|
US2128208A
(en)
|
1937-02-27 |
1938-08-23 |
Du Pont |
Alkoxy derivatives of methacrylic acid esters and method of producing them
|
|
CU22545A1
(es)
|
1994-11-18 |
1999-03-31 |
Centro Inmunologia Molecular |
Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico
|
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
EP0092918B1
(en)
|
1982-04-22 |
1988-10-19 |
Imperial Chemical Industries Plc |
Continuous release formulations
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4753894A
(en)
|
1984-02-08 |
1988-06-28 |
Cetus Corporation |
Monoclonal anti-human breast cancer antibodies
|
|
US4943533A
(en)
|
1984-03-01 |
1990-07-24 |
The Regents Of The University Of California |
Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor
|
|
US5128326A
(en)
|
1984-12-06 |
1992-07-07 |
Biomatrix, Inc. |
Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
|
|
US6492107B1
(en)
|
1986-11-20 |
2002-12-10 |
Stuart Kauffman |
Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique
|
|
DE3587814T2
(de)
|
1985-03-30 |
1994-11-10 |
Marc Ballivet |
Verfahren zum erhalten von dns, rns, peptiden, polypeptiden oder proteinen durch dns-rekombinant-verfahren.
|
|
US4980286A
(en)
|
1985-07-05 |
1990-12-25 |
Whitehead Institute For Biomedical Research |
In vivo introduction and expression of foreign genetic material in epithelial cells
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
DE3600905A1
(de)
|
1986-01-15 |
1987-07-16 |
Ant Nachrichtentech |
Verfahren zum dekodieren von binaersignalen sowie viterbi-dekoder und anwendungen
|
|
US4699784A
(en)
|
1986-02-25 |
1987-10-13 |
Center For Molecular Medicine & Immunology |
Tumoricidal methotrexate-antibody conjugate
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
DE3750503T2
(de)
|
1986-10-22 |
1995-02-09 |
Abbott Lab |
Chemilumineszierende Acridinium- und Phenantridiniumsalze.
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
JP3101690B2
(ja)
|
1987-03-18 |
2000-10-23 |
エス・ビィ・２・インコーポレイテッド |
変性抗体の、または変性抗体に関する改良
|
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
|
US4880078A
(en)
|
1987-06-29 |
1989-11-14 |
Honda Giken Kogyo Kabushiki Kaisha |
Exhaust muffler
|
|
WO1989006692A1
(en)
|
1988-01-12 |
1989-07-27 |
Genentech, Inc. |
Method of treating tumor cells by inhibiting growth factor receptor function
|
|
US5006309A
(en)
|
1988-04-22 |
1991-04-09 |
Abbott Laboratories |
Immunoassay device with liquid transfer between wells by washing
|
|
US5089424A
(en)
|
1988-06-14 |
1992-02-18 |
Abbott Laboratories |
Method and apparatus for heterogeneous chemiluminescence assay
|
|
DE68927933T2
(de)
|
1988-09-02 |
1997-08-14 |
Dyax Corp |
Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5241070A
(en)
|
1988-09-26 |
1993-08-31 |
Ciba Corning Diagnostics Corp. |
Nucleophilic polysubstituted aryl acridinium esters and uses thereof
|
|
WO1990005183A1
(en)
|
1988-10-31 |
1990-05-17 |
Immunex Corporation |
Interleukin-4 receptors
|
|
SE462454B
(sv)
|
1988-11-10 |
1990-06-25 |
Pharmacia Ab |
Maetyta foer anvaendning i biosensorer
|
|
FI903489A7
(fi)
|
1988-11-11 |
1990-07-10 |
Medical Res Council |
Yhden osan sisältävät ligandit, näitä ligandeja sisältävät reseptorit, menetelmiä niiden valmistamiseksi sekä ligandien ja reseptorien käytt ö
|
|
US5063081A
(en)
|
1988-11-14 |
1991-11-05 |
I-Stat Corporation |
Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
EP0478627A4
(en)
|
1989-05-16 |
1992-08-19 |
William D. Huse |
Co-expression of heteromeric receptors
|
|
CA2016841C
(en)
|
1989-05-16 |
1999-09-21 |
William D. Huse |
A method for producing polymers having a preselected activity
|
|
CA2016842A1
(en)
|
1989-05-16 |
1990-11-16 |
Richard A. Lerner |
Method for tapping the immunological repertoire
|
|
AU6430190A
(en)
|
1989-10-10 |
1991-05-16 |
Pitman-Moore, Inc. |
Sustained release composition for macromolecular proteins
|
|
CA2071867A1
(en)
|
1989-11-06 |
1991-05-07 |
Edith Mathiowitz |
Method for producing protein microspheres
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
|
AU7247191A
(en)
|
1990-01-11 |
1991-08-05 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
EP1690935A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
JPH05506357A
(ja)
|
1990-05-25 |
1993-09-22 |
ルミニス ピーティーワイ リミテッド |
酵母株同定用マーカー
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
ES2139598T3
(es)
|
1990-07-10 |
2000-02-16 |
Medical Res Council |
Procedimientos para la produccion de miembros de parejas de union especifica.
|
|
CA2090126C
(en)
|
1990-08-02 |
2002-10-22 |
John W. Schrader |
Methods for the production of proteins with a desired function
|
|
CA2048302A1
(en)
|
1990-08-15 |
1992-02-16 |
Victoria P. Meucci |
Solubilization reagent for biological test samples
|
|
US5135875A
(en)
|
1990-08-15 |
1992-08-04 |
Abbott Laboratories |
Protein precipitation reagent
|
|
EP0544809B1
(en)
|
1990-08-24 |
1998-12-16 |
Ixsys, Inc. |
Methods of synthesizing oligonucleotides with random codons
|
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
|
DE69129154T2
(de)
|
1990-12-03 |
1998-08-20 |
Genentech, Inc., South San Francisco, Calif. |
Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
|
|
US5780279A
(en)
|
1990-12-03 |
1998-07-14 |
Genentech, Inc. |
Method of selection of proteolytic cleavage sites by directed evolution and phagemid display
|
|
IE914504A1
(en)
|
1990-12-20 |
1992-07-01 |
Ixsys |
Optimization of binding proteins
|
|
DE69233697T2
(de)
|
1991-03-01 |
2008-01-24 |
Dyax Corp., Cambridge |
Verfahren zur Entwicklung von bindenden Mikroproteinen
|
|
AU658396B2
(en)
|
1991-03-06 |
1995-04-13 |
Merck Patent Gesellschaft Mit Beschrankter Haftung |
Humanized and chimeric monoclonal antibodies
|
|
US6277969B1
(en)
|
1991-03-18 |
2001-08-21 |
New York University |
Anti-TNF antibodies and peptides of human tumor necrosis factor
|
|
US5656272A
(en)
|
1991-03-18 |
1997-08-12 |
New York University Medical Center |
Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies
|
|
DE07012626T1
(de)
|
1991-03-18 |
2010-01-21 |
New York University |
Monoklonale und chimäre Antikörper gegen humanen Tumornekrosefaktor
|
|
PT100379B
(pt)
|
1991-04-10 |
1999-01-29 |
Scripps Research Inst |
Bibliotecas de receptores heterodimericos usando fagomideos
|
|
AU668349B2
(en)
|
1991-04-25 |
1996-05-02 |
Chugai Seiyaku Kabushiki Kaisha |
Reconstituted human antibody against human interleukin 6 receptor
|
|
JPH06507404A
(ja)
|
1991-05-01 |
1994-08-25 |
ヘンリー エム．ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディスン |
感染性の呼吸性疾患の治療方法
|
|
DE69233482T2
(de)
|
1991-05-17 |
2006-01-12 |
Merck & Co., Inc. |
Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
|
|
CA2069530A1
(en)
|
1991-06-03 |
1992-12-04 |
Cass J. Grandone |
Reagent pack for immunoassays
|
|
DE4118120A1
(de)
|
1991-06-03 |
1992-12-10 |
Behringwerke Ag |
Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
JPH07503124A
(ja)
|
1991-06-14 |
1995-04-06 |
ゾーマ・コーポレーション |
微生物によって生産される抗体断片とそれらの複合体
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
DE4122599C2
(de)
|
1991-07-08 |
1993-11-11 |
Deutsches Krebsforsch |
Phagemid zum Screenen von Antikörpern
|
|
JP3540315B2
(ja)
|
1991-09-23 |
2004-07-07 |
メディカル リサーチ カウンシル |
キメラ抗体の製造−組合せアプローチ
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
DE69233528T2
(de)
|
1991-11-25 |
2006-03-16 |
Enzon, Inc. |
Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
|
|
PT1024191E
(pt)
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
|
WO1993011794A1
(en)
|
1991-12-13 |
1993-06-24 |
Xoma Corporation |
Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
|
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
US5912015A
(en)
|
1992-03-12 |
1999-06-15 |
Alkermes Controlled Therapeutics, Inc. |
Modulated release from biocompatible polymers
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5352803A
(en)
|
1992-03-30 |
1994-10-04 |
Abbott Laboratories |
5(6)-methyl substituted fluorescein derivatives
|
|
EP0649533B1
(en)
|
1992-03-30 |
2000-05-10 |
Abbott Laboratories |
Reagents and methods for the detection and quantification of thyroxine in fluid samples
|
|
ES2301158T3
(es)
|
1992-07-24 |
2008-06-16 |
Amgen Fremont Inc. |
Produccion de anticuerpos xenogenicos.
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
ATE139900T1
(de)
|
1992-11-13 |
1996-07-15 |
Idec Pharma Corp |
Therapeutische verwendung von chimerischen und markierten antikörper gegen menschlichen b lymphozyt beschränkter differenzierung antigen für die behandlung von b-zell-lymphoma
|
|
US5934272A
(en)
|
1993-01-29 |
1999-08-10 |
Aradigm Corporation |
Device and method of creating aerosolized mist of respiratory drug
|
|
AU6132994A
(en)
|
1993-02-02 |
1994-08-29 |
Scripps Research Institute, The |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
US6491916B1
(en)
|
1994-06-01 |
2002-12-10 |
Tolerance Therapeutics, Inc. |
Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies
|
|
WO1995001997A1
(en)
*
|
1993-07-09 |
1995-01-19 |
Smithkline Beecham Corporation |
RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN
|
|
WO1995009917A1
(en)
|
1993-10-07 |
1995-04-13 |
The Regents Of The University Of California |
Genetically engineered bispecific tetravalent antibodies
|
|
EP0659766A1
(en)
*
|
1993-11-23 |
1995-06-28 |
Schering-Plough |
Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
|
|
US5565352A
(en)
|
1993-11-24 |
1996-10-15 |
Arch Development Corporation |
Deubiquitinating enzyme: compositions and methods
|
|
JPH09506262A
(ja)
|
1993-12-08 |
1997-06-24 |
ジェンザイム・コーポレイション |
特異的抗体の製造方法
|
|
CA2178590A1
(en)
|
1993-12-10 |
1995-06-15 |
Joan D. Tyner |
Reagents and methods for the detection of methotrexate
|
|
GB9401182D0
(en)
|
1994-01-21 |
1994-03-16 |
Inst Of Cancer The Research |
Antibodies to EGF receptor and their antitumour effect
|
|
ES2201097T3
(es)
|
1994-01-31 |
2004-03-16 |
Trustees Of Boston University |
Bibliotecas de anticuerpos policlonales.
|
|
ZA95960B
(en)
|
1994-03-14 |
1995-10-10 |
Genetics Inst |
Use of interleukin-12 antagonists in the treatment of autoimmune diseases
|
|
HU221001B1
(hu)
|
1994-03-17 |
2002-07-29 |
Merck Patent Gmbh. |
Egyláncú anti-EGFR Fv-k és anti-EGFR ellenanyagok
|
|
IL109632A
(en)
|
1994-05-11 |
2007-03-08 |
Yeda Res & Dev |
Modulators of the function of tnf receptors
|
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
|
AU3272695A
(en)
|
1994-08-12 |
1996-03-07 |
Immunomedics Inc. |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
|
ATE252894T1
(de)
|
1995-01-05 |
2003-11-15 |
Univ Michigan |
Oberflächen-modifizierte nanopartikel und verfahren für ihre herstellung und verwendung
|
|
GB9504344D0
(en)
|
1995-03-03 |
1995-04-19 |
Unilever Plc |
Antibody fragment production
|
|
US6091001A
(en)
|
1995-03-29 |
2000-07-18 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
US6130364A
(en)
|
1995-03-29 |
2000-10-10 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
|
US6019968A
(en)
|
1995-04-14 |
2000-02-01 |
Inhale Therapeutic Systems, Inc. |
Dispersible antibody compositions and methods for their preparation and use
|
|
AU705616B2
(en)
|
1995-04-21 |
1999-05-27 |
Cell Genesys, Inc. |
Generation of large genomic DNA deletions
|
|
CA2219361C
(en)
|
1995-04-27 |
2012-02-28 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US7060808B1
(en)
|
1995-06-07 |
2006-06-13 |
Imclone Systems Incorporated |
Humanized anti-EGF receptor monoclonal antibody
|
|
CA2222231A1
(en)
|
1995-06-07 |
1996-12-19 |
Imclone Systems Incorporated |
Antibody and antibody fragments for inhibiting the growth of tumors
|
|
US6127977A
(en)
|
1996-11-08 |
2000-10-03 |
Cohen; Nathan |
Microstrip patch antenna with fractal structure
|
|
AU710347B2
(en)
|
1995-08-31 |
1999-09-16 |
Alkermes Controlled Therapeutics, Inc. |
Composition for sustained release of an agent
|
|
US5989830A
(en)
|
1995-10-16 |
1999-11-23 |
Unilever Patent Holdings Bv |
Bifunctional or bivalent antibody fragment analogue
|
|
US6090382A
(en)
|
1996-02-09 |
2000-07-18 |
Basf Aktiengesellschaft |
Human antibodies that bind human TNFα
|
|
US6331431B1
(en)
|
1995-11-28 |
2001-12-18 |
Ixsys, Inc. |
Vacuum device and method for isolating periplasmic fraction from cells
|
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
|
ATE239041T1
(de)
|
1996-02-09 |
2003-05-15 |
Basf Ag |
Humane antikörper welche an humanen tnfalpha binden
|
|
US5985320A
(en)
|
1996-03-04 |
1999-11-16 |
The Penn State Research Foundation |
Materials and methods for enhancing cellular internalization
|
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
|
JPH11507843A
(ja)
|
1996-03-28 |
1999-07-13 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
タンパク質の可溶性二価および多価ヘテロ二量体類縁体
|
|
WO1997038102A1
(en)
|
1996-04-04 |
1997-10-16 |
Unilever Plc |
Multivalent and multispecific antigen-binding protein
|
|
US5985309A
(en)
|
1996-05-24 |
1999-11-16 |
Massachusetts Institute Of Technology |
Preparation of particles for inhalation
|
|
US5855913A
(en)
|
1997-01-16 |
1999-01-05 |
Massachusetts Instite Of Technology |
Particles incorporating surfactants for pulmonary drug delivery
|
|
US5874064A
(en)
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
|
US6699658B1
(en)
|
1996-05-31 |
2004-03-02 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
US6986890B1
(en)
|
1996-11-21 |
2006-01-17 |
Kyowa Hakko Kogyo Co., Ltd. |
Anti-human VEGF receptor Flt-1 monoclonal antibody
|
|
EP1972194A1
(en)
|
1996-12-03 |
2008-09-24 |
Amgen Fremont Inc. |
Transgenic mammals having human ig loci including plural vh and vk regions and antibodies produced therefrom
|
|
DE69732306T2
(de)
|
1997-01-16 |
2006-01-12 |
Massachusetts Institute Of Technology, Cambridge |
Zubereitung von partikelhaltigen arzneimitteln zur inhalation
|
|
IL131016A
(en)
|
1997-01-21 |
2004-12-15 |
Gen Hospital Corp |
Selection of proteins using RNA-protein blends
|
|
US7306914B2
(en)
|
1997-01-31 |
2007-12-11 |
Odyssey Thera Inc. |
Protein fragment complementation assays in whole animals applications to drug efficacy, ADME, cancer biology, immunology, infectious disease and gene therapy
|
|
US6057098A
(en)
|
1997-04-04 |
2000-05-02 |
Biosite Diagnostics, Inc. |
Polyvalent display libraries
|
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
DE69829891T2
(de)
|
1997-04-07 |
2005-10-06 |
Genentech, Inc., South San Francisco |
Anti-VEGF Antikörper
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
NZ516848A
(en)
|
1997-06-20 |
2004-03-26 |
Ciphergen Biosystems Inc |
Retentate chromatography apparatus with applications in biology and medicine
|
|
AU8691398A
(en)
|
1997-08-04 |
1999-02-22 |
Ixsys, Incorporated |
Methods for identifying ligand specific binding molecules
|
|
US5989463A
(en)
|
1997-09-24 |
1999-11-23 |
Alkermes Controlled Therapeutics, Inc. |
Methods for fabricating polymer-based controlled release devices
|
|
SE512663C2
(sv)
|
1997-10-23 |
2000-04-17 |
Biogram Ab |
Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
|
|
DK1027439T3
(da)
|
1997-10-27 |
2010-05-10 |
Bac Ip Bv |
Multivalente antigenbindende proteiner
|
|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
KR20010034554A
(ko)
|
1998-03-03 |
2001-04-25 |
레이몬드, 엠. 위티 |
치료제로서의 ｃｄ147 결합 분자
|
|
EP1068356B8
(en)
|
1998-04-03 |
2007-01-03 |
Adnexus Therapeutics, Inc. |
Addressable protein arrays
|
|
US20020029391A1
(en)
|
1998-04-15 |
2002-03-07 |
Claude Geoffrey Davis |
Epitope-driven human antibody production and gene expression profiling
|
|
JP4334141B2
(ja)
|
1998-04-20 |
2009-09-30 |
グリカート バイオテクノロジー アクチェンゲゼルシャフト |
抗体依存性細胞傷害性を改善するための抗体のグリコシル化操作
|
|
ATE370961T1
(de)
|
1998-05-06 |
2007-09-15 |
Genentech Inc |
Reinigung von antikörpern durch ionenaustauschchromatographie
|
|
ES2198922T3
(es)
|
1998-06-24 |
2004-02-01 |
Advanced Inhalation Research, Inc. |
Particulas porosas grandes emitadas por un inhalador.
|
|
US6406921B1
(en)
|
1998-07-14 |
2002-06-18 |
Zyomyx, Incorporated |
Protein arrays for high-throughput screening
|
|
JP2002522063A
(ja)
|
1998-08-17 |
2002-07-23 |
アブジェニックス インコーポレイテッド |
増加した血清半減期を有する改変された分子の生成
|
|
US20030215458A1
(en)
|
1998-09-30 |
2003-11-20 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
WO2000034337A1
(en)
|
1998-12-10 |
2000-06-15 |
Tsukuba Research Laboratory, Toagosei Co., Ltd. |
Humanized monoclonal antibodies against vascular endothelial cell growth factor
|
|
ES2706547T3
(es)
|
1998-12-23 |
2019-03-29 |
Pfizer |
Anticuerpos monoclonales humanos para CTLA-4
|
|
US8003772B2
(en)
|
1999-01-14 |
2011-08-23 |
Martek Biosciences Corporation |
Chimeric PUFA polyketide synthase systems and uses thereof
|
|
HUP0104865A3
(en)
|
1999-01-15 |
2004-07-28 |
Genentech Inc |
Polypeptide variants with altered effector function
|
|
AU4025300A
(en)
|
1999-03-24 |
2000-10-09 |
Packard Bioscience Company |
Continuous porous matrix arrays
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
BR0009323A
(pt)
|
1999-03-25 |
2002-01-08 |
Knoll Gmbh |
Anticorpos humanos que ligam a il-12 humana e métodos para a produção
|
|
EP2275540B1
(en)
|
1999-04-09 |
2016-03-23 |
Kyowa Hakko Kirin Co., Ltd. |
Method for controlling the activity of immunologically functional molecule
|
|
CN1119415C
(zh)
|
1999-06-04 |
2003-08-27 |
长春迈灵生物工程有限公司 |
抗ca125双功能基因工程抗体的克隆与表达
|
|
US7087411B2
(en)
|
1999-06-08 |
2006-08-08 |
Regeneron Pharmaceuticals, Inc. |
Fusion protein capable of binding VEGF
|
|
US6531580B1
(en)
|
1999-06-24 |
2003-03-11 |
Ixsys, Inc. |
Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same
|
|
EP2977063A1
(en)
|
1999-06-25 |
2016-01-27 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
AU1456101A
(en)
|
1999-11-03 |
2001-05-14 |
Maxygen, Inc. |
Antibody diversity generation
|
|
SK12942002A3
(sk)
|
2000-02-10 |
2003-05-02 |
Abbott Laboratories |
Protilátky viažuce ľudský interleukín-18, spôsoby ich výroby a použitia
|
|
HUP0300024A2
(en)
|
2000-02-24 |
2003-05-28 |
Genentech Inc |
Caspase activated prodrugs therapy
|
|
YU63302A
(sh)
|
2000-02-25 |
2005-09-19 |
The Government Of The Un.Stat. |
Anti-egfrv iii scfvs sa pojačanom citotoksičnošću i povećanim prinosom, imunotoksini na bazi istog i metodi za upotrebu na bazi istog
|
|
EP1266014A2
(en)
|
2000-03-24 |
2002-12-18 |
Peter Kufer |
Multifunctional polypeptides comprising a binding site to an epitope of the nkg2d receptor complex
|
|
PT2857516T
(pt)
|
2000-04-11 |
2017-08-28 |
Genentech Inc |
Anticorpos multivalentes e utilizações dos mesmos
|
|
EP1278778A2
(en)
|
2000-05-03 |
2003-01-29 |
Amgen Inc., |
Modified peptides, comprising an fc domain, as therapeutic agents
|
|
CA2409361A1
(en)
|
2000-05-19 |
2001-11-22 |
Scancell Limited |
Humanised antibodies to the epidermal growth factor receptor
|
|
US7449308B2
(en)
|
2000-06-28 |
2008-11-11 |
Glycofi, Inc. |
Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
|
|
US7029872B2
(en)
|
2000-06-28 |
2006-04-18 |
Glycofi, Inc |
Methods for producing modified glycoproteins
|
|
PE20020132A1
(es)
|
2000-06-29 |
2002-03-04 |
Abbott Lab |
Anticuerpos de especificidad doble y metodos para la elaboracion y el uso de los mismos
|
|
AU2001270609A1
(en)
|
2000-06-30 |
2002-01-14 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Heterodimeric fusion proteins
|
|
US20090081234A1
(en)
|
2000-08-07 |
2009-03-26 |
George Heavner |
Anti-tnf antibodies, compositions, methods and uses for treatment of depression and related conditions
|
|
GB0020685D0
(en)
*
|
2000-08-22 |
2000-10-11 |
Novartis Ag |
Organic compounds
|
|
US20030157643A1
(en)
|
2000-08-24 |
2003-08-21 |
Almond Brian D |
Synthetic nucleic acids from aquatic species
|
|
MXPA00009407A
(es)
|
2000-09-26 |
2004-12-08 |
Mexicano Inst Petrol |
Procedimiento para la preparacion de un catalizador monometalico de tipo zeolitico para la obtencion de gasolinas de alto octando mediante reformacion de naftas.
|
|
US6699473B2
(en)
|
2000-10-13 |
2004-03-02 |
Uab Research Foundation |
Human anti-epidermal growth factor receptor single-chain antibodies
|
|
US7446179B2
(en)
|
2000-11-07 |
2008-11-04 |
City Of Hope |
CD19-specific chimeric T cell receptor
|
|
US7601692B2
(en)
|
2000-11-28 |
2009-10-13 |
Compugen Ltd. |
MCP-1 splice variants and methods of using same
|
|
PE20020574A1
(es)
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
US6818392B2
(en)
|
2000-12-06 |
2004-11-16 |
Abbott Laboratories |
Monoclonal antibodies to human immunodeficiency virus and uses thereof
|
|
EP1345968A2
(en)
|
2000-12-28 |
2003-09-24 |
Altus Biologics Inc. |
Crystals of whole antibodies and fragments thereof and methods for making and using them
|
|
US7667004B2
(en)
|
2001-04-17 |
2010-02-23 |
Abmaxis, Inc. |
Humanized antibodies against vascular endothelial growth factor
|
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
|
WO2002097048A2
(en)
|
2001-05-30 |
2002-12-05 |
Centocor, Inc. |
ANTI-p40 IMMUNOGLOBULIN DERIVED PROTEINS, COMPOSITIONS, METHODS AND USES
|
|
KR20100132559A
(ko)
|
2001-05-30 |
2010-12-17 |
제넨테크, 인크. |
다양한 질환의 치료에 유용한 항-엔지에프 항체
|
|
KR100945108B1
(ko)
|
2001-06-13 |
2010-03-02 |
젠맵 에이/에스 |
표피 성장 인자 수용체 (ｅｇｆｒ)에 대한 인간모노클로날 항체
|
|
ATE524495T1
(de)
|
2001-07-31 |
2011-09-15 |
Ono Pharmaceutical Co |
Pd-1-spezifische substanz
|
|
WO2003016466A2
(en)
|
2001-08-17 |
2003-02-27 |
Eli Lilly And Company |
ANTI-Aβ ANTIBODIES
|
|
US7247304B2
(en)
|
2001-08-23 |
2007-07-24 |
Genmab A/S |
Methods of treating using anti-IL-15 antibodies
|
|
RU2305111C2
(ru)
|
2001-09-25 |
2007-08-27 |
Джуридикэл Фаундейшн Дзе Чемо-Серо-Терапьютик Рисерч Инститьют |
Рекомбинантное антитело против остеопонтина и его применение
|
|
US20030186374A1
(en)
|
2001-10-01 |
2003-10-02 |
Hufton Simon E. |
Multi-chain eukaryotic display vectors and uses thereof
|
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
|
PL213948B1
(pl)
|
2001-10-25 |
2013-05-31 |
Genentech Inc |
Kompozycje zawierajace glikoproteine, czasteczka kwasu nukleinowego kodujaca te glikoproteine, komórka gospodarza, sposób wytwarzania glikoproteiny, kompozycja do zastosowania do leczenia, zastosowanie kompozycji i zestaw zawierajacy kompozycje
|
|
WO2003039486A2
(en)
|
2001-11-09 |
2003-05-15 |
Idec Pharmaceuticals Corporation |
Anti-cd80 antibody having adcc activity for adcc mediated killing of b cell lymphoma cells alone or in combination with other therapies
|
|
DE10156482A1
(de)
|
2001-11-12 |
2003-05-28 |
Gundram Jung |
Bispezifisches Antikörper-Molekül
|
|
BRPI0214168B8
(pt)
|
2001-11-14 |
2021-05-25 |
Centocor Inc |
anticorpos anti-il-6, moléculas de ácido nucleico codificando os mesmos, vetores compreendendo as referidas moléculas, composições e formulações compreendendo os referidos anticorpos, bem como métodos de produção dos mesmos
|
|
AU2002351353A1
(en)
|
2001-12-19 |
2003-09-02 |
Genentech, Inc. |
Stabilizing polypeptides which have been exposed to urea
|
|
EP1472275B1
(en)
|
2002-02-05 |
2008-12-17 |
Genentech, Inc. |
Protein purification
|
|
MXPA04007583A
(es)
|
2002-02-11 |
2005-04-25 |
Genentech Inc |
Variantes de anticuerpo con tasas mas rapidas de asociacion a antigeno.
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
US7419821B2
(en)
|
2002-03-05 |
2008-09-02 |
I-Stat Corporation |
Apparatus and methods for analyte measurement and immunoassay
|
|
EP2270049A3
(en)
|
2002-04-12 |
2011-03-09 |
Medimmune, Inc. |
Recombinant anti-interleukin-9-antibody
|
|
US20040018573A1
(en)
|
2002-04-18 |
2004-01-29 |
Power Scott D |
Production of functional antibodies in filamentous fungi
|
|
US20030206898A1
(en)
|
2002-04-26 |
2003-11-06 |
Steven Fischkoff |
Use of anti-TNFalpha antibodies and another drug
|
|
SI1501369T1
(sl)
|
2002-04-26 |
2015-10-30 |
Genentech, Inc. |
Neafinitetno čiščenje proteinov
|
|
EP1505075B1
(en)
|
2002-04-30 |
2009-10-07 |
Kyowa Hakko Kirin Co., Ltd. |
Antibody to human insulin-like growth factor
|
|
US7714189B2
(en)
|
2002-05-03 |
2010-05-11 |
Monsanto Technology Llc |
High tryptophan maize
|
|
MXPA04011624A
(es)
|
2002-05-24 |
2005-03-07 |
Schering Corp |
Anticuerpo neutralizante humano anti-igfr.
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
NZ537277A
(en)
|
2002-07-18 |
2008-04-30 |
Crucell Holland Bv |
Recombinant production of mixtures of antibodies
|
|
US20040018577A1
(en)
|
2002-07-29 |
2004-01-29 |
Emerson Campbell John Lewis |
Multiple hybrid immunoassay
|
|
US20040033228A1
(en)
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
|
EP1542724A4
(en)
|
2002-08-19 |
2005-10-19 |
Abgenix Inc |
ANTIBODIES AGAINST THE MONOCYTE 1 CHIMIOATTRACTIVE PROTEIN (MCP-1) AND USES THEREOF
|
|
PT1543038T
(pt)
|
2002-09-11 |
2017-07-07 |
Genentech Inc |
Purificação de proteína
|
|
CA2721200A1
(en)
|
2002-11-22 |
2004-06-10 |
Eisai R&D Management Co., Ltd. |
Methods of screening for compounds that inhibit the biosynthesis of gpi in malaria parasites
|
|
JP4754219B2
(ja)
|
2002-12-02 |
2011-08-24 |
アムジエン・フレモント・インコーポレイテツド |
腫瘍壊死因子を対象とする抗体、およびそれらの使用
|
|
HUE035898T2
(en)
|
2002-12-16 |
2018-05-28 |
Genentech Inc |
Immunoglobulin variants and their applications
|
|
DK1575517T3
(da)
|
2002-12-24 |
2012-05-14 |
Rinat Neuroscience Corp |
Anti-ngf-antistoffer og fremgangsmåder til anvendelse af samme
|
|
WO2004065417A2
(en)
|
2003-01-23 |
2004-08-05 |
Genentech, Inc. |
Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture
|
|
EP2330213A1
(en)
|
2003-03-05 |
2011-06-08 |
Halozyme, Inc. |
Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
EP2365001A3
(en)
|
2003-05-01 |
2012-03-28 |
Imclone LLC |
Fully human antibodies directed against the human insulin-like growth factor-1 receptor
|
|
EP1633382A4
(en)
|
2003-05-14 |
2009-08-05 |
Dow Corning |
REPEAT SEQUENCE PROTEIN-POLYMER-ACTIVE CONJUGATE, METHOD AND USES
|
|
US20070104722A1
(en)
|
2003-05-15 |
2007-05-10 |
Iogenetics |
Targeted biocides
|
|
AU2004242846A1
(en)
|
2003-05-31 |
2004-12-09 |
Micromet Ag |
Pharmaceutical compositions comprising bispecific anti-CD3, anti-CD19 antibody constructs for the treatment of B-cell related disorders
|
|
EA015363B1
(ru)
|
2003-07-18 |
2011-06-30 |
Эмджен Инк. |
Агенты, специфически связывающие фактор роста гепатоцитов, и их применение
|
|
JP4599355B2
(ja)
|
2003-07-28 |
2010-12-15 |
ジェネンテック， インコーポレイテッド |
プロテインａアフィニティークロマトグラフィーの間のプロテインａの浸出の低減
|
|
US20050026881A1
(en)
|
2003-07-31 |
2005-02-03 |
Robinson Cynthia B. |
Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anti-IgE antibody for treatment of asthma or chronic obstructive pulmonary disease
|
|
US20050106667A1
(en)
|
2003-08-01 |
2005-05-19 |
Genentech, Inc |
Binding polypeptides with restricted diversity sequences
|
|
WO2005044853A2
(en)
|
2003-11-01 |
2005-05-19 |
Genentech, Inc. |
Anti-vegf antibodies
|
|
US7662928B2
(en)
|
2003-08-08 |
2010-02-16 |
The Research Foundation Of State University Of New York |
Anti-FcRn antibodies for treatment of auto/allo immune conditions
|
|
AU2004266159A1
(en)
|
2003-08-22 |
2005-03-03 |
Biogen Idec Ma Inc. |
Improved antibodies having altered effector function and methods for making the same
|
|
US20050042664A1
(en)
|
2003-08-22 |
2005-02-24 |
Medimmune, Inc. |
Humanization of antibodies
|
|
US7682833B2
(en)
|
2003-09-10 |
2010-03-23 |
Abbott Point Of Care Inc. |
Immunoassay device with improved sample closure
|
|
US7723099B2
(en)
|
2003-09-10 |
2010-05-25 |
Abbott Point Of Care Inc. |
Immunoassay device with immuno-reference electrode
|
|
US20060134105A1
(en)
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
|
JP2007526022A
(ja)
|
2003-10-24 |
2007-09-13 |
メドトロニック・インコーポレーテッド |
炎症誘発性媒介物質の産生を減弱することによって神経性障害を処置する技法
|
|
US7968684B2
(en)
|
2003-11-12 |
2011-06-28 |
Abbott Laboratories |
IL-18 binding proteins
|
|
US7754500B2
(en)
|
2003-11-21 |
2010-07-13 |
Anp Technologies, Inc. |
Asymmetrically branched polymer conjugates and microarray assays
|
|
JP2007512846A
(ja)
|
2003-12-04 |
2007-05-24 |
ゼンコー・インコーポレイテッド |
増加した宿主ストリング含有量を有する変異体タンパク質の生成方法およびその組成物
|
|
JP2007517504A
(ja)
|
2003-12-09 |
2007-07-05 |
ベントリア バイオサイエンス |
融合担体として種子貯蔵蛋白を利用する植物種子中の融合ポリペプチドの高水準発現
|
|
US7235641B2
(en)
|
2003-12-22 |
2007-06-26 |
Micromet Ag |
Bispecific antibodies
|
|
ITRM20030601A1
(it)
|
2003-12-24 |
2005-06-25 |
Lay Line Genomics Spa |
Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti.
|
|
US7297541B2
(en)
|
2004-01-26 |
2007-11-20 |
Monsanto Technology Llc |
Genes encoding 4-hydroxyphenylpyruvate dioxygenase (HPPD) enzymes for plant metabolic engineering
|
|
US7794713B2
(en)
|
2004-04-07 |
2010-09-14 |
Lpath, Inc. |
Compositions and methods for the treatment and prevention of hyperproliferative diseases
|
|
AU2005249360B2
(en)
|
2004-04-12 |
2011-07-21 |
Medimmune, Llc |
Anti-IL-9 antibody formulations and uses thereof
|
|
JP2007535317A
(ja)
|
2004-04-15 |
2007-12-06 |
グライコフィ， インコーポレイテッド |
下等真核生物におけるガラクトシル化された糖タンパク質の産生
|
|
EP1740616B1
(en)
|
2004-04-30 |
2011-12-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-tfr antibody.
|
|
EP1751288A2
(en)
|
2004-05-19 |
2007-02-14 |
Agrivida, Inc. |
Transgenic plants expressing intein modified proteins and associated processes for bio-pharmaceutical production
|
|
US7150969B2
(en)
|
2004-06-04 |
2006-12-19 |
Rosetta Inpharmatics Llc |
Alternatively spliced isoform of acetyl-CoA carboxylase 2 (ACC2)
|
|
EP1786918A4
(en)
|
2004-07-17 |
2009-02-11 |
Imclone Systems Inc |
NEW BISPECIFIC ANTIBODY TETRAVALENT
|
|
ES2414460T3
(es)
|
2004-08-04 |
2013-07-19 |
Amgen Inc. |
Anticuerpos para Dkk-1
|
|
ME01803B
(me)
|
2004-08-05 |
2010-12-31 |
Genentech Inc |
Humanizovani anti-cmet antagonisti
|
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
|
CA2577133A1
(en)
|
2004-08-19 |
2006-03-23 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
GB0419424D0
(en)
|
2004-09-02 |
2004-10-06 |
Viragen Scotland Ltd |
Transgene optimisation
|
|
ES2377979T3
(es)
|
2004-09-03 |
2012-04-03 |
Genentech, Inc. |
Antagonistas anti-beta7 humanizados y utilizaciones para los mismos
|
|
US20060067931A1
(en)
*
|
2004-09-25 |
2006-03-30 |
Hazel Lum |
Receptor for lysophosphatidylcholine in vascular endothelial cells and use thereof
|
|
WO2006037604A1
(en)
|
2004-10-01 |
2006-04-13 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Novel antibodies directed to the mammalian eag1 ion channel protein
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
WO2006047350A2
(en)
|
2004-10-21 |
2006-05-04 |
Xencor, Inc. |
IgG IMMUNOGLOBULIN VARIANTS WITH OPTIMIZED EFFECTOR FUNCTION
|
|
EP1805320B1
(en)
|
2004-10-22 |
2014-09-03 |
Amgen Inc. |
Methods for refolding of recombinant antibodies
|
|
US20060253100A1
(en)
|
2004-10-22 |
2006-11-09 |
Medtronic, Inc. |
Systems and Methods to Treat Pain Locally
|
|
US7423128B2
(en)
|
2004-11-03 |
2008-09-09 |
Amgen Fremont Inc. |
Anti-properdin antibodies, and methods for making and using same
|
|
US20070135620A1
(en)
|
2004-11-12 |
2007-06-14 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US20060257396A1
(en)
|
2004-12-15 |
2006-11-16 |
Jacobsen Jack S |
Abeta antibodies for use in improving cognition
|
|
ZA200705695B
(en)
|
2004-12-21 |
2009-02-25 |
Astrazeneca Ab |
Antibodies directed to angiopoietin-2 and uses thereof
|
|
WO2006118617A2
(en)
|
2004-12-23 |
2006-11-09 |
Chlorogen, Inc. |
EXPRESSING TGF-β PROTEINS IN PLANT PLASTIDS
|
|
EP2361933A3
(en)
|
2005-01-26 |
2012-05-02 |
Amgen Fremont Inc. |
Antibodies against interleukin-1 beta
|
|
US20060263357A1
(en)
|
2005-05-05 |
2006-11-23 |
Tedder Thomas F |
Anti-CD19 antibody therapy for autoimmune disease
|
|
PT1853718E
(pt)
|
2005-02-15 |
2015-11-12 |
Univ Duke |
Anticorpos anti-cd19 e usos em oncologia
|
|
AU2006216291B2
(en)
|
2005-02-27 |
2011-01-27 |
Institute For Antibodies Co., Ltd. |
Anti-IgSF4 antibody and utilization of the same
|
|
NZ561763A
(en)
|
2005-03-24 |
2009-02-28 |
Thrombogenics Nv |
Novel anti PLGF antibody
|
|
CA2604032C
(en)
|
2005-04-06 |
2017-08-22 |
Ibc Pharmaceuticals, Inc. |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
|
|
TW200724548A
(en)
|
2005-04-25 |
2007-07-01 |
Pfizer |
Antibodies to myostatin
|
|
US7592429B2
(en)
|
2005-05-03 |
2009-09-22 |
Ucb Sa |
Sclerostin-binding antibody
|
|
WO2006130374A2
(en)
|
2005-05-27 |
2006-12-07 |
Biogen Idec Ma Inc. |
Tweak binding antibodies
|
|
ITRM20050290A1
(it)
|
2005-06-07 |
2006-12-08 |
Lay Line Genomics Spa |
Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
|
|
CA2612648A1
(en)
|
2005-06-24 |
2006-12-28 |
Novozymes A/S |
Lipases for pharmaceutical use
|
|
CA2613818C
(en)
|
2005-06-30 |
2013-08-27 |
Centocor, Inc. |
Anti-il-23 antibodies, compositions, methods and uses
|
|
WO2007032837A2
(en)
|
2005-08-11 |
2007-03-22 |
The J. Craig Venter Institute |
Method for in vitro recombination
|
|
KR20140053410A
(ko)
*
|
2005-08-19 |
2014-05-07 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
US7612181B2
(en)
*
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
US20090215992A1
(en)
|
2005-08-19 |
2009-08-27 |
Chengbin Wu |
Dual variable domain immunoglobulin and uses thereof
|
|
US20070041905A1
(en)
|
2005-08-19 |
2007-02-22 |
Hoffman Rebecca S |
Method of treating depression using a TNF-alpha antibody
|
|
AU2006290433B2
(en)
|
2005-08-26 |
2012-06-07 |
Roche Glycart Ag |
Modified antigen binding molecules with altered cell signaling activity
|
|
US7906116B2
(en)
|
2005-09-01 |
2011-03-15 |
Parkash Gill |
Methods for using and identifying modulators of Delta-like 4
|
|
CA2623648C
(en)
|
2005-09-21 |
2018-05-22 |
The Regents Of The University Of California |
Systems, compositions, and methods for local imaging and treatment of pain
|
|
WO2007038392A2
(en)
|
2005-09-23 |
2007-04-05 |
Walter Reed Army Institute Of Research (Wrair) |
Antibodies with simultaneous subsite specificities to protein and lipid epitopes
|
|
US8236308B2
(en)
|
2005-10-11 |
2012-08-07 |
Micromet Ag |
Composition comprising cross-species-specific antibodies and uses thereof
|
|
EP1945771A1
(en)
|
2005-10-28 |
2008-07-23 |
Novo Nordisk A/S |
Fusion proteins that bind effector lymphocytes and target cells
|
|
UA96139C2
(uk)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)
|
|
AR056806A1
(es)
|
2005-11-14 |
2007-10-24 |
Amgen Inc |
Moleculas quimericas de anticuerpo rankl- pth/ pthrp
|
|
PL1948798T3
(pl)
|
2005-11-18 |
2015-12-31 |
Glenmark Pharmaceuticals Sa |
Przeciwciała przeciwko integrynie alfa2 i ich zastosowania
|
|
WO2007062037A2
(en)
|
2005-11-21 |
2007-05-31 |
Laboratoires Serono Sa |
Compositions and methods of producing hybrid antigen binding molecules and uses thereof
|
|
RU2442793C2
(ru)
|
2005-11-30 |
2012-02-20 |
Эбботт Лэборетриз |
АНТИТЕЛА ПРОТИВ ГЛОБУЛОМЕРА Аβ, ИХ АНТИГЕНСВЯЗЫВАЮЩИЕ ЧАСТИ, СООТВЕТСТВУЮЩИЕ ГИБРИДОМЫ, НУКЛЕИНОВЫЕ КИСЛОТЫ, ВЕКТОРЫ, КЛЕТКИ-ХОЗЯЕВА, СПОСОБЫ ПОЛУЧЕНИЯ УКАЗАННЫХ АНТИТЕЛ, КОМПОЗИЦИИ, СОДЕРЖАЩИЕ УКАЗАННЫЕ АНТИТЕЛА, ПРИМЕНЕНИЯ УКАЗАННЫХ АНТИТЕЛ И СПОСОБЫ ИСПОЛЬЗОВАНИЯ УКАЗАННЫХ АНТИТЕЛ
|
|
PL1979001T3
(pl)
|
2005-12-13 |
2012-09-28 |
Medimmune Ltd |
Białka wiążące specyficzne dla insulinopodobnych czynników wzrostu i ich zastosowania
|
|
CN101415415A
(zh)
|
2006-01-23 |
2009-04-22 |
约瑟夫·P·埃里科 |
定向药物开发的方法和组合物
|
|
US8377691B2
(en)
|
2006-01-26 |
2013-02-19 |
Integral Molecular, Inc. |
Lipoparticles comprising ion channels, methods of making and using the same
|
|
CA2637166A1
(en)
*
|
2006-01-31 |
2007-10-18 |
Novartis Ag |
Il-17 antagonistic antibodies for treating cancer
|
|
US20070207171A1
(en)
|
2006-03-01 |
2007-09-06 |
Cerus Corporation |
Engineered listeria and methods of use thereof
|
|
EA015992B1
(ru)
|
2006-03-17 |
2012-01-30 |
Байоджен Айдек Эмэй Инк. |
Стабилизированное антитело и многовалентная антигенсвязывающая молекула на его основе, способы получения и использования вышеназванного стабилизированного антитела
|
|
MX2008011933A
(es)
|
2006-03-21 |
2008-12-18 |
Wyeth Corp |
Metodos y composiciones para antagonismo de rage.
|
|
DK1999154T3
(da)
|
2006-03-24 |
2012-12-03 |
Merck Patent Gmbh |
Fremstillede heterodimere proteindomæner
|
|
JP2009532027A
(ja)
|
2006-03-28 |
2009-09-10 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
抗ｉｇｆ−１ｒ抗体およびその使用
|
|
US20070232556A1
(en)
|
2006-03-31 |
2007-10-04 |
Montine Thomas J |
Methods and compositions for the treatment of neurological diseases and disorders
|
|
WO2007120651A2
(en)
|
2006-04-10 |
2007-10-25 |
Abbott Biotechnology Ltd. |
Uses and compositions for treatment of juvenile rheumatoid arthritis
|
|
KR20110079922A
(ko)
|
2006-04-14 |
2011-07-11 |
노파르티스 아게 |
안과 장애 치료를 위한 ｉｌ－1 항체의 용도
|
|
US8173860B2
(en)
|
2006-04-21 |
2012-05-08 |
Gtc Biotherapeutics, Inc. |
Non-human transgenic mammal expressing a human FcRn on its mammary gland cells and expressing a transgenic protein-human Fc-domain fusion
|
|
SMP200800064B
(it)
|
2006-04-21 |
2009-11-06 |
Novartis Ag |
Composizioni farmaceutiche di anticorpi anti-cd40 antagonista
|
|
US20070254338A1
(en)
|
2006-04-24 |
2007-11-01 |
Amgen Inc. |
Method for making recombinant protein using complementation dependent DHFR mutants
|
|
US20080118978A1
(en)
|
2006-04-28 |
2008-05-22 |
Takashi Sato |
Anti-tumor agent
|
|
CN101058609B
(zh)
|
2006-05-26 |
2011-04-13 |
神州细胞工程有限公司 |
人源抗体及其表达
|
|
MX2008015138A
(es)
|
2006-06-02 |
2009-01-28 |
Aveo Pharmaceuticals Inc |
Proteinas de union al factor de crecimiento de hepatocitos (fch).
|
|
JP2009539870A
(ja)
|
2006-06-06 |
2009-11-19 |
ジェネンテック・インコーポレーテッド |
血管発生の調節ための組成物および方法
|
|
AU2007319672B2
(en)
|
2006-06-06 |
2011-06-30 |
Genentech, Inc. |
Anti-DLL4 antibodies and methods using same
|
|
CN1884517B
(zh)
|
2006-06-08 |
2010-06-30 |
武汉禾元生物科技有限公司 |
利用谷物非储藏蛋白为融合载体在胚乳表达多肽的方法及应用
|
|
WO2007147901A1
(en)
|
2006-06-22 |
2007-12-27 |
Novo Nordisk A/S |
Production of bispecific antibodies
|
|
WO2008005469A2
(en)
|
2006-06-30 |
2008-01-10 |
Schering Corporation |
Igfbp2 biomarker
|
|
US20080081379A1
(en)
|
2006-07-13 |
2008-04-03 |
Sigler Gerald F |
Homogeneous double receptor agglutination assay for immunosuppressant drugs
|
|
RU2498999C2
(ru)
|
2006-07-14 |
2013-11-20 |
Ац Иммуне Са |
Гуманизированное антитело к амилоиду бета
|
|
US7592156B2
(en)
|
2006-07-20 |
2009-09-22 |
Wyeth |
Synthetic dog/human chimeric C-C chemokine receptor 2B
|
|
US7883855B2
(en)
|
2006-07-21 |
2011-02-08 |
Abbott Laboratories |
Immunosuppressant drug extraction reagent for immunoassays
|
|
MX2009001573A
(es)
|
2006-08-11 |
2009-02-19 |
Monsanto Technology Llc |
Produccion de maiz alto en triptofano mediante la expresion dirigida al cloroplasto de la antranilato sintasa.
|
|
RS53263B
(sr)
|
2006-08-14 |
2014-08-29 |
Xencor Inc. |
Optimizovana antitela usmerena na cd19
|
|
HUE052220T2
(hu)
|
2006-09-08 |
2021-04-28 |
Abbvie Bahamas Ltd |
Interleukin-13 kötõfehérjék
|
|
US20080075690A1
(en)
|
2006-09-22 |
2008-03-27 |
Mark Douglas Howell |
Method for enhancing immune responses in mammals
|
|
HRP20160082T1
(hr)
|
2006-09-29 |
2016-02-26 |
Oncomed Pharmaceuticals, Inc. |
Sastavi i postupci za dijagnosticiranje i lijeäśenje raka
|
|
US20080102475A1
(en)
|
2006-10-13 |
2008-05-01 |
Zhengyan Kan |
Alternatively spliced isoform of phosphodiesterase 4B (PDE4B)
|
|
CN106084055A
(zh)
|
2006-11-02 |
2016-11-09 |
健泰科生物技术公司 |
人源化的抗‑d因子抗体
|
|
EP2120996A2
(en)
|
2006-12-20 |
2009-11-25 |
Vasgene Therapeutics, Inc. |
Methods for using and identifying modulators of delta-like 4
|
|
WO2008100995A1
(en)
|
2007-02-14 |
2008-08-21 |
Vaccinex, Inc. |
Humanized anti-cd100 antibodies
|
|
NZ579644A
(en)
|
2007-02-16 |
2012-05-25 |
Merrimack Pharmaceuticals Inc |
Antibodies against erbb3 and uses thereof
|
|
BRPI0809042B1
(pt)
|
2007-03-22 |
2021-08-31 |
Biogen Ma Inc. |
Proteína de ligação a cd154 isolada, seu uso, e composição
|
|
US7906293B2
(en)
|
2007-04-09 |
2011-03-15 |
Abbott Laboratories |
Acridinium phenyl esters useful in the analysis of biological
|
|
US20090068195A1
(en)
|
2007-04-23 |
2009-03-12 |
Wyeth |
Methods and compositions for treating and monitoring treatment of il-13-associated disorders
|
|
GB0708002D0
(en)
|
2007-04-25 |
2007-06-06 |
Univ Sheffield |
Antibodies
|
|
EP1997832A1
(en)
|
2007-05-29 |
2008-12-03 |
Ganymed Pharmaceuticals AG |
Monoclonal antibodies against Claudin-18 for treatment of cancer
|
|
DK2164992T3
(en)
|
2007-05-30 |
2016-08-15 |
Lpath Inc |
COMPOSITIONS AND METHODS FOR BONDING OF LYTHOPHOSPHATIC ACID
|
|
US8227201B2
(en)
|
2007-06-27 |
2012-07-24 |
Board Of Trustees Of The Leland Stanford Junior University |
BETA2-microglobulin and C reactive protein (CRP) as biomarkers for peripheral artery disease
|
|
CN101952312A
(zh)
|
2007-07-31 |
2011-01-19 |
米迪缪尼有限公司 |
多特异性表位结合蛋白及其应用
|
|
MX2010001488A
(es)
|
2007-08-08 |
2010-03-01 |
Abbott Lab |
Composiciones y metodos para cristalizar anticuerpos.
|
|
CA2696263C
(en)
|
2007-08-15 |
2017-06-13 |
Bing Liu |
Monospecific and multispecific antibodies and method of use
|
|
EP2225268B1
(en)
|
2007-10-19 |
2012-08-29 |
Abbott Laboratories |
Immunoassays and kits for the detection of ngal
|
|
JP5737944B2
(ja)
|
2007-12-17 |
2015-06-17 |
ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ |
間質性膀胱炎の治療
|
|
EP3663318A1
(en)
|
2008-01-07 |
2020-06-10 |
Amgen Inc. |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
|
ES2579231T3
(es)
|
2008-01-15 |
2016-08-08 |
Abbvie Inc |
Vectores de expresión de mamíferos mejorados y usos de los mismos
|
|
US7605603B1
(en)
*
|
2008-02-29 |
2009-10-20 |
Altera Corporation |
User-accessible freeze-logic for dynamic power reduction and associated methods
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
JP5470817B2
(ja)
|
2008-03-10 |
2014-04-16 |
日産自動車株式会社 |
電池用電極およびこれを用いた電池、並びにその製造方法
|
|
EP2282769A4
(en)
*
|
2008-04-29 |
2012-04-25 |
Abbott Lab |
DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES
|
|
US20100260668A1
(en)
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
|
CN102089430B
(zh)
|
2008-05-09 |
2015-02-04 |
Abbvie公司 |
针对渐进性糖化终极产物受体(rage)的抗体及其用途
|
|
KR20110016959A
(ko)
|
2008-06-03 |
2011-02-18 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
US8741287B2
(en)
|
2008-06-18 |
2014-06-03 |
Abbott Laboratories |
PlGF-1 assay and kits and components thereof
|
|
US8822645B2
(en)
*
|
2008-07-08 |
2014-09-02 |
Abbvie Inc. |
Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
|
|
KR20110040886A
(ko)
|
2008-07-08 |
2011-04-20 |
아보트 러보러터리즈 |
프로스타글란딘 ｅ2 결합 단백질 및 이의 용도
|
|
US9273136B2
(en)
|
2008-08-04 |
2016-03-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Fully human anti-human NKG2D monoclonal antibodies
|
|
MX2011003381A
(es)
|
2008-09-30 |
2011-04-21 |
Abbott Lab |
Metodo mejorado para despliegue de arn.
|
|
CA2743841C
(en)
|
2008-11-13 |
2020-09-01 |
Eastern Virginia Medical School |
Activation and aggregation of human platelets and formation of platelet gels by nanosecond pulsed electric fields
|
|
SG171812A1
(en)
|
2008-12-04 |
2011-07-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
NZ594514A
(en)
*
|
2009-03-05 |
2013-06-28 |
Abbott Lab |
Interleukin-17 BINDING PROTEINS
|
|
BRPI1012195A2
(en)
|
2009-05-01 |
2018-04-24 |
Abbott Laboratories |
double variable domain immunoglobulins and their uses
|
|
WO2010127284A2
(en)
|
2009-05-01 |
2010-11-04 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
|
TW201109438A
(en)
|
2009-07-29 |
2011-03-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
CA2771575A1
(en)
|
2009-08-29 |
2011-03-03 |
Abbott Laboratories |
Therapeutic dll4 binding proteins
|
|
MX2012002651A
(es)
|
2009-09-01 |
2012-05-22 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
|
UY32920A
(es)
|
2009-10-02 |
2011-04-29 |
Boehringer Ingelheim Int |
Moleculas de unión biespecíficas para la terapia anti-angiogénesis
|
|
AR078651A1
(es)
|
2009-10-15 |
2011-11-23 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
AU2010306681A1
(en)
|
2009-10-15 |
2012-04-19 |
Abbvie Inc. |
IL-1 binding proteins
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
WO2011109298A2
(en)
|
2010-03-02 |
2011-09-09 |
Abbott Laboratories |
Therapeutic dll4 binding proteins
|
|
TWI500427B
(zh)
|
2010-05-14 |
2015-09-21 |
Abbvie Inc |
Ｉｌ－１結合蛋白
|
|
BR112012032778A2
(pt)
|
2010-06-24 |
2019-09-24 |
Abbvie Inc |
"proteínas multiespecíficas e multivalentes"
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
KR20130100118A
(ko)
|
2010-08-03 |
2013-09-09 |
아비에 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
US9046513B2
(en)
|
2010-08-26 |
2015-06-02 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
JP2014500712A
(ja)
|
2010-11-02 |
2014-01-16 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリンおよびその使用
|
|
UY33707A
(es)
|
2010-11-04 |
2012-05-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
AR089529A1
(es)
|
2011-12-30 |
2014-08-27 |
Abbvie Inc |
Proteinas de union especificas duales dirigidas contra il-13 y/o il-17
|
|
WO2013101972A2
(en)
|
2011-12-30 |
2013-07-04 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
TW201333039A
(zh)
|
2011-12-30 |
2013-08-16 |
Abbvie Inc |
雙可變域免疫球蛋白及其用途
|
|
PE20151179A1
(es)
|
2012-11-01 |
2015-09-12 |
Abbvie Inc |
Inmunoglobulinas de dominio variable dual anti-vegf/dll4 y usos de las mismas
|
|
US20140213772A1
(en)
|
2012-12-28 |
2014-07-31 |
Abbvie, Inc. |
Cross-over dual variable domain immunoglobulin constructs
|
|
JP6136279B2
(ja)
|
2013-01-15 |
2017-05-31 |
株式会社ジェイテクト |
転がり軸受装置
|
|
AU2014227732A1
(en)
|
2013-03-15 |
2015-09-17 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-1 beta and IL-17
|
|
CA2904407A1
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Inc. |
Dual specific binding proteins directed against tnf.alpha.
|
|
TWI503850B
(zh)
|
2013-03-22 |
2015-10-11 |
Polytronics Technology Corp |
過電流保護元件
|
|
TWI510996B
(zh)
|
2013-10-03 |
2015-12-01 |
Acer Inc |
控制觸控面板的方法以及使用該方法的可攜式電腦
|
|
US9816280B1
(en)
|
2016-11-02 |
2017-11-14 |
Matthew Reitnauer |
Portable floor
|