AU2519892A - Optical histochemical analysis, in vivo detection and real-time guidance for ablation of abnormal tissues using a raman spectroscopic detection system - Google Patents

Optical histochemical analysis, in vivo detection and real-time guidance for ablation of abnormal tissues using a raman spectroscopic detection system

Info

Publication number
AU2519892A
AU2519892A AU25198/92A AU2519892A AU2519892A AU 2519892 A AU2519892 A AU 2519892A AU 25198/92 A AU25198/92 A AU 25198/92A AU 2519892 A AU2519892 A AU 2519892A AU 2519892 A AU2519892 A AU 2519892A
Authority
AU
Australia
Prior art keywords
ablation
real
optical
raman spectroscopic
histochemical analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU25198/92A
Inventor
Douglas C.B. Redd
Original Assignee
Douglas C.B. Redd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US74769891A priority Critical
Priority to US747698 priority
Application filed by Douglas C.B. Redd filed Critical Douglas C.B. Redd
Publication of AU2519892A publication Critical patent/AU2519892A/en
Application status is Abandoned legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0059Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0059Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0059Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0091Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/43Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312Breast evaluation or disorder diagnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00022Sensing or detecting at the treatment site
    • A61B2017/00057Light
    • A61B2017/00061Light spectrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0059Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A61B5/0086Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infra-red radiation
AU25198/92A 1991-08-20 1992-08-20 Optical histochemical analysis, in vivo detection and real-time guidance for ablation of abnormal tissues using a raman spectroscopic detection system Abandoned AU2519892A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US74769891A true 1991-08-20 1991-08-20
US747698 1991-08-20

Publications (1)

Publication Number Publication Date
AU2519892A true AU2519892A (en) 1993-03-16

Family

ID=25006244

Family Applications (1)

Application Number Title Priority Date Filing Date
AU25198/92A Abandoned AU2519892A (en) 1991-08-20 1992-08-20 Optical histochemical analysis, in vivo detection and real-time guidance for ablation of abnormal tissues using a raman spectroscopic detection system

Country Status (2)

Country Link
AU (1) AU2519892A (en)
WO (1) WO1993003672A1 (en)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011624A2 (en) * 1993-10-29 1995-05-04 Feld Michael S A raman endoscope
US5991653A (en) * 1995-03-14 1999-11-23 Board Of Regents, The University Of Texas System Near-infrared raman spectroscopy for in vitro and in vivo detection of cervical precancers
US5697373A (en) * 1995-03-14 1997-12-16 Board Of Regents, The University Of Texas System Optical method and apparatus for the diagnosis of cervical precancers using raman and fluorescence spectroscopies
US5699795A (en) * 1995-03-31 1997-12-23 Board Of Regents, The University Of Texas System Optical probe for the detection of cervical neoplasia using fluorescence spectroscopy and apparatus incorporating same
US5733739A (en) * 1995-06-07 1998-03-31 Inphocyte, Inc. System and method for diagnosis of disease by infrared analysis of human tissues and cells
US5891619A (en) * 1997-01-14 1999-04-06 Inphocyte, Inc. System and method for mapping the distribution of normal and abnormal cells in sections of tissue
US6228076B1 (en) * 1999-01-09 2001-05-08 Intraluminal Therapeutics, Inc. System and method for controlling tissue ablation
US6377841B1 (en) 2000-03-31 2002-04-23 Vanderbilt University Tumor demarcation using optical spectroscopy
NZ522128A (en) * 2000-03-31 2003-08-29 Rita Medical Systems Inc Tissue biopsy and treatment apparatus and method
EP1434522B1 (en) 2000-10-30 2010-01-13 The General Hospital Corporation Optical systems for tissue analysis
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
WO2002088684A1 (en) 2001-04-30 2002-11-07 The General Hospital Corporation Method and apparatus for improving image clarity and sensitivity in optical coherence tomography using dynamic feedback to control focal properties and coherence gating
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US6980299B1 (en) 2001-10-16 2005-12-27 General Hospital Corporation Systems and methods for imaging a sample
US7647092B2 (en) 2002-04-05 2010-01-12 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
JP4041421B2 (en) * 2003-03-25 2008-01-30 株式会社町田製作所 Raman probe and Raman scattering measurement apparatus using the same
CA2519937C (en) 2003-03-31 2012-11-20 Guillermo J. Tearney Speckle reduction in optical coherence tomography by path length encoded angular compounding
EP2278287B1 (en) 2003-10-27 2016-09-07 The General Hospital Corporation Method and apparatus for performing optical imaging using frequency-domain interferometry
US7697576B2 (en) 2004-05-05 2010-04-13 Chem Image Corporation Cytological analysis by raman spectroscopic imaging
WO2006014392A1 (en) 2004-07-02 2006-02-09 The General Hospital Corporation Endoscopic imaging probe comprising dual clad fibre
JP5053845B2 (en) 2004-08-06 2012-10-24 ザ ジェネラル ホスピタル コーポレイション The method for determining at least one position in a sample using optical coherence tomography, system and software device
EP2272420B1 (en) 2004-08-24 2013-06-19 The General Hospital Corporation Apparatus for imaging of vessel segments
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EP2329759B1 (en) 2004-09-29 2014-03-12 The General Hospital Corporation System and method for optical coherence imaging
US20060229515A1 (en) * 2004-11-17 2006-10-12 The Regents Of The University Of California Fiber optic evaluation of tissue modification
WO2006058346A1 (en) 2004-11-29 2006-06-01 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
ES2337497T3 (en) 2005-04-28 2010-04-26 The General Hospital Corporation Evaluation of characteristics of the image of an anatomical structure images of optical coherence tomography.
EP1889037A2 (en) 2005-06-01 2008-02-20 The General Hospital Corporation Apparatus, method and system for performing phase-resolved optical frequency domain imaging
CN101238347B (en) 2005-08-09 2011-05-25 通用医疗公司 Apparatus, methods and storage medium for performing polarization-based quadrature demodulation in optical coherence tomography
KR20080066705A (en) 2005-09-29 2008-07-16 더 제너럴 하스피탈 코포레이션 Method and apparatus for method for viewing and analyzing of one or more biological smaples with progressively increasing resolutions
US8145018B2 (en) 2006-01-19 2012-03-27 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements
WO2007084995A2 (en) 2006-01-19 2007-07-26 The General Hospital Corporation Methods and systems for optical imaging of epithelial luminal organs by beam scanning thereof
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JP5519152B2 (en) 2006-02-08 2014-06-11 ザ ジェネラル ホスピタル コーポレイション Apparatus for acquiring information related to anatomical sample using optical microscopy
JP2009527770A (en) 2006-02-24 2009-07-30 ザ ジェネラル ホスピタル コーポレイション Angle-resolved Fourier domain optical coherence tomography performing method and system
EP2015669A2 (en) 2006-05-10 2009-01-21 The General Hospital Corporation Processes, arrangements and systems for providing frequency domain imaging of a sample
US8417323B2 (en) 2006-05-30 2013-04-09 Koninklijke Philips Electronics N.V. Apparatus for depth-resolved measurements of properties of tissue
WO2008049118A2 (en) 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
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CN102015020A (en) * 2008-05-09 2011-04-13 休·贝克曼 Medical device for diagnosing and treating anomalous tissue and method for doing the same
JP5795531B2 (en) 2008-06-20 2015-10-14 ザ ジェネラル ホスピタル コーポレイション Fused fiber optic coupler structure, and methods of use thereof
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US8253936B2 (en) 2008-08-08 2012-08-28 Chemimage Corporation Raman characterization of transplant tissue
US8416405B2 (en) 2008-08-08 2013-04-09 Chemimage Corporation Raman chemical imaging of implantable drug delivery devices
EP3330696A1 (en) 2008-12-10 2018-06-06 The General Hospital Corporation Systems, apparatus and methods for extending imaging depth range of optical coherence tomography through optical sub-sampling
WO2010091190A2 (en) 2009-02-04 2010-08-12 The General Hospital Corporation Apparatus and method for utilization of a high-speed optical wavelength tuning source
US9351642B2 (en) 2009-03-12 2016-05-31 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measurement at least one mechanical property of tissue using coherent speckle technique(s)
WO2010144081A1 (en) * 2009-06-10 2010-12-16 University Of Utah Research Foundation Apparatus for raman spectroscopy having an optical fiber probe
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US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
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JP5778762B2 (en) 2010-05-25 2015-09-16 ザ ジェネラル ホスピタル コーポレイション Apparatus and method for spectral analysis of optical coherence tomography images
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KR20130056886A (en) * 2010-06-25 2013-05-30 노스이스턴 유니버시티 Method for analyzing biological specimens by spectral imaging
US9025850B2 (en) 2010-06-25 2015-05-05 Cireca Theranostics, Llc Method for analyzing biological specimens by spectral imaging
US9510758B2 (en) 2010-10-27 2016-12-06 The General Hospital Corporation Apparatus, systems and methods for measuring blood pressure within at least one vessel
JP2014523536A (en) 2011-07-19 2014-09-11 ザ ジェネラル ホスピタル コーポレイション System for providing a polarization mode dispersion compensation in an optical coherence tomography method, apparatus and computer-accessible medium
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WO2013148306A1 (en) 2012-03-30 2013-10-03 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
WO2014031748A1 (en) 2012-08-22 2014-02-27 The General Hospital Corporation System, method, and computer-accessible medium for fabrication minature endoscope using soft lithography
CN104797210A (en) * 2012-11-09 2015-07-22 Ams研究公司 Surgical laser tool
AU2013361366B2 (en) 2012-12-19 2018-10-18 Sloan-Kettering Institute For Cancer Research Multimodal particles, methods and uses thereof
WO2016028749A1 (en) * 2014-08-20 2016-02-25 Memorial Sloan Kettering Cancer Center Raman-triggered ablation/resection systems and methods
US9784681B2 (en) 2013-05-13 2017-10-10 The General Hospital Corporation System and method for efficient detection of the phase and amplitude of a periodic modulation associated with self-interfering fluorescence
EP3021735A4 (en) 2013-07-19 2017-04-19 The General Hospital Corporation Determining eye motion by imaging retina. with feedback
EP3025173A4 (en) 2013-07-26 2017-03-22 The General Hospital Corporation System, apparatus and method utilizing optical dispersion for fourier-domain optical coherence tomography
WO2015105870A1 (en) 2014-01-08 2015-07-16 The General Hospital Corporation Method and apparatus for microscopic imaging
GB201401727D0 (en) * 2014-01-31 2014-03-19 Univ Bristol A low background raman probe for optical biopsy of brain tissue
US10228556B2 (en) 2014-04-04 2019-03-12 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4669467A (en) * 1985-03-22 1987-06-02 Massachusetts Institute Of Technology Mode mixer for a laser catheter

Also Published As

Publication number Publication date
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