en) * 2001-06-21 2005-03-24 Pfizer Prod Inc Use of insulin in a medicament to reduce weight gain in a diabetic patient who is using exogenous insulin to control blood sugar levels
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
WO2003026559A2 (en) 2001-09-28 2003-04-03 Kurve Technology, Inc Nasal nebulizer
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6804458B2 (en) 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
US6994083B2 (en) * 2001-12-21 2006-02-07 Trudell Medical International Nebulizer apparatus and method
JP2003199827A (ja) * 2001-12-28 2003-07-15 Terumo Corp シリンジ
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
PT1485154E (pt) * 2002-03-20 2008-06-17 Alkermes Inc Dispositivo de inalação de pó
US20030205226A1 (en) 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
AU2003249623A1 (en) * 2002-05-09 2003-12-12 Kurve Technology, Inc. Particle dispersion chamber for nasal nebulizer
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
US6799571B1 (en) * 2002-06-19 2004-10-05 Molecular Rotation, Llc Medicinal powder delivery system
DE10244795A1 (de) * 2002-09-26 2004-04-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
WO2004054606A1 (en) * 2002-12-13 2004-07-01 Pfizer Products Inc. Method of decreasing hepatic glucose output in diabetic patients
CA2508268A1 (en) * 2002-12-19 2004-07-08 Koninklijke Philips Electronics N.V. Discrete-amount fluid-dispensing system for a personal care device
US20040187866A1 (en) * 2003-03-31 2004-09-30 Nathaniel Hughes Liquid medicament delivery system
JP4943838B2 (ja) 2003-04-09 2012-05-30 ネクター セラピューティクス 空気入口シールドを備えたエアゾール化装置
US7726308B1 (en) 2003-05-09 2010-06-01 Maurino Flora Apparatus and method for respiratory drug delivery
US6971385B1 (en) 2003-05-09 2005-12-06 Maurino Flora Apparatus and method for respiratory drug delivery
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
US7270123B2 (en) * 2003-08-13 2007-09-18 Trudell Medical International Nebulizer apparatus and method
GB2405798A (en) * 2003-09-15 2005-03-16 Vectura Ltd Dry powder inhaler with primary and secondary piercing elements and a medicament pack for use with an inhalation device.
US7159507B2 (en) 2003-12-23 2007-01-09 Philip Morris Usa Inc. Piston pump useful for aerosol generation
CA2553392A1 (en) * 2004-01-16 2005-08-11 Biodel Inc Sublingual drug delivery device
US20050183718A1 (en) * 2004-02-24 2005-08-25 Boehringer Ingelheim International Gmbh Nebulizer
DE102004012093A1 (de) * 2004-03-05 2005-09-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator mit Merkanaldüse
CN1946453A (zh) * 2004-04-23 2007-04-11 米斯提克医药有限公司 多倍剂量药品配给系统
US7861712B2 (en) 2004-04-23 2011-01-04 Manta Product Development Sealed capsule including an integrated puncturing mechanism
DK1765288T3 (da) 2004-06-18 2013-02-11 Novartis Ag Tobramycinpræparater til behandling af endobronchiale infektioner
CN105801686B (zh) 2004-07-19 2020-04-07 比奥孔有限公司 胰岛素-低聚物共轭物、制剂及其用途
AU2005266789B2 (en) 2004-07-26 2010-11-25 1355540 Ontario Inc. Powder inhaler featuring reduced compaction inhaler
CA2575706A1 (en) * 2004-08-02 2006-02-23 Bebaas, Inc. Vitamin b12 compositions
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
WO2006037636A2 (en) * 2004-10-06 2006-04-13 Boehringer Ingelheim International Gmbh Dispensing device, storage device and method for dispensing powder
GB0427858D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0427853D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
FR2881120B1 (fr) * 2005-01-25 2010-07-30 Valois Sas Dispositif de distribution de produit fluide.
FR2881117B1 (fr) * 2005-01-25 2010-07-30 Valois Sas Dispositif de distribution de produit fluide.
GB0507711D0 (en) * 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
JP2009507071A (ja) * 2005-09-07 2009-02-19 ビバース、インコーポレイテッド ビタミンｂ１２組成物
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
DE102005043449B3 (de) * 2005-09-13 2006-08-03 Braunform Gmbh Vorrichtung zum Inhalieren eines Pulvers
DK1937219T3 (en) 2005-09-14 2016-02-15 Mannkind Corp A method for drug formulation based on increasing the affinity of the crystalline surfaces of the microparticle of active principles
CA2623256A1 (en) * 2005-09-29 2007-04-12 Nektar Therapeutics Receptacles and kits, such as for dry powder packaging
AR058289A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
MX2008009325A (es) * 2006-02-20 2008-12-18 Boehringer Ingelheim Int Inhalador.
IN2015DN00888A (de) 2006-02-22 2015-07-10 Mannkind Corp
ES2265789B1 (es) * 2006-03-02 2008-02-01 Saint-Gobain Calmar, S.A. Bomba pulverizadora aplanada.
US20070299400A1 (en) * 2006-03-16 2007-12-27 Seattle Medical Technologies Infusion device with dome pump
DE102006014434A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Packmittel für Mehrdosispulverinhalatoren mit optimierten Entleerungseigenschaften
US8037880B2 (en) * 2006-04-07 2011-10-18 The University Of Western Ontario Dry powder inhaler
US9457161B2 (en) 2006-05-18 2016-10-04 Boehringer Ingelheim International Gmbh Inhaler
DE102006023662A1 (de) * 2006-05-18 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DK2056903T3 (en) * 2006-08-31 2019-01-28 Meridian Medical Tech Inc Swirl function for drug delivery system
EP2077882A2 (de) * 2006-10-25 2009-07-15 Nektar Therapeutics Pulverdispersionsvorrichtung, verfahren zur herstellung und verwendung dieser vorrichtung und komponenten zur verwendung mit dieser vorrichtung oder anderen geräten
CA2675030C (en) 2007-01-09 2015-06-09 Mystic Pharmaceuticals, Inc. Intranasal cartridge devices
WO2008091355A2 (en) * 2007-01-24 2008-07-31 Breathe Pharmaceuticals, Inc. Drug transfer device
EP1992374A1 (de) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
EP1992379A1 (de) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
EP1992380A1 (de) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
US8683995B2 (en) 2007-05-16 2014-04-01 Mystic Pharmaceuticals, Inc. Dose dispensing containers
EP1992376A1 (de) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
EP1992381A1 (de) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
EP2164799B1 (de) * 2007-05-16 2018-12-26 Mystic Pharmaceuticals, Inc. Kombinationsdosiereinheitabgabebehälter
EP1992372A1 (de) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
EP1992377A1 (de) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
EP1992373A1 (de) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
WO2008156586A2 (en) * 2007-06-12 2008-12-24 Alkermes, Inc. Inhalation device for powdered substances
EP3453418A1 (de) * 2007-07-06 2019-03-13 Manta Devices, LLC Ausgabevorrichtung und zugehörige verfahren
WO2009007068A1 (en) * 2007-07-06 2009-01-15 Boehringer Ingelheim International Gmbh Inhaler
US11224704B2 (en) 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
EP2020249A1 (de) * 2007-08-01 2009-02-04 Boehringer Ingelheim Pharma GmbH & Co. KG Inhalator
JP2010538925A (ja) * 2007-09-14 2010-12-16 ミスティック ファーマシューティカルズ， インコーポレイテッド 深絞り容器成形方法
US8291902B2 (en) * 2007-09-18 2012-10-23 Robert Abrams Enhanced semi-automatic emergency medication dose nebulizer
EP2207890A4 (de) 2007-10-05 2010-12-15 Barofold Inc Hochdruckbehandlung aggregierter interferone
US8931478B2 (en) 2007-11-19 2015-01-13 Carefusion 2200, Inc. Patient interface assembly for respiratory therapy
EP2077132A1 (de) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung
EP2082759A1 (de) 2008-01-24 2009-07-29 Boehringer Ingelheim International GmbH Inhalator
EP2082763A1 (de) 2008-01-24 2009-07-29 Boehringer Ingelheim International Gmbh Inhalator
EP2082762A1 (de) 2008-01-24 2009-07-29 Boehringer Ingelheim International Gmbh Inhalator
US20100201082A1 (en) * 2008-04-24 2010-08-12 Hart Jamie R Multilayer Seal for a Container
JP2011519679A (ja) * 2008-05-06 2011-07-14 ウィルソン−クック・メディカル・インコーポレーテッド 治療薬を送達するための器具及び方法
KR101933816B1 (ko) 2008-06-13 2019-03-29 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2135632A1 (de) * 2008-06-20 2009-12-23 Boehringer Ingelheim International Gmbh Inhalator
EP2609954B1 (de) 2008-06-20 2021-12-29 MannKind Corporation Interaktives Gerät für die Echtzeit-Profilierung von Inhalationsversuchen
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
CN102159270B (zh) 2008-09-26 2014-07-02 奥里尔治疗公司 一种带有具有气道盘沟槽的气道盘的吸入器和相关的气道盘和方法
EP2346554B1 (de) * 2008-09-26 2015-09-16 Oriel Therapeutics, Inc. Inhalationsmechanismus mit radial beanspruchten dornen und entsprechende verfahren
ES2528657T3 (es) * 2008-09-26 2015-02-11 Oriel Therapeutics, Inc. Inhaladores de polvo seco con elementos de perforación dual y dispositivos y métodos relacionados
US9050427B2 (en) * 2008-09-30 2015-06-09 Oriel Therapeutics, Inc. Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods
CA2732827C (en) * 2008-10-01 2016-10-11 Oriel Therapeutics, Inc. Dry powder inhalers with rotating piercing mechanisms and related devices and methods
GB0818476D0 (en) * 2008-10-09 2008-11-12 Vectura Delivery Device Ltd Inhaler
EP2198907A1 (de) 2008-12-19 2010-06-23 Boehringer Ingelheim International GmbH Inhalator
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8550074B2 (en) 2009-01-15 2013-10-08 Manta Devices, Llc Delivery device and related methods
EP2210638B1 (de) * 2009-01-26 2013-03-27 Boehringer Ingelheim International GmbH Inhalator
GB0901520D0 (en) * 2009-01-30 2009-03-11 Vectura Delivery Devices Ltd Inhaler
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010112358A2 (de) 2009-03-31 2010-10-07 Boehringer Ingelheim International Gmbh Verfahren zur beschichtung einer oberfläche eines bauteils
MX2011012133A (es) * 2009-05-15 2011-12-06 Glaxosmithkline Llc Uso de formacion de imagen termica para control de un proceso de fabricacion.
JP5763053B2 (ja) 2009-05-18 2015-08-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アダプタ、吸入器具及びアトマイザ
KR101567125B1 (ko) * 2009-05-27 2015-11-06 이노 테라퓨틱스 엘엘씨 인덱싱된 밸브와 압축 캐니스터 조립체를 칼라에 결합하고 플런저 조립체로 선형 작동시켜 약물 전달 조절용 장치와 유체 소통상태가 되게 하는 방법 및 장치
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
CN104799969B (zh) * 2009-06-25 2018-11-06 贝林格尔·英格海姆维特梅迪卡有限公司 吸入器
JP5656996B2 (ja) 2009-07-13 2015-01-21 ザ ユニバーシティ オブ ノース キャロライナ アット チャペル ヒル 工学的に作製されたエアロゾル粒子、およびそれに関連した方法
WO2011013003A2 (en) 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EA026241B1 (ru) 2009-11-25 2017-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Распылитель
WO2011079310A1 (en) * 2009-12-23 2011-06-30 Map Pharmaceuticals,Inc. Enhanced eductor design
WO2011116293A2 (en) 2010-03-19 2011-09-22 Manta Devices, Llc Delivery device and related methods
USD641076S1 (en) 2010-03-26 2011-07-05 Oriel Therapeutics, Inc. Dry powder inhaler
USD635246S1 (en) 2010-03-26 2011-03-29 Oriel Therapeutics, Inc. Dose disk for dry powder inhalers
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
JP5874724B2 (ja) 2010-06-24 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
ES2659761T3 (es) 2011-01-31 2018-03-19 Shin Nippon Biomedical Laboratories, Ltd. Dispositivos de administración intranasal
JOP20120023B1 (ar) 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US11103659B2 (en) 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
JP5885953B2 (ja) * 2011-07-25 2016-03-16 株式会社カワタ 粉体分散装置および方法
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
US9744318B2 (en) * 2011-12-16 2017-08-29 Novartis Ag Aerosolization apparatus for inhalation profile-independent drug delivery
US20150010527A1 (en) 2012-02-01 2015-01-08 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy
PL2817052T3 (pl) 2012-02-24 2018-01-31 Optinose As Urządzenia do podawania donosowego
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
US9649454B2 (en) 2012-05-03 2017-05-16 Manta Devices, Llc Delivery device and related methods
DK178263B1 (en) 2012-06-12 2015-10-19 Ictalcare As Method and system of detecting seizures
WO2014004400A2 (en) * 2012-06-28 2014-01-03 The Governt. Of The Usa As Represented By The Secretary Of The Department Of Health & Human Services Nasal dry powder delivery system for vaccines and other treatment agents
AU2013285433A1 (en) * 2012-07-05 2015-01-22 Glaxo Group Limited Inhaler device
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
UA111442C2 (uk) * 2012-10-02 2016-04-25 Кмс Ді Колозіо Мауро Інгаляційний пристрій
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
GB201301192D0 (en) 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
MX2015012529A (es) 2013-03-14 2016-07-05 Novartis Ag Deamorfizacion de formulaciones secadas por pulverizacion a traves de pulverizacion de la mezcla.
US9452139B2 (en) 2013-03-14 2016-09-27 Novartis Ag Respirable agglomerates of porous carrier particles and micronized drug
EP2970149B1 (de) 2013-03-15 2019-08-21 MannKind Corporation Mikrokristalline diketopiperazinzusammensetzungen und verfahren
GB2514893B (en) * 2013-06-04 2017-12-06 Nicoventures Holdings Ltd Container
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
EP2835146B1 (de) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Zerstäuber
US9744313B2 (en) 2013-08-09 2017-08-29 Boehringer Ingelheim International Gmbh Nebulizer
SI3035885T1 (sl) * 2013-08-20 2020-04-30 Boehringer Ingelheim Vetmedica Gmbh Inhalator
MX2016002020A (es) 2013-08-20 2016-05-18 Boehringer Ingelheim Vetmed Inhalador.
RS61221B1 (sr) 2013-08-20 2021-01-29 Boehringer Ingelheim Vetmedica Gmbh Inhalator
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
WO2015168572A2 (en) 2014-05-02 2015-11-05 Manta Devices, Llc Delivery device and related methods
EP3139984B1 (de) 2014-05-07 2021-04-28 Boehringer Ingelheim International GmbH Zerstäuber
NZ724449A (en) 2014-05-07 2022-01-28 Boehringer Ingelheim Int Nebulizer and container
DK3139979T3 (da) 2014-05-07 2023-10-09 Boehringer Ingelheim Int Enhed, forstøver og fremgangsmåde
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US20170304459A1 (en) 2014-10-10 2017-10-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
CN107106641B (zh) 2014-10-31 2021-12-21 葛兰素史密斯克莱知识产权发展有限公司 粉末制剂
DE102014116694A1 (de) 2014-11-14 2016-05-19 Bluestone Technology GmbH Verfahren und Vorrichtung zur kontrollierten Abgabe von Partikeln
RU2697372C2 (ru) * 2014-12-19 2019-08-13 Ино Терапьютикс Ллс Устройства и способы обеспечения взаимодействия указательного узла, содержащего клапан и находящийся под давлением баллон, с хомутом и линейного перемещения толкательным узлом для создания гидродинамической связи с устройством для регулируемой подачи медикамента
WO2016127004A1 (en) 2015-02-04 2016-08-11 Lubby Holdings, LLC Personal vaporizer with medium and chamber control
EP3058973A1 (de) * 2015-02-19 2016-08-24 Sanofi-Aventis Deutschland GmbH Zusätzvorrichtung zur lösbaren befestigung an einer arzneimitteleinspritzvorrichtung
WO2017053994A1 (en) * 2015-09-25 2017-03-30 Lubby Holdings Llc Personal vaporizer having reversing air flow
JP6899631B2 (ja) * 2016-03-09 2021-07-07 株式会社神鋼環境ソリューション 分散ノズル
WO2017199215A1 (en) 2016-05-19 2017-11-23 Trudell Medical International Smart valved holding chamber
US10786638B2 (en) 2016-07-08 2020-09-29 Trudell Medical International Nebulizer apparatus and method
US10881818B2 (en) 2016-07-08 2021-01-05 Trudell Medical International Smart oscillating positive expiratory pressure device
CN107782575B (zh) * 2016-08-26 2020-08-28 杭州奥泰生物技术股份有限公司 一种收集和检测样本中被分析物质的系统及其方法
GR1009186B (el) * 2016-09-28 2018-01-09 Κωνσταντινος Παυλου Ζαρογουλιδης Συσκευη χορηγησης εισπνεομενων φαρμακων σε μορφη ξηρας σκονης με αποσπωμενες κεφαλες για τη ρυθμιση της αντιστασης
CA3036631A1 (en) 2016-12-09 2018-06-14 Trudell Medical International Smart nebulizer
GB201702406D0 (en) * 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods
US11690964B2 (en) 2017-05-31 2023-07-04 Virginia Commonwealth University Devices, systems, and methods for dry powder therapies
GB201713899D0 (en) * 2017-08-30 2017-10-11 Indosys Ltd Multi-dose medicament delivery device
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
WO2019104192A1 (en) * 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Intranasal device with inlet interface
EP3735287A4 (de) 2018-01-04 2021-09-15 Trudell Medical International Intelligente schwingende vorrichtung für positiven ausatmungsdruck
US11825883B2 (en) 2018-07-16 2023-11-28 Lubby Holdings, LLC Personal vaporizer
CN109674495B (zh) * 2018-08-01 2021-02-26 浙江三创生物科技有限公司 给药方法及其装置
US11730201B2 (en) 2019-04-15 2023-08-22 Vaporous Technologies, Inc. Personal vaporizer having a heating element with multiple surfaces
AU2020338979A1 (en) 2019-08-27 2022-03-17 Trudell Medical International Inc. Smart oscillating positive expiratory pressure device
RU200686U1 (ru) * 2020-01-22 2020-11-05 Федеральное государственное бюджетное учреждение "48 Центральный научно-исследовательский институт" Министерства обороны Российской Федерации Распыливающее устройство
CN111317173A (zh) * 2020-03-26 2020-06-23 深圳市长能汇科科技有限公司 一种具有防漏液结构和气道对冲结构的烟具
RU2745231C9 (ru) * 2020-06-08 2021-04-27 Акционерное общество "Столетика" Спрей-ингалятор с функцией приготовления и хранения лекарственных форм
KR20230031322A (ko) 2020-06-27 2023-03-07 크레센타 바이오사이언시즈 세포 물질대사를 조정하는 화합물의 조성물 및 사용 방법
CN114392454B (zh) * 2022-02-09 2024-07-02 商丘市中心医院 一种临床麻醉用局部麻醉可控喷雾装置
WO2023209665A1 (en) * 2022-04-29 2023-11-02 Merxin Ltd A medicament dispenser for dispersing dry powder medicaments
EP4360475A1 (de) * 2022-10-25 2024-05-01 JT International SA Vorrichtung zum inhalieren von trockenen partikeln einer substanz auf nikotinbasis
GB202218332D0 (en) * 2022-12-06 2023-01-18 Cambridge Healthcare Innovations Ltd Drug-delivery device and method

Family Cites Families (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US478744A (en) 1892-07-12 William james evans
US2603216A (en) * 1952-07-15 Powder inhaler
DE471490C (de) 1931-08-12 Karl Zeyen Vorrichtung zum Zerstaeuben mehlfoermiger Stoffe
US513189A (en) 1894-01-23 Powder-blower
US2533065A (en) 1947-03-08 1950-12-05 George V Taplin Micropulverized therapeutic agents
US2570774A (en) 1947-10-21 1951-10-09 Frank P C Davis Insufflator
GB636854A (en) 1948-05-20 1950-05-10 Thomas James Chalmers Macdonal Apparatus for administering anaesthetics
US2549303A (en) * 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
US2598525A (en) * 1950-04-08 1952-05-27 E & J Mfg Co Automatic positive pressure breathing machine
DE1147354B (de) 1961-08-07 1963-04-18 Paul Ritzau Vernebler, insbesondere Handvernebler fuer Inhalationszwecke
US3362405A (en) 1964-04-06 1968-01-09 Hamilton O. Hazel Method and apparatus for admixing gas with solid particles
US3425600A (en) * 1966-08-11 1969-02-04 Abplanalp Robert H Pressurized powder dispensing device
US3583491A (en) * 1969-01-30 1971-06-08 Serlachius Oy Portable fire extinguisher construction
US3812854A (en) 1972-10-20 1974-05-28 A Michaels Ultrasonic nebulizer
US4069819A (en) * 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
GB1479283A (en) 1973-07-23 1977-07-13 Bespak Industries Ltd Inhaler for powdered medicament
DE2346914C3 (de) * 1973-09-18 1980-10-16 Paul Ritzau Pari-Werk, Gmbh & Co, 8130 Starnberg Inhalator für pulverförmige Substanzen
FR2257351A1 (en) 1974-01-11 1975-08-08 Obert Jean Claude Aerosol device for solid vaccines - feed and breaker screws deliver material sideways into blower chamber
IT1016489B (it) * 1974-03-18 1977-05-30 Isf Spa Inalatore
US3967761A (en) * 1974-04-08 1976-07-06 Southwest Research Institute System for injecting particulate material into the combustion chamber of a repetitive combustion coating apparatus
YU41046B (en) 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
SU628930A1 (ru) * 1974-11-26 1978-10-25 Московский научно-исследовательский институт туберкулеза Устройство дл введени порошкообразного лекарственного вещества
US4005711A (en) 1975-01-13 1977-02-01 Syntex Puerto Rico, Inc. Inhalation device
US3964483A (en) 1975-01-13 1976-06-22 Syntex Puerto Rico, Inc. Inhalation device
FR2299011A1 (fr) 1975-01-29 1976-08-27 Obert Jean Claude Generateur d'aerosols de part
US3991304A (en) 1975-05-19 1976-11-09 Hillsman Dean Respiratory biofeedback and performance evaluation system
GB1521000A (en) * 1975-06-13 1978-08-09 Syntex Puerto Rico Inc Inhalation device
US3994421A (en) * 1975-09-29 1976-11-30 American Cyanamid Company Unitary therapeutic aerosol dispenser
SE408265B (sv) * 1975-12-12 1979-06-05 Draco Ab Anordning for koldioxiddriven endosaerosol, avsedd for inhalering
US4018185A (en) * 1975-12-15 1977-04-19 Coors Container Company Powder feeder pick-up tube
NL7712041A (en) * 1977-11-01 1979-05-03 Handelmaatschappij Voorheen Be Suction equipment for powdery material - incorporates ejector type suction pump and cyclone type separator
DE2960616D1 (en) * 1978-05-03 1981-11-12 Fisons Plc Inhalation device
US4253468A (en) 1978-08-14 1981-03-03 Steven Lehmbeck Nebulizer attachment
SU1003926A1 (ru) * 1979-01-24 1983-03-15 Всесоюзный Научно-Исследовательский И Конструкторский Институт Автогенного Машиностроения Порошковый питатель
US4256241A (en) * 1979-02-01 1981-03-17 Mesic Robert S Pesticide duster
IT1116047B (it) * 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
EP0028162B1 (de) * 1979-10-30 1985-01-23 Riker Laboratories, Inc. Atmungsbetätigte Vorrichtungen zum Verabreichen pulverförmiger Medikamente
GB2063075B (en) 1979-11-07 1983-11-09 Sterwin Ag Dose indicator for inhalers
DE3006606A1 (de) * 1980-02-22 1981-08-27 Arthur 7250 Leonberg Raisch Vorrichtung zum entnehmen von blaettern aus ordnern
ZA811942B (en) 1980-03-25 1983-02-23 H Malem Nebulising apparatus
DE3023648A1 (de) 1980-06-24 1982-01-21 Jaeger, Erich, 8700 Würzburg Einrichtung zur untersuchung der atemwege auf reizstoff-ueberempfindlichkeit
ES506585A0 (es) * 1980-10-30 1982-09-01 Riker Laboratories Inc Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo
US4484577A (en) 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
US4823784A (en) 1982-04-30 1989-04-25 Cadema Medical Products, Inc. Aerosol inhalation apparatus
NO160330C (no) * 1982-10-08 1989-04-12 Glaxo Group Ltd Anordning for aa administrere medikamenter til pasienter og medikamentpakning for anordningen.
US4778054A (en) * 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
GB8314308D0 (en) * 1983-05-24 1983-06-29 Matburn Holdings Ltd Medical administration devices
US4570630A (en) * 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
US4649911A (en) 1983-09-08 1987-03-17 Baylor College Of Medicine Small particle aerosol generator for treatment of respiratory disease including the lungs
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
US4534343A (en) 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
US4624251A (en) 1984-09-13 1986-11-25 Riker Laboratories, Inc. Apparatus for administering a nebulized substance
FI76929C (fi) 1984-09-25 1989-01-10 Etelae Haemeen Keuhkovammayhdi Inhalationsdoseringsanordning, som aer avsedd foer nogrann dosering av disponerande laekemedel som ges aot andningssjuka i undersoekningsskedet och/eller laekemedel som ges som spray under behandlingen.
NZ209900A (en) 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
FR2575678B1 (fr) * 1985-01-04 1988-06-03 Saint Gobain Vitrage Ejecteur pneumatique de poudre
US4942544A (en) 1985-02-19 1990-07-17 Kenneth B. McIntosh Medication clock
SE448277B (sv) * 1985-04-12 1987-02-09 Draco Ab Indikeringsanordning vid en doseringsanordning for lekemedel
FI81500C (fi) 1985-05-23 1990-11-12 Etelae Haemeen Keuhkovammayhdi Andningsbehandlingsapparat.
NO166268C (no) * 1985-07-30 1991-07-03 Glaxo Group Ltd Innretning for administrering av medikamenter til pasienter.
SE453566B (sv) 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
US4739754A (en) 1986-05-06 1988-04-26 Shaner William T Suction resistant inhalator
US4926852B1 (en) 1986-06-23 1995-05-23 Univ Johns Hopkins Medication delivery system phase one
US4790305A (en) 1986-06-23 1988-12-13 The Johns Hopkins University Medication delivery system
DE3636669C2 (de) 1986-10-28 2001-08-16 Siemens Ag Anordnung zur Zufuhr von Aerosol zu den Luftwegen und/oder Lungen eines Patienten
IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli
GB8804069D0 (en) * 1988-02-22 1988-03-23 Britains Petite Ltd Dispensers for powdered medication
IT1217890B (it) 1988-06-22 1990-03-30 Chiesi Farma Spa Dispositivo per l'inalazione di aerosol dosati
US4852561A (en) 1988-07-27 1989-08-01 Sperry C R Inhalation device
ES2051371T3 (es) 1988-10-04 1994-06-16 Univ Johns Hopkins Inhalador de aerosoles.
US4984158A (en) * 1988-10-14 1991-01-08 Hillsman Dean Metered dose inhaler biofeedback training and evaluation system
DK479189D0 (da) * 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator
IT1228459B (it) * 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
SE466684B (sv) 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
DE3927170A1 (de) 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
IT1237118B (it) 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
US5113855A (en) 1990-02-14 1992-05-19 Newhouse Michael T Powder inhaler
DE4004904A1 (de) * 1990-02-16 1990-09-13 Gerhard Brendel Trommel-applikator
US5020527A (en) 1990-02-20 1991-06-04 Texax-Glynn Corporation Inhaler device with counter/timer means
IT1243344B (it) 1990-07-16 1994-06-10 Promo Pack Sa Inalatore plurimonodose per medicamenti in polvere
US5037912A (en) * 1990-07-26 1991-08-06 The Goodyear Tire & Rubber Company Polymerization of 1,3-butadiene to trans-1,4-polybutadiene with organolithium and alkali metal alkoxide
DE4027749A1 (de) * 1990-09-01 1992-03-05 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer medien
RU2095092C1 (ru) 1990-09-12 1997-11-10 Бисгорд Ханс Ингаляторное устройство для вдыхания активного порошкообразного или жидкого вещества
US5217004A (en) * 1990-12-13 1993-06-08 Tenax Corporation Inhalation actuated dispensing apparatus
US5099833A (en) 1991-02-19 1992-03-31 Baxter International Inc. High efficiency nebulizer having a flexible reservoir
US5404871A (en) 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5186164A (en) 1991-03-15 1993-02-16 Puthalath Raghuprasad Mist inhaler
DE59107894D1 (de) 1991-03-21 1996-07-11 Ritzau Pari Werk Gmbh Paul Vernebler insbesondere zur Anwendung in Geräten für die Inhalationstherapie
GB9106648D0 (en) 1991-03-28 1991-05-15 Rhone Poulenc Rorer Ltd New inhaler
DK0533683T3 (da) 1991-04-15 1997-01-13 Leiras Oy Indretning til måling af en dosis pulveriseret medikament til inhalering
CA2107792C (en) * 1991-05-21 1997-03-25 Akwete L. Adjei Aerosol inhalation device
RU2002467C1 (ru) * 1991-06-25 1993-11-15 Чучалин Александр Григорьевич; Бабарсков Евгений Викторович; Опенев В чеслав Иванович; Зезин Сергей Борисович; Коркина Людмила Георгиевна; Казначеев Владимир Александрович; Лох- мачев Александр Викторович Ингал тор дл введени лекарственных средств в виде порошка
DE69233690T2 (de) 1991-07-02 2008-01-24 Nektar Therapeutics, San Carlos Abgabevorrichtung für nebelförmige Medikamente
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5161524A (en) 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5287850A (en) * 1991-08-20 1994-02-22 Habley Medical Technology Corporation Timing and velocity controlled powered pharmaceutical inhaler
US6029661A (en) 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
DE4128295A1 (de) * 1991-08-27 1993-03-04 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer fliessfaehige medien
GB9123953D0 (en) 1991-11-12 1992-01-02 Minnesota Mining & Mfg Inhalation device
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5363842A (en) 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
DE4142238A1 (de) 1991-12-20 1993-06-24 Boehringer Ingelheim Kg Pulverinhalator mit pulvertraeger aus regelmaessigen mikrostrukturen
US5186166A (en) * 1992-03-04 1993-02-16 Riggs John H Powder nebulizer apparatus and method of nebulization
US5355872B1 (en) * 1992-03-04 1998-10-20 John H Riggs Low flow rate nebulizer apparatus and method of nebulization
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5284133A (en) 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
AU4829593A (en) * 1992-09-23 1994-04-12 Fisons Plc Inhalation device
PL172758B1 (pl) * 1992-10-19 1997-11-28 Dura Pharma Inc Inhalator do proszków suchych PL PL PL PL PL PL PL
US5290278A (en) 1992-10-20 1994-03-01 Proclosure Inc. Method and apparatus for applying thermal energy to luminal tissue
FR2700279B1 (fr) * 1993-01-14 1995-03-17 Valois Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé.
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
US5524613A (en) * 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5505194A (en) * 1994-03-23 1996-04-09 Abbott Laboratories Aerosol inhalation device having slideably and rotatably connected elliptical cylinder portions
JP3706136B2 (ja) 1994-09-21 2005-10-12 ネクター セラピューティクス 乾燥粉末薬剤の分散装置及び方法
GB9513218D0 (en) * 1995-06-29 1995-09-06 Fisons Plc Inhalation device and method
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5694920A (en) 1996-01-25 1997-12-09 Abrams; Andrew L. Inhalation device
JPH09253208A (ja) * 1996-03-21 1997-09-30 Unisia Jecs Corp 鼻腔用投薬器
HUP9901575A3 (en) 1996-04-29 1999-11-29 Dura Pharmaceuticals Inc San D Methods of dry powder inhalation
US6123070A (en) 1996-06-07 2000-09-26 Valois S.A. Device for enhancing the emptying of an inhaler metering chamber
DE19704849B4 (de) * 1997-02-08 2011-02-17 Ing. Erich Pfeiffer Gmbh Austragvorrichtung für Medien
DE19817417A1 (de) * 1998-04-18 1999-10-21 Pfeiffer Erich Gmbh & Co Kg Spender für Medien, insbesondere Pulver
US6257233B1 (en) * 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
US6591832B1 (en) * 2002-02-21 2003-07-15 Saint-Gobain Calmar Inc. Dry powder dispenser

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IL126325A0 (en) 1999-05-09
EP0846009A1 (de) 1998-06-10
JP3706136B2 (ja) 2005-10-12
NZ293163A (en) 1998-09-24
EP0846009B1 (de) 2008-03-05
HU220472B1 (hu) 2002-02-28
US6543448B1 (en) 2003-04-08
IL115369A (en) 2000-06-29
JPH10508790A (ja) 1998-09-02
NO20063519L (no) 1997-05-20
CA2555600A1 (en) 1996-03-28
AU3553295A (en) 1996-04-09
CA2606600A1 (en) 1996-03-28
CN1494951A (zh) 2004-05-12
BR9508964A (pt) 1998-06-02
US20030183229A1 (en) 2003-10-02
NO971316L (no) 1997-05-20
PL187750B1 (pl) 2004-09-30
US6089228A (en) 2000-07-18
CA2200727A1 (en) 1996-03-28
RU2146153C1 (ru) 2000-03-10
WO1996009085A1 (en) 1996-03-28
CZ289029B6 (cs) 2001-10-17
NZ331353A (en) 1999-07-29
CN1160358A (zh) 1997-09-24
PL319505A1 (en) 1997-08-18
AU697676B2 (en) 1998-10-15
IL115369A0 (en) 1995-12-31
FI971173A (fi) 1997-03-20
CN1318104C (zh) 2007-05-30
EP0846009A4 (de) 1999-07-28
PL188625B1 (pl) 2005-03-31
CA2606600C (en) 2009-09-01
ES2302332T3 (es) 2008-07-01
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CA2200727C (en) 2006-11-28
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CA2555600C (en) 2008-01-29
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