DK1265605T3 - Farmaceutiske sammensætninger omfattende peptidmimetisk, cyklisk beta-drejningsforbindelse - Google Patents

Farmaceutiske sammensætninger omfattende peptidmimetisk, cyklisk beta-drejningsforbindelse

Info

Publication number
DK1265605T3
DK1265605T3 DK01942551T DK01942551T DK1265605T3 DK 1265605 T3 DK1265605 T3 DK 1265605T3 DK 01942551 T DK01942551 T DK 01942551T DK 01942551 T DK01942551 T DK 01942551T DK 1265605 T3 DK1265605 T3 DK 1265605T3
Authority
DK
Denmark
Prior art keywords
trka
extracellular domain
pharmaceutical compositions
compounds
peptide mimetic
Prior art date
Application number
DK01942551T
Other languages
English (en)
Inventor
Kevin Burgess
Horacio Uri Saragovi
Original Assignee
Univ Mcgill
Texas A & M Univ Sys
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mcgill, Texas A & M Univ Sys filed Critical Univ Mcgill
Application granted granted Critical
Publication of DK1265605T3 publication Critical patent/DK1265605T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
DK01942551T 2000-01-18 2001-01-18 Farmaceutiske sammensætninger omfattende peptidmimetisk, cyklisk beta-drejningsforbindelse DK1265605T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17648200P 2000-01-18 2000-01-18
PCT/CA2001/000043 WO2001052843A1 (en) 2000-01-18 2001-01-18 β-TURN PEPTIDOMIMETIC CYCLIC COMPOUNDS

Publications (1)

Publication Number Publication Date
DK1265605T3 true DK1265605T3 (da) 2007-02-12

Family

ID=22644525

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01942551T DK1265605T3 (da) 2000-01-18 2001-01-18 Farmaceutiske sammensætninger omfattende peptidmimetisk, cyklisk beta-drejningsforbindelse

Country Status (9)

Country Link
US (1) US6881719B2 (da)
EP (1) EP1265605B1 (da)
AT (1) ATE340571T1 (da)
AU (1) AU2001228212A1 (da)
CA (1) CA2397670C (da)
DE (1) DE60123399T2 (da)
DK (1) DK1265605T3 (da)
ES (1) ES2273849T3 (da)
WO (1) WO2001052843A1 (da)

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US7566765B2 (en) * 2000-03-06 2009-07-28 Rigel Pharmaceuticals, Inc. Heterocyclic compounds containing a nine-membered carbon-nitrogen ring
DK1575477T3 (da) * 2001-05-25 2012-07-23 Cornell Res Foundation Inc Højaffinitetsligand til p75-neurotrofinreceptor
AUPR604401A0 (en) 2001-06-29 2001-07-26 University Of Wollongong, The Peptoid compounds
DK1575517T3 (da) 2002-12-24 2012-05-14 Rinat Neuroscience Corp Anti-ngf-antistoffer og fremgangsmåder til anvendelse af samme
US9498530B2 (en) 2002-12-24 2016-11-22 Rinat Neuroscience Corp. Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
SI1606409T1 (sl) 2003-03-19 2011-01-31 Biogen Idec Inc Vezavni protein receptorja Nogo
DK1633774T3 (da) 2003-06-18 2010-05-25 Tranzyme Pharma Inc Makrocykliske motilinreceptorantagonister
ITRM20030601A1 (it) * 2003-12-24 2005-06-25 Lay Line Genomics Spa Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti.
ES2395094T3 (es) 2004-06-24 2013-02-08 Biogen Idec Ma Inc. Tratamiento de afecciones que implican la desmielinización
EP1771572B1 (en) 2004-07-14 2008-10-15 Janssen Pharmaceutica N.V. P75ntr screening assay for identifying modulators of apoptosis
JP2008516979A (ja) * 2004-10-14 2008-05-22 リゲル ファーマシューティカルズ インコーポレーティッド Ｉｒｅｓ仲介性翻訳の複素環式阻害剤およびその使用法
WO2006113097A2 (en) * 2005-04-15 2006-10-26 The University Of North Carolina At Chapel Hill Methods of facilitating cell survival using neurotrophin mimetics
US20110230479A1 (en) * 2005-04-15 2011-09-22 Longo Frank M Neurotrophin mimetics and uses thereof
ITRM20050290A1 (it) * 2005-06-07 2006-12-08 Lay Line Genomics Spa Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
JP5461009B2 (ja) 2005-06-08 2014-04-02 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 非ペプチド及びペプチドｂｄｎｆニューロトロフィン類似体を用いた神経細胞生存促進法
BRPI0613387A2 (pt) 2005-07-08 2011-01-11 Biogen Idec Inc anticorpo isolado ou fragmento de ligação de antìgeno deste e o seu uso, polinucleotìdeo isolado, composição, vetor, célula hospedeira, anticorpo anti-sp35 e método para a produção do mesmo, polipeptìdeo isolado, método in vitro para redução da inibição do crescimento axonal e método in vitro para inibição do crescimento do colapso do cone
EP2068866A4 (en) 2006-07-24 2010-04-07 Biogen Idec Inc METHODS FOR PROMOTING MYELINIZATION, NEURONAL SURVIVAL AND DIFFERENTIATION OF OLIGODENDROCYTES BY ADMINISTERING SP35 OR TRKA ANTAGONISTS
AU2011253937B2 (en) * 2006-12-05 2012-09-27 The Royal Institution For The Advancement Of Learning/ Mcgill University Methods of use of TRK receptor modulators
CN101657212B (zh) * 2006-12-05 2014-03-19 皇家学习促进会/麦吉尔大学 Trk受体调节剂的使用方法
WO2009048605A1 (en) * 2007-10-11 2009-04-16 Biogen Idec Ma Inc. Methods for treating pressure induced optic neuropathy, preventing neuronal degeneration and promoting neuronal cell, survival via administration of lingo-1 antagonists and trkb agonists
JP5754046B2 (ja) * 2007-11-08 2015-07-22 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． 脱髄を伴う状態の治療におけるｌｉｎｇｏ−４アンタゴニストの使用
AU2009232352B2 (en) 2008-04-04 2013-09-05 Mimetogen Pharmaceuticals Inc. Beta-turn peptidomimetic cyclic compounds for treating dry eye
US8058406B2 (en) 2008-07-09 2011-11-15 Biogen Idec Ma Inc. Composition comprising antibodies to LINGO or fragments thereof
EP2400977B1 (en) * 2009-02-27 2014-07-23 Mimetogen Pharmaceuticals Inc. Peptidomimetic cyclic compounds for treating retinitis pigmentosa
US10273219B2 (en) 2009-11-12 2019-04-30 Pharmatrophix, Inc. Crystalline forms of neurotrophin mimetic compounds and their salts
CN102740856B (zh) 2009-11-12 2015-02-18 特罗菲克斯制药股份有限公司 神经营养蛋白模拟化合物及其盐的晶型
EA030716B1 (ru) 2012-05-14 2018-09-28 Байоджен Ма Инк. Антагонисты lingo-2 для лечения заболеваний, в которых участвуют двигательные нейроны
EP2864347B1 (en) * 2012-06-22 2020-10-28 Mimetogen Pharmaceuticals, Inc. Synthesis of beta-turn peptidomimetic cyclic compounds
CA2901844A1 (en) 2013-03-15 2014-09-18 Pharmatrophix, Inc. Non-peptide bdnf neurotrophin mimetics
EP2970105B1 (en) 2013-03-15 2019-09-11 Pharmatrophix Inc. Non-peptide bdnf neurotrophin mimetics
CA2923160A1 (en) 2013-09-09 2015-03-12 Canimguide Therapeutics Ab Immune system modulators
AU2016205197B2 (en) 2015-01-08 2021-10-21 Biogen Ma Inc. LINGO-1 antagonists and uses for treatment of demyelinating disorders
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EP4180446A1 (en) * 2020-07-10 2023-05-17 The University of Tokyo Cyclic peptide, peptide complex, and drug composition containing said cyclic peptide and/or said peptide complex

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GB9402331D0 (en) * 1994-02-07 1994-03-30 Univ Mcgill Nerve growth factor structural analogs and their uses

Also Published As

Publication number Publication date
US20030211982A1 (en) 2003-11-13
EP1265605A1 (en) 2002-12-18
US6881719B2 (en) 2005-04-19
AU2001228212A1 (en) 2001-07-31
CA2397670C (en) 2010-06-08
DE60123399D1 (de) 2006-11-09
ATE340571T1 (de) 2006-10-15
EP1265605B1 (en) 2006-09-27
WO2001052843A1 (en) 2001-07-26
DE60123399T2 (de) 2007-08-23
CA2397670A1 (en) 2001-07-26
ES2273849T3 (es) 2007-05-16

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