ATE227276T1 - Neue pyrimidinderivate - Google Patents

Neue pyrimidinderivate

Info

Publication number
ATE227276T1
ATE227276T1 AT98934105T AT98934105T ATE227276T1 AT E227276 T1 ATE227276 T1 AT E227276T1 AT 98934105 T AT98934105 T AT 98934105T AT 98934105 T AT98934105 T AT 98934105T AT E227276 T1 ATE227276 T1 AT E227276T1
Authority
AT
Austria
Prior art keywords
pyrimidine derivatives
new pyrimidine
new
purinoceptor
transmembrane
Prior art date
Application number
AT98934105T
Other languages
English (en)
Inventor
Nicholas Kindon
Premji Meghani
Stephen Thom
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE227276T1 publication Critical patent/ATE227276T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98934105T 1997-07-24 1998-07-15 Neue pyrimidinderivate ATE227276T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9702794A SE9702794D0 (sv) 1997-07-24 1997-07-24 New compounds
PCT/SE1998/001391 WO1999005123A1 (en) 1997-07-24 1998-07-15 Novel pyrimidin derivatives

Publications (1)

Publication Number Publication Date
ATE227276T1 true ATE227276T1 (de) 2002-11-15

Family

ID=20407823

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98934105T ATE227276T1 (de) 1997-07-24 1998-07-15 Neue pyrimidinderivate

Country Status (8)

Country Link
US (1) US6200981B1 (de)
EP (1) EP1000038B1 (de)
JP (1) JP2001510833A (de)
AT (1) ATE227276T1 (de)
AU (1) AU8370498A (de)
DE (1) DE69809242D1 (de)
SE (1) SE9702794D0 (de)
WO (1) WO1999005123A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1356299A (en) * 1997-11-21 1999-06-15 Astra Pharmaceuticals Limited New compounds which are p2-purinoceptor 7-transmembrane (tm) g-protein coupled receptor antagonists
US7179481B2 (en) * 2002-09-19 2007-02-20 Kimberly-Clark Worldwide, Inc. Vaginal health products
US7098189B2 (en) * 2002-12-16 2006-08-29 Kimberly-Clark Worldwide, Inc. Wound and skin care compositions
US7056889B2 (en) 2002-12-16 2006-06-06 Kimberly-Clark, Worldwide, Inc. Compounds that bind P2Y2 or P2Y1 receptors
US7485666B2 (en) * 2004-06-17 2009-02-03 Kimberly-Clark Worldwide, Inc. Vaginal health products
MX2007014114A (es) 2005-05-10 2008-03-14 Intermune Inc Derivados de piridona para modular el sistema de proteina cinasa activada por estres.
RU2403250C2 (ru) 2005-06-02 2010-11-10 Ф.Хоффманн-Ля Рош Аг Производные пиперидин-4-иламида и их применение в качестве антагонистов рецептора sst подтипа 5
CA3034994A1 (en) 2008-06-03 2009-12-10 Intermune, Inc. Substituted aryl-2 pyridone compounds and use thereof for treating inflammatory and fibrotic disorders
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
CN106459042B (zh) 2014-04-02 2019-06-28 英特穆恩公司 抗纤维化吡啶酮类

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6930196A (en) * 1995-09-12 1997-04-01 Bayer Aktiengesellschaft Uracil derivative

Also Published As

Publication number Publication date
US6200981B1 (en) 2001-03-13
SE9702794D0 (sv) 1997-07-24
JP2001510833A (ja) 2001-08-07
EP1000038B1 (de) 2002-11-06
AU8370498A (en) 1999-02-16
DE69809242D1 (de) 2002-12-12
WO1999005123A1 (en) 1999-02-04
EP1000038A1 (de) 2000-05-17

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Legal Events

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