JP2014156468A5 - - Google Patents
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- JP2014156468A5 JP2014156468A5 JP2014075501A JP2014075501A JP2014156468A5 JP 2014156468 A5 JP2014156468 A5 JP 2014156468A5 JP 2014075501 A JP2014075501 A JP 2014075501A JP 2014075501 A JP2014075501 A JP 2014075501A JP 2014156468 A5 JP2014156468 A5 JP 2014156468A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- medicament
- treatment
- compound selected
- dimethoxyphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 150000001875 compounds Chemical class 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- IRBAWVGZNJIROV-SFHVURJKSA-N 9-(2-cyclopropylethynyl)-2-[[(2s)-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one Chemical compound C1=C2C3=CC=C(C#CC4CC4)C=C3CCN2C(=O)N=C1OC[C@@H]1COCCO1 IRBAWVGZNJIROV-SFHVURJKSA-N 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 1
- 206010013774 Dry eye Diseases 0.000 claims 1
- 206010014561 Emphysema Diseases 0.000 claims 1
- SIKXWJFYMYNNGL-UHFFFAOYSA-N n-(3,4-dimethoxyphenyl)-4-oxo-1h-quinoline-3-carboxamide Chemical compound C1=C(OC)C(OC)=CC=C1NC(=O)C1=CNC2=CC=CC=C2C1=O SIKXWJFYMYNNGL-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58267604P | 2004-06-24 | 2004-06-24 | |
| US60/582,676 | 2004-06-24 | ||
| US63012704P | 2004-11-22 | 2004-11-22 | |
| US60/630,127 | 2004-11-22 | ||
| US63567404P | 2004-12-13 | 2004-12-13 | |
| US60/635,674 | 2004-12-13 | ||
| US65821905P | 2005-03-03 | 2005-03-03 | |
| US60/658,219 | 2005-03-03 | ||
| US66131105P | 2005-03-11 | 2005-03-11 | |
| US60/661,311 | 2005-03-11 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012050845A Division JP2012107069A (ja) | 2004-06-24 | 2012-03-07 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015135324A Division JP2015172087A (ja) | 2004-06-24 | 2015-07-06 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014156468A JP2014156468A (ja) | 2014-08-28 |
| JP2014156468A5 true JP2014156468A5 (cg-RX-API-DMAC7.html) | 2015-08-20 |
Family
ID=35429349
Family Applications (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007518350A Expired - Lifetime JP4947658B2 (ja) | 2004-06-24 | 2005-06-24 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2011266327A Expired - Lifetime JP5712117B2 (ja) | 2004-06-24 | 2011-12-05 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2011266325A Expired - Lifetime JP5762940B2 (ja) | 2004-06-24 | 2011-12-05 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2011266326A Expired - Lifetime JP5654979B2 (ja) | 2004-06-24 | 2011-12-05 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2012050845A Pending JP2012107069A (ja) | 2004-06-24 | 2012-03-07 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2014075501A Ceased JP2014156468A (ja) | 2004-06-24 | 2014-04-01 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2015135324A Withdrawn JP2015172087A (ja) | 2004-06-24 | 2015-07-06 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2016247687A Expired - Lifetime JP6285004B2 (ja) | 2004-06-24 | 2016-12-21 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007518350A Expired - Lifetime JP4947658B2 (ja) | 2004-06-24 | 2005-06-24 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2011266327A Expired - Lifetime JP5712117B2 (ja) | 2004-06-24 | 2011-12-05 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2011266325A Expired - Lifetime JP5762940B2 (ja) | 2004-06-24 | 2011-12-05 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2011266326A Expired - Lifetime JP5654979B2 (ja) | 2004-06-24 | 2011-12-05 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2012050845A Pending JP2012107069A (ja) | 2004-06-24 | 2012-03-07 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015135324A Withdrawn JP2015172087A (ja) | 2004-06-24 | 2015-07-06 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
| JP2016247687A Expired - Lifetime JP6285004B2 (ja) | 2004-06-24 | 2016-12-21 | Ａｔｐ結合カセットトランスポーターのモジュレーター |
Country Status (25)
Families Citing this family (261)
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| US8354427B2 (en) * | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| ME02799B (me) * | 2004-06-24 | 2018-01-20 | Vertex Pharma | Modulatori ATP-vezujućih kasetnih transportera |
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| SI1945632T1 (sl) | 2005-11-08 | 2014-03-31 | Vertex Pharmaceuticals Incorporated | Heterocikliäśni modulatorji za prenaĺ alce z atp-vezavno kaseto |
| CN101365682A (zh) | 2005-12-08 | 2009-02-11 | 千禧药品公司 | 具有激酶抑制活性的双环化合物 |
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