JP5667051B2 - カラー内視鏡検査のための装置 - Google Patents
カラー内視鏡検査のための装置 Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00163—Optical arrangements
- A61B1/00172—Optical arrangements with means for scanning
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- A—HUMAN NECESSITIES
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- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
- A61B1/044—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for absorption imaging
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- A—HUMAN NECESSITIES
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- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
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- A—HUMAN NECESSITIES
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
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- G—PHYSICS
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- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0256—Compact construction
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/12—Generating the spectrum; Monochromators
- G01J3/18—Generating the spectrum; Monochromators using diffraction elements, e.g. grating
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
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- G—PHYSICS
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- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
- G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
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- G02B23/2423—Optical details of the distal end
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
- G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
- G02B23/2407—Optical details
- G02B23/2461—Illumination
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
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- Immunology (AREA)
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- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Instruments For Viewing The Inside Of Hollow Bodies (AREA)
Description
本出願は、2008年7月14日出願の米国特許出願第61/080,534号と関連し、その出願の優先権を主張するものであり、かつその米国出願のすべての開示は引用することにより本明細書の一部である。
例えば、図8Aは、赤光800,緑光810,および青光815を運ぶ、3つのシングルまたはマルチモードの光ファイバを例示的に用いた、例示的な実施態様を叙述している。ファイバは、横方向にオフセットの状態で構成されうる。光は、ファイバ800、810および/または815のいずれかによって検出されうるか、または、光はさらに、プローブ805、806内に存在できるシングルモードまたはマルチモードの他のファイバによって検出することもできる。図8Bは、赤の導波性領域820、緑の導波性領域825および青の導波性領域830を含む単一のファイバを含む他の例示的な実施態様を示している。光は、ファイバの、他のクラッドまたは導波性領域であると考えられる、他の導波性領域835から集められうる。
一つの例示的な実施において、ラインスキャンカメラが、例えば2次元10ビット単色像(例えば、約2048×500ピクセル/像)を作ることができる。暗電流雑音レベルまたはそれ以下のピクセル強度を、最初にゼロに設定できる。次いで、原画像を、赤、緑および青色を表す、3つの単色像(500×500ピクセル/像)に分割できる。各スペクトルコード化ラインは、光源および光学構成要素の光スループット変化のための不均一性を補償され、そして以下の処理によってガンマ補償されることができる。色C(Cは、赤、緑または青でありうる)のための分割されたイメージのスペクトルコード化されたライン上のi’番のピクセルにおける10ビットのグレースケール強度Iは、以下の式により、8ビットグレースケール値pへと変換できる。
p(i,C)=pw[I(i,C)/Iw(i,C)]1/2.2
ここで、pwは、ホワイトの参照カード(例えば、Gretag Macbeth(登録商標) Color Checker(登録商標) White balanceカード、X−Rite社、米国ミシガン州;OD=0.05)のための参照8ビットグレースケール値であり、Iwは、ホワイトの参照カードのために測定された10ビットグレースケール強度である。参照スペクトルIwは、ホワイトの参照カードを前もってイメージングすることにより得ることができ、そしてpwは、製造業者から提供された参照値に合わせて243に設定できる。次いで、3つの加工された8ビットグレースケールイメージは、組み合わされ、赤、緑および青のチャンネルによって併合することにより、24ビットのカラーイメージを形成する。
Claims (11)
- 電磁放射を構造物に提供するための装置であって、
互いに少なくとも部分的に区別される波長をもつ第1及び第2の電磁放射が、そこを通って提供されるように構成された少なくとも2つの導波路を含む第一の構成と、
前記電磁放射を受け、前記それぞれの電磁放射に関連した少なくとも2つに分散された電磁放射を、前記構造物の少なくとも一つの領域に送るように構成された分散用の第二の構成と、を有し、
前記少なくとも2つの導波路は、前記第二の構成において前記第2の電磁放射が前記第1の電磁放射とは(i)少なくとも部分的に異なった角度にておよび/または(ii)少なくとも部分的に異なる位置にて受けとられて、前記構造物上において前記分散された放射が少なくとも部分的に重なるように、前記分散用の構成に対して少なくとも構造的にまたは空間的に配置されていることを特徴とする装置。 - 前記少なくとも2つの導波路が、互いに空間的にオフセットの位置になるように空間配置されていることを特徴とする請求項1に記載の装置。
- 前記少なくとも2つの導波路が、該導波路から出る個々の電磁放射が互いに異なった角度になるように構成されていることを特徴とする請求項1または2に記載の装置。
- 前記分散用の構成が少なくとも一つのグリズムまたは回折格子を含むことを特徴とする請求項1または2に記載の装置。
- 前記分散用の構成が、レンズを含むことを特徴とする請求項1または2に記載の装置。
- 前記少なくとも一つの導波路または分散用の構成が、前記構造物に対して回転するように構成されていることを特徴とする請求項1または2に記載の装置。
- 前記少なくとも一つの導波路が、少なくとも一つの(i)シングルモードファイバ、(ii)マルチモードファイバ、(iii)マルチクラッドファイバ、または(iv)ファイバ束内のファイバであることを特徴とする請求項1または2に記載の装置。
- さらに、前記分散用の第二の構成を通じて構造物から提供されるさらなる電磁放射を受けるように構成された第三の構成を有し、
前記第三の構成は、前記さらなる電磁放射を受けるさらなる導波路を含み、かつ、前記さらなる電磁放射は、分散された電磁波と関連していることを特徴とする請求項1または2に記載の装置。 - 少なくとも一つのさらなる導波路が、少なくとも一つの(i)シングルモードファイバ、(ii)マルチモードファイバ、(iii)マルチクラッドファイバ、または(iv)ファイバ束内のファイバであることを特徴とする請求項8に記載の装置。
- 前記分散用の第二の構成は、受けた電磁放射に基づいてさらなる個々の電磁放射を作り出すように構成されており、
さらに、第二の電磁放射を受けるように構成されている少なくとも2つのさらなる導波路を含む特別の構成を有し、
前記少なくとも2つのさらなる導波路の各々は、前記分散用の第二の構成に対して、波長に応じて前記さらなる個々の電磁放射の区別された一つの受取りを容易にするように、少なくとも構造化または空間的に配置されることを特徴とする請求項1または2に記載の装置。 - 電磁放射を構造物に提供するための装置であって、
互いに少なくとも部分的に区別される波長をもつ第1及び第2の電磁放射を含む少なくとも2つの個別の電磁放射がそこを通って提供されるように構成された少なくとも2つの導波路を備えた第一の構成、ここで、前記第1の電磁放射は第1導波路に提供され及び前記第2の電磁放射は第2導波路に提供される、および
前記電磁放射を受け、前記個別の電磁放射に関連した少なくとも2つの分散された電磁放射を、前記構造物の少なくとも一つの領域に送るように構成された分散用の第二の構成と、を有し、
前記少なくとも2つの導波路は、前記第二の構成において前記第2の電磁放射が前記第1の電磁放射とは(i)少なくとも部分的に異なった角度にておよび/または(ii)少なくとも部分的に異なる位置にて受けとられて、前記構造物上において前記分散された放射が波長の関数である前記構造物上の横断位置にて受けとられるように、前記分散用の構成に対して少なくとも構造的にまたは空間的に配置されていることを特徴とする装置。
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US8053408P | 2008-07-14 | 2008-07-14 | |
US61/080,534 | 2008-07-14 | ||
PCT/US2009/050553 WO2010009136A2 (en) | 2008-07-14 | 2009-07-14 | Apparatus and methods for color endoscopy |
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JP2013246439A Active JP5829667B2 (ja) | 2008-07-14 | 2013-11-28 | カラー内視鏡検査のための装置 |
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US (2) | US9254089B2 (ja) |
EP (1) | EP2309923B1 (ja) |
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WO (1) | WO2010009136A2 (ja) |
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JP2011527930A (ja) | 2011-11-10 |
JP5829667B2 (ja) | 2015-12-09 |
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US20110237892A1 (en) | 2011-09-29 |
WO2010009136A2 (en) | 2010-01-21 |
EP2309923A2 (en) | 2011-04-20 |
EP2309923B1 (en) | 2020-11-25 |
JP2014064935A (ja) | 2014-04-17 |
WO2010009136A3 (en) | 2010-04-08 |
US10835110B2 (en) | 2020-11-17 |
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