KR960701672A - 건조 분말 흡입기의 약제 캐리어(dry powder inhalator medicament carrier) - Google Patents

건조 분말 흡입기의 약제 캐리어(dry powder inhalator medicament carrier) Download PDF

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Publication number
KR960701672A
KR960701672A KR1019950703713A KR19950703713A KR960701672A KR 960701672 A KR960701672 A KR 960701672A KR 1019950703713 A KR1019950703713 A KR 1019950703713A KR 19950703713 A KR19950703713 A KR 19950703713A KR 960701672 A KR960701672 A KR 960701672A
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South Korea
Prior art keywords
carrier
pharmaceutical carrier
gap
dry powder
pharmaceutical
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KR1019950703713A
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English (en)
Inventor
파울 뮬하우저
제프리 카르그
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윌리엄 피. 알트만
테낙스 코포레이션
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Publication of KR960701672A publication Critical patent/KR960701672A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type

Abstract

직물 또는 부직물 스크린 메쉬 디스크에는 원주 방향으로 간격을 두고 분말로 된 약제 도우스가 충만되어 있다. 상기 디스크는 선택적으로 표시가 되어 있어 흡입기에 있는 상부 및 하부 압력판의 한쌍의 구멍 사이에 충만된 약제 도우스가 차례로 존재하게 된다. 상기 압력판과 봉합된 스크린 메쉬에 있는 상기 구멍을 통해서 공기가 밀고 나가게 되어 분말로 된 약제를 연행시킨 후 사용자인 환자에 의해 마우스피스를 통해서 흡입되게 된다. 상기 분말로 된 약제는 스크린 메쉬에 충만되어 있기 때문에 상기 약제를 에어졸로 분무하도록 하기 위해 메쉬 하부조직에 대해 프레스하고 이를 통해서 지나가게 되는데, 따라서 상기 약재는 흡입시 장점을 최대로 살리기 위해 적당한 입자 크기로 존재하게 되므로 상기 메쉬에 충돌하는 공기와 상기 분말로 된 약제는 상기 약제를 세분시키게 될 것이다.

Description

건조 분발 흡입기의 약제 캐리어(DRY POWDER INHALATOR MEDICAMENT CARRIER)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 흡입기에서 본 발명의 건조 분말 약제 캐리어를 사용하는 방식을 예시하기 위한 개략도이다.

Claims (14)

  1. 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어에 있어서, 여러개의 빈틈을 포함하는 적어도 하나의 부위, 상기 캐리어의 한 부위인 상기 빈틈에 매립된 미리 정해진 적어도 하나의 분말 약제 도우스 및 상기 부위를 통해서 인가된 공기 호흡에 연행되게 하기 위해 상기 캐리어의 상기 한 부위에 있는 여러개의 상기 빈틈 사이의 공간을 가로지르고 동여 매는 것으로 이루어지는 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  2. 제1항에 있어서, 상기 캐리어는 실크 스크린으로 형성된 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  3. 제1항에 있어서, 상기 캐리어는 금속으로 헝성된 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  4. 제1항에 있어서, 상기 캐리어는 세라믹 재질로 형성된 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  5. 제1항에 있어서, 상기 캐리어는 직물 섬유로 형성된 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  6. 제1항에 있어서, 상기 캐리어는 부직물 섬유로 형성된 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  7. 제1항에 있어서, 상기 캐리어의 빈틈에 매립된 낱개로 되어 있는 다수의 미리 정해진 약제 도우스를 포함하는 건조 분말 호합 활성 흡입기 장치에 사용하기 위한 약재 캐리어.
  8. 제7항에 있어서, 상기 날개의 약제 도우스는 상기 캐리어의 원주를 따라 간격을 두고 상기 캐리어의 빈틈에 매립되어 있는 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  9. 제8항에 있어서, 상기 캐리어에 있는 빈틈은 일반적으로 평면도에서 정방형인 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  10. 제7항에 있어서, 상기 빈틈은 대략 0.004 내지 0.125인치 제곱인 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  11. 제1항에 있어서, 상기 캐리어에 매립된 상기 약제 도우스는 직경이 대략 0.030 내지 0.250인치 그리고 두께가 대략 0.002 내지 0.1인치인 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  12. 제1항에 있어서, 상기 빈틈은 상기 캐리어의 깊이 전체에 걸쳐 균일한 단면을 가지는 건조 분말 호흡활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  13. 제12항에 있어서, 상기 빈틈은 일반적으로 평면도에서 장방형인 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
  14. 제1항에 있어서, 상기 부위에 있는 빈틈은 그 사이에 있는 공간보다 큰 건조 분말 호흡 활성 흡입기 장치에 사용하기 위한 약제 캐리어.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950703713A 1993-03-03 1994-02-28 건조 분말 흡입기의 약제 캐리어(dry powder inhalator medicament carrier) KR960701672A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2596493A 1993-03-03 1993-03-03
US08/025,964 1993-03-03
PCT/US1994/001852 WO1994020164A1 (en) 1993-03-03 1994-02-28 Dry powder inhalator medicament carrier

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KR960701672A true KR960701672A (ko) 1996-03-28

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Country Link
US (1) US5460173A (ko)
EP (1) EP0691864A4 (ko)
JP (1) JPH08507452A (ko)
KR (1) KR960701672A (ko)
CN (1) CN1119833A (ko)
AU (1) AU684754B2 (ko)
BR (1) BR9405842A (ko)
CA (1) CA2157584C (ko)
FI (1) FI954098A0 (ko)
HU (1) HU216405B (ko)
NO (1) NO953388L (ko)
NZ (1) NZ262807A (ko)
WO (1) WO1994020164A1 (ko)

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NZ262807A (en) 1997-11-24
HU216405B (hu) 1999-06-28
CA2157584C (en) 1999-05-04
CN1119833A (zh) 1996-04-03
EP0691864A4 (en) 1996-07-03
BR9405842A (pt) 1996-01-16
JPH08507452A (ja) 1996-08-13
NO953388D0 (no) 1995-08-29
AU684754B2 (en) 1998-01-08
CA2157584A1 (en) 1994-09-15
EP0691864A1 (en) 1996-01-17
HU9502612D0 (en) 1995-11-28
US5460173A (en) 1995-10-24
FI954098A (fi) 1995-09-01
AU6270194A (en) 1994-09-26
WO1994020164A1 (en) 1994-09-15
NO953388L (no) 1995-08-29
HUT76900A (en) 1997-12-29
FI954098A0 (fi) 1995-09-01

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