ITRM20040212A1 - Animale transgenico non umano come modello per malattie neurodegenerative e per la loro diagnosi precoce. - Google Patents

Animale transgenico non umano come modello per malattie neurodegenerative e per la loro diagnosi precoce.

Info

Publication number
ITRM20040212A1
ITRM20040212A1 IT000212A ITRM20040212A ITRM20040212A1 IT RM20040212 A1 ITRM20040212 A1 IT RM20040212A1 IT 000212 A IT000212 A IT 000212A IT RM20040212 A ITRM20040212 A IT RM20040212A IT RM20040212 A1 ITRM20040212 A1 IT RM20040212A1
Authority
IT
Italy
Prior art keywords
model
neurodegenerative diseases
transgenic animal
early diagnosis
human transgenic
Prior art date
Application number
IT000212A
Other languages
English (en)
Inventor
Simona Capsoni
Antonino Cattaneo
Original Assignee
Lay Line Genomics Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lay Line Genomics Spa filed Critical Lay Line Genomics Spa
Priority to IT000212A priority Critical patent/ITRM20040212A1/it
Publication of ITRM20040212A1 publication Critical patent/ITRM20040212A1/it
Priority to JP2007510244A priority patent/JP2008505615A/ja
Priority to US11/579,108 priority patent/US20070253907A1/en
Priority to AU2005238317A priority patent/AU2005238317A1/en
Priority to CA002565068A priority patent/CA2565068A1/en
Priority to EP05742908A priority patent/EP1748689A2/en
Priority to PCT/IT2005/000249 priority patent/WO2005105847A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
IT000212A 2004-04-30 2004-04-30 Animale transgenico non umano come modello per malattie neurodegenerative e per la loro diagnosi precoce. ITRM20040212A1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT000212A ITRM20040212A1 (it) 2004-04-30 2004-04-30 Animale transgenico non umano come modello per malattie neurodegenerative e per la loro diagnosi precoce.
JP2007510244A JP2008505615A (ja) 2004-04-30 2005-04-29 神経変性疾患及びその早期診断のためのモデルとしての非ヒトトランスジェニック動物
US11/579,108 US20070253907A1 (en) 2004-04-30 2005-04-29 Non Human Transgenic Animal as Model of Neurodegenerative Diseases and for the Early Diagnosis Thereof
AU2005238317A AU2005238317A1 (en) 2004-04-30 2005-04-29 Non human transgenic animal as a model of neurodegenerative diseases and for the early diagnosis thereof
CA002565068A CA2565068A1 (en) 2004-04-30 2005-04-29 Non human transgenic animal as a model of neurodegenerative diseases and for the early diagnosis thereof
EP05742908A EP1748689A2 (en) 2004-04-30 2005-04-29 Non human transgenic animal as a model of neurodegenerative diseases and for the early diagnosis thereof
PCT/IT2005/000249 WO2005105847A2 (en) 2004-04-30 2005-04-29 Non human transgenic animal as a model of neurodegenerative diseases and for the early diagnosis thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000212A ITRM20040212A1 (it) 2004-04-30 2004-04-30 Animale transgenico non umano come modello per malattie neurodegenerative e per la loro diagnosi precoce.

Publications (1)

Publication Number Publication Date
ITRM20040212A1 true ITRM20040212A1 (it) 2004-07-30

Family

ID=34979491

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000212A ITRM20040212A1 (it) 2004-04-30 2004-04-30 Animale transgenico non umano come modello per malattie neurodegenerative e per la loro diagnosi precoce.

Country Status (7)

Country Link
US (1) US20070253907A1 (it)
EP (1) EP1748689A2 (it)
JP (1) JP2008505615A (it)
AU (1) AU2005238317A1 (it)
CA (1) CA2565068A1 (it)
IT (1) ITRM20040212A1 (it)
WO (1) WO2005105847A2 (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
KR101300315B1 (ko) 2003-12-17 2013-08-28 프래시스 파마슈티컬즈 인코포레이티드 코드된 라이브러리의 합성 방법
ITRM20030601A1 (it) 2003-12-24 2005-06-25 Lay Line Genomics Spa Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti.
ITRM20050290A1 (it) 2005-06-07 2006-12-08 Lay Line Genomics Spa Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
DK1954718T3 (en) 2005-11-30 2014-12-15 Abbvie Inc Anti-A-globulomer antibodies antigenbindingsgrupper thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods for producing said antibodies,
RU2432362C2 (ru) 2005-11-30 2011-10-27 Эбботт Лэборетриз Моноклональные антитела и их применения
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
US20100311767A1 (en) 2007-02-27 2010-12-09 Abbott Gmbh & Co. Kg Method for the treatment of amyloidoses
SI2448970T1 (sl) 2009-05-04 2014-11-28 Abbvie Research B.V. Protitelesa proti živčnemu rastnemu faktorju (NGF) s povečano stabilnostjo in vivo
MX336196B (es) 2010-04-15 2016-01-11 Abbvie Inc Proteinas de union a amiloide beta.
MX358739B (es) 2010-08-14 2018-09-03 Abbvie Inc Star Proteinas de union a amiloide beta.
US9783601B2 (en) 2010-12-01 2017-10-10 Alderbio Holdings Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
CA2835094C (en) * 2011-05-06 2020-12-22 David Gearing Anti-nerve growth factor antibodies and methods of preparing and using the same
CN114903006A (zh) * 2021-02-09 2022-08-16 中国科学院脑科学与智能技术卓越创新中心 一种非人灵长类动物物质成瘾模型的构建方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU783964B2 (en) * 1999-08-06 2006-01-05 S.I.S.S.A. Scuola Internazionale Superiore Di Studi Avanzati Non-human transgenic animals for the study of neurodegenerative syndromes

Also Published As

Publication number Publication date
WO2005105847A3 (en) 2006-03-16
CA2565068A1 (en) 2005-11-10
JP2008505615A (ja) 2008-02-28
US20070253907A1 (en) 2007-11-01
EP1748689A2 (en) 2007-02-07
AU2005238317A1 (en) 2005-11-10
WO2005105847A2 (en) 2005-11-10

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