IT1237118B - Inalatore multidose per farmaci in polvere. - Google Patents

Inalatore multidose per farmaci in polvere.

Info

Publication number
IT1237118B
IT1237118B IT02217289A IT2217289A IT1237118B IT 1237118 B IT1237118 B IT 1237118B IT 02217289 A IT02217289 A IT 02217289A IT 2217289 A IT2217289 A IT 2217289A IT 1237118 B IT1237118 B IT 1237118B
Authority
IT
Italy
Prior art keywords
unit
dose
medicament
cup
powder form
Prior art date
Application number
IT02217289A
Other languages
English (en)
Other versions
IT8922172A0 (it
IT8922172A1 (it
Inventor
Salvatore Cocozza
Original Assignee
Miat Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miat Spa filed Critical Miat Spa
Publication of IT8922172A0 publication Critical patent/IT8922172A0/it
Priority to IT02217289A priority Critical patent/IT1237118B/it
Priority to DE90119877T priority patent/DE69002581T2/de
Priority to EP90119877A priority patent/EP0424790B1/en
Priority to AT90119877T priority patent/ATE92349T1/de
Priority to DK90119877.0T priority patent/DK0424790T3/da
Priority to ES90119877T priority patent/ES2044365T3/es
Priority to FI905163A priority patent/FI100306B/fi
Priority to IL9606190A priority patent/IL96061A/en
Priority to CA002028192A priority patent/CA2028192C/en
Priority to US07/601,417 priority patent/US5033463A/en
Priority to NZ235809A priority patent/NZ235809A/xx
Priority to AU64987/90A priority patent/AU625927B2/en
Priority to ZA908563A priority patent/ZA908563B/xx
Priority to TR90/1024A priority patent/TR24793A/xx
Priority to JP2287381A priority patent/JP2515175B2/ja
Priority to NO904661A priority patent/NO176468C/no
Priority to SI9012031A priority patent/SI9012031A/sl
Priority to YU203190A priority patent/YU47804B/sh
Priority to SU4831612A priority patent/RU1837897C/ru
Priority to KR1019900017279A priority patent/KR970009719B1/ko
Publication of IT8922172A1 publication Critical patent/IT8922172A1/it
Application granted granted Critical
Publication of IT1237118B publication Critical patent/IT1237118B/it
Priority to HRP-2031/90A priority patent/HRP931068B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nozzles (AREA)
  • Food-Manufacturing Devices (AREA)
  • Window Of Vehicle (AREA)
  • Quick-Acting Or Multi-Walled Pipe Joints (AREA)
IT02217289A 1989-10-27 1989-10-27 Inalatore multidose per farmaci in polvere. IT1237118B (it)

Priority Applications (21)

Application Number Priority Date Filing Date Title
IT02217289A IT1237118B (it) 1989-10-27 1989-10-27 Inalatore multidose per farmaci in polvere.
DE90119877T DE69002581T2 (de) 1989-10-27 1990-10-17 Multi-Dosierungsinhalierer für Medikamente in Pulverform.
EP90119877A EP0424790B1 (en) 1989-10-27 1990-10-17 Multi-dose inhaler for medicaments in powder form
AT90119877T ATE92349T1 (de) 1989-10-27 1990-10-17 Multi-dosierungsinhalierer fuer medikamente in pulverform.
DK90119877.0T DK0424790T3 (da) 1989-10-27 1990-10-17 Multi-dosis-inhalationsapparat for pulverformige lægemidler
ES90119877T ES2044365T3 (es) 1989-10-27 1990-10-17 Inhalador multidosis para medicamentos en polvo.
FI905163A FI100306B (fi) 1989-10-27 1990-10-19 Jauhemuodossa olevien lääkkeiden moniannos-lääkkeenhengityskoje
IL9606190A IL96061A (en) 1989-10-27 1990-10-19 A multi-dose inhaler of powdered drugs
CA002028192A CA2028192C (en) 1989-10-27 1990-10-22 Multi-dose inhaler for medicaments in powder form
US07/601,417 US5033463A (en) 1989-10-27 1990-10-22 Multi-dose inhaler for medicaments in powder form
NZ235809A NZ235809A (en) 1989-10-27 1990-10-24 Inhaler for powdered medicament: cup conveys powder
AU64987/90A AU625927B2 (en) 1989-10-27 1990-10-24 Multi-dose inhaler for medicaments in powder form
ZA908563A ZA908563B (en) 1989-10-27 1990-10-25 Multi-dose inhaler for medicaments in powder form
YU203190A YU47804B (sr) 1989-10-27 1990-10-26 Višedozni inhalator za lekove u vidu praška
JP2287381A JP2515175B2 (ja) 1989-10-27 1990-10-26 粉末状薬剤用マルチド―ス吸入器
NO904661A NO176468C (no) 1989-10-27 1990-10-26 Flerdoseinhalator for medikamenter i pulverform
SI9012031A SI9012031A (en) 1989-10-27 1990-10-26 Multi-dose inhalator for medicaments in powder form
TR90/1024A TR24793A (tr) 1989-10-27 1990-10-26 Toz halindeki ilaclara mahsus degisik dozlu inhalatoer.
SU4831612A RU1837897C (ru) 1989-10-27 1990-10-26 Многоразовый ингал тор порошков
KR1019900017279A KR970009719B1 (ko) 1989-10-27 1990-10-27 분말형태의약의다중-복용량흡입장치
HRP-2031/90A HRP931068B1 (en) 1989-10-27 1993-07-19 Multi-dose inhaler for medicaments in a powdered form

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02217289A IT1237118B (it) 1989-10-27 1989-10-27 Inalatore multidose per farmaci in polvere.

Publications (3)

Publication Number Publication Date
IT8922172A0 IT8922172A0 (it) 1989-10-27
IT8922172A1 IT8922172A1 (it) 1991-04-27
IT1237118B true IT1237118B (it) 1993-05-18

Family

ID=11192571

Family Applications (1)

Application Number Title Priority Date Filing Date
IT02217289A IT1237118B (it) 1989-10-27 1989-10-27 Inalatore multidose per farmaci in polvere.

Country Status (21)

Country Link
US (1) US5033463A (it)
EP (1) EP0424790B1 (it)
JP (1) JP2515175B2 (it)
KR (1) KR970009719B1 (it)
AT (1) ATE92349T1 (it)
AU (1) AU625927B2 (it)
CA (1) CA2028192C (it)
DE (1) DE69002581T2 (it)
DK (1) DK0424790T3 (it)
ES (1) ES2044365T3 (it)
FI (1) FI100306B (it)
HR (1) HRP931068B1 (it)
IL (1) IL96061A (it)
IT (1) IT1237118B (it)
NO (1) NO176468C (it)
NZ (1) NZ235809A (it)
RU (1) RU1837897C (it)
SI (1) SI9012031A (it)
TR (1) TR24793A (it)
YU (1) YU47804B (it)
ZA (1) ZA908563B (it)

Families Citing this family (227)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK544589D0 (da) * 1989-11-01 1989-11-01 Novo Nordisk As Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof
DE4004904A1 (de) * 1990-02-16 1990-09-13 Gerhard Brendel Trommel-applikator
MY105368A (en) * 1990-03-02 1994-09-30 Glaxo Group Ltd Inhalation device.
HU213221B (en) 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
GB9021433D0 (en) * 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
AU650953B2 (en) * 1991-03-21 1994-07-07 Novartis Ag Inhaler
AU650873B2 (en) * 1991-04-15 1994-07-07 Leiras Oy Device intended for measuring a dose of powdered medicament for inhalation
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
IT1248059B (it) * 1991-06-14 1995-01-05 Miat Spa Insufflatore multidose per farmaci in polvere
AU661857B2 (en) * 1991-06-26 1995-08-10 Merck Sharp & Dohme Corp. Inhalation device for powdered medicaments
ES2284226T3 (es) * 1991-07-02 2007-11-01 Nektar Therapeutics Dispositivo para proporcionar medicamentos en aerosol.
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
AU651910B2 (en) * 1991-08-15 1994-08-04 Franco Del Bon Inhaler
US6029661A (en) * 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
WO1993003785A2 (en) * 1991-08-26 1993-03-04 Minnesota Mining And Manufacturing Company Powder dispenser
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
GB9203761D0 (en) * 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
SE9201411D0 (sv) * 1992-05-05 1992-05-05 Astra Ab Dosage inhalator with indicating/interupting means
US5249424A (en) * 1992-06-05 1993-10-05 Astronautics Corporation Of America Active magnetic regenerator method and apparatus
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
IL106930A0 (en) * 1992-09-08 1993-12-28 Norton Healthcare Ltd Medicament dispensing device
EP0679088B1 (en) 1992-09-29 2002-07-10 Inhale Therapeutic Systems Pulmonary delivery of active fragments of parathyroid hormone
SK51695A3 (en) * 1992-10-19 1995-11-08 Dura Pharma Inc Dry powder medicament inhaler
AU683036B2 (en) * 1992-12-18 1997-10-30 Merck Sharp & Dohme Corp. Inhaler for powdered medications
US5896855A (en) * 1992-12-24 1999-04-27 Rhone-Poulenc Rorer Limited Multi dose inhaler apparatus
ES2115923T3 (es) * 1992-12-24 1998-07-01 Rhone Poulenc Rorer Ltd Inhaladores.
FR2700279B1 (fr) * 1993-01-14 1995-03-17 Valois Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé.
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US7448375B2 (en) 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
IL108780A (en) * 1993-02-27 1999-06-20 Fisons Plc Inhalation device
WO1994020164A1 (en) * 1993-03-03 1994-09-15 Glaxo Wellcome Inc. Dry powder inhalator medicament carrier
KR100244690B1 (ko) * 1993-05-12 2000-02-15 야스이 쇼사꾸 분말상 약제 멀티도스 시약장치
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
GB9326574D0 (en) * 1993-12-31 1994-03-02 King S College London Dry power inhalers
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
CZ295827B6 (cs) 1994-03-07 2005-11-16 Nektar Therapeutics Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití
US6290991B1 (en) * 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
HU220472B1 (hu) 1994-09-21 2002-02-28 Inhale Therapeutic Systems Eljárás és készülék por aeroszolosítására, valamint a készülékben alkalmazott adagolócső-egység
DE4440734A1 (de) * 1994-11-15 1996-05-23 Bayer Ag Abscheidesystem für einen Pulverinhalator
SE9404140D0 (sv) * 1994-11-29 1994-11-29 Astra Ab Dose indicating device
SE9404439D0 (sv) * 1994-12-21 1994-12-21 Astra Ab Inhalation device
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US5645051A (en) * 1995-04-21 1997-07-08 Dura Pharmaceuticals, Inc. Unit dose dry powder inhaler
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6357442B1 (en) 1995-06-08 2002-03-19 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIS)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US5826571A (en) * 1995-06-08 1998-10-27 Innovative Devices, Llc Device for use with metered dose inhalers (MDIS)
SE504458C2 (sv) * 1995-06-21 1997-02-17 Lars Gunnar Nilsson Inhalator för elektrisk dosering av substanser
US5988163A (en) * 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US5823183A (en) * 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US6209538B1 (en) * 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
FR2738153B1 (fr) * 1995-09-04 1998-01-02 Valois Appareil d'inhalation destine a distribuer des doses precises et reproductibles de produit pulverulent
DE19533979A1 (de) * 1995-09-14 1997-03-20 Alfred Von Schuckmann Gerät zur dosierten, luftgetragenen Ausgabe von Substanzen
DK0865302T3 (da) 1995-12-07 2000-10-02 Jago Pharma Ag Inhalator til gentagen dosisvis afgivelse af farmakologisk tørpulver
US7131441B1 (en) 1995-12-07 2006-11-07 Skyepharma Ag Inhaler for multiple dosed administration of a pharmacological dry powder
US5797392C1 (en) * 1996-01-22 2001-01-09 Direct Haler As Inhaler
DK0883415T3 (da) 1996-02-21 2002-08-19 Schering Corp Inhalator til pulverformigt medikament
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
GB2318737B (en) * 1996-10-30 2000-06-14 Bespak Plc Improved inhalers
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
SE9700937D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler I
SE9700936D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6237590B1 (en) * 1997-09-18 2001-05-29 Delsys Pharmaceutical Corporation Dry powder delivery system apparatus
US6293279B1 (en) 1997-09-26 2001-09-25 Trudell Medical International Aerosol medication delivery apparatus and system
US6345617B1 (en) * 1997-09-26 2002-02-12 1263152 Ontario Inc. Aerosol medication delivery apparatus and system
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
IT238038Y1 (it) 1997-11-12 2000-09-29 Miat Spa Erogatore multidose di una sostanza in polvere o in grani,del tipo incui l'approntamento di una dose comporta la rotazione di un alberino
US7967011B2 (en) * 1997-11-14 2011-06-28 Astrazeneca Ab Inhalation device
SE9704185D0 (sv) * 1997-11-14 1997-11-14 Astra Pharma Prod Inhalation device
US20060213505A1 (en) * 1997-11-14 2006-09-28 Astrazeneca Ab Inhalation device
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
HU224242B1 (hu) * 1998-01-30 2005-06-28 IG Sprühtechnik GmbH & Co. KG Inhaláló por alakú gyógyszerekhez
SE9801114D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
DE69928928T2 (de) * 1998-06-12 2006-08-03 Microdose Technologies Inc. Vorrichtung zur abgabe von arzneimitteln
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
FI990915A0 (fi) * 1999-04-23 1999-04-23 Orion Yhtymae Oyj Jauheinhalaattori
NZ515557A (en) 1999-06-05 2003-10-31 Innovata Biomed Ltd Delivery system
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
JP2003507410A (ja) * 1999-08-25 2003-02-25 アドバンスト インハレーション リサーチ，インコーポレイテッド 乾燥粉末製剤からの放出調節
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
AU2001241697A1 (en) * 2000-02-25 2001-10-30 Dura Pharmaceuticals, Inc. Dosing system for a dry powder inhaler
PT1142601E (pt) * 2000-04-07 2006-05-31 Andi Ventis Ltd Bocal para inalador de particulas
EP1272243B1 (en) 2000-04-11 2005-10-26 Trudell Medical International Aerosol delivery apparatus with positive expiratory pressure capacity
US6948494B1 (en) 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
TWI290473B (en) 2000-05-10 2007-12-01 Alliance Pharma Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
AU2001263098A1 (en) 2000-05-12 2001-11-26 Iep Pharmaceutical Devices, Inc. Powder/liquid metering valve
DK1163920T3 (da) * 2000-06-13 2005-02-28 Andi Ventis Ltd Mundstykke til en partikelinhalator
PE20020163A1 (es) * 2000-06-23 2002-03-04 Norton Healthcare Ltd Sistema presurizado de receptaculo para inhalador de medicamento
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
EP1326642A2 (en) * 2000-09-29 2003-07-16 Board of Trustees operating Michigan State University Catecholamine pharmaceutical compositions and methods
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
JP2005504715A (ja) * 2000-12-29 2005-02-17 アドバンスト インハレーション リサーチ，インコーポレイテッド 持続放出特性を有する吸入用粒子
US6626173B2 (en) 2001-01-08 2003-09-30 Iep Pharmaceutical Devices Inc. Dry powder inhaler
DE10129703A1 (de) 2001-06-22 2003-01-02 Sofotec Gmbh & Co Kg Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
WO2003020197A1 (en) * 2001-09-05 2003-03-13 Vectura Limited Improvements in or relating to the delivery of oral drugs
EP1450885B1 (en) 2001-09-28 2015-04-22 Kurve Technology, Inc. Nasal nebulizer
US6779520B2 (en) 2001-10-30 2004-08-24 Iep Pharmaceutical Devices Inc. Breath actuated dry powder inhaler
US7182961B2 (en) * 2001-11-20 2007-02-27 Advanced Inhalation Research, Inc. Particulate compositions for pulmonary delivery
WO2003043603A1 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Particulate compositions for improving solubility of poorly soluble agents
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
JP2005514393A (ja) 2001-12-19 2005-05-19 ネクター セラピューティクス アミノグリコシドの肺への供給
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US20030205226A1 (en) * 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US8122881B2 (en) 2002-05-09 2012-02-28 Kurve Technology, Inc. Particle dispersion device for nasal delivery
US6889690B2 (en) * 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
AU2003250210A1 (en) * 2002-08-06 2004-02-25 Glaxo Group Limited A dispenser
FR2849386B1 (fr) * 2002-12-27 2005-03-18 Bertin Technologies Sa Dispositif d'inhalation de poudre seche
JP4805814B2 (ja) * 2003-03-04 2011-11-02 ノートン・ヘルスケアー リミテッド 内部医薬リザーバの状態を表すディスプレイを有する医薬分与装置
EP1488819A1 (en) 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Dry powder inhaler and method for pulmonary inhalation of dry powder
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
ITMO20030229A1 (it) * 2003-08-07 2005-02-08 Roberto Oliva Inalatore per preparati in polvere.
FI20031158A7 (fi) * 2003-08-15 2005-02-16 Medifiq Healthcare Oy Inhalaattori
GB0323085D0 (en) 2003-10-02 2003-11-05 Norton Healthcare Ltd Dry powder inhalation apparatus
US7621273B2 (en) * 2003-10-28 2009-11-24 Trudell Medical International Indicating device with warning dosage indicator
EP1744800B1 (en) 2004-04-21 2016-06-22 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
MXPA06013846A (es) 2004-05-31 2007-03-01 Almirall Lab Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
ES2257152B1 (es) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
KR101488402B1 (ko) 2005-05-18 2015-02-03 엠펙스 파마슈티컬즈, 인코포레이티드 에어로졸화된 플루오로퀴놀론 및 이의 용도
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
ES2265276B1 (es) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
EP1965848A4 (en) * 2005-12-23 2012-12-05 Astrazeneca Ab NEW DEVICE
CA2644679C (en) * 2006-03-03 2013-12-03 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
MX2009000189A (es) * 2006-06-27 2009-01-22 Otsuka Pharma Co Ltd Inhalador de polvo.
WO2008051621A2 (en) * 2006-10-25 2008-05-02 Novartis Ag Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
AU2007338305B2 (en) * 2006-12-22 2013-05-09 Astrazeneca Ab Inhalation device for drugs in powder form
ES2306595B1 (es) 2007-02-09 2009-09-11 Laboratorios Almirall S.A. Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.
ES2320955B1 (es) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
WO2009029028A1 (en) * 2007-08-24 2009-03-05 Astrazeneca Ab Breath- triggered inhaler with dose counter
WO2009046215A2 (en) * 2007-10-02 2009-04-09 Lab International Srl Safety and abuse deterrent improved device
EP2058025B1 (en) * 2007-11-09 2014-09-03 Hitachi Ltd. Powder medicine administering apparatus
ES2320961B1 (es) 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2.
DK2230934T3 (da) 2007-12-14 2012-11-26 Aerodesigns Inc Afgivelse af aerosoliserbare næringsmiddelprodukter
EP2096105A1 (en) 2008-02-28 2009-09-02 Laboratorios Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2108641A1 (en) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
BRPI0920026B1 (pt) 2008-10-07 2023-11-07 Horizon Orphan Llc Composição farmacêutica e respectivos usos
ES2809177T3 (es) 2008-10-07 2021-03-03 Horizon Orphan Llc Inhalación de levofloxacino para reducir la inflamación pulmonar
EP2196465A1 (en) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
EP2221297A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases
EP2221055A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function
EP2226323A1 (en) 2009-02-27 2010-09-08 Almirall, S.A. New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives
EP2228368A1 (en) 2009-03-12 2010-09-15 Almirall, S.A. Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
EA021036B1 (ru) * 2009-04-23 2015-03-31 Такеда Гмбх Усовершенствованный аппарат для аэрозолизации больших объемов сухого порошка
FR2946537B1 (fr) * 2009-06-11 2012-08-03 Valois Sas Dispositif d'inhalation de poudre
SI2473170T1 (sl) 2009-09-04 2019-10-30 Horizon Orphan Llc Uporaba aerosoliziranega levofloksacina za zdravljenje cistične fibroze
EP2322176A1 (en) 2009-11-11 2011-05-18 Almirall, S.A. New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives
WO2011060334A2 (en) 2009-11-12 2011-05-19 Stc.Unm Dry powder inhaler with flutter dispersion member
EP2380890A1 (en) 2010-04-23 2011-10-26 Almirall, S.A. New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors
EP2386555A1 (en) 2010-05-13 2011-11-16 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities
EP2394998A1 (en) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
EP2441755A1 (en) 2010-09-30 2012-04-18 Almirall, S.A. Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
EP2463289A1 (en) 2010-11-26 2012-06-13 Almirall, S.A. Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors
ES2646748T3 (es) 2010-12-07 2017-12-15 Respira Therapeutics, Inc. Inhalador de polvo seco
JP5672449B2 (ja) * 2011-01-14 2015-02-18 ニプロ株式会社 粉体噴射装置
US10092552B2 (en) 2011-01-31 2018-10-09 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
EP2489663A1 (en) 2011-02-16 2012-08-22 Almirall, S.A. Compounds as syk kinase inhibitors
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
EP2518071A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Imidazopyridine derivatives as PI3K inhibitors
EP2518070A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Pyrrolotriazinone derivatives as PI3K inhibitors
EP2527344A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases
EP2526945A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. New CRTH2 Antagonists
EP2548876A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists
EP2548863A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists.
EP2554544A1 (en) 2011-08-01 2013-02-06 Almirall, S.A. Pyridin-2(1h)-one derivatives as jak inhibitors
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2592077A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
EP2592078A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
EP2647627A1 (en) 2012-04-02 2013-10-09 Almirall, S.A. Salts of 5-[(1r)-2-({2-[4-(2,2-difluoro-2-phenylethoxy)phenyl] ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1h)-one.
EP2666465A1 (en) 2012-05-25 2013-11-27 Almirall, S.A. Novel dosage and formulation
EP2668941A1 (en) 2012-05-31 2013-12-04 Almirall, S.A. Novel dosage form and formulation of abediterol
WO2014060431A1 (en) 2012-10-16 2014-04-24 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
EP2738172A1 (en) 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
BR112015013628A2 (pt) 2012-12-18 2017-07-11 Almirall Sa derivados de carbamato de ciclo-hexila e quinuclidinila tendo atividades agonista adrenérgica de beta2 e antagonista muscarínica de m3
UY35332A (es) 2013-02-15 2014-11-28 Almirall Sa Derivados de pirrolotriazina como inhibidores de pi3k
US8920364B2 (en) 2013-02-28 2014-12-30 Medtronic Xomed, Inc. Biomaterial delivery device
US8845578B2 (en) 2013-02-28 2014-09-30 Medtronic Xomed, Inc. Biomaterial delivery device
EP2848615A1 (en) 2013-07-03 2015-03-18 Almirall, S.A. New pyrazole derivatives as CRAC channel modulators
ES3010397T3 (en) 2013-07-31 2025-04-02 Avalyn Pharma Inc Aerosol tyrosine kinase inhibitor compounds and uses thereof
WO2015091285A1 (en) 2013-12-19 2015-06-25 Almirall S.A. Dosage formulation comprising salmeterol and fluticasone propionate
AU2015204558B2 (en) 2014-01-10 2020-04-30 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
EP3838317A1 (en) 2015-01-14 2021-06-23 Respira Therapeutics, Inc. Dry powder inhaler
US10214509B2 (en) 2015-04-21 2019-02-26 Almirall, S.A. Amino-substituted heterocyclic derivatives as sodium channel inhibitors
WO2016202800A1 (en) 2015-06-16 2016-12-22 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
WO2017076990A1 (en) 2015-11-05 2017-05-11 Almirall, S.A. Addition salts of n-[4-(4-{[(1s)-1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-1h-indol-6-yl]sulfamide
KR20190014288A (ko) 2017-08-01 2019-02-12 주식회사 디에이피 수직형 로더 제어 방법
TW201919682A (zh) 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 活化Ｎｒｆ２路徑的新穎化合物
US20210008305A1 (en) * 2018-03-09 2021-01-14 Health Research, Inc. Induction spacer for inhaler
AU2020283485A1 (en) * 2019-05-24 2022-01-27 Pure Scientific Technologies, Inc. Dual metered inhaler
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3027897A (en) * 1959-07-23 1962-04-03 Carofiglio Louis Edward Nasal inhaler
FR2224175B1 (it) * 1973-04-04 1978-04-14 Isf Spa
US3971377A (en) * 1974-06-10 1976-07-27 Alza Corporation Medicament dispensing process for inhalation therapy
GB1521000A (en) * 1975-06-13 1978-08-09 Syntex Puerto Rico Inc Inhalation device
GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
DE2926659A1 (de) * 1979-07-02 1981-01-15 Kaiser Richard Schnupfgeraet
US4274403A (en) * 1979-08-29 1981-06-23 Struve Roger L Inhaler
ATE23272T1 (de) * 1981-07-08 1986-11-15 Draco Ab Pulverinhalator.
US4570630A (en) * 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
FI69963C (fi) * 1984-10-04 1986-09-12 Orion Yhtymae Oy Doseringsanordning
US4739754A (en) * 1986-05-06 1988-04-26 Shaner William T Suction resistant inhalator
IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli

Also Published As

Publication number Publication date
SI9012031A (en) 1997-10-31
EP0424790B1 (en) 1993-08-04
IL96061A (en) 1994-08-26
HRP931068B1 (en) 1998-02-28
IT8922172A0 (it) 1989-10-27
AU6498790A (en) 1991-05-02
IT8922172A1 (it) 1991-04-27
RU1837897C (ru) 1993-08-30
US5033463A (en) 1991-07-23
KR910007553A (ko) 1991-05-30
EP0424790A3 (en) 1991-11-21
DK0424790T3 (da) 1993-12-13
KR970009719B1 (ko) 1997-06-17
EP0424790A2 (en) 1991-05-02
ATE92349T1 (de) 1993-08-15
NO176468B (no) 1995-01-02
CA2028192C (en) 1995-01-10
FI905163A0 (fi) 1990-10-19
JPH03184563A (ja) 1991-08-12
HRP931068A2 (en) 1995-02-28
NO176468C (no) 1995-04-12
DE69002581D1 (de) 1993-09-09
NO904661L (no) 1991-04-29
IL96061A0 (en) 1991-07-18
DE69002581T2 (de) 1993-11-25
NZ235809A (en) 1993-04-28
FI100306B (fi) 1997-11-14
YU203190A (sh) 1994-04-05
CA2028192A1 (en) 1991-04-28
AU625927B2 (en) 1992-07-16
YU47804B (sr) 1996-01-09
ES2044365T3 (es) 1994-01-01
ZA908563B (en) 1991-08-28
NO904661D0 (no) 1990-10-26
TR24793A (tr) 1992-05-01
JP2515175B2 (ja) 1996-07-10

Similar Documents

Publication Publication Date Title
IT1237118B (it) Inalatore multidose per farmaci in polvere.
DE69203541D1 (de) Einblasgerät für Mehrfachdosierungen von pulverförmigen Medikamenten.
DE69101600D1 (de) Inhalationsvorrichtung zur mehrfachen Ausgabe von Einzeldosen pulverförmiger Arzneimittel.
IL81368A0 (en) Medical dosing device for discharge of atomized medicament for inhalation air
NO992941D0 (no) Medikamentavgivelse og -emballering
PT94195A (pt) Dispositivo para a administracao por inalacao de medicamentos
EP0640354A2 (en) Whirl chamber powder inhaler
ATE79284T1 (de) Zur vollstaendigen entleerung der kapsel geeigneter inhalator.
HK67589A (en) Devices for administering medicaments to patients
FR2521859B1 (fr) Dispositif a vessie d'expulsion destine notamment a l'administration de medicaments
IE40616B1 (en) Apparatus for dispensing dosages of powdered medicaments by inhalation
DE69002800D1 (de) Wegwerfvorrichtung zur inhalation von arzneimitteln.
FR2658487B1 (fr) Dispositif pour nebuliser un medicament constitue d'un melange a former au moment de l'emission.
ZA87409B (en) Medical dosing device for discharge of atomized medicament for inhalation air
PT84193B (en) Medical dosing device for discharge of atomized medicament for inhalation air
ES234534U (es) Aspirador bucal para medicamentos en forma farmaceutica de polvo.

Legal Events

Date Code Title Description
0001 Granted