ITRM20050290A1 - Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato. - Google Patents
Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.Info
- Publication number
- ITRM20050290A1 ITRM20050290A1 IT000290A ITRM20050290A ITRM20050290A1 IT RM20050290 A1 ITRM20050290 A1 IT RM20050290A1 IT 000290 A IT000290 A IT 000290A IT RM20050290 A ITRM20050290 A IT RM20050290A IT RM20050290 A1 ITRM20050290 A1 IT RM20050290A1
- Authority
- IT
- Italy
- Prior art keywords
- ngf
- analgesics
- inhibit
- molecules
- bond
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000290A ITRM20050290A1 (it) | 2005-06-07 | 2005-06-07 | Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato. |
CN2006800288760A CN101277718B (zh) | 2005-06-07 | 2006-06-07 | 作为长效止痛剂的能抑制NGF与TrkA受体的结合的分子 |
KR1020087000315A KR101486085B1 (ko) | 2005-06-07 | 2006-06-07 | 연장된 효과를 가지는 진통제로서 NGF와 TrkA리셉터 사이의 결합을 억제할 수 있는 분자 |
EP06756318.9A EP1890726B1 (en) | 2005-06-07 | 2006-06-07 | Novel analgesic treatment with prolonged effect |
CA2611433A CA2611433C (en) | 2005-06-07 | 2006-06-07 | Novel analgesic treatment with prolonged effect using an anti-trka antibody |
AU2006256387A AU2006256387B2 (en) | 2005-06-07 | 2006-06-07 | Molecules that are able to inhibit the binding between NGF and the TrkA receptor as analgesics with prolonged effect |
US11/921,826 US9688749B2 (en) | 2005-06-07 | 2006-06-07 | Molecules that are able to inhibit the binding between NGF and the TrkA receptor as analgesics with prolonged effect |
NZ564071A NZ564071A (en) | 2005-06-07 | 2006-06-07 | Use of an anti-NGF IgG4 isotype antibody for treating and/or preventing chronic pain |
US11/921,398 US8691221B2 (en) | 2005-06-07 | 2006-06-07 | Analgesic treatment with prolonged effect |
JP2008515383A JP5133879B2 (ja) | 2005-06-07 | 2006-06-07 | NGFとTrkAレセプターとの結合を阻害することができる、長期化作用を有する鎮痛剤としての分子 |
PCT/IT2006/000427 WO2006131952A1 (en) | 2005-06-07 | 2006-06-07 | Novel analgesic treatment with prolonged effect |
JP2008515384A JP5730464B2 (ja) | 2005-06-07 | 2006-06-07 | 延長効果をもつ新規鎮痛治療 |
EP06756317A EP1893234A2 (en) | 2005-06-07 | 2006-06-07 | MOLECULES THAT ARE ABLE TO INHIBIT THE BINDING BETWEEN NGF AND THE TrkA RECEPTOR AS ANALGESICS WITH PROLONGED EFFECT |
RU2007147625/15A RU2427387C2 (ru) | 2005-06-07 | 2006-06-07 | МОЛЕКУЛЫ, СПОСОБНЫЕ ИНГИБИРОВАТЬ СВЯЗЫВАНИЕ МЕЖДУ NGF И РЕЦЕПТОРОМ TrkA, В КАЧЕСТВЕ АНАЛЬГЕТИКОВ С ПРОЛОНГИРОВАННЫМ ЭФФЕКТОМ |
DK06756318.9T DK1890726T3 (en) | 2005-06-07 | 2006-06-07 | New analgesic treatment with extended effect |
PCT/IT2006/000426 WO2006131951A2 (en) | 2005-06-07 | 2006-06-07 | MOLECULES THAT ARE ABLE TO INHIBIT THE BINDING BETWEEN NGF AND THE TrkA RECEPTOR AS ANALGESICS WITH PROLONGED EFFECT |
EP11188102A EP2484380A1 (en) | 2005-06-07 | 2006-06-07 | Molecules that are able to inhibit the binding between NGF and the TrkA receptor as analgesics with prolonged effect |
CA002610596A CA2610596A1 (en) | 2005-06-07 | 2006-06-07 | Molecules that are able to inhibit the binding between ngf and the trka receptor as analgesics with prolonged effect |
MX2007015487A MX2007015487A (es) | 2005-06-07 | 2006-06-07 | Moleculas que son capaces de inhibir la union entre el factor de crecimiento de nervios y el receptor trka como analgesicos con efecto prolongado. |
NO20080084A NO20080084L (no) | 2005-06-07 | 2008-01-07 | Molekyler som er i stand til a hemme bindingen mellom NGF og TrkA-reseptoren som analgetika med forlenget effekt |
HK09101888.4A HK1121403A1 (en) | 2005-06-07 | 2009-02-27 | Molecules that are able to inhibit the binding between ngf and the trka receptor as analgesics with prolonged effect |
JP2012106277A JP2012158604A (ja) | 2005-06-07 | 2012-05-07 | NGFとTrkAレセプターとの結合を阻害することができる、長期化作用を有する鎮痛剤としての分子 |
JP2013037304A JP2013151509A (ja) | 2005-06-07 | 2013-02-27 | 延長効果をもつ新規鎮痛治療 |
JP2014163809A JP2014218513A (ja) | 2005-06-07 | 2014-08-11 | NGFとTrkAレセプターとの結合を阻害することができる、長期化作用を有する鎮痛剤としての分子 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000290A ITRM20050290A1 (it) | 2005-06-07 | 2005-06-07 | Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato. |
Publications (1)
Publication Number | Publication Date |
---|---|
ITRM20050290A1 true ITRM20050290A1 (it) | 2006-12-08 |
Family
ID=37056613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT000290A ITRM20050290A1 (it) | 2005-06-07 | 2005-06-07 | Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato. |
Country Status (15)
Country | Link |
---|---|
US (2) | US9688749B2 (it) |
EP (3) | EP2484380A1 (it) |
JP (5) | JP5730464B2 (it) |
KR (1) | KR101486085B1 (it) |
CN (1) | CN101277718B (it) |
AU (1) | AU2006256387B2 (it) |
CA (2) | CA2610596A1 (it) |
DK (1) | DK1890726T3 (it) |
HK (1) | HK1121403A1 (it) |
IT (1) | ITRM20050290A1 (it) |
MX (1) | MX2007015487A (it) |
NO (1) | NO20080084L (it) |
NZ (1) | NZ564071A (it) |
RU (1) | RU2427387C2 (it) |
WO (2) | WO2006131952A1 (it) |
Families Citing this family (100)
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ITRM20030601A1 (it) | 2003-12-24 | 2005-06-25 | Lay Line Genomics Spa | Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti. |
ITRM20050290A1 (it) | 2005-06-07 | 2006-12-08 | Lay Line Genomics Spa | Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato. |
AU2007338791B2 (en) * | 2006-12-21 | 2014-03-13 | Amgen Inc | Stable buffered formulations containing polypeptides |
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US8591898B2 (en) | 2007-12-17 | 2013-11-26 | Pfizer Limited | Treatment of interstitial cystitis |
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SG192489A1 (en) | 2008-07-08 | 2013-08-30 | Abbott Lab | Prostaglandin e2 dual variable domain immunoglobulins and uses thereof |
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WO2010033941A1 (en) | 2008-09-22 | 2010-03-25 | Array Biopharma Inc. | Substituted imidazo[1,2b]pyridazine compounds as trk kinase inhibitors |
UY32192A (es) | 2008-10-22 | 2011-05-31 | Array Biopharma Inc | COMPUESTOS PIRAZOLO[1,5-a]PIRIMIDINA SUSTITUIDA COMO INHIBIDORES DE TRK CINASA |
US9040508B2 (en) * | 2008-12-08 | 2015-05-26 | Vm Pharma Llc | Compositions of protein receptor tyrosine kinase inhibitors |
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TWI486171B (zh) | 2009-05-04 | 2015-06-01 | 亞培研究公司 | 具有增進之體內穩定性之抗神經生長因子(ngf)抗體 |
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US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
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-
2005
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-
2006
- 2006-06-07 CA CA002610596A patent/CA2610596A1/en not_active Abandoned
- 2006-06-07 EP EP11188102A patent/EP2484380A1/en not_active Withdrawn
- 2006-06-07 CN CN2006800288760A patent/CN101277718B/zh not_active Expired - Fee Related
- 2006-06-07 US US11/921,826 patent/US9688749B2/en not_active Expired - Fee Related
- 2006-06-07 DK DK06756318.9T patent/DK1890726T3/en active
- 2006-06-07 US US11/921,398 patent/US8691221B2/en active Active
- 2006-06-07 KR KR1020087000315A patent/KR101486085B1/ko not_active IP Right Cessation
- 2006-06-07 AU AU2006256387A patent/AU2006256387B2/en not_active Ceased
- 2006-06-07 EP EP06756318.9A patent/EP1890726B1/en active Active
- 2006-06-07 EP EP06756317A patent/EP1893234A2/en not_active Withdrawn
- 2006-06-07 WO PCT/IT2006/000427 patent/WO2006131952A1/en active Application Filing
- 2006-06-07 NZ NZ564071A patent/NZ564071A/en not_active IP Right Cessation
- 2006-06-07 JP JP2008515384A patent/JP5730464B2/ja not_active Expired - Fee Related
- 2006-06-07 CA CA2611433A patent/CA2611433C/en active Active
- 2006-06-07 WO PCT/IT2006/000426 patent/WO2006131951A2/en active Application Filing
- 2006-06-07 MX MX2007015487A patent/MX2007015487A/es active IP Right Grant
- 2006-06-07 RU RU2007147625/15A patent/RU2427387C2/ru not_active IP Right Cessation
- 2006-06-07 JP JP2008515383A patent/JP5133879B2/ja not_active Expired - Fee Related
-
2008
- 2008-01-07 NO NO20080084A patent/NO20080084L/no unknown
-
2009
- 2009-02-27 HK HK09101888.4A patent/HK1121403A1/xx not_active IP Right Cessation
-
2012
- 2012-05-07 JP JP2012106277A patent/JP2012158604A/ja not_active Withdrawn
-
2013
- 2013-02-27 JP JP2013037304A patent/JP2013151509A/ja active Pending
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2014
- 2014-08-11 JP JP2014163809A patent/JP2014218513A/ja active Pending
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