JP6980380B2 - 短縮ガイドＲＮＡ（ｔｒｕ−ｇＲＮＡ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大 - Google Patents

短縮ガイドＲＮＡ（ｔｒｕ−ｇＲＮＡ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大 Download PDF

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JP6980380B2
JP6980380B2 JP2016502976A JP2016502976A JP6980380B2 JP 6980380 B2 JP6980380 B2 JP 6980380B2 JP 2016502976 A JP2016502976 A JP 2016502976A JP 2016502976 A JP2016502976 A JP 2016502976A JP 6980380 B2 JP6980380 B2 JP 6980380B2
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JP2016512691A (ja
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ジョン，ジェー．キース
ディー． サンダー，ジェフリー
フ，ヤンファン
メーダー，モーガン
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ザ ジェネラル ホスピタル コーポレイション
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JP2016502976A 2013-03-15 2014-03-14 短縮ガイドＲＮＡ（ｔｒｕ−ｇＲＮＡ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大 Active JP6980380B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201361799647P 2013-03-15 2013-03-15
US61/799,647 2013-03-15
US201361838148P 2013-06-21 2013-06-21
US201361838178P 2013-06-21 2013-06-21
US61/838,178 2013-06-21
US61/838,148 2013-06-21
US201361921007P 2013-12-26 2013-12-26
US61/921,007 2013-12-26
PCT/US2014/029068 WO2014144592A2 (en) 2013-03-15 2014-03-14 Using truncated guide rnas (tru-grnas) to increase specificity for rna-guided genome editing

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JP2020055863A Division JP7053706B2 (ja) 2013-03-15 2020-03-26 短縮ガイドＲＮＡ（ｔｒｕ－ｇＲＮＡ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大

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JP2016512691A JP2016512691A (ja) 2016-05-09
JP2016512691A5 JP2016512691A5 (enExample) 2017-04-20
JP6980380B2 true JP6980380B2 (ja) 2021-12-15

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JP2016502976A Active JP6980380B2 (ja) 2013-03-15 2014-03-14 短縮ガイドＲＮＡ（ｔｒｕ−ｇＲＮＡ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大
JP2016502406A Active JP6657069B2 (ja) 2013-03-15 2014-03-14 特定のゲノム遺伝子座へのゲノムおよびエピゲノム調節タンパク質のｒｎａ誘導型標的化
JP2016502853A Active JP6622183B2 (ja) 2013-03-15 2014-03-14 ＲＮＡ誘導型ＦｏｋＩヌクレアーゼ（ＲＦＮ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大
JP2019176599A Active JP6960438B2 (ja) 2013-03-15 2019-09-27 特定のゲノム遺伝子座へのゲノムおよびエピゲノム調節タンパク質のｒｎａ誘導型標的化
JP2019210428A Active JP6878554B2 (ja) 2013-03-15 2019-11-21 ＲＮＡ誘導型ＦｏｋＩヌクレアーゼ（ＲＦＮ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大
JP2020055863A Active JP7053706B2 (ja) 2013-03-15 2020-03-26 短縮ガイドＲＮＡ（ｔｒｕ－ｇＲＮＡ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大
JP2021075869A Active JP7126588B2 (ja) 2013-03-15 2021-04-28 ＲＮＡ誘導型ＦｏｋＩヌクレアーゼ（ＲＦＮ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大
JP2021138479A Pending JP2021192624A (ja) 2013-03-15 2021-08-27 特定のゲノム遺伝子座へのゲノムおよびエピゲノム調節タンパク質のｒｎａ誘導型標的化
JP2022056499A Active JP7379572B2 (ja) 2013-03-15 2022-03-30 短縮ガイドＲＮＡ（ｔｒｕ－ｇＲＮＡ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大
JP2023011473A Withdrawn JP2023061983A (ja) 2013-03-15 2023-01-30 特定のゲノム遺伝子座へのゲノムおよびエピゲノム調節タンパク質のｒｎａ誘導型標的化
JP2023186663A Pending JP2024012446A (ja) 2013-03-15 2023-10-31 短縮ガイドＲＮＡ（ｔｒｕ－ｇＲＮＡ）を用いたＲＮＡ誘導型ゲノム編集の特異性の増大

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US20160024523A1 (en) 2016-01-28
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IL289396A (en) 2022-02-01
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US11634731B2 (en) 2023-04-25
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ZA201506814B (en) 2018-11-28
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AU2020207840A1 (en) 2020-08-13
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